Strain Name:
C57BL/6J-MtgxR0931Btlr/Mmmh
Stock Number:
039075-MU
Citation ID:
RRID:MMRRC_039075-MU
Other Names:
R0931 (G1), C57BL/6J-MtgxR0931Btlr
Major Collection:

Gene Information

Crabp1
Name: cellular retinoic acid binding protein I
Synonyms: CrabpI, Rbp-5, Crabp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12903
HGNC: HGNC:2338
Homologene: 3222
Ddx1
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Wdr7
Name: WD repeat domain 7
Synonyms: TGF-beta resistance associated gene, TRAG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104082
VEGA: 18
Homologene: 11408
Rasa2
Name: RAS p21 protein activator 2
Synonyms: 5430433H21Rik, GAP1m
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114713
HGNC: HGNC:9872
Homologene: 4745
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2A-HUB, 2310047C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224170
Homologene: 8771
Cspp1
Name: centrosome and spindle pole associated protein 1
Synonyms: 2310020J12Rik, 4930413O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211660
Homologene: 23487
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 5930437A14Rik, 6720426B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77739
Homologene: 64642
Exosc1
Name: exosome component 1
Synonyms: 2610312F07Rik, 2610104C07Rik, 2610035C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66583
VEGA: 19
Homologene: 9359
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Pdcd1
Name: programmed cell death 1
Synonyms: Pdc1, PD-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18566
HGNC: HGNC:8760
Homologene: 3681
Ccr1
Name: chemokine (C-C motif) receptor 1
Synonyms: Cmkbr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12768
VEGA: 9
HGNC: HGNC:1602
Homologene: 20344
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212124
Fam160a1
Name: family with sequence similarity 160, member A1
Synonyms: 9930021J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229488
Homologene: 85149
Ttn
Name: titin
Synonyms: mdm, 2310036G12Rik, D830007G01Rik, shru, L56, 2310074I15Rik, 2310057K23Rik, connectin, D330041I19Rik, 1100001C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Arhgap20
Name: Rho GTPase activating protein 20
Synonyms: 6530403F17Rik, A530023E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244867
Homologene: 18938
Astn2
Name: astrotactin 2
Synonyms: Astnl, 1d8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56079
Homologene: 77850
Psmc1
Name: protease (prosome, macropain) 26S subunit, ATPase 1
Synonyms: S4, P26s4, rpt2, Rpt2/S4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19179
VEGA: 12
HGNC: HGNC:9547
Homologene: 2095
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Taar1
Name: trace amine-associated receptor 1
Synonyms: Trar1, Tar1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 111174
VEGA: 10
Homologene: 24938
Aknad1
Name: AKNA domain containing 1
Synonyms: 4921525H12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329738
Homologene: 51892
Gas7
Name: growth arrest specific 7
Synonyms: B230343A10Rik, Gas7-cb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14457
HGNC: HGNC:4169
Homologene: 69015
Ssu2
Name: ssu-2 homolog (C. elegans)
Synonyms: D630042P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243612
Homologene: 136556
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50720
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Papolg
Name: poly(A) polymerase gamma
Synonyms: 9630006B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216578
Homologene: 56959
Myrfl
Name: myelin regulatory factor-like
Synonyms: Gm239, LOC237558
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237558
VEGA: 10
Homologene: 88588
Olfr691
Name: olfactory receptor 691
Synonyms: MOR31-6, GA_x6K02T2PBJ9-7966695-7965727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259063
Homologene: 17483
Gss
Name: glutathione synthetase
Synonyms: GS-A/GS-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14854
HGNC: HGNC:4624
Homologene: 148
Klk1b4
Name: kallikrein 1-related pepidase b4
Synonyms: Ngfa, Ngfa, mGk-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18048
HGNC: HGNC:6364
Homologene: 68141
Vmn2r49
Name: vomeronasal 2, receptor 49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625605
Homologene: 113703
Col8a1
Name: collagen, type VIII, alpha 1
Synonyms: Col8a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12837
HGNC: HGNC:2215
Homologene: 22423
Setdb2
Name: SET domain, bifurcated 2
Synonyms: LOC239122, KMT1F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239122
Homologene: 12903
Ajm1
Name: apical junction component 1
Synonyms: LOC381353, Gm996
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381353
Homologene: 19943
Irx2
Name: Iroquois homeobox 2
Synonyms: IRX6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16372
Homologene: 56490
Zfp324
Name: zinc finger protein 324
Synonyms: D430030K24Rik, ZF5128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243834
Homologene: 8648
Hdhd3
Name: haloacid dehalogenase-like hydrolase domain containing 3
Synonyms: 2810435D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72748
Homologene: 11497
Mettl27
Name: methyltransferase like 27
Synonyms: Wbscr27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 79565
Homologene: 11553
Cpa2
Name: carboxypeptidase A2, pancreatic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232680
HGNC: HGNC:2297
Homologene: 37541
Olfr455
Name: olfactory receptor 455
Synonyms: Olfr455-ps1, EG546896, MOR0-2P, MOR0-17_p, GA_x6K02T2P3E9-5021913-5022918, MORO-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 546896
Homologene: 67366
Klri1
Name: killer cell lectin-like receptor family I member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 503550
Homologene: 86735
Kcnf1
Name: potassium voltage-gated channel, subfamily F, member 1
Synonyms: LOC382571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 382571
HGNC: HGNC:6246
Homologene: 124236
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 10,104,286 bp
  • T to G, chromosome 1 at 46,099,612 bp
  • A to G, chromosome 1 at 94,039,513 bp
  • T to C, chromosome 2 at 25,578,489 bp
  • A to G, chromosome 2 at 76,781,502 bp
  • A to G, chromosome 2 at 112,653,702 bp
  • A to T, chromosome 2 at 155,567,689 bp
  • A to G, chromosome 3 at 85,673,243 bp
  • T to C, chromosome 3 at 108,752,023 bp
  • G to A, chromosome 4 at 62,499,520 bp
  • A to G, chromosome 4 at 65,648,293 bp
  • G to A, chromosome 4 at 86,249,847 bp
  • T to C, chromosome 5 at 134,934,431 bp
  • T to C, chromosome 6 at 30,552,071 bp
  • C to A, chromosome 6 at 42,538,086 bp
  • C to A, chromosome 6 at 112,384,398 bp
  • A to T, chromosome 6 at 129,697,418 bp
  • T to C, chromosome 7 at 9,986,398 bp
  • A to G, chromosome 7 at 12,966,258 bp
  • T to C, chromosome 7 at 44,211,056 bp
  • A to T, chromosome 7 at 105,337,529 bp
  • T to C, chromosome 7 at 139,655,841 bp
  • A to G, chromosome 9 at 51,816,741 bp
  • T to C, chromosome 9 at 54,768,433 bp
  • A to T, chromosome 9 at 96,552,404 bp
  • C to A, chromosome 9 at 123,963,790 bp
  • A to T, chromosome 10 at 23,921,283 bp
  • T to A, chromosome 10 at 116,839,449 bp
  • A to G, chromosome 11 at 23,882,257 bp
  • A to T, chromosome 11 at 67,652,925 bp
  • A to T, chromosome 12 at 13,237,817 bp
  • C to T, chromosome 12 at 13,331,114 bp
  • T to C, chromosome 12 at 17,175,141 bp
  • T to C, chromosome 12 at 100,119,082 bp
  • T to A, chromosome 13 at 72,631,556 bp
  • A to G, chromosome 14 at 59,423,496 bp
  • G to A, chromosome 14 at 61,203,495 bp
  • A to G, chromosome 16 at 48,951,558 bp
  • A to G, chromosome 16 at 57,628,568 bp
  • T to C, chromosome 18 at 63,865,300 bp
  • A to G, chromosome 19 at 41,933,237 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0931 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039075-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.