Strain Name:
C57BL/6J-MtgxR1364Btlr/Mmmh
Stock Number:
039429-MU
Citation ID:
RRID:MMRRC_039429-MU
Other Names:
R1364 (G1), C57BL/6J-MtgxR1364Btlr
Major Collection:

Gene Information

Prkd3
Name: protein kinase D3
Synonyms: 5730497N19Rik, PKD3, 4930557O20Rik, Prkcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75292
HGNC: HGNC:9408
Homologene: 2055
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20564
Homologene: 2303
Mid1
Name: midline 1
Synonyms: 61B3-R, Fxy, Trim18, DXHXS1141
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 17318
HGNC: HGNC:7095
Homologene: 7837
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Fnbp1
Name: formin binding protein 1
Synonyms: 2210010H06Rik, FBP1, 1110057E06Rik, FBP17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14269
Homologene: 100983
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Otud7b
Name: OTU domain containing 7B
Synonyms: 2900060B22Rik, 4930463P07Rik, Za20d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229603
Homologene: 10624
Ahi1
Name: Abelson helper integration site 1
Synonyms: 1700015F03Rik, Ahi-1, Jouberin, D10Bwg0629e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52906
VEGA: 10
Homologene: 9762
Hjurp
Name: Holliday junction recognition protein
Synonyms: A730008H23Rik, C330011F01Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381280
Homologene: 10184
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20743
VEGA: 19
Homologene: 48482
Wdr75
Name: WD repeat domain 75
Synonyms: 2410118I19Rik, 1300003A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 73674
Homologene: 32771
Unkl
Name: unkempt family like zinc finger
Synonyms: 1300004G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74154
Homologene: 62673
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234839
Homologene: 124356
Csn1s1
Name: casein alpha s1
Synonyms: Csna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12990
HGNC: HGNC:2445
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241589
Homologene: 115928
Mfsd13a
Name: major facilitator superfamily domain containing 13a
Synonyms: 4930538D17Rik, Tmem180, 4930449A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 75146
Homologene: 12592
Nebl
Name: nebulette
Synonyms: A630080F05Rik, 1200007O21Rik, Lnebl, D830029A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74103
Homologene: 128431
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: slo2, C030030G16Rik, Slack
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227632
Homologene: 11055
Fam126a
Name: family with sequence similarity 126, member A
Synonyms: hyccin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 84652
Homologene: 57175
Olfr1491
Name: olfactory receptor 1491
Synonyms: MOR266-8, GA_x6K02T2RE5P-4037809-4038768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258342
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17836
Homologene: 136663
Sgsm3
Name: small G protein signaling modulator 3
Synonyms: Rutbc3, 1810012I01Rik, CIP85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105835
Homologene: 9249
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 24087
VEGA: 19
Homologene: 56545
Ripk3
Name: receptor-interacting serine-threonine kinase 3
Synonyms: 2610528K09Rik, Rip3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56532
VEGA: 14
Homologene: 31410
Cobll1
Name: Cobl-like 1
Synonyms: Coblr1, D430044D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 319876
Homologene: 8933
Rasl10b
Name: RAS-like, family 10, member B
Synonyms: VTS58635, B230331P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276952
Homologene: 14108
Prl3b1
Name: prolactin family 3, subfamily b, member 1
Synonyms: Pl2, prolactin-like, mPL-II, mplII, PL, Csh2, Pl-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18776
Homologene: 7476
Gm17661
Name: predicted gene, 17661
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 45,799,062 bp
  • T to TN, chromosome 1 at 88,266,525 bp
  • A to T, chromosome 2 at 17,393,037 bp
  • A to G, chromosome 2 at 25,908,094 bp
  • T to C, chromosome 2 at 31,059,031 bp
  • A to G, chromosome 2 at 65,126,310 bp
  • GA to GAA, chromosome 2 at 90,917,709 bp
  • A to T, chromosome 2 at 104,155,018 bp
  • T to C, chromosome 3 at 36,987,030 bp
  • A to G, chromosome 3 at 96,151,451 bp
  • T to C, chromosome 5 at 23,965,353 bp
  • T to C, chromosome 5 at 87,677,584 bp
  • T to A, chromosome 6 at 121,881,713 bp
  • T to C, chromosome 8 at 122,498,571 bp
  • G to A, chromosome 8 at 123,304,281 bp
  • T to A, chromosome 9 at 66,400,093 bp
  • T to A, chromosome 10 at 20,972,156 bp
  • G to A, chromosome 11 at 35,670,107 bp
  • G to A, chromosome 11 at 83,417,839 bp
  • T to A, chromosome 11 at 118,125,606 bp
  • G to A, chromosome 13 at 27,243,865 bp
  • A to C, chromosome 14 at 55,785,260 bp
  • T to C, chromosome 15 at 81,007,942 bp
  • A to G, chromosome 17 at 25,189,623 bp
  • T to C, chromosome 17 at 78,957,258 bp
  • T to C, chromosome 19 at 4,732,665 bp
  • T to C, chromosome 19 at 13,705,445 bp
  • G to A, chromosome 19 at 41,120,228 bp
  • C to T, chromosome 19 at 46,366,504 bp
  • A to C, chromosome X at 169,986,094 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1364 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039429-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.