Strain Name:
C57BL/6J-MtgxR1486Btlr/Mmmh
Stock Number:
039539-MU
Citation ID:
RRID:MMRRC_039539-MU
Other Names:
R1486 (G1), C57BL/6J-MtgxR1486Btlr
Major Collection:

Strain Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Card11
Name: caspase recruitment domain family, member 11
Synonyms: CARMA1, BIMP3, 2410011D02Rik, 0610008L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 108723
Homologene: 13024
Nrg1
Name: neuregulin 1
Synonyms: HGL, HRG, Hgl, SMDF, GGF, ARIA, heregulin, D230005F13Rik, HRGalpha, 6030402G23Rik, GGFII, NDF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Mta1
Name: metastasis associated 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 116870
HGNC: HGNC:7410
Homologene: 3442
Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
Synonyms: RAB5 effector protein, neurocrescin, rabaptin-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 54189
Homologene: 3451
Atf6
Name: activating transcription factor 6
Synonyms: ESTM49, 9130025P16Rik, Atf6alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226641
HGNC: HGNC:791
Homologene: 32015
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: TPRD, D16Ium21, 2610202A04Rik, D16Ium21e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22129
Homologene: 2487
Sin3b
Name: transcriptional regulator, SIN3B (yeast)
Synonyms: 2810430C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20467
Homologene: 81810
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CS group B correcting gene, CSB, C130058G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, D630048A14Rik, Ki67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Eif3c
Name: eukaryotic translation initiation factor 3, subunit C
Synonyms: NIPIL(A3), 110kDa, 3230401O13Rik, Eif3s8, Xsl, Xs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56347
Homologene: 2781
Chek2
Name: checkpoint kinase 2
Synonyms: CHK2, Rad53
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50883
Homologene: 38289
Nup37
Name: nucleoporin 37
Synonyms: 2410003L22Rik, 2810039M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69736
VEGA: 10
Homologene: 11441
Iws1
Name: IWS1, SUPT6 interacting protein
Synonyms: 1700069O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 73473
Homologene: 134421
Grm4
Name: glutamate receptor, metabotropic 4
Synonyms: mGluR4, Gprc1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268934
HGNC: HGNC:4596
Homologene: 20230
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: 5830462I21Rik, JHDM2B, Jmjd1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Rasal1
Name: RAS protein activator like 1 (GAP1 like)
Synonyms: MRASAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19415
HGNC: HGNC:9873
Homologene: 3423
Mphosph8
Name: M-phase phosphoprotein 8
Synonyms: 1500035L22Rik, 4930548G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75339
Homologene: 11380
Zfp451
Name: zinc finger protein 451
Synonyms: Kiaa0576-hp, 4933435G09Rik, 4930515K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98403
Homologene: 9188
Il22
Name: interleukin 22
Synonyms: IL-TIF, IL-22, Iltif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50929
Homologene: 9669
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100604
Homologene: 12997
Gipc1
Name: GIPC PDZ domain containing family, member 1
Synonyms: synectin, TIP-2, Semcap1, neurophilin1-IP, Glut1CIP, TaxIP2, Rgs19ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67903
HGNC: HGNC:1226
Homologene: 21167
Bhlhe40
Name: basic helix-loop-helix family, member e40
Synonyms: eip1 (E47 interaction protein 1), Stra13, CR8, cytokine response gene 8, Clast5, C130042M06Rik, Stra14, DEC1, Sharp2, Bhlhb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20893
HGNC: HGNC:1046
Homologene: 2722
Hps3
Name: HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Synonyms: Hermansky-Pudlak syndrome 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12807
Homologene: 13019
Spats2l
Name: spermatogenesis associated, serine-rich 2-like
Synonyms: A230104H11Rik, 2810022L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67198
Homologene: 56711
Itga9
Name: integrin alpha 9
Synonyms: 2610002H11Rik, D9Ertd428e, 6720458D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 104099
HGNC: HGNC:6145
Homologene: 1664
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Ncdn
Name: neurochondrin
Synonyms: neurochondrin-2, neurochondrin-1, norbin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26562
Homologene: 8064
Irak3
Name: interleukin-1 receptor-associated kinase 3
Synonyms: IRAK-M, 4833428C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73914
Homologene: 36215
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228602
Homologene: 12623
Pcyox1l
Name: prenylcysteine oxidase 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240334
Homologene: 23429
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Tmc5
Name: transmembrane channel-like gene family 5
Synonyms: 4932443L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74424
Homologene: 11713
Acrbp
Name: proacrosin binding protein
Synonyms: sp32, OY-TES-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54137
Homologene: 9641
Sobp
Name: sine oculis binding protein
Synonyms: 2900009C16Rik, 5330439J01Rik, Jxc1, jc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109205
Homologene: 41216
Adamtsl4
Name: ADAMTS-like 4
Synonyms: Tsrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229595
Homologene: 23141
A730018C14Rik
Name: RIKEN cDNA A730018C14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 100504733
VEGA: 12
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237711
Homologene: 104282
Sqor
Name: sulfide quinone oxidoreductase
Synonyms: flavo-binding protein, 4930557M22Rik, 0610039J17Rik, Sqrdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 59010
Homologene: 10921
Or52s19
Name: olfactory receptor family 52 subfamily S member 19
Synonyms: GA_x6K02T2PBJ9-6068534-6067590, MOR24-3, Olfr601
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258311
Homologene: 64851
Or8j3c
Name: olfactory receptor family 8 subfamily J member 3C
Synonyms: GA_x6K02T2Q125-47892992-47892045, MOR185-1, Olfr1062
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259082
Homologene: 83135
Irx6
Name: Iroquois homeobox 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64379
Homologene: 41481
Catsperg1
Name: cation channel sperm associated auxiliary subunit gamma 1
Synonyms: A230107C01Rik, Catsperg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320225
Homologene: 10915
Apba2
Name: amyloid beta (A4) precursor protein-binding, family A, member 2
Synonyms: X11-like, X11L, Mint 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11784
HGNC: HGNC:579
Homologene: 4021
Skint11
Name: selection and upkeep of intraepithelial T cells 11
Synonyms: A630098G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230623
Homologene: 136292
Pcgf1
Name: polycomb group ring finger 1
Synonyms: 2010002K04Rik, Nspc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69837
Homologene: 13090
Kti12
Name: KTI12 homolog, chromatin associated
Synonyms: 1110001A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100087
Homologene: 6347
Nt5el
Name: 5' nucleotidase, ecto-like
Synonyms: 4933425L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66763
Homologene: 12028
Potefam1
Name: POTE ankyrin domain family member 1
Synonyms: Pote1, 4930430A15Rik, A26c3, Potea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67575
Homologene: 69410
Or51f1e
Name: olfactory receptor family 51 subfamily F member 1E
Synonyms: GA_x6K02T2PBJ9-5809085-5810035, MOR14-4, Olfr585
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259091
Homologene: 133721
Stox1
Name: storkhead box 1
Synonyms: 4732470K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216021
Homologene: 17649
Rep15
Name: RAB15 effector protein
Synonyms: 2210417D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66532
Homologene: 11985
Prxl2b
Name: peroxiredoxin like 2B
Synonyms: PM/PGFS, 2810405K02Rik, Fam213b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66469
Homologene: 11976
Or1ad1
Name: olfactory receptor family 1 subfamily AD member 1
Synonyms: GA_x6K02T2QP88-4453480-4452557, MOR129-1, Olfr1377
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258913
Homologene: 64929
Cep20
Name: centrosomal protein 20
Synonyms: 0610037P05Rik, Fopnl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66086
Homologene: 11919
Tor4a
Name: torsin family 4, member A
Synonyms: A830007P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227612
Homologene: 17140
Rbm12b2
Name: RNA binding motif protein 12 B2
Synonyms: C430048L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77604
Homologene: 28658
Gm1070
Name: predicted gene 1070
Synonyms: LOC381785
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381785
Prps1l3
Name: phosphoribosyl pyrophosphate synthetase 1-like 3
Synonyms: Gm5081
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328099
HGNC: HGNC:9462
Homologene: 68565
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 33,777,727 bp
  • T to C, chromosome 1 at 57,900,811 bp
  • A to G, chromosome 1 at 170,794,691 bp
  • A to T, chromosome 2 at 25,194,679 bp
  • T to A, chromosome 2 at 86,423,481 bp
  • T to G, chromosome 2 at 111,200,358 bp
  • G to A, chromosome 2 at 122,807,645 bp
  • A to G, chromosome 2 at 130,737,418 bp
  • A to T, chromosome 3 at 20,019,972 bp
  • T to C, chromosome 3 at 95,681,856 bp
  • A to G, chromosome 4 at 12,094,841 bp
  • A to G, chromosome 4 at 108,847,946 bp
  • G to A, chromosome 4 at 114,194,818 bp
  • A to T, chromosome 4 at 126,748,598 bp
  • A to T, chromosome 4 at 154,898,685 bp
  • T to A, chromosome 5 at 105,607,529 bp
  • T to G, chromosome 5 at 110,841,227 bp
  • T to C, chromosome 5 at 120,654,852 bp
  • T to C, chromosome 5 at 140,876,519 bp
  • A to G, chromosome 6 at 71,300,350 bp
  • T to G, chromosome 6 at 83,079,126 bp
  • T to C, chromosome 6 at 108,664,929 bp
  • T to A, chromosome 6 at 125,050,622 bp
  • T to A, chromosome 6 at 147,033,079 bp
  • C to A, chromosome 7 at 29,185,495 bp
  • T to C, chromosome 7 at 64,736,948 bp
  • A to T, chromosome 7 at 103,098,430 bp
  • T to A, chromosome 7 at 103,358,994 bp
  • C to T, chromosome 7 at 118,673,432 bp
  • C to T, chromosome 7 at 126,564,721 bp
  • G to A, chromosome 7 at 135,699,720 bp
  • T to C, chromosome 8 at 31,818,344 bp
  • A to G, chromosome 8 at 72,750,513 bp
  • C to T, chromosome 8 at 83,661,179 bp
  • T to A, chromosome 8 at 92,677,200 bp
  • C to A, chromosome 9 at 67,311,839 bp
  • T to G, chromosome 9 at 118,626,450 bp
  • T to G, chromosome 10 at 43,022,522 bp
  • T to C, chromosome 10 at 52,172,858 bp
  • T to C, chromosome 10 at 62,664,636 bp
  • T to C, chromosome 10 at 88,148,254 bp
  • T to C, chromosome 10 at 118,205,644 bp
  • T to C, chromosome 10 at 120,143,061 bp
  • A to C, chromosome 11 at 29,805,114 bp
  • G to A, chromosome 11 at 50,984,781 bp
  • A to T, chromosome 11 at 65,834,272 bp
  • A to G, chromosome 11 at 70,919,285 bp
  • T to A, chromosome 11 at 72,754,323 bp
  • C to T, chromosome 12 at 57,238,787 bp
  • T to C, chromosome 12 at 112,415,695 bp
  • T to C, chromosome 12 at 113,135,793 bp
  • T to C, chromosome 13 at 105,109,783 bp
  • C to T, chromosome 14 at 32,552,720 bp
  • C to T, chromosome 14 at 56,689,039 bp
  • A to G, chromosome 16 at 14,300,140 bp
  • G to A, chromosome 16 at 94,448,129 bp
  • A to G, chromosome 17 at 27,434,717 bp
  • G to T, chromosome 17 at 74,639,820 bp
  • T to C, chromosome 18 at 32,097,256 bp
  • T to A, chromosome 18 at 34,834,304 bp
  • C to T, chromosome 18 at 61,699,515 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1486 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039539-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.