Strain Name:
C57BL/6J-MtgxR1210Btlr/Mmmh
Stock Number:
039279-MU
Citation ID:
RRID:MMRRC_039279-MU
Other Names:
R1210 (G1), C57BL/6J-MtgxR1210Btlr
Major Collection:

Gene Information

Cwf19l2
Name: CWF19-like 2, cell cycle control (S. pombe)
Synonyms: 3230401L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244672
Homologene: 12366
Itga5
Name: integrin alpha 5 (fibronectin receptor alpha)
Synonyms: Fnra, Cd49e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16402
VEGA: 15
HGNC: HGNC:6141
Homologene: 20508
Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: nuclear factor kappaB p50, NF-kappaB p50, NF-kappaB, p50/p105, p50 subunit of NF kappaB, NF kappaB1, p50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18033
HGNC: HGNC:7794
Homologene: 2971
Rock2
Name: Rho-associated coiled-coil containing protein kinase 2
Synonyms: Rock2m, B230113H15Rik, Rho-kinase, Rock-II, ROKalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19878
VEGA: 12
Homologene: 21010
Eef1b2
Name: eukaryotic translation elongation factor 1 beta 2
Synonyms: 2810017J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 55949
HGNC: HGNC:3208
Homologene: 1480
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, 9930018I23Rik, Loa, Dnec1, Dnchc1, dynein heavy chain, retrograde transport, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Lrrfip1
Name: leucine rich repeat (in FLII) interacting protein 1
Synonyms: Fliiap1, FLAP (FLI LRR associated protein)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16978
HGNC: HGNC:6702
Homologene: 48301
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: 8430415E05Rik, 1700034M03Rik, Ccdc132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73288
Homologene: 11498
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: Facl5, 1700030F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Clec7a
Name: C-type lectin domain family 7, member a
Synonyms: dectin-1, beta-glucan receptor, beta-GR, BGR, Clecsf12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56644
Homologene: 49606
Mme
Name: membrane metallo endopeptidase
Synonyms: CD10, 6030454K05Rik, NEP, neprilysin, neutral endopeptidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17380
HGNC: HGNC:7154
Homologene: 5275
Olfr720
Name: olfactory receptor 720
Synonyms: MOR274-2, GA_x6K02T2PLTE-6544896-6543946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258387
Homologene: 74036
Gm5422
Name: predicted pseudogene 5422
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432448
VEGA: 10
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: Epcs21, GlcT-1, Ugcgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22234
Homologene: 37763
Olfr1186
Name: olfactory receptor 1186
Synonyms: GA_x6K02T2Q125-50012960-50013871, MOR230-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258523
Homologene: 110555
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930449A08Rik, 4930538D17Rik, Tmem180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 75146
Homologene: 12592
Fam83a
Name: family with sequence similarity 83, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239463
Homologene: 13158
Vmn2r89
Name: vomeronasal 2, receptor 89
Synonyms: V2r11, V2r10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 22301
Cdh15
Name: cadherin 15
Synonyms: Mcad, Cdh14, M cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: LOC384387, C330043M08Rik, Fam188b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330323
Homologene: 49991
Sav1
Name: salvador family WW domain containing 1
Synonyms: 1700040G09Rik, WW45, Salv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 64010
VEGA: 12
Homologene: 32517
Olfr38
Name: olfactory receptor 38
Synonyms: 18A, GA_x6K02T2P3E9-4797841-4796888, MOR257-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258988
HGNC: HGNC:8246
Homologene: 72050
Csf3
Name: colony stimulating factor 3 (granulocyte)
Synonyms: MGI-IG, G-CSF, Csfg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12985
HGNC: HGNC:2438
Homologene: 7677
Olfr172
Name: olfactory receptor 172
Synonyms: GA_x54KRFPKG5P-54930346-54929417, MOR184-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259003
HGNC: HGNC:8349
Homologene: 45084
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 63,177,273 bp
  • A to G, chromosome 1 at 91,115,193 bp
  • G to C, chromosome 2 at 88,526,276 bp
  • A to G, chromosome 3 at 63,343,606 bp
  • A to G, chromosome 3 at 135,594,927 bp
  • C to T, chromosome 4 at 59,207,798 bp
  • G to A, chromosome 6 at 3,594,884 bp
  • T to C, chromosome 6 at 42,762,667 bp
  • T to A, chromosome 6 at 55,284,813 bp
  • T to C, chromosome 6 at 129,465,525 bp
  • G to C, chromosome 8 at 122,857,495 bp
  • T to C, chromosome 9 at 3,430,810 bp
  • A to G, chromosome 10 at 31,250,723 bp
  • A to G, chromosome 11 at 98,702,477 bp
  • T to A, chromosome 12 at 16,965,469 bp
  • A to G, chromosome 12 at 69,969,179 bp
  • A to G, chromosome 12 at 110,616,692 bp
  • T to C, chromosome 14 at 14,176,029 bp
  • T to C, chromosome 14 at 51,454,970 bp
  • A to T, chromosome 15 at 57,995,248 bp
  • A to G, chromosome 15 at 103,357,473 bp
  • T to C, chromosome 16 at 58,761,050 bp
  • C to T, chromosome 19 at 46,366,504 bp
  • C to A, chromosome 19 at 55,293,577 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1210 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039279-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.