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Strain Name:
C57BL/6J-MtgxR1056Btlr/Mmmh
Stock Number:
039146-MU
Citation ID:
RRID:MMRRC_039146-MU
Other Names:
R1056 (G1), C57BL/6J-MtgxR1056Btlr
Major Collection:

Strain Information

Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: GENA 60, GENA 47, Gena 52, Cyn, A730019I05Rik, WBE1, Whi, Todo, Obt, Mt, Lda, Flo, Edy, Dz, Cycn
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Crhr2
Name: corticotropin releasing hormone receptor 2
Synonyms: Crfr2, CRF-R2, CRFR2beta, CRFR2alpha, CRF 2 receptor, CRH-R2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12922
HGNC: HGNC:2358
Homologene: 55612
Ulk2
Name: unc-51 like kinase 2
Synonyms: Unc51.2, A830085I22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 29869
Homologene: 5891
Rilpl1
Name: Rab interacting lysosomal protein-like 1
Synonyms: 6330559I19Rik, 2900002H16Rik, GOSPEL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75695
Homologene: 15619
Fgd4
Name: FYVE, RhoGEF and PH domain containing 4
Synonyms: Frabin-gamma, Frabin-beta, Frabin-alpha, Frabin, 9330209B17Rik, ZFYVE6
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224014
Homologene: 26727
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Ube2o
Name: ubiquitin-conjugating enzyme E2O
Synonyms: B230113M03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217342
Homologene: 11113
Dhx9
Name: DExH-box helicase 9
Synonyms: leukophysin, nuclear DNA helicase II, RNA helicase, Ddx9, NDH II, NDHII, RHA
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13211
HGNC: HGNC:2750
Homologene: 1039
Tasp1
Name: taspase, threonine aspartase 1
Synonyms: 4930485D02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75812
Homologene: 9795
Clasp2
Name: CLIP associating protein 2
Synonyms: 1500004F14Rik, CLASP2gamma, CLASP2beta, CLASP2alpha, CLASP2, 8030404L10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Nfx1
Name: nuclear transcription factor, X-box binding 1
Synonyms: TEG-42, 1300017N15Rik, 3000003M19Rik, Tex42
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74164
HGNC: HGNC:7803
Homologene: 1875
Rbbp4
Name: retinoblastoma binding protein 4, chromatin remodeling factor
Synonyms: CAF-1 p48 subunit, RBAP48
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19646
HGNC: HGNC:9887
Homologene: 21153
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Impact
Name: impact, RWD domain protein
Synonyms: E430016J11Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16210
VEGA: 18
Homologene: 5490
Dctn4
Name: dynactin 4
Synonyms: p62, 4930547K17Rik, 1110001K06Rik, C130039E17Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67665
VEGA: 18
Homologene: 9430
Cdc42bpg
Name: CDC42 binding protein kinase gamma
Synonyms: MRCKgamma
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240505
Homologene: 28384
Myo9a
Name: myosin IXa
Synonyms: 4732465J09Rik, C130068I12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 212377
Homologene: 18874
Ppil4
Name: peptidylprolyl isomerase (cyclophilin)-like 4
Synonyms: 3732410E19Rik, PPIase, 3830425H19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67418
Homologene: 12126
Zbtb14
Name: zinc finger and BTB domain containing 14
Synonyms: ZF5, Zfp161, b2b1982Clo
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22666
Homologene: 2560
Zfp951
Name: zinc finger protein 951
Synonyms: C230055K05Rik, Gm38611
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 626391
Homologene: 134630
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Midn
Name: midnolin
Synonyms: 3000003C15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59090
Homologene: 32510
Eif5b
Name: eukaryotic translation initiation factor 5B
Synonyms: IF2, A030003E17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226982
Homologene: 134613
Vmn1r206
Name: vomeronasal 1 receptor 206
Synonyms: V1rh7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171250
Homologene: 110880
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: FIC1, Ic
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Amfr
Name: autocrine motility factor receptor
Synonyms: gp78
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23802
HGNC: HGNC:463
Homologene: 888
Frmd4b
Name: FERM domain containing 4B
Synonyms: 6030440G05Rik, GRSP1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232288
Homologene: 14916
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Or52e3
Name: olfactory receptor family 52 subfamily E member 3
Synonyms: GA_x6K02T2PBJ9-5935234-5936169, MOR32-10, Olfr594
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258246
Homologene: 17480
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
C7
Name: complement component 7
Synonyms: LOC383055
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109828
VEGA: 15
HGNC: HGNC:1346
Homologene: 489
Ccdc168
Name: coiled-coil domain containing 168
Synonyms: Gm8251
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Ccdc180
Name: coiled-coil domain containing 180
Synonyms: LOC381522, E230008N13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381522
Homologene: 117988
Coq2
Name: coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
Synonyms: 2310002F18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71883
Homologene: 69192
Cgnl1
Name: cingulin-like 1
Synonyms: 4933421H10Rik, Jacop, 9930020M10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68178
Homologene: 41901
Chl1
Name: cell adhesion molecule L1-like
Synonyms: CALL, A530023M13Rik, close homolog of L1, LICAM2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Zfp747
Name: zinc finger protein 747
Synonyms: 6430604K15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269997
Homologene: 118005
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Mdga2, 9330209L04Rik, 6720489L24Rik, Mamdc1, Adp
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320772
Homologene: 45659
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: ojoplano, Opo
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218165
VEGA: 13
Homologene: 125376
Tnrc18
Name: trinucleotide repeat containing 18
Synonyms: EG381742, Zfp469
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231861
Homologene: 45603
Prob1
Name: proline rich basic protein 1
Synonyms: LOC381148, Gm1614
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 381148
Homologene: 83773
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Tas2r131
Name: taste receptor, type 2, member 131
Synonyms: mGR31, Tas2r31, mt2r61, T2R31
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387356
Homologene: 52298
Prdm13
Name: PR domain containing 13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230025
Homologene: 11000
Abcc10
Name: ATP-binding cassette, sub-family C member 10
Synonyms: Mrp7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Fbxw22
Name: F-box and WD-40 domain protein 22
Synonyms: Gm5164
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382156
Homologene: 110776
Sh3rf3
Name: SH3 domain containing ring finger 3
Synonyms: 4831416G18Rik, Sh3md4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237353
Homologene: 77551
Glra3
Name: glycine receptor, alpha 3 subunit
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110304
HGNC: HGNC:4328
Homologene: 142
Slc2a12
Name: solute carrier family 2 (facilitated glucose transporter), member 12
Synonyms: GLUT-12, Glut12
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 353169
Homologene: 59263
Aebp1
Name: AE binding protein 1
Synonyms: ACLP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11568
HGNC: HGNC:303
Homologene: 878
Sema6c
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Synonyms: Sema Y, Semay
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20360
Homologene: 7931
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213819
Homologene: 11287
Or1a1b
Name: olfactory receptor family 1 subfamily A member 1B
Synonyms: GA_x6K02T2P1NL-4359899-4358958, MOR125-1, Olfr43
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258706
Homologene: 8219
Lypd6b
Name: LY6/PLAUR domain containing 6B
Synonyms: 2310010M24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71897
Homologene: 12419
C230062I16Rik
Name: RIKEN cDNA C230062I16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 625421
Podnl1
Name: podocan-like 1
Synonyms: 5832418A03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244550
Homologene: 41590
Anks1b
Name: ankyrin repeat and sterile alpha motif domain containing 1B
Synonyms: LOC380650, C030032C09Rik, E530015N03Rik, AIDA-1b, Gm10937
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77531
Homologene: 51570
Ly6c2
Name: lymphocyte antigen 6 family memberC2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 100041546
Homologene: 113718
Bak1
Name: BCL2-antagonist/killer 1
Synonyms: N-Bak, Bak
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12018
HGNC: HGNC:949
Homologene: 917
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 38,022,167 bp
  • C to T, chromosome 1 at 44,060,927 bp
  • A to T, chromosome 1 at 153,468,967 bp
  • A to G, chromosome 2 at 32,288,202 bp
  • G to A, chromosome 2 at 49,947,456 bp
  • A to G, chromosome 2 at 140,008,764 bp
  • C to A, chromosome 3 at 36,983,453 bp
  • T to A, chromosome 3 at 37,044,680 bp
  • T to A, chromosome 3 at 38,891,392 bp
  • T to A, chromosome 3 at 95,171,216 bp
  • T to C, chromosome 4 at 8,822,402 bp
  • T to C, chromosome 4 at 11,192,707 bp
  • T to C, chromosome 4 at 21,678,544 bp
  • T to C, chromosome 4 at 24,586,344 bp
  • G to A, chromosome 4 at 41,003,057 bp
  • T to C, chromosome 4 at 45,916,375 bp
  • A to T, chromosome 4 at 129,317,649 bp
  • G to A, chromosome 4 at 137,511,829 bp
  • T to C, chromosome 4 at 143,438,011 bp
  • A to T, chromosome 5 at 14,540,055 bp
  • G to T, chromosome 5 at 100,657,947 bp
  • A to T, chromosome 5 at 104,815,285 bp
  • A to T, chromosome 5 at 124,493,837 bp
  • G to A, chromosome 5 at 142,773,859 bp
  • T to C, chromosome 6 at 4,641,967 bp
  • A to T, chromosome 6 at 55,100,735 bp
  • G to A, chromosome 6 at 97,412,484 bp
  • A to T, chromosome 6 at 103,675,077 bp
  • T to A, chromosome 6 at 132,957,067 bp
  • A to G, chromosome 7 at 29,953,648 bp
  • A to T, chromosome 7 at 103,220,418 bp
  • A to G, chromosome 7 at 120,325,072 bp
  • A to G, chromosome 7 at 127,374,588 bp
  • A to G, chromosome 8 at 41,321,900 bp
  • T to A, chromosome 8 at 56,085,104 bp
  • T to A, chromosome 8 at 84,129,276 bp
  • A to T, chromosome 8 at 93,985,469 bp
  • T to C, chromosome 9 at 7,147,731 bp
  • C to T, chromosome 9 at 59,832,201 bp
  • T to A, chromosome 9 at 71,725,895 bp
  • A to T, chromosome 9 at 109,378,916 bp
  • A to C, chromosome 9 at 113,911,626 bp
  • A to G, chromosome 10 at 7,799,632 bp
  • T to G, chromosome 10 at 22,665,451 bp
  • G to T, chromosome 10 at 59,007,082 bp
  • T to A, chromosome 10 at 80,151,471 bp
  • G to T, chromosome 10 at 90,921,429 bp
  • T to A, chromosome 11 at 5,865,378 bp
  • T to A, chromosome 11 at 61,801,571 bp
  • C to T, chromosome 11 at 74,206,782 bp
  • G to T, chromosome 11 at 116,546,464 bp
  • T to C, chromosome 12 at 66,723,120 bp
  • A to T, chromosome 13 at 22,620,614 bp
  • C to T, chromosome 13 at 40,208,829 bp
  • T to C, chromosome 15 at 5,045,778 bp
  • T to A, chromosome 15 at 44,591,964 bp
  • A to G, chromosome 15 at 75,111,596 bp
  • A to G, chromosome 16 at 16,475,166 bp
  • G to C, chromosome 16 at 22,600,541 bp
  • A to G, chromosome 17 at 27,021,273 bp
  • C to A, chromosome 17 at 33,583,987 bp
  • A to C, chromosome 17 at 46,303,954 bp
  • C to A, chromosome 17 at 69,388,502 bp
  • A to T, chromosome 18 at 12,976,524 bp
  • A to T, chromosome 18 at 35,653,610 bp
  • T to A, chromosome 18 at 60,552,963 bp
  • G to A, chromosome 18 at 64,573,477 bp
  • T to A, chromosome 19 at 6,314,021 bp
  • C to T, chromosome 19 at 10,223,486 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1056 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039146-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.