Strain Name:
C57BL/6J-MtgxR1520Btlr/Mmmh
Stock Number:
039564-MU
Citation ID:
RRID:MMRRC_039564-MU
Other Names:
R1520 (G1), C57BL/6J-MtgxR1520Btlr
Major Collection:

Gene Information

Th
Name: tyrosine hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21823
Homologene: 307
Vldlr
Name: very low density lipoprotein receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 22359
Homologene: 443
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21828
Homologene: 20691
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, mDomino, p400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75560
Homologene: 38779
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, 1110051N18Rik, Zcwcc3, D16Jhu32e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 338467
Homologene: 32257
Tmem87b
Name: transmembrane protein 87B
Synonyms: 2610301K12Rik, 2810431I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72477
Homologene: 69513
Ezh2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: KMT6, Enx1h, Enx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14056
HGNC: HGNC:3527
Homologene: 37926
Tcf12
Name: transcription factor 12
Synonyms: HEB, REB, HTF4, HEBAlt, ALF1, ME1, bHLHb20, HTF-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21406
Homologene: 40774
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: 2700059D02Rik, nucling
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72565
VEGA: 9
Homologene: 74297
Wwox
Name: WW domain-containing oxidoreductase
Synonyms: 5330426P09Rik, 9030416C10Rik, WOX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 80707
Homologene: 56334
Srrt
Name: serrate RNA effector molecule homolog (Arabidopsis)
Synonyms: Ars2, 2810019G02Rik, Asr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83701
Homologene: 9298
Esyt2
Name: extended synaptotagmin-like protein 2
Synonyms: Fam62b, D12Ertd551e, 2410017M09Rik, 4921504I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 52635
VEGA: 12
Homologene: 32699
Chaf1a
Name: chromatin assembly factor 1, subunit A (p150)
Synonyms: CAF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27221
VEGA: 17
HGNC: HGNC:1910
Homologene: 4003
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 4921511H13Rik, 5730405K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207932
Homologene: 45941
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20624
Homologene: 3133
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, Ankyrin-G, Ankyrin-3, 2900054D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: Adprtl1, VPARP, C030027K23Rik, E230037B21Rik, VAULT3, PH5P, p193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Zfp317
Name: zinc finger protein 317
Synonyms: D230022C05Rik, KRAB9, Zfp75, Zfp67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244713
Homologene: 36389
Zap70
Name: zeta-chain (TCR) associated protein kinase
Synonyms: ZAP-70, TZK, Srk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22637
Homologene: 839
Sc5d
Name: sterol-C5-desaturase
Synonyms: A830073K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235293
VEGA: 9
Homologene: 5044
Eng
Name: endoglin
Synonyms: Endo, CD105
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13805
HGNC: HGNC:3349
Homologene: 92
Ppip5k2
Name: diphosphoinositol pentakisphosphate kinase 2
Synonyms: Hisppd1, Cfap160, Vip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227399
Homologene: 49409
Rag2
Name: recombination activating gene 2
Synonyms: Rag-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19374
HGNC: HGNC:9832
Homologene: 7507
Sv2b
Name: synaptic vesicle glycoprotein 2 b
Synonyms: A830038F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 64176
Homologene: 32236
Agpat3
Name: 1-acylglycerol-3-phosphate O-acyltransferase 3
Synonyms: LPAAT3, D10Jhu12e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 28169
HGNC: HGNC:326
Homologene: 10591
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Unc13b
Name: unc-13 homolog B
Synonyms: Munc13-2, Unc13h2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22249
Homologene: 31376
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Antxr2
Name: anthrax toxin receptor 2
Synonyms: CMG-2, cI-35, 2310046B19Rik, CMG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71914
Homologene: 43236
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229898
Homologene: 14183
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
V1rd19
Name: vomeronasal 1 receptor, D19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404287
Homologene: 104166
Abcb1b
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1B
Synonyms: Pgy-1, Mdr1, Abcb1, Mdr1b, mdr, Pgy1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18669
Homologene: 69084
Tmem273
Name: transmembrane protein 273
Synonyms: 1810011H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 69069
VEGA: 14
Homologene: 78635
Tdrd12
Name: tudor domain containing 12
Synonyms: 2410004F06Rik, ecat8, 2410070K17Rik, G1-476-14, EG434165, repro23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71981
Homologene: 87053
Vmn2r80
Name: vomeronasal 2, receptor 80
Synonyms: EG624765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 624765
Homologene: 83483
Corin
Name: corin, serine peptidase
Synonyms: Lrp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53419
Homologene: 4804
Fmo9
Name: flavin containing monooxygenase 9
Synonyms: 4831428F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240894
Homologene: 134192
Doxl1
Name: diamine oxidase-like protein 1
Synonyms: 1600015I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69761
Homologene: 79726
Srp54a
Name: signal recognition particle 54A
Synonyms: Srp54, 54K subunit of signal recognition particle, 54kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 24067
VEGA: 12
Homologene: 2362
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381293
Homologene: 8916
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: flamingo, Fmi1, Adgrc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76645
Homologene: 124481
Iqcc
Name: IQ motif containing C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230767
Homologene: 49526
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: Mamdc3, 1200011I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74762
Homologene: 17780
Rgr
Name: retinal G protein coupled receptor
Synonyms: RGR opsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 57811
VEGA: 14
HGNC: HGNC:9990
Homologene: 37709
Osbpl3
Name: oxysterol binding protein-like 3
Synonyms: 1200014M06Rik, 6720421I08Rik, ORP3, OSBP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 71720
Homologene: 49422
Pcgf5
Name: polycomb group ring finger 5
Synonyms: 9530023M17Rik, 0610009F02Rik, 1110054A01Rik, 5830443C21Rik, 5830406C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 76073
VEGA: 19
Homologene: 12632
Mcm8
Name: minichromosome maintenance 8 homologous recombination repair factor
Synonyms: 5730432L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66634
Homologene: 12001
Cyp3a11
Name: cytochrome P450, family 3, subfamily a, polypeptide 11
Synonyms: IIIAm1, Cyp3a, Pcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13112
HGNC: HGNC:2638
Homologene: 133568
Olfr1287
Name: olfactory receptor 1287
Synonyms: GA_x6K02T2Q125-72500603-72501520, MOR248-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257935
Serinc2
Name: serine incorporator 2
Synonyms: Tde2l, FKSG84, TDE2, 2310004K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230779
Homologene: 27797
Cyp4a32
Name: cytochrome P450, family 4, subfamily a, polypeptide 32
Synonyms: OTTMUSG00000008689
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100040843
HGNC: HGNC:2642
Homologene: 128044
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Plod3
Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Synonyms: lysyl hydroxylase 3, LH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26433
HGNC: HGNC:9083
Homologene: 843
Mylk4
Name: myosin light chain kinase family, member 4
Synonyms: EG238564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238564
Homologene: 66243
Tacc3
Name: transforming, acidic coiled-coil containing protein 3
Synonyms: Arnt interacting protein, Aint
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21335
Homologene: 81618
Frmpd4
Name: FERM and PDZ domain containing 4
Synonyms: PKAP1, LOC237234, Preso, Preso1, Pdzd10, Pdzk10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 333605
Homologene: 45843
Gm14685
Name: predicted gene 14685
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 574404
Homologene: 128534
Akr1c12
Name: aldo-keto reductase family 1, member C12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 622402
Homologene: 121208
Gpr65
Name: G-protein coupled receptor 65
Synonyms: Gpcr25, Dig1, TDAG8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 14744
VEGA: 12
HGNC: HGNC:4517
Homologene: 2675
Prkra
Name: protein kinase, interferon inducible double stranded RNA dependent activator
Synonyms: lear, PRK, RAX, Pact
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 23992
HGNC: HGNC:9438
Homologene: 2738
Rit1
Name: Ras-like without CAAX 1
Synonyms: Rit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19769
Homologene: 56003
Mutyh
Name: mutY DNA glycosylase
Synonyms: Mutyhbeta, Mutyha, Myh, 5730495A01Rik, Mutyhb, Mutyhc, Mutyhalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 70603
HGNC: HGNC:7527
Homologene: 8156
Preb
Name: prolactin regulatory element binding
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50907
HGNC: HGNC:9356
Homologene: 40877
Rhbdd2
Name: rhomboid domain containing 2
Synonyms: Usmg1, 0610011L13Rik, Rhbdl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 215160
Homologene: 32481
Igkv7-33
Name: immunoglobulin kappa chain variable 7-33
Synonyms: U29423
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243461
Jund
Name: jun D proto-oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16478
HGNC: HGNC:6206
Homologene: 3910
C1ql4
Name: complement component 1, q subcomponent-like 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239659
VEGA: 15
Homologene: 19354
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 36,770,955 bp
  • A to G, chromosome 1 at 97,734,955 bp
  • A to G, chromosome 1 at 136,503,324 bp
  • G to T, chromosome 1 at 166,667,455 bp
  • A to G, chromosome 2 at 32,672,941 bp
  • T to C, chromosome 2 at 76,639,278 bp
  • T to C, chromosome 2 at 76,817,048 bp
  • T to A, chromosome 2 at 82,980,714 bp
  • T to C, chromosome 2 at 101,630,131 bp
  • G to A, chromosome 2 at 111,449,274 bp
  • T to C, chromosome 2 at 128,839,256 bp
  • T to C, chromosome 2 at 132,839,455 bp
  • T to A, chromosome 3 at 88,729,313 bp
  • C to T, chromosome 3 at 96,651,738 bp
  • A to T, chromosome 3 at 142,508,014 bp
  • T to G, chromosome 4 at 43,261,674 bp
  • A to G, chromosome 4 at 115,614,652 bp
  • T to C, chromosome 4 at 116,817,552 bp
  • G to A, chromosome 4 at 129,616,969 bp
  • C to T, chromosome 4 at 130,260,750 bp
  • G to A, chromosome 5 at 8,814,768 bp
  • A to G, chromosome 5 at 30,958,524 bp
  • G to A, chromosome 5 at 33,664,860 bp
  • A to C, chromosome 5 at 72,330,895 bp
  • G to A, chromosome 5 at 97,960,692 bp
  • A to G, chromosome 5 at 110,691,778 bp
  • A to G, chromosome 5 at 114,201,940 bp
  • T to C, chromosome 5 at 135,643,019 bp
  • A to G, chromosome 5 at 136,991,311 bp
  • C to A, chromosome 5 at 137,298,766 bp
  • T to C, chromosome 5 at 145,862,453 bp
  • A to G, chromosome 6 at 47,551,910 bp
  • T to A, chromosome 6 at 48,931,297 bp
  • T to A, chromosome 6 at 50,346,431 bp
  • T to A, chromosome 6 at 70,059,148 bp
  • G to A, chromosome 7 at 24,003,198 bp
  • A to G, chromosome 7 at 24,919,704 bp
  • A to G, chromosome 7 at 35,523,932 bp
  • A to G, chromosome 7 at 75,157,329 bp
  • G to T, chromosome 7 at 142,893,200 bp
  • A to G, chromosome 8 at 70,699,274 bp
  • C to T, chromosome 8 at 114,712,133 bp
  • A to G, chromosome 8 at 117,046,159 bp
  • A to G, chromosome 9 at 19,647,848 bp
  • C to T, chromosome 9 at 42,258,650 bp
  • A to T, chromosome 9 at 60,871,381 bp
  • C to A, chromosome 9 at 71,883,106 bp
  • T to C, chromosome 9 at 108,848,658 bp
  • G to A, chromosome 10 at 69,885,129 bp
  • A to T, chromosome 10 at 78,288,023 bp
  • A to G, chromosome 10 at 79,194,760 bp
  • A to G, chromosome 10 at 80,008,830 bp
  • A to G, chromosome 11 at 102,839,440 bp
  • T to C, chromosome 12 at 55,257,569 bp
  • T to C, chromosome 12 at 98,275,175 bp
  • T to C, chromosome 12 at 116,342,258 bp
  • A to C, chromosome 13 at 4,276,299 bp
  • T to C, chromosome 13 at 32,712,838 bp
  • A to G, chromosome 13 at 92,769,609 bp
  • A to T, chromosome 14 at 32,805,126 bp
  • A to G, chromosome 14 at 37,044,715 bp
  • T to C, chromosome 14 at 56,598,406 bp
  • T to C, chromosome 15 at 99,087,667 bp
  • C to A, chromosome 16 at 90,774,745 bp
  • A to G, chromosome 16 at 93,844,241 bp
  • A to G, chromosome 17 at 29,846,519 bp
  • T to C, chromosome 17 at 56,047,302 bp
  • C to T, chromosome 19 at 27,240,543 bp
  • G to T, chromosome 19 at 27,247,066 bp
  • T to C, chromosome 19 at 36,442,841 bp
  • G to T, chromosome X at 73,127,655 bp
  • T to C, chromosome X at 167,492,953 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1520 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039564-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.