Strain Name:
C57BL/6J-MtgxR1497Btlr/Mmmh
Stock Number:
039548-MU
Citation ID:
RRID:MMRRC_039548-MU
Other Names:
R1497 (G1), C57BL/6J-MtgxR1497Btlr
Major Collection:

Strain Information

Hyal1
Name: hyaluronoglucosaminidase 1
Synonyms: Hyal-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15586
HGNC: HGNC:5320
Homologene: 5277
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: Mll3, HALR, E330008K23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231051
Homologene: 46480
Mbd5
Name: methyl-CpG binding domain protein 5
Synonyms: 9430004D19Rik, OTTMUSG00000012483, C030040A15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 109241
Homologene: 81861
Shc1
Name: src homology 2 domain-containing transforming protein C1
Synonyms: p66shc, ShcA, p66
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20416
Homologene: 7934
Magi1
Name: membrane associated guanylate kinase, WW and PDZ domain containing 1
Synonyms: Baiap1, Gukmi1, WWP3, BAP1, AIP3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14924
HGNC: HGNC:946
Homologene: 31257
Clasp1
Name: CLIP associating protein 1
Synonyms: mCLASP1, 1700030C23Rik, 5730583A19Rik, CLASP1alpha, CLASP1, B130045P17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76707
Homologene: 41024
Sik3
Name: SIK family kinase 3
Synonyms: 5730525O22Rik, 9030204A07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Kif13b
Name: kinesin family member 13B
Synonyms: C130021D12Rik, N-3 kinesin, GAKIN, 5330429L19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Ctc1
Name: CTS telomere maintenance complex component 1
Synonyms: 1500010J02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68964
Homologene: 11830
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382038
Homologene: 8859
Ezr
Name: ezrin
Synonyms: cytovillin, p81, Vil2, ezrin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22350
Homologene: 55740
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 84505
Homologene: 32157
Bcas3
Name: BCAS3 microtubule associated cell migration factor
Synonyms: breast carcinoma amplified sequence 3, K20D4, 2610028P08Rik, 1500019F07Rik, rudhira, Phaf2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192197
Homologene: 9778
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 3526402J09Rik, 5730590C14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77097
Homologene: 64680
Fam193b
Name: family with sequence similarity 193, member B
Synonyms: IRIZIO
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 212483
VEGA: 13
Homologene: 130095
Clec16a
Name: C-type lectin domain family 16, member A
Synonyms: 4932416N17Rik, curt
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74374
Homologene: 71019
Gabpb1
Name: GA repeat binding protein, beta 1
Synonyms: NRF2B1, E4TF1, GABPB1-1, GABPB1-2, BABPB2, E4TF1-53, NRF2B2, E4Tf1B, E4TF1-47
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14391
HGNC: HGNC:4074
Homologene: 7723
Gtf3c3
Name: general transcription factor IIIC, polypeptide 3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98488
HGNC: HGNC:4666
Homologene: 40805
Ipo13
Name: importin 13
Synonyms: Imp13, Kap13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230673
Homologene: 40968
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Trim66
Name: tripartite motif-containing 66
Synonyms: Tif1d, D7H11orf29
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330627
Homologene: 28044
Dhx8
Name: DEAH-box helicase 8
Synonyms: Ddx8, mDEAH6, RNA helicase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217207
HGNC: HGNC:2749
Homologene: 3628
Anapc7
Name: anaphase promoting complex subunit 7
Synonyms: prediabetic NOD sera-reactive autoantigen, APC7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56317
Homologene: 10512
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: BC016423, Fam208b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Epm2aip1
Name: EPM2A interacting protein 1
Synonyms: EPM2A (laforin) interacting protein 1, A930003G21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77781
Homologene: 8875
Fcrl1
Name: Fc receptor-like 1
Synonyms: A230020G22Rik, mBXMH1, moFcRH1L, moFcRH1S, mIFGP1, IFGP1, Fcrh1, moFcRH1, BXMAS1-like
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229499
Homologene: 50472
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Plc, per, Pcn, perlecan
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Nipsnap2
Name: nipsnap homolog 2
Synonyms: Nipsnap2, Gbas
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14467
HGNC: HGNC:4179
Homologene: 1137
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, FLASH
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26885
HGNC: HGNC:1510
Homologene: 8066
Maml1
Name: mastermind like transcriptional coactivator 1
Synonyms: D930008C07Rik, Mam-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103806
Homologene: 8845
Tbc1d19
Name: TBC1 domain family, member 19
Synonyms: 2810453K03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67249
Homologene: 10130
Dhtkd1
Name: dehydrogenase E1 and transketolase domain containing 1
Synonyms: C330018I04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 209692
Homologene: 10278
Pnkd
Name: paroxysmal nonkinesiogenic dyskinesia
Synonyms: 2810403H05Rik, Brp17, 2210013N15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56695
HGNC: HGNC:9153
Homologene: 75045
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Vmn1r206
Name: vomeronasal 1 receptor 206
Synonyms: V1rh7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171250
Homologene: 110880
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20265
Homologene: 21375
Mcu
Name: mitochondrial calcium uniporter
Synonyms: D130073L02Rik, Ccdc109a, 2010012O16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215999
Homologene: 9916
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Acc2, Accb
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, Dnahc17, Dnahcl1, 2810003K23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Pcnx4
Name: pecanex homolog 4
Synonyms: Pcnxl4, 1810048J11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67708
VEGA: 12
Homologene: 23366
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237979
Homologene: 10406
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244484
Homologene: 12460
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: 4832426G23Rik, Myhs-p, MyHC-pn, Myhsp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Zfp804b
Name: zinc finger protein 804B
Synonyms: LOC207618
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207618
Homologene: 52304
Cyp2d41-ps
Name: cytochrome P450, family 2, subfamily d, member 41, pseudogene
Synonyms: Gm5062
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271300
Tdrd5
Name: tudor domain containing 5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214575
Homologene: 18312
Abca8b
Name: ATP-binding cassette, sub-family A member 8b
Synonyms: Abca8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Caskin1
Name: CASK interacting protein 1
Synonyms: 3300002N10Rik, C630036E02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268932
VEGA: 17
Homologene: 25873
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225898
VEGA: 19
Homologene: 27044
Mndal
Name: myeloid nuclear differentiation antigen like
Synonyms: Ifi212
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100040462
HGNC: HGNC:5395
Homologene: 115929
Tmed6
Name: transmembrane p24 trafficking protein 6
Synonyms: 1810018I24Rik, 1810015P03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66269
Homologene: 11938
Flg2
Name: filaggrin family member 2
Synonyms: EG229574
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229574
Homologene: 134146
Tex22
Name: testis expressed gene 22
Synonyms: Tep22, 1700028O09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75671
Homologene: 84861
Afap1l2
Name: actin filament associated protein 1-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226250
Homologene: 13057
Cyp2j6
Name: cytochrome P450, family 2, subfamily j, polypeptide 6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13110
HGNC: HGNC:2634
Homologene: 68091
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Adgrc3, Fmi1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Ppp4r4
Name: protein phosphatase 4, regulatory subunit 4
Synonyms: 8430415E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74521
Homologene: 12571
Mpeg1
Name: macrophage expressed gene 1
Synonyms: Mpg-1, Perforin-2, MPS1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17476
VEGA: 19
Homologene: 11216
Vmn2r92
Name: vomeronasal 2, receptor 92
Synonyms: EG627111
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627111
Homologene: 115024
Tex14
Name: testis expressed gene 14 intercellular bridge forming factor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 83560
Homologene: 12838
Mettl21c
Name: methyltransferase 21C, AARS1 lysine
Synonyms: A530098C11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 433294
Homologene: 45916
Spata7
Name: spermatogenesis associated 7
Synonyms: HSD3, B230306G18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104871
Homologene: 10189
Vmn1r185
Name: vomeronasal 1 receptor 185
Synonyms: V1re12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171265
Homologene: 74353
Or4a66
Name: olfactory receptor family 4 subfamily A member 66
Synonyms: Olfr1196, GA_x6K02T2Q125-50181139-50180195, MOR225-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258456
Homologene: 123770
Usb1
Name: U6 snRNA biogenesis 1
Synonyms: AA960436
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 101985
Homologene: 11611
Fam217a
Name: family with sequence similarity 217, member A
Synonyms: 1700026J04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71864
VEGA: 13
Homologene: 82344
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR-3, Flt-4, VEGFR3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Nlrp4e
Name: NLR family, pyrin domain containing 4E
Synonyms: 4930406H16Rik, Nalp4e, Nalp-epsilon
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446099
Homologene: 75315
Ccdc68
Name: coiled-coil domain containing 68
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 381175
Homologene: 11880
Ankrd44
Name: ankyrin repeat domain 44
Synonyms: E130014H08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329154
Homologene: 27547
Or1e19
Name: olfactory receptor family 1 subfamily E member 19
Synonyms: Olfr378, GA_x6K02T2P1NL-3586282-3585338, MOR135-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259026
Homologene: 74110
Car5b
Name: carbonic anhydrase 5b, mitochondrial
Synonyms: D730005F19Rik, 7330410H16Rik, CAVB
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 56078
HGNC: HGNC:1378
Homologene: 21413
Mcat
Name: malonyl CoA:ACP acyltransferase (mitochondrial)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223722
VEGA: 15
Homologene: 15511
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: D1Mgi1, 9230107O05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Vmn1r11
Name: vomeronasal 1 receptor 11
Synonyms: V1rc3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113860
Homologene: 128345
Abhd17a
Name: abhydrolase domain containing 17A
Synonyms: D10Bwg1364e, 1700013O15Rik, Fam108a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216169
Homologene: 50272
Serpinb5
Name: serine (or cysteine) peptidase inhibitor, clade B, member 5
Synonyms: Maspin, ovalbumin, 1110036M19Rik, Spi7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20724
HGNC: HGNC:8949
Homologene: 20580
Art2b
Name: ADP-ribosyltransferase 2b
Synonyms: Rt6-2, ART2.2, Rt-6, Rt6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11872
Homologene: 113756
Zfp768
Name: zinc finger protein 768
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233890
Homologene: 11650
Mup15
Name: major urinary protein 15
Synonyms: Gm2068
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100039150
Homologene: 74304
Mapk7
Name: mitogen-activated protein kinase 7
Synonyms: ERK5, b2b2346Clo, Erk5-T, big MAP kinase 1, BMK1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 23939
HGNC: HGNC:6880
Homologene: 2060
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 14,885,812 bp
  • T to C, chromosome 1 at 21,402,386 bp
  • G to T, chromosome 1 at 44,009,791 bp
  • A to G, chromosome 1 at 54,437,939 bp
  • T to A, chromosome 1 at 54,651,655 bp
  • C to A, chromosome 1 at 74,351,522 bp
  • A to T, chromosome 1 at 106,876,052 bp
  • A to T, chromosome 1 at 118,552,058 bp
  • A to T, chromosome 1 at 156,255,802 bp
  • A to T, chromosome 1 at 173,872,875 bp
  • A to T, chromosome 2 at 5,904,113 bp
  • T to A, chromosome 2 at 49,257,381 bp
  • T to C, chromosome 2 at 66,332,287 bp
  • T to C, chromosome 2 at 88,700,762 bp
  • A to T, chromosome 2 at 102,842,955 bp
  • C to T, chromosome 2 at 126,639,249 bp
  • A to T, chromosome 3 at 87,384,802 bp
  • A to G, chromosome 3 at 89,428,445 bp
  • A to T, chromosome 3 at 93,219,769 bp
  • A to T, chromosome 3 at 95,327,467 bp
  • T to C, chromosome 4 at 32,639,938 bp
  • T to A, chromosome 4 at 61,438,234 bp
  • T to A, chromosome 4 at 96,531,661 bp
  • T to C, chromosome 4 at 117,904,659 bp
  • A to G, chromosome 4 at 137,548,096 bp
  • T to A, chromosome 5 at 6,771,105 bp
  • T to A, chromosome 5 at 25,314,515 bp
  • T to C, chromosome 5 at 53,835,157 bp
  • G to A, chromosome 5 at 114,196,807 bp
  • T to A, chromosome 5 at 122,435,515 bp
  • T to C, chromosome 5 at 129,753,218 bp
  • T to A, chromosome 6 at 57,137,409 bp
  • A to G, chromosome 6 at 93,747,329 bp
  • T to C, chromosome 7 at 23,320,372 bp
  • A to T, chromosome 7 at 26,611,794 bp
  • A to G, chromosome 7 at 101,579,890 bp
  • G to A, chromosome 7 at 109,484,619 bp
  • T to A, chromosome 7 at 127,343,561 bp
  • A to T, chromosome 8 at 54,672,501 bp
  • T to C, chromosome 8 at 95,338,697 bp
  • T to C, chromosome 8 at 107,064,122 bp
  • T to A, chromosome 8 at 124,028,077 bp
  • T to A, chromosome 9 at 46,202,022 bp
  • C to A, chromosome 9 at 46,221,089 bp
  • A to G, chromosome 9 at 107,577,995 bp
  • A to G, chromosome 9 at 108,848,865 bp
  • A to C, chromosome 9 at 108,978,825 bp
  • A to G, chromosome 9 at 111,272,247 bp
  • T to A, chromosome 10 at 59,448,848 bp
  • A to G, chromosome 10 at 80,584,330 bp
  • C to T, chromosome 11 at 49,636,339 bp
  • A to C, chromosome 11 at 50,265,707 bp
  • T to C, chromosome 11 at 61,493,863 bp
  • T to C, chromosome 11 at 67,289,812 bp
  • T to A, chromosome 11 at 69,022,561 bp
  • T to A, chromosome 11 at 73,425,827 bp
  • T to C, chromosome 11 at 85,361,009 bp
  • C to T, chromosome 11 at 87,536,910 bp
  • A to G, chromosome 11 at 101,735,387 bp
  • T to A, chromosome 11 at 105,922,137 bp
  • G to T, chromosome 11 at 109,973,821 bp
  • G to A, chromosome 11 at 113,893,575 bp
  • A to G, chromosome 11 at 115,329,849 bp
  • A to T, chromosome 11 at 118,114,233 bp
  • G to C, chromosome 12 at 72,574,400 bp
  • T to C, chromosome 12 at 98,668,861 bp
  • T to A, chromosome 12 at 103,606,945 bp
  • T to C, chromosome 12 at 113,075,380 bp
  • T to C, chromosome 13 at 3,570,409 bp
  • A to G, chromosome 13 at 11,601,841 bp
  • C to T, chromosome 13 at 22,620,990 bp
  • T to A, chromosome 13 at 34,911,212 bp
  • G to T, chromosome 13 at 55,554,434 bp
  • A to G, chromosome 14 at 64,736,266 bp
  • T to C, chromosome 15 at 82,782,022 bp
  • G to A, chromosome 15 at 83,549,252 bp
  • T to C, chromosome 16 at 10,635,259 bp
  • T to C, chromosome 17 at 6,742,708 bp
  • T to C, chromosome 17 at 18,167,363 bp
  • C to T, chromosome 17 at 24,504,541 bp
  • C to A, chromosome 17 at 30,752,075 bp
  • C to T, chromosome 18 at 69,960,514 bp
  • T to A, chromosome 19 at 8,936,369 bp
  • G to T, chromosome 19 at 12,461,247 bp
  • T to C, chromosome 19 at 56,928,311 bp
  • T to A, chromosome X at 163,988,404 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1497 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039548-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.