Strain Name:
C57BL/6J-MtgxR1536Btlr/Mmmh
Stock Number:
039575-MU
Citation ID:
RRID:MMRRC_039575-MU
Other Names:
R1536 (G1), C57BL/6J-MtgxR1536Btlr
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: SBF2, 4833411B01Rik, mMTMH1, B430219L04Rik, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Slc1a2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Synonyms: GLT1, MGLT1, Eaat2, 1700091C19Rik, GLT-1, 2900019G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20511
Homologene: 3075
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Mbtps1
Name: membrane-bound transcription factor peptidase, site 1
Synonyms: subtilisin/kexin isozyme-1, SKI-1, S1P, 0610038M03Rik, site-1 protease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56453
Homologene: 2808
Maco1
Name: macoilin 1
Synonyms: 9230118A01Rik, C61, 1110007C24Rik, Tmem57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66146
Homologene: 14449
Cwc27
Name: CWC27 spliceosome-associated protein
Synonyms: NY-CO-10, 3110009E13Rik, Sdccag10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67285
Homologene: 21192
Nudt5
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 53893
HGNC: HGNC:8052
Homologene: 5388
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Rps6kc1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: RPK118, B130003F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320119
Homologene: 8244
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, Drf1, Dia1, D18Wsu154e, mDia1, Diap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Eif4b
Name: eukaryotic translation initiation factor 4B
Synonyms: 2310046H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75705
VEGA: 15
HGNC: HGNC:3285
Homologene: 83162
Ergic1
Name: endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
Synonyms: 1200007D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67458
Homologene: 41667
Nav2
Name: neuron navigator 2
Synonyms: POMFIL2, Unc53H2, HELAD1, RAINB2, 5330421F07Rik, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78286
Homologene: 52330
Prom1
Name: prominin 1
Synonyms: AC133, CD133, Prom, 4932416E19Rik, Prom-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19126
HGNC: HGNC:9454
Homologene: 4390
Afap1
Name: actin filament associated protein 1
Synonyms: 9630044L16Rik, 2600003E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70292
Homologene: 11009
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Tiprl
Name: TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Synonyms: 1810011K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226591
Homologene: 7140
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226169
Homologene: 9006
Galnt3
Name: polypeptide N-acetylgalactosaminyltransferase 3
Synonyms: ppGaNTase-T3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14425
HGNC: HGNC:4125
Homologene: 55827
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: PC-1, NPP1, Npps, Pca-1, Pca, Ly-41, Pdnp1, twy, CD203c, E-NPP1, 4833416E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18605
HGNC: HGNC:3356
Homologene: 38151
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: FIC1, Ic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Prkaa2
Name: protein kinase, AMP-activated, alpha 2 catalytic subunit
Synonyms: 2310008I11Rik, AMPKalpha2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108079
HGNC: HGNC:9377
Homologene: 4551
Klra3
Name: killer cell lectin-like receptor, subfamily A, member 3
Synonyms: 5E6, Ly49C, Nk-2, Ly49c, NK-2.1, Nk2.1, Nk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16634
Homologene: 110821
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668940
Homologene: 66117
Vmn2r3
Name: vomeronasal 2, receptor 3
Synonyms: EG637004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 637004
Entpd5
Name: ectonucleoside triphosphate diphosphohydrolase 5
Synonyms: mNTPase, NTPDase-5, ER-UDPase, NTPDase5, Cd39l4, Pcph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12499
HGNC: HGNC:3367
Homologene: 37457
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: 0710001E20Rik, LGL3, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78808
Homologene: 16402
4930458L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Stk35
Name: serine/threonine kinase 35
Synonyms: CLP-36 interacting kinase, CLIK1, 1700054C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67333
Homologene: 15441
Gjd4
Name: gap junction protein, delta 4
Synonyms: connexin 39, Cx39, 9430022F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225152
VEGA: 18
Homologene: 17692
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232400
Homologene: 45969
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: NG2, AN2, 4732461B14Rik, Cspg4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Tifab
Name: TRAF-interacting protein with forkhead-associated domain, family member B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 212937
VEGA: 13
Homologene: 27087
Erich6
Name: glutamate rich 6
Synonyms: 4932431H17Rik, Fam194a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 545527
Homologene: 65043
Adamts19
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Zfp944
Name: zinc finger protein 944
Synonyms: 6330416L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 319615
VEGA: 17
Homologene: 133237
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232367
Ercc6l2
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2
Synonyms: 1700019D06Rik, 9330134C04Rik, 0610007P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76251
Homologene: 32564
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Olfr272
Name: olfactory receptor 272
Synonyms: GA_x6K02T2N78B-7084885-7085844, MOR262-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258836
Homologene: 17409
Gm20382
Name: predicted gene, 20382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Txndc17
Name: thioredoxin domain containing 17
Synonyms: 4831443O22Rik, TRP14, D11Ertd672e, Txnl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 52700
Homologene: 41683
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Gpc5
Name: glypican 5
Synonyms: A230034F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 103978
HGNC: HGNC:4453
Homologene: 3285
Cbll1
Name: Casitas B-lineage lymphoma-like 1
Synonyms: c-Cbl-like, Hakai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104836
Homologene: 11734
Trim43b
Name: tripartite motif-containing 43B
Synonyms: Gm8269
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 666747
Homologene: 105432
Man2b2
Name: mannosidase 2, alpha B2
Synonyms: 135 kDa alpha-D-mannosidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17160
Homologene: 7411
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19153
Homologene: 76542
4930590J08Rik
Name: RIKEN cDNA 4930590J08 gene
Synonyms: LOC381798
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381798
Homologene: 49985
Cblc
Name: Casitas B-lineage lymphoma c
Synonyms: Cbl3, 2310079L19Rik, 2310076I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80794
Homologene: 8108
Plcxd3
Name: phosphatidylinositol-specific phospholipase C, X domain containing 3
Synonyms: B130016O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239318
Homologene: 45574
Tlr12
Name: toll-like receptor 12
Synonyms: LOC384059, Tlr11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 384059
Homologene: 135964
Cd200r4
Name: CD200 receptor 4
Synonyms: F630107N04Rik, MCD200RLa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239849
Homologene: 45557
Cox7a2
Name: cytochrome c oxidase subunit 7A2
Synonyms: COX7AL, Cox7a3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12866
VEGA: 9
HGNC: HGNC:2288
Homologene: 36082
CAAA01077335.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
2310003L06Rik
Name: RIKEN cDNA 2310003L06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Chmp4c
Name: charged multivesicular body protein 4C
Synonyms: 2210015K02Rik, 2010012P02Rik, 2310010I16Rik, Snf7-3, chromatin modifying protein 4C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66371
Homologene: 23544
Gm5611
Name: predicted gene 5611
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 434373
VEGA: 9
Ear1
Name: eosinophil-associated, ribonuclease A family, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13586
Homologene: 40596
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,260,372 bp
  • A to G, chromosome 1 at 165,228,406 bp
  • C to T, chromosome 1 at 190,871,768 bp
  • T to A, chromosome 2 at 5,863,567 bp
  • A to G, chromosome 2 at 53,105,537 bp
  • A to T, chromosome 2 at 66,084,206 bp
  • A to T, chromosome 2 at 102,777,510 bp
  • T to C, chromosome 2 at 129,811,235 bp
  • A to T, chromosome 2 at 155,634,071 bp
  • G to T, chromosome 3 at 10,389,684 bp
  • A to T, chromosome 3 at 58,626,598 bp
  • T to A, chromosome 3 at 64,275,117 bp
  • A to G, chromosome 4 at 52,911,260 bp
  • T to A, chromosome 4 at 105,075,450 bp
  • A to G, chromosome 4 at 128,617,752 bp
  • A to G, chromosome 4 at 134,804,507 bp
  • C to A, chromosome 5 at 35,974,491 bp
  • T to C, chromosome 5 at 36,820,927 bp
  • T to A, chromosome 5 at 44,018,353 bp
  • A to T, chromosome 5 at 87,970,665 bp
  • C to T, chromosome 5 at 131,487,463 bp
  • A to T, chromosome 5 at 137,210,081 bp
  • A to G, chromosome 6 at 91,917,035 bp
  • T to C, chromosome 6 at 124,200,690 bp
  • A to T, chromosome 6 at 128,547,233 bp
  • G to C, chromosome 6 at 130,333,144 bp
  • G to A, chromosome 7 at 19,792,244 bp
  • A to G, chromosome 7 at 27,517,258 bp
  • C to A, chromosome 7 at 49,545,934 bp
  • T to C, chromosome 7 at 110,378,043 bp
  • A to T, chromosome 8 at 119,546,125 bp
  • T to C, chromosome 9 at 9,976,316 bp
  • G to A, chromosome 9 at 17,030,607 bp
  • T to C, chromosome 9 at 56,890,044 bp
  • T to A, chromosome 9 at 79,758,581 bp
  • A to T, chromosome 9 at 89,085,358 bp
  • T to A, chromosome 10 at 9,838,092 bp
  • T to A, chromosome 10 at 24,641,834 bp
  • A to G, chromosome 10 at 80,014,230 bp
  • T to A, chromosome 11 at 69,903,426 bp
  • C to A, chromosome 11 at 72,207,707 bp
  • T to C, chromosome 12 at 31,487,856 bp
  • G to A, chromosome 12 at 84,382,295 bp
  • A to G, chromosome 13 at 56,176,288 bp
  • C to A, chromosome 13 at 63,824,871 bp
  • A to T, chromosome 13 at 64,921,382 bp
  • A to G, chromosome 13 at 104,797,306 bp
  • T to A, chromosome 14 at 43,819,126 bp
  • T to A, chromosome 14 at 115,399,250 bp
  • T to C, chromosome 15 at 4,516,611 bp
  • T to C, chromosome 15 at 35,875,566 bp
  • G to C, chromosome 15 at 98,600,007 bp
  • T to C, chromosome 15 at 102,093,728 bp
  • A to T, chromosome 16 at 44,833,049 bp
  • G to T, chromosome 17 at 22,339,716 bp
  • T to C, chromosome 17 at 26,641,706 bp
  • T to A, chromosome 18 at 9,280,569 bp
  • A to G, chromosome 18 at 37,896,093 bp
  • A to T, chromosome 18 at 59,052,615 bp
  • C to T, chromosome 18 at 64,545,264 bp
  • T to C, chromosome 19 at 17,711,903 bp
  • T to C, chromosome 19 at 46,071,526 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1536 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039575-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.