Strain Name:
C57BL/6J-MtgxR1436Btlr/Mmmh
Stock Number:
039491-MU
Citation ID:
RRID:MMRRC_039491-MU
Other Names:
R1436 (G1), C57BL/6J-MtgxR1436Btlr
Major Collection:

Gene Information

Pofut2
Name: protein O-fucosyltransferase 2
Synonyms: FUT13, 2310011G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 80294
VEGA: 10
Homologene: 12724
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20230
Homologene: 2232
Neurod4
Name: neurogenic differentiation 4
Synonyms: MATH-3, Math3, Atoh3, bHLHa4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11923
VEGA: 10
Homologene: 7234
Areg
Name: amphiregulin
Synonyms: AR, Sdgf, Mcub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11839
HGNC: HGNC:651
Homologene: 1252
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: GalNAc-T10, Galnt9, C330012K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171212
Homologene: 14924
Serpinc1
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
Synonyms: antithrombin, ATIII, At-3, At3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11905
HGNC: HGNC:775
Homologene: 20139
Itch
Name: itchy, E3 ubiquitin protein ligase
Synonyms: 6720481N21Rik, C230047C07Rik, 8030492O04Rik, AIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16396
Homologene: 88442
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: SAP155, Prp10, SF3b155, 2810001M05Rik, Targ4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 81898
Homologene: 6696
Sf3a2
Name: splicing factor 3a, subunit 2
Synonyms: SFA66, PRP11, Sap62, 66kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20222
Homologene: 133823
Zfp407
Name: zinc finger protein 407
Synonyms: LOC240469, LOC381139, 6430585N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240476
Homologene: 86402
Trip4
Name: thyroid hormone receptor interactor 4
Synonyms: ASC-1, 4930558E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56404
Homologene: 9426
Lncpint
Name: long non-protein coding RNA, Trp53 induced transcript
Synonyms: MNCb-1768, Linc-Pint, AB041803, Pint, Lincpint
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232685
Uty
Name: ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms: Hydb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22290
Gm10615
Name: predicted gene 10615
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100038739
VEGA: 9
Zbtb2
Name: zinc finger and BTB domain containing 2
Synonyms: LOC381990
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 381990
VEGA: 10
Homologene: 10837
Dbp
Name: D site albumin promoter binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13170
HGNC: HGNC:2697
Homologene: 1035
Ikbkb
Name: inhibitor of kappaB kinase beta
Synonyms: IKK-beta, IKK-2, IKK2, IKK[b], IKKbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16150
HGNC: HGNC:5960
Homologene: 7782
Stard3nl
Name: STARD3 N-terminal like
Synonyms: 0610035N01Rik, 6530409L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76205
Homologene: 11501
Ppip5k2
Name: diphosphoinositol pentakisphosphate kinase 2
Synonyms: Vip2, Hisppd1, Cfap160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227399
Homologene: 49409
Moxd1
Name: monooxygenase, DBH-like 1
Synonyms: 3230402N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 59012
Homologene: 22904
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Sec31b
Name: Sec31 homolog B (S. cerevisiae)
Synonyms: LOC240667, Sec31l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240667
Homologene: 56708
Il20ra
Name: interleukin 20 receptor, alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237313
VEGA: 10
HGNC: HGNC:6003
Homologene: 8685
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Glce
Name: glucuronyl C5-epimerase
Synonyms: heparan sulfate-glucuronic acid C5-epimerase, Hsepi, C130034A12Rik, 1110017N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 93683
Homologene: 14111
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Mi-2 alpha, Prp9-1, Prp7, 2600010P09Rik, Chd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 229003
Homologene: 14118
Ust
Name: uronyl-2-sulfotransferase
Synonyms: D930010O20Rik, UA2OST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 338362
VEGA: 10
Homologene: 4174
Nckap5
Name: NCK-associated protein 5
Synonyms: LOC380609, D130011D22Rik, E030049G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210356
Homologene: 35542
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 207792
Homologene: 19490
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224833
Homologene: 138294
Or4f7
Name: olfactory receptor family 4 subfamily F member 7
Synonyms: GA_x6K02T2N82Q-3465-3764, GA_x6K02T2Q125-72882187-72881249, MOR245-7, MOR245-7, MOR245-28_p, Olfr276, Olfr1303
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258397
Homologene: 88429
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69700
Homologene: 43567
Or4c105
Name: olfactory receptor family 4 subfamily C member 105
Synonyms: GA_x6K02T2Q125-50290367-50291296, MOR232-7, Olfr1202
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258454
Homologene: 133021
Trim46
Name: tripartite motif-containing 46
Synonyms: TRIFIC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 360213
Homologene: 11815
Mpeg1
Name: macrophage expressed gene 1
Synonyms: Mpg-1, MPS1, Perforin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17476
VEGA: 19
Homologene: 11216
Kcna5
Name: potassium voltage-gated channel, shaker-related subfamily, member 5
Synonyms: Kv1.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16493
HGNC: HGNC:6224
Homologene: 1683
Or2ad1
Name: olfactory receptor family 2 subfamily AD member 1
Synonyms: GA_x6K02T2QHY8-12104556-12105500, MOR256-15, Olfr1368
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 258527
Homologene: 105156
Ncln
Name: nicalin
Synonyms: 3100002P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103425
Homologene: 10604
Mad2l1
Name: MAD2 mitotic arrest deficient-like 1
Synonyms: MAD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56150
HGNC: HGNC:6763
Homologene: 1768
Tnk1
Name: tyrosine kinase, non-receptor, 1
Synonyms: Kos1, Tnk1b, Tnk1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83813
Homologene: 2966
Ano2
Name: anoctamin 2
Synonyms: Tmem16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243634
HGNC: HGNC:1183
Homologene: 23221
AC165412.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Lrrc39
Name: leucine rich repeat containing 39
Synonyms: 2010005E21Rik, 9430028I06Rik, Myomasp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109245
Homologene: 13668
Atg16l2
Name: autophagy related 16-like 2 (S. cerevisiae)
Synonyms: 2410118P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73683
Homologene: 18981
Pde8b
Name: phosphodiesterase 8B
Synonyms: B230331L10Rik, C030047E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218461
HGNC: HGNC:8794
Homologene: 2758
Hoxc9
Name: homeobox C9
Synonyms: Hox-3.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15427
HGNC: HGNC:5130
Homologene: 130558
Cnot6l
Name: CCR4-NOT transcription complex, subunit 6-like
Synonyms: 4932442K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231464
Homologene: 100830
Cd151
Name: CD151 antigen
Synonyms: SFA-1, PETA-3, Tspan24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12476
HGNC: HGNC:1630
Homologene: 20916
Bhmt-ps1
Name: betaine-homocysteine methyltransferase, pseudogene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 57421
Cd163
Name: CD163 antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 93671
HGNC: HGNC:1631
Homologene: 128811
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433247
Homologene: 74936
Rhot2
Name: ras homolog family member T2
Synonyms: Miro2, Arht2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 214952
Homologene: 56038
Gm5093
Name: predicted gene 5093
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328825
VEGA: 17
Ubox5
Name: U box domain containing 5
Synonyms: UIP5, 1500010O06Rik, C330018L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140629
Homologene: 8972
Syce1
Name: synaptonemal complex central element protein 1
Synonyms: 4933406J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74075
Homologene: 77044
Golim4
Name: golgi integral membrane protein 4
Synonyms: GPP130, P138, 3110027H23Rik, Golph4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73124
Homologene: 8716
Selenon
Name: selenoprotein N
Synonyms: 1110019I12Rik, Sepn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74777
Homologene: 10723
Nsun5
Name: NOL1/NOP2/Sun domain family, member 5
Synonyms: Nol1r, 9830109N13Rik, Wbscr20a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100609
Homologene: 6828
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 55,001,421 bp
  • G to A, chromosome 1 at 97,711,782 bp
  • T to C, chromosome 1 at 126,026,061 bp
  • A to G, chromosome 1 at 155,225,916 bp
  • A to G, chromosome 1 at 160,993,411 bp
  • A to T, chromosome 2 at 88,817,992 bp
  • A to G, chromosome 2 at 111,814,561 bp
  • A to C, chromosome 2 at 130,597,293 bp
  • C to A, chromosome 2 at 155,192,145 bp
  • A to T, chromosome 2 at 181,235,524 bp
  • A to T, chromosome 3 at 59,865,339 bp
  • A to G, chromosome 3 at 75,878,644 bp
  • A to G, chromosome 3 at 89,243,661 bp
  • A to T, chromosome 3 at 116,579,644 bp
  • A to G, chromosome 4 at 26,369,591 bp
  • T to A, chromosome 4 at 134,540,686 bp
  • G to T, chromosome 5 at 91,139,805 bp
  • T to A, chromosome 5 at 96,134,112 bp
  • T to C, chromosome 5 at 124,762,221 bp
  • T to C, chromosome 5 at 135,370,213 bp
  • G to A, chromosome 6 at 31,181,039 bp
  • T to A, chromosome 6 at 66,539,813 bp
  • T to C, chromosome 6 at 121,644,213 bp
  • T to C, chromosome 6 at 124,327,931 bp
  • T to C, chromosome 6 at 125,867,171 bp
  • T to A, chromosome 6 at 126,534,761 bp
  • T to C, chromosome 7 at 45,708,455 bp
  • A to G, chromosome 7 at 101,291,550 bp
  • C to T, chromosome 7 at 140,777,680 bp
  • A to T, chromosome 7 at 141,469,284 bp
  • T to A, chromosome 8 at 22,673,403 bp
  • C to T, chromosome 9 at 62,070,010 bp
  • A to T, chromosome 9 at 65,880,951 bp
  • T to A, chromosome 9 at 110,118,640 bp
  • T to C, chromosome 10 at 4,368,697 bp
  • G to A, chromosome 10 at 8,307,438 bp
  • T to A, chromosome 10 at 19,749,252 bp
  • C to T, chromosome 10 at 24,244,358 bp
  • C to T, chromosome 10 at 77,268,564 bp
  • G to A, chromosome 10 at 80,804,206 bp
  • C to T, chromosome 10 at 81,489,893 bp
  • T to C, chromosome 10 at 130,270,671 bp
  • T to C, chromosome 11 at 9,292,646 bp
  • T to C, chromosome 11 at 57,771,469 bp
  • A to T, chromosome 11 at 69,357,574 bp
  • G to T, chromosome 11 at 69,852,293 bp
  • C to T, chromosome 13 at 19,372,649 bp
  • G to T, chromosome 13 at 21,142,992 bp
  • T to C, chromosome 13 at 95,026,170 bp
  • A to G, chromosome 15 at 71,922,957 bp
  • T to C, chromosome 15 at 102,981,872 bp
  • A to C, chromosome 17 at 25,841,400 bp
  • C to G, chromosome 17 at 46,439,754 bp
  • C to T, chromosome 17 at 47,466,702 bp
  • T to G, chromosome 17 at 51,804,363 bp
  • C to A, chromosome 17 at 74,652,705 bp
  • A to G, chromosome 18 at 84,343,071 bp
  • C to T, chromosome 19 at 12,462,459 bp
  • A to G, chromosome 19 at 39,741,040 bp
  • T to C, chromosome 19 at 44,536,195 bp
  • A to G, chromosome Y at 1,197,202 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1436 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039491-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.