Strain Name:
C57BL/6J-MtgxR0962Btlr/Mmmh
Stock Number:
039091-MU
Citation ID:
RRID:MMRRC_039091-MU
Other Names:
R0962 (G1), C57BL/6J-MtgxR0962Btlr
Major Collection:

Gene Information

Ptprcap
Name: protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
Synonyms: CD-45-AP, LSM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19265
HGNC: HGNC:9667
Homologene: 48358
Cep57
Name: centrosomal protein 57
Synonyms: 4921510P06Rik, 3110002L15Rik, Tsp57, 4931428M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74360
Homologene: 8790
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227800
Homologene: 49301
Utp6
Name: UTP6 small subunit processome component
Synonyms: HCA66, 4732497O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216987
Homologene: 41265
Tex9
Name: testis expressed gene 9
Synonyms: tsec-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21778
Homologene: 32072
Brca1
Name: breast cancer 1, early onset
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12189
HGNC: HGNC:1100
Homologene: 5276
Stag1
Name: stromal antigen 1
Synonyms: SA-1, Scc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20842
Homologene: 21191
Agfg1
Name: ArfGAP with FG repeats 1
Synonyms: C130049H11Rik, Rip, Hrb, D730048C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15463
HGNC: HGNC:5175
Homologene: 37929
Mfn2
Name: mitofusin 2
Synonyms: hypertension related protein 1, D630023P19Rik, Fzo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 170731
Homologene: 8915
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, Emv66, par
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Htr1a
Name: 5-hydroxytryptamine (serotonin) receptor 1A
Synonyms: 5-HT1A receptor, Gpcr18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 15550
VEGA: 13
HGNC: HGNC:5286
Homologene: 20148
Dock7
Name: dedicator of cytokinesis 7
Synonyms: m, 3110056M06Rik, LOC242555
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67299
Homologene: 23566
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, LOC327983, Acac, A530025K05Rik, Acc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17207
Homologene: 11804
Ebf3
Name: early B cell factor 3
Synonyms: O/E-2, 3110018A08Rik, Olf-1/EBF-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13593
Homologene: 56472
Kirrel3
Name: kirre like nephrin family adhesion molecule 3
Synonyms: 1500010O20Rik, Neph2, 2900036G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67703
Homologene: 57050
Ms4a6c
Name: membrane-spanning 4-domains, subfamily A, member 6C
Synonyms: 2200009H22Rik, 2210417N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 73656
Homologene: 130765
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Arap1
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Synonyms: Centd2, 2410002L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69710
Homologene: 12326
Cachd1
Name: cache domain containing 1
Synonyms: B430218L07Rik, Vwcd1, 1190007F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320508
Homologene: 10854
Pcolce2
Name: procollagen C-endopeptidase enhancer 2
Synonyms: 2400001O18Rik, Pcpe2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 76477
HGNC: HGNC:8739
Homologene: 8357
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: Atp1al1, cHKA, HKalpha2, ATPase H+K+-transporting, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 192113
VEGA: 14
Homologene: 68197
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Birc1b, Naip-rs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mgr1, Mass1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110789
Homologene: 19815
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: A930015H12Rik, SPACR, IMP150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Kdm7a
Name: lysine (K)-specific demethylase 7A
Synonyms: ENSMUSG00000073143, A630082K20Rik, Kdm7a, Jhdm1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 338523
Homologene: 25281
Gucy2g
Name: guanylate cyclase 2g
Synonyms: GC-G, 2410077I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 73707
Homologene: 44544
Olfr869
Name: olfactory receptor 869
Synonyms: MOR145-6, GA_x6K02T2PVTD-13878275-13879204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258550
Homologene: 138312
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Olfr716
Name: olfactory receptor 716
Synonyms: MOR260-2, GA_x6K02T2PBJ9-9497411-9498355
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258597
Homologene: 121514
Micalcl
Name: MICAL C-terminal like
Synonyms: Ebitein1, 4921517J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100504195
Homologene: 13149
Hhipl1
Name: hedgehog interacting protein-like 1
Synonyms: 1600002O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 214305
VEGA: 12
Homologene: 81985
Adamtsl4
Name: ADAMTS-like 4
Synonyms: Tsrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229595
Homologene: 23141
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330222
Homologene: 27395
Ppfia3
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Synonyms: 2410127E16Rik, Liprin-alpha3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76787
HGNC: HGNC:9247
Homologene: 37833
Rpain
Name: RPA interacting protein
Synonyms: 2400006N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69723
Homologene: 13006
Ercc4
Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
Synonyms: Xpf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 50505
HGNC: HGNC:3436
Homologene: 3836
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241158
Homologene: 9561
Lgals3bp
Name: lectin, galactoside-binding, soluble, 3 binding protein
Synonyms: 90K, Tango10b, CyCAP, MAC-2BP, Ppicap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19039
HGNC: HGNC:6564
Homologene: 4067
P3h2
Name: prolyl 3-hydroxylase 2
Synonyms: Leprel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 210530
Homologene: 10062
Alkbh2
Name: alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
Synonyms: Abh2, mABH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231642
Homologene: 18393
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: 4931420H10Rik, Dip2, Kiaa0184-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 64451
Homologene: 41012
Iqca
Name: IQ motif containing with AAA domain
Synonyms: 4930585L22Rik, 4930465P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74918
Homologene: 49784
Hmbox1
Name: homeobox containing 1
Synonyms: F830020C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219150
Homologene: 11589
Htra3
Name: HtrA serine peptidase 3
Synonyms: 9530081K03Rik, 2210021K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 78558
Homologene: 12697
Olfr586
Name: olfactory receptor 586
Synonyms: MOR8-2, MOR8-7, GA_x6K02T2PBJ9-5836380-5835439
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259115
Homologene: 131143
Zbtb39
Name: zinc finger and BTB domain containing 39
Synonyms: 7030401O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 320080
VEGA: 10
Homologene: 8890
Pla2g4d
Name: phospholipase A2, group IVD
Synonyms: 2610311B01Rik, Pla2delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78390
Homologene: 52252
1700010H22Rik
Name: RIKEN cDNA 1700010H22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Lrp11
Name: low density lipoprotein receptor-related protein 11
Synonyms: 9830160H19Rik, 1700034J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237253
Homologene: 13133
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 14,898,163 bp
  • T to C, chromosome 1 at 82,886,396 bp
  • C to A, chromosome 1 at 90,142,731 bp
  • A to T, chromosome 1 at 92,899,568 bp
  • T to C, chromosome 2 at 37,560,469 bp
  • A to T, chromosome 2 at 76,950,156 bp
  • A to G, chromosome 2 at 120,280,617 bp
  • T to A, chromosome 3 at 95,684,488 bp
  • G to A, chromosome 4 at 98,945,195 bp
  • A to G, chromosome 4 at 100,983,301 bp
  • T to C, chromosome 4 at 147,882,201 bp
  • T to A, chromosome 5 at 35,668,356 bp
  • T to C, chromosome 5 at 98,566,561 bp
  • T to C, chromosome 5 at 114,123,953 bp
  • C to T, chromosome 5 at 142,161,875 bp
  • A to G, chromosome 6 at 39,147,194 bp
  • A to G, chromosome 7 at 45,347,722 bp
  • C to T, chromosome 7 at 101,384,914 bp
  • A to G, chromosome 7 at 103,122,010 bp
  • T to A, chromosome 7 at 107,148,087 bp
  • T to C, chromosome 7 at 112,380,417 bp
  • T to C, chromosome 7 at 137,225,203 bp
  • T to C, chromosome 8 at 13,001,964 bp
  • T to C, chromosome 8 at 45,033,326 bp
  • A to T, chromosome 9 at 13,808,743 bp
  • T to A, chromosome 9 at 20,137,538 bp
  • A to G, chromosome 9 at 35,000,997 bp
  • A to T, chromosome 9 at 54,446,412 bp
  • T to C, chromosome 9 at 72,484,092 bp
  • C to T, chromosome 9 at 80,381,741 bp
  • T to G, chromosome 9 at 95,670,034 bp
  • T to A, chromosome 9 at 100,796,827 bp
  • T to A, chromosome 10 at 7,590,296 bp
  • T to C, chromosome 10 at 76,292,432 bp
  • C to G, chromosome 10 at 127,742,306 bp
  • G to A, chromosome 11 at 70,975,041 bp
  • A to G, chromosome 11 at 79,941,868 bp
  • G to A, chromosome 11 at 84,311,303 bp
  • A to T, chromosome 11 at 101,525,366 bp
  • A to T, chromosome 11 at 118,393,020 bp
  • A to G, chromosome 12 at 7,989,191 bp
  • A to G, chromosome 12 at 108,327,721 bp
  • T to C, chromosome 13 at 81,405,346 bp
  • C to A, chromosome 13 at 100,179,385 bp
  • A to G, chromosome 13 at 105,444,324 bp
  • G to A, chromosome 14 at 56,368,413 bp
  • A to T, chromosome 14 at 64,896,774 bp
  • T to C, chromosome 16 at 13,130,146 bp
  • T to C, chromosome 16 at 25,997,248 bp
  • T to C, chromosome 18 at 67,405,427 bp
  • A to G, chromosome 19 at 4,156,464 bp
  • A to G, chromosome 19 at 9,012,848 bp
  • C to T, chromosome 19 at 11,471,142 bp
  • C to T, chromosome 19 at 55,210,284 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0962 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039091-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.