Strain Name:
C57BL/6J-MtgxR0942Btlr/Mmmh
Stock Number:
039081-MU
Citation ID:
RRID:MMRRC_039081-MU
Other Names:
R0942 (G1), C57BL/6J-MtgxR0942Btlr
Major Collection:

Strain Information

Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Rprd2
Name: regulation of nuclear pre-mRNA domain containing 2
Synonyms: 2810036A19Rik, 4930535B03Rik, 6720469I21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75137
Homologene: 19997
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Mhdadsk9, Dsk9, Nf-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Taf15
Name: TATA-box binding protein associated factor 15
Synonyms: 68kDa, TAFII68, 2610111C21Rik, Taf2n
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70439
Homologene: 131088
Rif1
Name: replication timing regulatory factor 1
Synonyms: 6530403D07Rik, D2Ertd145e, 5730435J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51869
Homologene: 41231
Ascc2
Name: activating signal cointegrator 1 complex subunit 2
Synonyms: 1700011I11Rik, 2610034L15Rik, ASC1p100
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 75452
Homologene: 41774
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: Bolvr, mBLVR1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Mib2
Name: mindbomb E3 ubiquitin protein ligase 2
Synonyms: 2210008I11Rik, Zzank1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76580
Homologene: 16062
Gpc1
Name: glypican 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14733
HGNC: HGNC:4449
Homologene: 20477
Ptprc
Name: protein tyrosine phosphatase receptor type C
Synonyms: T200, Lyt-4, Ly-5, B220, CD45
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Brms1l
Name: breast cancer metastasis-suppressor 1-like
Synonyms: BRMS1, 0710008O11Rik, D12Ertd407e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 52592
VEGA: 12
Homologene: 9123
Il17d
Name: interleukin 17D
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239114
VEGA: 14
HGNC: HGNC:5984
Homologene: 16284
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: B930097C17Rik, MPP-9, MPP9, 4930548D04Rik, 9630025B04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Atad2b
Name: ATPase family, AAA domain containing 2B
Synonyms: 1110014E10Rik, D530031C13Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320817
VEGA: 12
Homologene: 86351
Pkp2
Name: plakophilin 2
Synonyms: 1200012P04Rik, 1200008D14Rik, Pkp2l
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67451
HGNC: HGNC:9024
Homologene: 3364
Il16
Name: interleukin 16
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16170
HGNC: HGNC:5980
Homologene: 18157
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: mdfw, ahl, nmf112, nmf252, 4930542A03Rik, nmf181, sals, USH1D, bob
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Grb7
Name: growth factor receptor bound protein 7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14786
HGNC: HGNC:4567
Homologene: 3881
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Enpp4
Name: ectonucleotide pyrophosphatase/phosphodiesterase 4
Synonyms: 4933413N07Rik, LOC224794
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224794
HGNC: HGNC:3359
Homologene: 28264
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: fibrocystin L, PKHDL1, D86 mRNA
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Dner
Name: delta/notch-like EGF repeat containing
Synonyms: A930026D19Rik, BET
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227325
Homologene: 26722
Or14c40
Name: olfactory receptor family 14 subfamily C member 40
Synonyms: MOR221-3, Olfr293, GA_x6K02T2NHDJ-9457744-9456734
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257906
Homologene: 79385
Nek11
Name: NIMA (never in mitosis gene a)-related expressed kinase 11
Synonyms: 4932416N14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208583
Homologene: 57008
Tshz1
Name: teashirt zinc finger family member 1
Synonyms: 5730407I04Rik, D18Bwg1409e, Mtsh1, Tsh1, Sdccag33, NY-CO-33, teashirt1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 110796
Homologene: 4227
Ppp1r16a
Name: protein phosphatase 1, regulatory subunit 16A
Synonyms: 2900084E10Rik, R75527, Mypt3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73062
Homologene: 13161
1810064F22Rik
Name: RIKEN cDNA 1810064F22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69862
Abcb5
Name: ATP-binding cassette, sub-family B member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: LOC268884, 9530025L16Rik, 4632417D23Rik, 5530401I02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77446
Homologene: 35276
Abcd4
Name: ATP-binding cassette, sub-family D member 4
Synonyms: Pxmp1l, P69r
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19300
VEGA: 12
HGNC: HGNC:68
Homologene: 3703
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 30956
Homologene: 4212
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: A230044C21Rik, Caps2, cpd2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320405
Homologene: 23060
Cenpj
Name: centromere protein J
Synonyms: Sas4, 4932437H03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219103
Homologene: 10204
Acer3
Name: alkaline ceramidase 3
Synonyms: 5430429L08Rik, Phca, 1110057L18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66190
Homologene: 5410
Dzip1
Name: DAZ interacting protein 1
Synonyms: 2510025K24Rik, 2810422M04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66573
VEGA: 14
Homologene: 45708
Lrrc45
Name: leucine rich repeat containing 45
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217366
Homologene: 17019
Erich3
Name: glutamate rich 3
Synonyms: 5031409G23Rik, 4922501L14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 209601
Homologene: 27877
Speer1e
Name: spermatogenesis associated glutamate (E)-rich protein 1E
Synonyms: Gm5861
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 545728
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 84,585,309 bp
  • G to A, chromosome 1 at 92,857,309 bp
  • G to A, chromosome 1 at 118,837,506 bp
  • G to A, chromosome 1 at 138,068,401 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • T to C, chromosome 2 at 76,863,489 bp
  • A to T, chromosome 3 at 95,765,418 bp
  • T to A, chromosome 3 at 154,739,151 bp
  • C to T, chromosome 4 at 155,659,460 bp
  • A to T, chromosome 5 at 11,186,521 bp
  • A to T, chromosome 5 at 25,315,303 bp
  • T to A, chromosome 5 at 124,262,037 bp
  • C to T, chromosome 6 at 23,075,152 bp
  • T to A, chromosome 6 at 23,263,562 bp
  • T to A, chromosome 7 at 83,663,141 bp
  • T to A, chromosome 7 at 86,664,106 bp
  • T to C, chromosome 7 at 98,257,742 bp
  • C to T, chromosome 9 at 22,208,071 bp
  • T to A, chromosome 9 at 105,295,371 bp
  • A to T, chromosome 10 at 60,410,860 bp
  • A to T, chromosome 10 at 80,732,955 bp
  • T to A, chromosome 11 at 4,668,380 bp
  • T to C, chromosome 11 at 79,438,711 bp
  • T to C, chromosome 11 at 83,499,106 bp
  • T to C, chromosome 11 at 98,453,808 bp
  • T to C, chromosome 11 at 120,718,238 bp
  • T to A, chromosome 12 at 5,024,591 bp
  • T to C, chromosome 12 at 55,865,957 bp
  • A to G, chromosome 12 at 84,612,828 bp
  • C to A, chromosome 12 at 118,906,198 bp
  • A to G, chromosome 14 at 56,555,209 bp
  • C to T, chromosome 14 at 57,542,320 bp
  • T to A, chromosome 14 at 118,887,197 bp
  • T to C, chromosome 15 at 44,532,959 bp
  • T to C, chromosome 15 at 76,694,011 bp
  • G to T, chromosome 16 at 16,226,030 bp
  • T to C, chromosome 16 at 33,760,803 bp
  • A to T, chromosome 17 at 44,101,881 bp
  • A to G, chromosome 18 at 84,013,053 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0942 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039081-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.