Strain Name:
C57BL/6J-MtgxR1389Btlr/Mmmh
Stock Number:
039451-MU
Citation ID:
RRID:MMRRC_039451-MU
Other Names:
R1389 (G1), C57BL/6J-MtgxR1389Btlr
Major Collection:

Gene Information

Dst
Name: dystonin
Synonyms: A830042E19Rik, 2310001O04Rik, Macf2, bullous pemphigoid antigen 1, BPAG1-n, BPAG1, athetoid, Bpag, ah, bullous pemphigoid antigen 1, Bpag1, nmf339, nmf203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Btbd11
Name: BTB (POZ) domain containing 11
Synonyms: 6330404E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74007
Homologene: 72536
Vipr2
Name: vasoactive intestinal peptide receptor 2
Synonyms: Vip2, VPAC2R, VPAC2, VIP receptor subtype 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22355
Homologene: 2540
Exog
Name: endo/exonuclease (5'-3'), endonuclease G-like
Synonyms: Endogl1, ENDOGL2, ENGL-a, ENGL-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208194
VEGA: 9
HGNC: HGNC:3347
Homologene: 3745
Pkn2
Name: protein kinase N2
Synonyms: Stk7, 6030436C20Rik, Prkcl2, PRK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Zc3h11a
Name: zinc finger CCCH type containing 11A
Synonyms: 1110003F06Rik, G630041M05Rik, 5730454B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70579
Homologene: 8888
Dcaf8
Name: DDB1 and CUL4 associated factor 8
Synonyms: D1Dau35e, D1Ucla4, Wdr42a, H326
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98193
Homologene: 56725
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: Dbc1, 2610301G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219158
VEGA: 14
Homologene: 10910
Senp1
Name: SUMO1/sentrin specific peptidase 1
Synonyms: 2310046A20Rik, E330036L07Rik, D15Ertd528e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223870
Homologene: 8731
Mapk1ip1
Name: mitogen-activated protein kinase 1 interacting protein 1
Synonyms: Miss, 2310009E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69546
Homologene: 75251
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212377
Homologene: 18874
Tmem123
Name: transmembrane protein 123
Synonyms: 2310075C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71929
Homologene: 14177
Arhgef17
Name: Rho guanine nucleotide exchange factor (GEF) 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 207212
Homologene: 129601
Zranb1
Name: zinc finger, RAN-binding domain containing 1
Synonyms: 9330160G10Rik, D7Wsu87e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 360216
Homologene: 9728
Tap2
Name: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: Ham2, PSF2, Abcb3, Ham-2, MTP2, HAM2, Tap-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21355
HGNC: HGNC:44
Homologene: 37323
Car9
Name: carbonic anhydrase 9
Synonyms: MN/CA9, CAIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230099
HGNC: HGNC:1383
Homologene: 20325
Gramd1c
Name: GRAM domain containing 1C
Synonyms: 4921521N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207798
Homologene: 129735
Rnf13
Name: ring finger protein 13
Synonyms: Rzf, 2010001H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 24017
Homologene: 13493
Ddah1
Name: dimethylarginine dimethylaminohydrolase 1
Synonyms: 2410006N07Rik, 2510015N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69219
HGNC: HGNC:2715
Homologene: 8120
Acsl3
Name: acyl-CoA synthetase long-chain family member 3
Synonyms: Facl3, 2610510B12Rik, C85929
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74205
HGNC: HGNC:3570
Homologene: 3278
Paf1
Name: Paf1, RNA polymerase II complex component
Synonyms: 5730511K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54624
Homologene: 5441
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Bpifb1
Name: BPI fold containing family B, member 1
Synonyms: von Ebner minor salivary protein, U46068, LPlunc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228801
Homologene: 50047
Krt19
Name: keratin 19
Synonyms: cytokeratin19, EndoC, Krt-1.19, K19, Krt1-19, cytokeratin 19, cytokeratin-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16669
HGNC: HGNC:6436
Homologene: 1713
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: alpha-E1, CD103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233651
Homologene: 2771
Slc46a2
Name: solute carrier family 46, member 2
Synonyms: 5430429N04Rik, Tscot, TSO-1C12, Ly110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 30936
Homologene: 23273
Tpo
Name: thyroid peroxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22018
Homologene: 461
Nckap5
Name: NCK-associated protein 5
Synonyms: E030049G20Rik, D130011D22Rik, LOC380609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210356
Homologene: 35542
Fmnl1
Name: formin-like 1
Synonyms: formin-related gene in leukocytes, 8030453N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Ccdc27
Name: coiled-coil domain containing 27
Synonyms: LOC381580
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381580
Homologene: 17596
4930486L24Rik
Name: RIKEN cDNA 4930486L24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 214639
VEGA: 13
Homologene: 138410
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268721
VEGA: 14
Homologene: 34313
Ceacam15
Name: carcinoembryonic antigen-related cell adhesion molecule 15
Synonyms: C430002N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101434
Homologene: 131210
Ccdc189
Name: coiled-coil domain containing 189
Synonyms: LOC233899, Gm166
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233899
Homologene: 79950
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: ether a go-go, Kv10.1, Eag1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Vill
Name: villin-like
Synonyms: Villp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22351
Homologene: 22650
Olfr385
Name: olfactory receptor 385
Synonyms: MOR135-3, GA_x6K02T2P1NL-3760313-3759375
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 259025
Homologene: 133670
Rasl10b
Name: RAS-like, family 10, member B
Synonyms: VTS58635, B230331P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276952
Homologene: 14108
Trdn
Name: triadin
Synonyms: EG432451, triadin-1, triadin 2, triadin 1, triadin 3, 2310045H21Rik, triadin-2, triadin-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76757
VEGA: 10
Homologene: 38137
Zfp707
Name: zinc finger protein 707
Synonyms: 1500031N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69020
Homologene: 18364
Mrgprb5
Name: MAS-related GPR, member B5
Synonyms: MrgB5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404239
Homologene: 115575
Qars
Name: glutaminyl-tRNA synthetase
Synonyms: 1200016L19Rik, 1110018N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 97541
HGNC: HGNC:9751
Homologene: 133975
Nars2
Name: asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244141
Homologene: 57002
Zfp3
Name: zinc finger protein 3
Synonyms: Zfp-3, Fnp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 193043
Homologene: 27406
Adgra2
Name: adhesion G protein-coupled receptor A2
Synonyms: 9530074E10Rik, 8430414O08Rik, Tem5, Gpr124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 78560
Homologene: 13112
Prl3d1
Name: prolactin family 3, subfamily d, member 1
Synonyms: PL-Ia, placental lactogen 1, Pl-1, mPL-I, Csh1, Pl1, prolactin-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18775
Homologene: 137215
Khdc1a
Name: KH domain containing 1A
Synonyms: Ndg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 368204
Homologene: 134524
Ly6g
Name: lymphocyte antigen 6 complex, locus G
Synonyms: Ly-6G, Gr-1, Gr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 546644
Homologene: 113718
Mfsd3
Name: major facilitator superfamily domain containing 3
Synonyms: 2310010G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69572
VEGA: 15
Homologene: 12318
Calml4
Name: calmodulin-like 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 75600
VEGA: 9
Homologene: 77215
Ighg
Name: Immunoglobulin heavy chain (gamma polypeptide)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 21,350,027 bp
  • G to A, chromosome 1 at 34,211,232 bp
  • A to C, chromosome 1 at 78,688,282 bp
  • T to C, chromosome 1 at 126,026,710 bp
  • A to T, chromosome 1 at 133,633,803 bp
  • G to A, chromosome 1 at 172,174,052 bp
  • A to G, chromosome 1 at 192,505,763 bp
  • T to G, chromosome 2 at 154,209,863 bp
  • T to A, chromosome 3 at 57,779,496 bp
  • T to C, chromosome 3 at 142,839,368 bp
  • A to G, chromosome 3 at 145,845,694 bp
  • T to A, chromosome 4 at 24,591,076 bp
  • G to T, chromosome 4 at 43,512,439 bp
  • A to G, chromosome 4 at 59,914,620 bp
  • T to C, chromosome 4 at 154,041,769 bp
  • T to C, chromosome 7 at 16,672,063 bp
  • A to G, chromosome 7 at 28,398,832 bp
  • A to T, chromosome 7 at 48,168,330 bp
  • A to G, chromosome 7 at 80,759,756 bp
  • G to A, chromosome 7 at 97,002,829 bp
  • TGGAGGAGGAGGAGGAGG to TGGAGGAGGAGGAGG, chromosome 7 at 100,931,037 bp
  • A to G, chromosome 7 at 105,755,571 bp
  • T to C, chromosome 7 at 127,584,981 bp
  • C to T, chromosome 7 at 132,971,333 bp
  • G to A, chromosome 7 at 138,836,727 bp
  • C to T, chromosome 8 at 27,111,088 bp
  • C to T, chromosome 9 at 7,791,106 bp
  • A to T, chromosome 9 at 62,871,266 bp
  • A to G, chromosome 9 at 108,514,008 bp
  • T to C, chromosome 9 at 119,070,820 bp
  • A to G, chromosome 9 at 119,462,506 bp
  • A to T, chromosome 10 at 33,196,132 bp
  • A to G, chromosome 10 at 85,640,596 bp
  • T to A, chromosome 11 at 70,772,636 bp
  • A to G, chromosome 11 at 73,125,362 bp
  • T to C, chromosome 11 at 73,589,543 bp
  • G to A, chromosome 11 at 83,417,839 bp
  • A to G, chromosome 11 at 100,145,425 bp
  • A to T, chromosome 11 at 103,186,709 bp
  • T to A, chromosome 12 at 30,103,110 bp
  • A to G, chromosome 12 at 53,139,520 bp
  • C to T, chromosome 12 at 113,306,821 bp
  • A to G, chromosome 12 at 116,137,330 bp
  • A to T, chromosome 13 at 27,098,710 bp
  • A to G, chromosome 13 at 60,853,506 bp
  • G to T, chromosome 14 at 20,710,748 bp
  • C to A, chromosome 14 at 70,140,109 bp
  • T to C, chromosome 15 at 75,156,766 bp
  • T to A, chromosome 15 at 75,974,616 bp
  • A to G, chromosome 15 at 76,702,689 bp
  • T to C, chromosome 15 at 98,075,853 bp
  • T to C, chromosome 16 at 33,988,803 bp
  • T to C, chromosome 16 at 43,990,722 bp
  • T to A, chromosome 17 at 34,212,369 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1389 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039451-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.