Strain Name:
C57BL/6J-MtgxR1299Btlr/Mmmh
Stock Number:
039365-MU
Citation ID:
RRID:MMRRC_039365-MU
Other Names:
R1299 (G1), C57BL/6J-MtgxR1299Btlr
Major Collection:

Gene Information

Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: Ctrn, citrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 50799
Homologene: 22800
Fam133b
Name: family with sequence similarity 133, member B
Synonyms: 2900022K02Rik, 5830415L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68152
Homologene: 85443
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, D14Ertd453e, Fndc3, sys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319448
Homologene: 8952
Cdc73
Name: cell division cycle 73, Paf1/RNA polymerase II complex component
Synonyms: C130030P16Rik, 8430414L16Rik, Hrpt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214498
Homologene: 11571
Parn
Name: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN, 1200003I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 74108
VEGA: 16
HGNC: HGNC:8609
Homologene: 31098
Ate1
Name: arginyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11907
HGNC: HGNC:782
Homologene: 31420
Golga3
Name: golgi autoantigen, golgin subfamily a, 3
Synonyms: Mea-2, Mea2, 5430416E01Rik, G1-499-14, repro27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269682
HGNC: HGNC:4426
Homologene: 4308
Prox1
Name: prospero homeobox 1
Synonyms: A230003G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19130
HGNC: HGNC:9459
Homologene: 2069
Gramd1c
Name: GRAM domain containing 1C
Synonyms: 4921521N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207798
Homologene: 129735
Tgfbr1
Name: transforming growth factor, beta receptor I
Synonyms: TbetaR-I, TbetaRI, ALK5, Alk-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21812
Homologene: 3177
Katnip
Name: katanin interacting protein
Synonyms: D430042O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233865
Homologene: 45841
Smarcc2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Synonyms: 5930405J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 68094
VEGA: 10
Homologene: 2312
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Xpr1
Name: xenotropic and polytropic retrovirus receptor 1
Synonyms: suppressor of yeast Ga deletion, Syg1, Rmc-1, Rmc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19775
Homologene: 134226
Gpr142
Name: G protein-coupled receptor 142
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217302
Homologene: 18770
Cgnl1
Name: cingulin-like 1
Synonyms: Jacop, 4933421H10Rik, 9930020M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68178
Homologene: 41901
Gypa
Name: glycophorin A
Synonyms: CD235a, GPA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14934
Pcdhb22
Name: protocadherin beta 22
Synonyms: Pcdhb15, PcdhbV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93893
HGNC: HGNC:8686
Homologene: 113752
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: Jnkbp1, 2810483F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26390
Homologene: 69109
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: brm, Snf2l2, 2610209L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67155
Homologene: 2308
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277360
Homologene: 10821
Zfp882
Name: zinc finger protein 882
Synonyms: ENSMUSG00000052439
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382019
Homologene: 136303
Prss55
Name: protease, serine 55
Synonyms: 4933401F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71037
Homologene: 51233
Tdpoz4
Name: TD and POZ domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 399675
Homologene: 130121
Acnat1
Name: acyl-coenzyme A amino acid N-acyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230161
Homologene: 28287
Or5b104
Name: olfactory receptor family 5 subfamily B member 104
Synonyms: GA_x6K02T2RE5P-3423041-3422097, MOR202-20, Olfr1457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258568
HGNC: HGNC:8324
Homologene: 133676
H2-DMb2
Name: histocompatibility 2, class II, locus Mb2
Synonyms: H2-Mb2, H-2Mb2, H2-M beta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15000
HGNC: HGNC:4935
Homologene: 68231
Klhl17
Name: kelch-like 17
Synonyms: actinfilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 231003
VEGA: 4
Homologene: 27075
Or6c217
Name: olfactory receptor family 6 subfamily C member 217
Synonyms: GA_x6K02T2PULF-11581263-11580331, MOR113-3, Olfr815
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258665
Cbx8
Name: chromobox 8
Synonyms: polycomb 3, Pc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 30951
Homologene: 32199
AC120404.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Zfp354b
Name: zinc finger protein 354B
Synonyms: Kid2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27274
Homologene: 32187
Mblac2
Name: metallo-beta-lactamase domain containing 2
Synonyms: 2900024O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72852
VEGA: 13
Homologene: 15174
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 143,699,281 bp
  • A to C, chromosome 1 at 155,417,203 bp
  • G to T, chromosome 1 at 190,146,943 bp
  • G to A, chromosome 2 at 120,015,404 bp
  • A to G, chromosome 2 at 166,585,907 bp
  • A to T, chromosome 3 at 93,796,462 bp
  • T to A, chromosome 4 at 47,396,587 bp
  • T to A, chromosome 4 at 49,450,925 bp
  • G to A, chromosome 4 at 63,265,631 bp
  • T to C, chromosome 4 at 156,230,962 bp
  • T to C, chromosome 5 at 3,554,626 bp
  • G to A, chromosome 5 at 110,204,843 bp
  • C to T, chromosome 6 at 6,113,937 bp
  • T to C, chromosome 6 at 68,704,498 bp
  • A to C, chromosome 7 at 125,852,023 bp
  • A to T, chromosome 7 at 130,504,755 bp
  • A to G, chromosome 8 at 71,913,473 bp
  • G to A, chromosome 8 at 80,496,753 bp
  • G to A, chromosome 9 at 71,721,712 bp
  • C to A, chromosome 10 at 128,461,378 bp
  • A to G, chromosome 10 at 129,902,077 bp
  • T to C, chromosome 11 at 9,294,821 bp
  • A to C, chromosome 11 at 50,923,470 bp
  • A to T, chromosome 11 at 114,804,359 bp
  • T to C, chromosome 11 at 119,040,850 bp
  • C to A, chromosome 13 at 81,711,726 bp
  • A to T, chromosome 14 at 64,081,698 bp
  • A to G, chromosome 14 at 68,526,299 bp
  • A to G, chromosome 14 at 72,566,198 bp
  • G to A, chromosome 16 at 13,664,729 bp
  • A to G, chromosome 16 at 43,983,502 bp
  • T to C, chromosome 17 at 34,150,587 bp
  • T to C, chromosome 18 at 37,520,590 bp
  • T to C, chromosome 19 at 5,745,428 bp
  • T to A, chromosome 19 at 13,095,130 bp
  • T to C, chromosome 19 at 26,771,611 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1299 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039365-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.