Strain Name:
C57BL/6J-MtgxR1438Btlr/Mmmh
Stock Number:
039493-MU
Citation ID:
RRID:MMRRC_039493-MU
Other Names:
R1438 (G1), C57BL/6J-MtgxR1438Btlr
Major Collection:

Gene Information

Wnt3
Name: wingless-type MMTV integration site family, member 3
Synonyms: Wnt-3, Int-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22415
Homologene: 22527
Dnajc3
Name: DnaJ heat shock protein family (Hsp40) member C3
Synonyms: Prkri, Dnajc3a, Dnajc3, Dnajc3b, mp58, p58IPK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100037258
VEGA: 14
HGNC: HGNC:9439
Homologene: 2486
Kcnc1
Name: potassium voltage gated channel, Shaw-related subfamily, member 1
Synonyms: NGK2, Shaw, C230009H10Rik, Kcr2-1, Kv3.1, KV4, KShIIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16502
HGNC: HGNC:6233
Homologene: 68134
Rorb
Name: RAR-related orphan receptor beta
Synonyms: Nr1f2, RZR-beta, Rorbeta, hstp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225998
Homologene: 38250
Prtg
Name: protogenin
Synonyms: A230098A12Rik, Igdcc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235472
Homologene: 54453
Sec23a
Name: SEC23 homolog A, COPII coat complex component
Synonyms: Sec23r, Msec23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20334
Homologene: 4642
Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: Adprt1, parp-1, sPARP-1, PARP, 5830444G22Rik, Adprp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11545
HGNC: HGNC:270
Homologene: 1222
Cct2
Name: chaperonin containing Tcp1, subunit 2 (beta)
Synonyms: Cctb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12461
VEGA: 10
HGNC: HGNC:1615
Homologene: 4696
Septin11
Name: septin 11
Synonyms: Sept11, D5Ertd606e, 6230410I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52398
Homologene: 56800
Ptpn1
Name: protein tyrosine phosphatase, non-receptor type 1
Synonyms: PTP1B, PTP-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19246
HGNC: HGNC:9642
Homologene: 2119
Akap1
Name: A kinase (PRKA) anchor protein 1
Synonyms: AKAP121, DAKAP1, S-AKAP84, AKAP84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11640
HGNC: HGNC:367
Homologene: 31165
Emsy
Name: EMSY, BRCA2-interacting transcriptional repressor
Synonyms: 2210018M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233545
Homologene: 32465
Afdn
Name: afadin, adherens junction formation factor
Synonyms: Mllt4, 5033403D15Rik, Afadin, I-afadin, S-afadin, AF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: Snrp116, 116kDa, U5-116kD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20624
Homologene: 3133
Chchd3
Name: coiled-coil-helix-coiled-coil-helix domain containing 3
Synonyms: 0610041L09Rik, Micos19, 1700039J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66075
Homologene: 9851
Dek
Name: DEK oncogene (DNA binding)
Synonyms: D13H6S231E, 1810019E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110052
HGNC: HGNC:2768
Homologene: 2593
Nkapd1
Name: NKAP domain containing 1
Synonyms: LOC270156, AU019823
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270156
Homologene: 41233
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: C130099L13Rik, 8430405D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 195018
Homologene: 9027
Uvssa
Name: UV stimulated scaffold protein A
Synonyms: D330017J19Rik, 4933407H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71101
Homologene: 13807
Rtn1
Name: reticulon 1
Synonyms: Rtn1-b, Rtn1-a, 4930441F12Rik, 0710005K15Rik, Rtn1-c, Nsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104001
Homologene: 49654
Scube1
Name: signal peptide, CUB domain, EGF-like 1
Synonyms: A630023E24Rik, 7330410C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 64706
Homologene: 11224
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: cat eye syndrome chromosome region, candidate 2, 2610101O16Rik, 2810409N01Rik, Gtl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Dhx32
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 32
Synonyms: Ddx32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101437
Homologene: 56798
Rreb1
Name: ras responsive element binding protein 1
Synonyms: B930013M22Rik, 1110037N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68750
Homologene: 2218
Boc
Name: biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 117606
Homologene: 32819
Elp6
Name: elongator acetyltransferase complex subunit 6
Synonyms: 2610001P13Rik, Tmem103, 2610002I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72341
Homologene: 9794
Rbm19
Name: RNA binding motif protein 19
Synonyms: 1200009A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74111
Homologene: 7158
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98432
Homologene: 11015
Rai1
Name: retinoic acid induced 1
Synonyms: Gt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19377
HGNC: HGNC:9834
Homologene: 7508
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, Fath2, LOC245827, mKIAA0811
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 53867
Homologene: 9253
Prdm1
Name: PR domain containing 1, with ZNF domain
Synonyms: PRDI-BF1, Blimp1, b2b1765Clo, Blimp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12142
HGNC: HGNC:9346
Homologene: 925
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Exoc3
Name: exocyst complex component 3
Synonyms: Sec6l1, E430013E20Rik, 2810050O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 211446
VEGA: 13
Homologene: 38296
Ifit1bl2
Name: interferon induced protein with tetratricopeptide repeats 1B like 2
Synonyms: 2010002M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 112419
Homologene: 78213
Mmp3
Name: matrix metallopeptidase 3
Synonyms: SLN-1, stromelysin-1, STR-1, progelatinase, stromelysin 1, Stmy1, SLN1, Str1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17392
VEGA: 9
HGNC: HGNC:7173
Homologene: 20545
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320484
Homologene: 18901
Hivep1
Name: human immunodeficiency virus type I enhancer binding protein 1
Synonyms: alphaA-CRYBP1, Cryabp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110521
VEGA: 13
HGNC: HGNC:4920
Homologene: 1596
Aox3
Name: aldehyde oxidase 3
Synonyms: 1200011D03Rik, AOH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71724
Homologene: 90899
Nrxn3
Name: neurexin III
Synonyms: 9330112C09Rik, D12Bwg0831e, neurexin III alpha, neurexin III beta, neurexin III beta, neurexin III alpha, 4933401A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Gpr39
Name: G protein-coupled receptor 39
Synonyms: 4933415E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71111
HGNC: HGNC:4496
Homologene: 20380
Kctd21
Name: potassium channel tetramerisation domain containing 21
Synonyms: EG622320
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 622320
Homologene: 54754
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Actl6b
Name: actin-like 6B
Synonyms: Baf53b, ArpNa, Actl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83766
HGNC: HGNC:160
Homologene: 81844
Fsd2
Name: fibronectin type III and SPRY domain containing 2
Synonyms: 9830160G03Rik, Spryd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244091
Homologene: 18252
Lbp
Name: lipopolysaccharide binding protein
Synonyms: Bpifd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16803
HGNC: HGNC:6517
Homologene: 3055
Pcdhb19
Name: protocadherin beta 19
Synonyms: PcdhbS, Pcdhb11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93890
HGNC: HGNC:8683
Homologene: 128411
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330222
Homologene: 27395
Gucy1b2
Name: guanylate cyclase 1, soluble, beta 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239134
HGNC: HGNC:4686
Homologene: 136630
Adam24
Name: a disintegrin and metallopeptidase domain 24 (testase 1)
Synonyms: Dtgn5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13526
HGNC: HGNC:203
Homologene: 137232
Mief2
Name: mitochondrial elongation factor 2
Synonyms: LOC237781, Smcr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237781
Homologene: 27354
Olfr1126
Name: olfactory receptor 1126
Synonyms: GA_x6K02T2Q125-48959068-48960012, MOR264-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258834
Homologene: 133659
Tas2r118
Name: taste receptor, type 2, member 118
Synonyms: mGR18, Tas2r18, T2R18, mt2r40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387347
Homologene: 9660
Adgrg6
Name: adhesion G protein-coupled receptor G6
Synonyms: LOC215798, DREG, Gpr126, 1190004A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215798
Homologene: 10724
Ptprr
Name: protein tyrosine phosphatase, receptor type, R
Synonyms: RPTPRR, PTPBR7, PTP-SL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19279
HGNC: HGNC:9680
Homologene: 2135
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 215384
Homologene: 68369
Sgf29
Name: SAGA complex associated factor 29
Synonyms: 1700023O11Rik, Ccdc101
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75565
Homologene: 12607
Ckmt2
Name: creatine kinase, mitochondrial 2
Synonyms: ScCKmit, 2300008A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76722
HGNC: HGNC:1996
Homologene: 68206
Ripply2
Name: ripply transcriptional repressor 2
Synonyms: LOC382089, C030002E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382089
Homologene: 19960
Vmn2r81
Name: vomeronasal 2, receptor 81
Synonyms: EC1-VR2, pheromone recepter, V2rf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216144
Homologene: 83483
Thoc5
Name: THO complex 5
Synonyms: Fmip, 1700060C24Rik, A430085L24Rik, PK1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107829
Homologene: 37836
Cd84
Name: CD84 antigen
Synonyms: CDw84, SLAMF5, A130013D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Vmn2r50
Name: vomeronasal 2, receptor 50
Synonyms: EG434117
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434117
Homologene: 113703
Smo
Name: smoothened, frizzled class receptor
Synonyms: E130215L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319757
Homologene: 4115
Zswim9
Name: zinc finger SWIM-type containing 9
Synonyms: 6330408A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 321008
Homologene: 52386
Cchcr1
Name: coiled-coil alpha-helical rod protein 1
Synonyms: Hcr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240084
Homologene: 10396
Tmem33
Name: transmembrane protein 33
Synonyms: 1110006G02Rik, 1600019D15Rik, 2700052H22Rik, 5430406L04Rik, 2410089A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67878
Homologene: 10018
Top1mt
Name: DNA topoisomerase 1, mitochondrial
Synonyms: 2900052H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72960
Homologene: 43082
Fosl2
Name: fos-like antigen 2
Synonyms: Fra-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14284
HGNC: HGNC:3798
Homologene: 3845
Golim4
Name: golgi integral membrane protein 4
Synonyms: 3110027H23Rik, Golph4, GPP130, P138
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73124
Homologene: 8716
Olfr57
Name: olfactory receptor 57
Synonyms: IF12, GA_x6K02T2QGN0-2777431-2776472, MOR139-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18357
HGNC: HGNC:8368
Homologene: 133620
Rhbdd3
Name: rhomboid domain containing 3
Synonyms: 5730411O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 279766
HGNC: HGNC:1308
Homologene: 8175
Rnf183
Name: ring finger protein 183
Synonyms: 5830442J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76072
Homologene: 44917
Tada2a
Name: transcriptional adaptor 2A
Synonyms: D030022J10Rik, Tada2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217031
Homologene: 38834
Rpl7a-ps5
Name: ribosomal protein L7A, pseudogene 5
Synonyms: Gm16375
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 674419
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 58,153,178 bp
  • A to G, chromosome 1 at 106,173,412 bp
  • T to C, chromosome 1 at 125,872,356 bp
  • A to T, chromosome 1 at 171,852,118 bp
  • A to G, chromosome 1 at 180,591,242 bp
  • A to G, chromosome 2 at 87,457,992 bp
  • T to C, chromosome 2 at 112,757,701 bp
  • T to A, chromosome 2 at 158,314,137 bp
  • T to C, chromosome 2 at 167,976,609 bp
  • T to A, chromosome 2 at 180,182,800 bp
  • A to C, chromosome 3 at 75,956,133 bp
  • A to G, chromosome 4 at 62,428,523 bp
  • A to G, chromosome 4 at 113,556,111 bp
  • T to A, chromosome 5 at 32,146,985 bp
  • T to A, chromosome 5 at 33,413,884 bp
  • T to A, chromosome 5 at 67,267,291 bp
  • T to C, chromosome 5 at 93,148,428 bp
  • A to G, chromosome 5 at 120,122,896 bp
  • A to G, chromosome 5 at 124,798,945 bp
  • A to T, chromosome 5 at 137,554,609 bp
  • A to T, chromosome 5 at 142,038,323 bp
  • T to A, chromosome 6 at 23,969,423 bp
  • G to A, chromosome 6 at 29,755,483 bp
  • C to A, chromosome 6 at 33,008,568 bp
  • T to A, chromosome 6 at 120,761,472 bp
  • A to T, chromosome 7 at 10,050,135 bp
  • A to G, chromosome 7 at 13,277,218 bp
  • T to A, chromosome 7 at 28,103,733 bp
  • A to T, chromosome 7 at 46,428,267 bp
  • T to C, chromosome 7 at 81,548,873 bp
  • T to A, chromosome 7 at 97,347,497 bp
  • C to T, chromosome 7 at 98,621,406 bp
  • G to A, chromosome 7 at 126,671,891 bp
  • T to C, chromosome 7 at 133,737,340 bp
  • A to T, chromosome 8 at 40,681,392 bp
  • T to C, chromosome 9 at 7,453,705 bp
  • T to C, chromosome 9 at 20,779,957 bp
  • C to A, chromosome 9 at 50,607,672 bp
  • C to T, chromosome 9 at 72,910,750 bp
  • T to C, chromosome 9 at 87,019,660 bp
  • T to C, chromosome 9 at 110,314,055 bp
  • T to C, chromosome 10 at 14,468,841 bp
  • T to C, chromosome 10 at 44,442,128 bp
  • T to A, chromosome 10 at 79,035,288 bp
  • A to G, chromosome 10 at 79,293,857 bp
  • T to C, chromosome 10 at 116,256,204 bp
  • A to T, chromosome 10 at 117,054,992 bp
  • A to T, chromosome 11 at 4,911,427 bp
  • T to A, chromosome 11 at 5,103,332 bp
  • A to T, chromosome 11 at 55,287,811 bp
  • T to G, chromosome 11 at 60,185,395 bp
  • G to T, chromosome 11 at 60,730,314 bp
  • T to C, chromosome 11 at 72,912,945 bp
  • G to A, chromosome 11 at 84,110,011 bp
  • C to A, chromosome 11 at 88,844,751 bp
  • G to T, chromosome 11 at 102,860,042 bp
  • A to T, chromosome 11 at 103,808,251 bp
  • A to T, chromosome 12 at 59,002,010 bp
  • A to T, chromosome 12 at 72,304,413 bp
  • C to T, chromosome 12 at 90,332,135 bp
  • A to G, chromosome 13 at 37,930,605 bp
  • A to G, chromosome 13 at 42,158,120 bp
  • A to T, chromosome 13 at 47,088,171 bp
  • A to T, chromosome 13 at 74,190,179 bp
  • A to T, chromosome 13 at 74,224,868 bp
  • A to T, chromosome 13 at 91,859,852 bp
  • T to A, chromosome 14 at 24,154,605 bp
  • T to C, chromosome 14 at 62,414,321 bp
  • A to G, chromosome 14 at 118,968,106 bp
  • A to G, chromosome 15 at 75,674,398 bp
  • A to G, chromosome 15 at 83,615,026 bp
  • A to T, chromosome 16 at 44,488,746 bp
  • T to A, chromosome 17 at 13,855,390 bp
  • T to A, chromosome 17 at 32,393,535 bp
  • T to C, chromosome 17 at 35,530,560 bp
  • C to T, chromosome 17 at 57,839,140 bp
  • A to G, chromosome 18 at 37,497,962 bp
  • A to G, chromosome 19 at 18,955,053 bp
  • T to A, chromosome 19 at 34,619,169 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1438 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039493-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.