Strain Name:
C57BL/6J-MtgxR1301Btlr/Mmmh
Stock Number:
039367-MU
Citation ID:
RRID:MMRRC_039367-MU
Other Names:
R1301 (G1), C57BL/6J-MtgxR1301Btlr
Major Collection:

Gene Information

Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22427
Homologene: 6659
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: Aclp7, Acf7, trabeculin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11426
Homologene: 136191
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, b2b1625.2Clo, Gp330, Megalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: D10Ertd398e, 4.1G, Epb4.1l2, NBL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Ano1
Name: anoctamin 1, calcium activated chloride channel
Synonyms: Tmem16a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101772
Homologene: 75079
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR, Red
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Nup133
Name: nucleoporin 133
Synonyms: 4832420O05Rik, mermaid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234865
Homologene: 32402
Phc1
Name: polyhomeotic 1
Synonyms: Mph1, rae28, Edr1, Rae-28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13619
HGNC: HGNC:3182
Homologene: 107079
Klhl7
Name: kelch-like 7
Synonyms: Klhl6, D5Ertd363e, 2700038B03Rik, SBBI26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52323
Homologene: 10317
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: Dcdc2, RU2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 195208
Homologene: 9483
Plpp1
Name: phospholipid phosphatase 1
Synonyms: Ppap2a, Hpic53, mPAP, LPP-1, LPP1, Lipid phosphate phosphatase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19012
VEGA: 13
HGNC: HGNC:9228
Homologene: 134049
Mta2
Name: metastasis-associated gene family, member 2
Synonyms: Mta1l1, mmta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 23942
HGNC: HGNC:7411
Homologene: 3480
Chd1l
Name: chromodomain helicase DNA binding protein 1-like
Synonyms: 4432404A22Rik, Snf2p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68058
HGNC: HGNC:1916
Homologene: 11590
Golm1
Name: golgi membrane protein 1
Synonyms: D030064E01Rik, GP73, 2310001L02Rik, Golph2, PSEC0257
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105348
VEGA: 13
Homologene: 12346
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239102
Homologene: 52657
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: RdgB, DRES9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Tatdn2
Name: TatD DNase domain containing 2
Synonyms: mKIAA0218
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 381801
Homologene: 8848
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: Gm1027, LOC381538, Heatr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381538
Homologene: 19633
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Camta2
Name: calmodulin binding transcription activator 2
Synonyms: Kiaa0909-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216874
Homologene: 9021
Gpn1
Name: GPN-loop GTPase 1
Synonyms: 2410004J02Rik, Xab1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74254
Homologene: 5257
Myo3a
Name: myosin IIIA
Synonyms: 9030416P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 667663
HGNC: HGNC:7601
Homologene: 49486
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: FOAP-10, basilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 246707
VEGA: 17
Homologene: 36483
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, LTRPC1, melastatin, 4732499L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69983
Homologene: 37424
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 242274
Homologene: 10817
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20957
Homologene: 2389
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: mG145, Rp1h, oxygen-regulated protein 1, Orp1, Dcdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19888
Homologene: 4564
4921528O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Olfr1338
Name: olfactory receptor 1338
Synonyms: MOR259-4P, Olfr1524-ps1, MOR259-9, GA_x6K02T2QD9B-18795136-18796077, MOR259-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258259
Homologene: 115537
Fbxo47
Name: F-box protein 47
Synonyms: LOC380724, 2900052P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72973
Homologene: 47677
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53419
Homologene: 4804
Gm13124
Name: predicted gene 13124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 627085
Homologene: 135767
Serpinb1c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1c
Synonyms: EIC, ovalbumin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 380839
HGNC: HGNC:3311
Homologene: 137840
Nup210
Name: nucleoporin 210
Synonyms: gp210, gp190, Pom210
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54563
Homologene: 41286
Speg
Name: SPEG complex locus
Synonyms: Apeg1, SPEGalpha, SPEG, BPEG, SPEGbeta, D1Bwg1450e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11790
Homologene: 55619
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: Gprc1h, mGluR8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Slc26a4
Name: solute carrier family 26, member 4
Synonyms: pendrin, Pds
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 23985
VEGA: 12
HGNC: HGNC:8818
Homologene: 20132
Olfr1499
Name: olfactory receptor 1499
Synonyms: GA_x6K02T2RE5P-4147744-4146800, MOR211-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258792
Homologene: 17393
Parl
Name: presenilin associated, rhomboid-like
Synonyms: D16Ertd607e, PSARL1, Psarl, PRO2207, PSENIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 381038
Homologene: 10239
Tmem67
Name: transmembrane protein 67
Synonyms: 5330408M12Rik, b2b1163.1Clo, b2b1291.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329795
Homologene: 71886
Hsd17b7
Name: hydroxysteroid (17-beta) dehydrogenase 7
Synonyms: ERG27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 15490
HGNC: HGNC:5215
Homologene: 40728
Zfp819
Name: zinc finger protein 819
Synonyms: 4930427I11Rik, 4933405K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74400
Homologene: 128446
Slc37a2
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 2
Synonyms: G3PP, cI-2, ci2, Slc37a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56857
Homologene: 41357
Gm4450
Name: predicted gene 4450
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100043461
Homologene: 104115
Gsdmd
Name: gasdermin D
Synonyms: 1810036L03Rik, DF5L, M2-4, Gsdmdc1, Dfna5l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69146
VEGA: 15
Homologene: 12299
Olfr1466
Name: olfactory receptor 1466
Synonyms: MOR202-12, GA_x6K02T2RE5P-3672907-3673839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258689
Homologene: 133677
Catsperz
Name: cation channel sperm associated auxiliary subunit zeta
Synonyms: 1700019N12Rik, Tex40, A430107B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67077
VEGA: 19
Homologene: 85555
Pacc1
Name: proton activated chloride channel 1
Synonyms: Tmem206, 2310028N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66950
Homologene: 10097
Cyb5rl
Name: cytochrome b5 reductase-like
Synonyms: 2810410C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230582
Homologene: 45506
Paqr7
Name: progestin and adipoQ receptor family member VII
Synonyms: mPR, Mpra, PGLP, 2310021M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 71904
Homologene: 12420
Nrip2
Name: nuclear receptor interacting protein 2
Synonyms: NIX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 60345
Homologene: 11023
Slc16a9
Name: solute carrier family 16 (monocarboxylic acid transporters), member 9
Synonyms: 4930425B13Rik, 1200003C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66859
Homologene: 32642
Pxdc1
Name: PX domain containing 1
Synonyms: 1300014I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66895
Homologene: 12051
Gpr84
Name: G protein-coupled receptor 84
Synonyms: EX33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 80910
VEGA: 15
HGNC: HGNC:4535
Homologene: 41370
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 4,345,936 bp
  • T to A, chromosome 1 at 75,401,501 bp
  • C to T, chromosome 1 at 163,043,983 bp
  • T to A, chromosome 1 at 169,961,205 bp
  • T to C, chromosome 1 at 191,348,435 bp
  • A to T, chromosome 2 at 22,267,095 bp
  • C to A, chromosome 2 at 69,428,604 bp
  • T to C, chromosome 3 at 72,946,582 bp
  • T to C, chromosome 3 at 97,603,648 bp
  • G to A, chromosome 3 at 98,446,866 bp
  • T to C, chromosome 3 at 102,920,622 bp
  • T to C, chromosome 3 at 158,135,331 bp
  • T to C, chromosome 4 at 12,089,400 bp
  • T to C, chromosome 4 at 106,720,495 bp
  • T to G, chromosome 4 at 107,080,907 bp
  • C to T, chromosome 4 at 118,753,619 bp
  • T to C, chromosome 4 at 123,486,658 bp
  • T to C, chromosome 4 at 134,507,813 bp
  • T to A, chromosome 4 at 144,565,065 bp
  • T to G, chromosome 5 at 24,159,491 bp
  • T to A, chromosome 5 at 31,503,429 bp
  • C to A, chromosome 5 at 72,304,933 bp
  • G to T, chromosome 6 at 27,981,201 bp
  • A to G, chromosome 6 at 73,208,545 bp
  • C to T, chromosome 6 at 91,042,347 bp
  • T to A, chromosome 6 at 113,704,115 bp
  • A to G, chromosome 6 at 122,325,874 bp
  • A to G, chromosome 6 at 128,407,389 bp
  • T to A, chromosome 7 at 43,617,100 bp
  • C to T, chromosome 7 at 46,289,689 bp
  • T to A, chromosome 7 at 64,203,053 bp
  • T to A, chromosome 7 at 80,455,417 bp
  • A to G, chromosome 7 at 144,633,689 bp
  • T to C, chromosome 8 at 33,292,686 bp
  • T to C, chromosome 8 at 123,917,417 bp
  • A to G, chromosome 9 at 37,236,881 bp
  • T to A, chromosome 10 at 25,443,902 bp
  • A to G, chromosome 10 at 70,282,478 bp
  • A to G, chromosome 11 at 70,676,404 bp
  • C to T, chromosome 11 at 97,868,601 bp
  • A to T, chromosome 12 at 31,525,568 bp
  • A to T, chromosome 13 at 25,102,586 bp
  • T to A, chromosome 13 at 32,896,960 bp
  • A to G, chromosome 13 at 34,628,887 bp
  • T to C, chromosome 13 at 59,638,373 bp
  • G to A, chromosome 13 at 96,659,020 bp
  • A to G, chromosome 13 at 112,834,943 bp
  • A to G, chromosome 14 at 55,063,397 bp
  • C to A, chromosome 15 at 75,867,059 bp
  • T to A, chromosome 15 at 103,309,219 bp
  • A to G, chromosome 16 at 20,286,926 bp
  • T to C, chromosome 17 at 71,255,965 bp
  • T to G, chromosome 19 at 4,110,831 bp
  • G to A, chromosome 19 at 6,925,082 bp
  • A to G, chromosome 19 at 8,949,186 bp
  • A to T, chromosome 19 at 13,341,847 bp
  • A to T, chromosome 19 at 13,815,362 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1301 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039367-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.