Strain Name:
C57BL/6J-MtgxR0961Btlr/Mmmh
Stock Number:
039090-MU
Citation ID:
RRID:MMRRC_039090-MU
Other Names:
R0961 (G1), C57BL/6J-MtgxR0961Btlr
Major Collection:

Gene Information

Gnb5
Name: guanine nucleotide binding protein (G protein), beta 5
Synonyms: Gbeta5, G beta 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14697
VEGA: 9
HGNC: HGNC:4401
Homologene: 40714
Npr1
Name: natriuretic peptide receptor 1
Synonyms: GC-A, NPRA, guanylyl cyclase-A, NPR-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18160
HGNC: HGNC:7943
Homologene: 37367
Gon4l
Name: gon-4-like (C.elegans)
Synonyms: 2610100B20Rik, 1500041I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76022
Homologene: 13002
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alpha-fodrin, alphaII-spectrin, Spna2, Spna-2, 2610027H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Oxtr
Name: oxytocin receptor
Synonyms: OTR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18430
HGNC: HGNC:8529
Homologene: 20255
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Rere
Name: arginine glutamic acid dipeptide (RE) repeats
Synonyms: atrophin-2, eyem03Jus, 1110033A15Rik, Atr2, eyes3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68703
HGNC: HGNC:9965
Homologene: 8101
R3hdm1
Name: R3H domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226412
HGNC: HGNC:9757
Homologene: 9108
Gpat4
Name: glycerol-3-phosphate acyltransferase 4
Synonyms: Agpat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102247
Homologene: 32425
Ncbp1
Name: nuclear cap binding protein subunit 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433702
HGNC: HGNC:7658
Homologene: 1859
Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
Synonyms: Img, LIG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16206
Homologene: 7380
Lamc1
Name: laminin, gamma 1
Synonyms: Lamb2, laminin B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226519
HGNC: HGNC:6492
Homologene: 1724
Lmo7
Name: LIM domain only 7
Synonyms: LOC380928, FBXO20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 380928
HGNC: HGNC:6646
Homologene: 83924
Egfr
Name: epidermal growth factor receptor
Synonyms: Wa5, 9030024J15Rik, Errb1, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, Erbb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13649
HGNC: HGNC:3236
Homologene: 74545
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242553
Homologene: 18244
Phactr4
Name: phosphatase and actin regulator 4
Synonyms: 3110001B12Rik, C330013F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100169
Homologene: 41537
Kdm2a
Name: lysine (K)-specific demethylase 2A
Synonyms: Gm4560, Jhdm1a, Fbl7, lalina, 5530401A10Rik, Cxxc8, Fbxl11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225876
Homologene: 56564
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: calcium release channel isoform 1, skrr, Ryr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: tumstatin, alpha3(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Fbxw9
Name: F-box and WD-40 domain protein 9
Synonyms: Fbw9, 1110017H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68628
Homologene: 23598
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Mep1b
Name: meprin 1 beta
Synonyms: meprin beta, Mep-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17288
VEGA: 18
HGNC: HGNC:7020
Homologene: 48382
Gm4934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320631
Homologene: 87255
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213043
Homologene: 84622
Adcy8
Name: adenylate cyclase 8
Synonyms: AC8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11514
VEGA: 15
HGNC: HGNC:239
Homologene: 37443
Atg9a
Name: autophagy related 9A
Synonyms: Apg9l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 245860
Homologene: 34495
Myo15b
Name: myosin XVB
Synonyms: E330039G21Rik, LOC380737, LOC217328
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217328
Gstm7
Name: glutathione S-transferase, mu 7
Synonyms: 0610005A07Rik, Cd203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68312
HGNC: HGNC:4634
Homologene: 41816
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229900
Homologene: 138296
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208994
Homologene: 19478
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70950
VEGA: 18
Homologene: 12373
Slc26a4
Name: solute carrier family 26, member 4
Synonyms: Pds, pendrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 23985
VEGA: 12
HGNC: HGNC:8818
Homologene: 20132
F11
Name: coagulation factor XI
Synonyms: plasma thromboplastin antecedent, Cf11, 1600027G01Rik, FXI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Zfp759
Name: zinc finger protein 759
Synonyms: Rslcan-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 268670
VEGA: 13
Ccdc63
Name: coiled-coil domain containing 63
Synonyms: 4921511C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330188
Homologene: 45136
Tdpoz3
Name: TD and POZ domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 399674
Homologene: 128308
Klhl9
Name: kelch-like 9
Synonyms: C530050O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242521
Homologene: 23125
4921509C19Rik
Name: RIKEN cDNA 4921509C19 gene
Synonyms: LOC381389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381393
Homologene: 72396
Arhgap22
Name: Rho GTPase activating protein 22
Synonyms: RHOGAP2, B230341L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239027
Homologene: 23292
Tsga10
Name: testis specific 10
Synonyms: 4933432N21Rik, Mtsga10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 211484
Homologene: 23531
Mettl24
Name: methyltransferase like 24
Synonyms: 9030224M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327747
Homologene: 65335
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74918
Homologene: 49784
Olfr130
Name: olfactory receptor 130
Synonyms: GA_x6K02T2PSCP-2515350-2516303, MOR256-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258480
Homologene: 105876
Lca5l
Name: Leber congenital amaurosis 5-like
Synonyms: 4921526F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 385668
HGNC: HGNC:1255
Homologene: 47978
Olfr1008
Name: olfactory receptor 1008
Synonyms: GA_x6K02T2Q125-47170431-47171372, MOR187-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258866
4933412E24Rik
Name: RIKEN cDNA 4933412E24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71088
VEGA: 15
Homologene: 129990
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243944
Homologene: 77912
Klre1
Name: killer cell lectin-like receptor family E member 1
Synonyms: Klre-1, NKG2I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243655
Homologene: 17794
Slc10a5
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 5
Synonyms: LOC241877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241877
Homologene: 78106
Galntl6
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms: 4930431L04Rik, 1700021K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270049
Homologene: 65137
Cd55b
Name: CD55 molecule, decay accelerating factor for complement B
Synonyms: TM-DAF, complement-transmembrane, Daf-TM, Daf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13137
HGNC: HGNC:2665
Homologene: 479
Usp18
Name: ubiquitin specific peptidase 18
Synonyms: UBP43, 1110058H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 24110
Homologene: 8047
Sh2d4b
Name: SH2 domain containing 4B
Synonyms: A430109M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328381
Homologene: 19164
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 37,761,428 bp
  • T to A, chromosome 1 at 58,310,071 bp
  • G to A, chromosome 1 at 75,186,746 bp
  • T to C, chromosome 1 at 82,708,576 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • C to T, chromosome 1 at 128,193,596 bp
  • A to T, chromosome 1 at 130,414,076 bp
  • CGCTGGC to CGC, chromosome 1 at 153,221,646 bp
  • G to T, chromosome 1 at 153,221,700 bp
  • T to A, chromosome 2 at 29,980,063 bp
  • A to T, chromosome 2 at 85,689,446 bp
  • A to G, chromosome 2 at 120,693,439 bp
  • A to C, chromosome 2 at 151,472,766 bp
  • T to C, chromosome 3 at 10,334,424 bp
  • T to C, chromosome 3 at 88,898,096 bp
  • T to C, chromosome 3 at 90,458,721 bp
  • T to A, chromosome 3 at 93,826,881 bp
  • T to A, chromosome 3 at 107,926,986 bp
  • C to A, chromosome 3 at 142,541,557 bp
  • T to C, chromosome 4 at 46,165,193 bp
  • T to C, chromosome 4 at 88,721,737 bp
  • G to A, chromosome 4 at 98,756,519 bp
  • A to G, chromosome 4 at 132,378,420 bp
  • A to G, chromosome 4 at 150,615,372 bp
  • T to G, chromosome 5 at 122,110,946 bp
  • A to G, chromosome 6 at 94,663,914 bp
  • C to T, chromosome 6 at 112,477,177 bp
  • G to A, chromosome 6 at 121,261,493 bp
  • A to G, chromosome 6 at 129,582,415 bp
  • C to G, chromosome 7 at 19,087,270 bp
  • T to A, chromosome 7 at 29,009,697 bp
  • A to T, chromosome 7 at 40,993,056 bp
  • A to T, chromosome 7 at 120,360,985 bp
  • C to T, chromosome 8 at 23,180,911 bp
  • A to T, chromosome 8 at 45,241,494 bp
  • A to T, chromosome 8 at 58,911,340 bp
  • T to C, chromosome 8 at 85,062,029 bp
  • A to T, chromosome 9 at 75,335,651 bp
  • A to T, chromosome 9 at 76,491,295 bp
  • A to G, chromosome 10 at 40,810,619 bp
  • T to C, chromosome 11 at 16,862,964 bp
  • T to C, chromosome 11 at 115,882,454 bp
  • T to C, chromosome 12 at 31,535,619 bp
  • T to C, chromosome 13 at 59,717,804 bp
  • A to T, chromosome 13 at 67,139,863 bp
  • C to T, chromosome 14 at 33,367,113 bp
  • A to G, chromosome 14 at 40,874,182 bp
  • C to A, chromosome 14 at 101,794,269 bp
  • A to C, chromosome 14 at 103,184,835 bp
  • C to T, chromosome 15 at 39,025,678 bp
  • T to C, chromosome 15 at 60,015,311 bp
  • A to G, chromosome 15 at 64,754,862 bp
  • T to C, chromosome 16 at 96,161,360 bp
  • T to A, chromosome 17 at 38,067,923 bp
  • T to A, chromosome 18 at 21,088,729 bp
  • T to G, chromosome 18 at 22,019,041 bp
  • A to G, chromosome 19 at 4,329,191 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0961 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039090-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.