Strain Name:
C57BL/6J-MtgxR1201Btlr/Mmmh
Stock Number:
039271-MU
Citation ID:
RRID:MMRRC_039271-MU
Other Names:
R1201 (G1), C57BL/6J-MtgxR1201Btlr
Major Collection:

Gene Information

Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67937
Homologene: 8104
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco3, D10Wsu183e, Aco-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11429
HGNC: HGNC:118
Homologene: 856
Tlk2
Name: tousled-like kinase 2 (Arabidopsis)
Synonyms: PKUalpha, 4933403M19Rik, protein kinase U-alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 24086
Homologene: 4993
Acly
Name: ATP citrate lyase
Synonyms: A730098H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 104112
HGNC: HGNC:115
Homologene: 854
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Ccm2
Name: cerebral cavernous malformation 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216527
Homologene: 12868
Xdh
Name: xanthine dehydrogenase
Synonyms: xanthine oxidase, Xox-1, XO, Xox1, Xor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22436
VEGA: 17
Homologene: 324
Crh
Name: corticotropin releasing hormone
Synonyms: corticotropin releasing factor, CRF, corticotropin-releasing factor, LOC383938
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12918
HGNC: HGNC:2355
Homologene: 599
Dbf4
Name: DBF4 zinc finger
Synonyms: Ask
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 27214
Homologene: 40892
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: 2810036I15Rik, RIM2, Syt3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 116838
VEGA: 15
Homologene: 81639
Numb
Name: NUMB endocytic adaptor protein
Synonyms: m-numb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 18222
HGNC: HGNC:8060
Homologene: 2775
Fnbp1l
Name: formin binding protein 1-like
Synonyms: 2610318I01Rik, TOCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214459
Homologene: 134636
Ntn1
Name: netrin 1
Synonyms: Netrin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18208
HGNC: HGNC:8029
Homologene: 21008
Amph
Name: amphiphysin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218038
HGNC: HGNC:471
Homologene: 121585
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104806
VEGA: 12
Homologene: 35378
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217351
Homologene: 23137
Sh3bgrl2
Name: SH3 domain binding glutamic acid-rich protein like 2
Synonyms: A930014C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 212531
Homologene: 12876
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Zfp251
Name: zinc finger protein 251
Synonyms: 9130001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 71591
VEGA: 15
Homologene: 87789
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 1110061O17Rik, 9630046L06Rik, 9430004C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102075
Homologene: 18516
Prss45
Name: protease, serine 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 260408
Homologene: 51905
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242627
Homologene: 135888
Vmn1r76
Name: vomeronasal 1 receptor 76
Synonyms: V1rg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171239
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210045
Homologene: 65242
Zfp607a
Name: zinc finger protein 607A
Synonyms: 4732475C15Rik, Zfp607
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545938
Homologene: 134321
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: merg1a, merg1b, Lqt2, ether a go-go related, LQT, M-erg, ERG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Actc1
Name: actin, alpha, cardiac muscle 1
Synonyms: alphac-actin, Actc-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11464
HGNC: HGNC:143
Homologene: 68446
Olfr54
Name: olfactory receptor 54
Synonyms: MOR126-1, F3, GA_x6K02T2QP88-4411197-4410256
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18354
Homologene: 115479
Rab34
Name: RAB34, member RAS oncogene family
Synonyms: Rah1, Narr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19376
Homologene: 12908
Map1lc3b
Name: microtubule-associated protein 1 light chain 3 beta
Synonyms: Atg8, 1010001C15Rik, Map1lc3, LC3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67443
Homologene: 69359
Csgalnact2
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 2
Synonyms: Galnact2, 4632415D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78752
Homologene: 23109
Arhgap40
Name: Rho GTPase activating protein 40
Synonyms: Gm14203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545481
Homologene: 53500
4932414N04Rik
Name: RIKEN cDNA 4932414N04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75721
Homologene: 138468
Pidd1
Name: p53 induced death domain protein 1
Synonyms: Pidd, Lrdd, 1200011D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57913
Homologene: 11220
Catsperg1
Name: cation channel sperm associated auxiliary subunit gamma 1
Synonyms: Catsperg, A230107C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320225
Homologene: 10915
Otulinl
Name: OTU deubiquitinase with linear linkage specificity like
Synonyms: Fam105a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223433
VEGA: 15
Homologene: 41302
Krt36
Name: keratin 36
Synonyms: HRa-1, Krt1-22, Krt1-5, keratin 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Slc6a17
Name: solute carrier family 6 (neurotransmitter transporter), member 17
Synonyms: NTT4, D130012J15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229706
Homologene: 27775
Olfr727
Name: olfactory receptor 727
Synonyms: GA_x6K02T2PMLR-5817082-5818056, MOR246-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258316
Homologene: 84571
Prss33
Name: protease, serine 33
Synonyms: mT6, Eos, tryptase-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 353130
Homologene: 77185
Olfr1415
Name: olfactory receptor 1415
Synonyms: MOR103-12, GA_x6K02T2R7CC-81266841-81267776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258228
Homologene: 79367
Olfr175-ps1
Name: olfactory receptor 175, pseudogene 1
Synonyms: GA_x54KRFPKG5P-55026345-55025418, GA_x54KRFPKG5P-54993816-54992890, MOR184-10P, Olfr174, MOR184-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 259004
Homologene: 17461
Olfr1355
Name: olfactory receptor 1355
Synonyms: GA_x6K02T2QGN0-2932609-2931677, MOR139-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 257734
Homologene: 136441
Plekho1
Name: pleckstrin homology domain containing, family O member 1
Synonyms: Jza2, 2810052M02Rik, CKIP-1, JZA-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67220
Homologene: 9448
Car11
Name: carbonic anhydrase 11
Synonyms: CA-RP XI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12348
HGNC: HGNC:1370
Homologene: 36061
Zfp263
Name: zinc finger protein 263
Synonyms: mFPM315, 1200014J04Rik, NT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74120
Homologene: 4197
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 92,491,153 bp
  • A to G, chromosome 2 at 68,716,282 bp
  • A to G, chromosome 2 at 114,049,513 bp
  • A to C, chromosome 2 at 158,534,769 bp
  • A to G, chromosome 3 at 19,693,926 bp
  • A to G, chromosome 3 at 36,948,375 bp
  • G to A, chromosome 3 at 95,992,289 bp
  • T to A, chromosome 3 at 107,493,072 bp
  • A to G, chromosome 3 at 116,791,221 bp
  • T to C, chromosome 3 at 122,542,101 bp
  • A to G, chromosome 4 at 113,556,145 bp
  • A to C, chromosome 5 at 8,397,498 bp
  • C to T, chromosome 5 at 24,322,672 bp
  • A to G, chromosome 6 at 118,114,432 bp
  • G to T, chromosome 7 at 10,715,436 bp
  • A to C, chromosome 7 at 11,930,325 bp
  • T to A, chromosome 7 at 27,879,311 bp
  • A to T, chromosome 7 at 29,191,670 bp
  • A to G, chromosome 7 at 45,703,480 bp
  • A to G, chromosome 7 at 141,440,274 bp
  • C to T, chromosome 8 at 70,484,387 bp
  • A to G, chromosome 8 at 105,381,673 bp
  • T to C, chromosome 8 at 110,569,855 bp
  • T to C, chromosome 8 at 121,595,975 bp
  • C to T, chromosome 9 at 83,577,631 bp
  • T to A, chromosome 9 at 110,838,583 bp
  • A to T, chromosome 10 at 78,879,477 bp
  • T to C, chromosome 11 at 6,593,682 bp
  • T to A, chromosome 11 at 51,027,110 bp
  • T to C, chromosome 11 at 68,213,226 bp
  • T to A, chromosome 11 at 78,190,396 bp
  • T to C, chromosome 11 at 100,104,057 bp
  • A to G, chromosome 11 at 100,493,935 bp
  • T to C, chromosome 11 at 105,241,675 bp
  • T to G, chromosome 11 at 117,721,674 bp
  • A to G, chromosome 12 at 65,106,768 bp
  • A to T, chromosome 12 at 83,801,285 bp
  • G to A, chromosome 13 at 19,142,028 bp
  • T to A, chromosome 14 at 50,127,356 bp
  • G to A, chromosome 15 at 27,658,173 bp
  • A to C, chromosome 15 at 39,616,324 bp
  • C to T, chromosome 15 at 76,854,236 bp
  • C to T, chromosome 15 at 81,895,193 bp
  • T to A, chromosome 16 at 3,749,430 bp
  • A to G, chromosome 16 at 58,823,863 bp
  • G to T, chromosome 17 at 23,835,110 bp
  • T to C, chromosome 17 at 73,918,418 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1201 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039271-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.