Strain Name:
C57BL/6J-MtgxR1549Btlr/Mmmh
Stock Number:
039588-MU
Citation ID:
RRID:MMRRC_039588-MU
Other Names:
R1549 (G1), C57BL/6J-MtgxR1549Btlr
Major Collection:

Gene Information

Ccnd1
Name: cyclin D1
Synonyms: CycD1, cD1, Cyl-1, PRAD1, bcl-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12443
HGNC: HGNC:1582
Homologene: 1334
Ddc
Name: dopa decarboxylase
Synonyms: Aadc, aromatic L-amino acid decarboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13195
HGNC: HGNC:2719
Homologene: 618
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68926
Homologene: 73649
Manba
Name: mannosidase, beta A, lysosomal
Synonyms: B930014J03Rik, Bmn, 2410030O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 110173
HGNC: HGNC:6831
Homologene: 4317
Strn4
Name: striatin, calmodulin binding protein 4
Synonyms: ZIN, zinedin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 97387
Homologene: 8378
Phf3
Name: PHD finger protein 3
Synonyms: 2310061N19Rik, AU020177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213109
HGNC: HGNC:8921
Homologene: 9040
Gpbp1
Name: GC-rich promoter binding protein 1
Synonyms: 1700034P14Rik, D230035M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 73274
Homologene: 11292
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, D630005A10Rik, A430040A19Rik, Bruce, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Eif4b
Name: eukaryotic translation initiation factor 4B
Synonyms: 2310046H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75705
VEGA: 15
HGNC: HGNC:3285
Homologene: 83162
Tbcd
Name: tubulin-specific chaperone d
Synonyms: 2310057L06Rik, A030005L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108903
Homologene: 4368
Pspc1
Name: paraspeckle protein 1
Synonyms: 5730470C09Rik, PSP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66645
Homologene: 10108
Eef2
Name: eukaryotic translation elongation factor 2
Synonyms: Ef-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13629
VEGA: 10
HGNC: HGNC:3214
Homologene: 134867
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, Ankyrin-G, Ankyrin-3, 2900054D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Stim2
Name: stromal interaction molecule 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 116873
Homologene: 32490
Atg16l1
Name: autophagy related 16-like 1 (S. cerevisiae)
Synonyms: WDR30, 1500009K01Rik, APG16L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77040
Homologene: 41786
Pou4f1
Name: POU domain, class 4, transcription factor 1
Synonyms: Brn-3, E130119J07Rik, Brn3a, Brn-3.0, Brn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18996
HGNC: HGNC:9218
Homologene: 21255
Ap5m1
Name: adaptor-related protein complex 5, mu 1 subunit
Synonyms: Mudeng, 4932432K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74385
VEGA: 14
Homologene: 10081
Camta1
Name: calmodulin binding transcription activator 1
Synonyms: 2310058O09Rik, 1810059M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100072
Homologene: 18942
Ptk7
Name: PTK7 protein tyrosine kinase 7
Synonyms: chz, mPTK7/CCK4, 8430404F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71461
VEGA: 17
HGNC: HGNC:9618
Homologene: 43672
Gm2381
Name: predicted gene 2381
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100039706
HGNC: null
Homologene: null
Galnt14
Name: polypeptide N-acetylgalactosaminyltransferase 14
Synonyms: 0610033M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71685
Homologene: 56997
Rab23
Name: RAB23, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19335
Homologene: 7503
Nck1
Name: non-catalytic region of tyrosine kinase adaptor protein 1
Synonyms: Nck, 6330586M15Rik, D230010O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17973
HGNC: HGNC:7664
Homologene: 38148
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71409
Homologene: 70871
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Mapk3
Name: mitogen-activated protein kinase 3
Synonyms: p44mapk, Mtap2k, p44erk1, Prkm3, Esrk1, Erk-1, p44 MAP kinase, Erk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26417
HGNC: HGNC:6877
Homologene: 55682
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Cfap58
Name: cilia and flagella associated protein 58
Synonyms: Ccdc147, LOC381229
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 381229
VEGA: 19
Homologene: 77312
Iigp1
Name: interferon inducible GTPase 1
Synonyms: 2900074L10Rik, Irga6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 60440
VEGA: 18
HGNC: null
Homologene: null
Bcl11b
Name: B cell leukemia/lymphoma 11B
Synonyms: CTIP2, B630002E05Rik, 9130430L19Rik, COUP-TF interacting protein 2, Rit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 58208
Homologene: 10974
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 667060
HGNC: null
Homologene: null
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241919
Homologene: 76320
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71824
HGNC: null
Homologene: null
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: 6430601K09Rik, DPRP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269109
Homologene: 41400
Zfp217
Name: zinc finger protein 217
Synonyms: 4933431C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228913
Homologene: 4757
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clcn4-2, Clc4-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: Mamdc3, 1200011I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 74762
Homologene: 17780
Olfr412
Name: olfactory receptor 412
Synonyms: GA_x6K02T2P1NL-4500587-4501525, MOR127-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258153
HGNC: HGNC:8183
Homologene: 37634
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: Bpag, BPAg2, Bpag2, BP180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Ctif
Name: CBP80/20-dependent translation initiation factor
Synonyms: Gm672, LOC269037
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 269037
VEGA: 18
Homologene: 56682
Eif2b4
Name: eukaryotic translation initiation factor 2B, subunit 4 delta
Synonyms: Eif2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13667
HGNC: HGNC:3260
Homologene: 5976
Tmed3
Name: transmembrane p24 trafficking protein 3
Synonyms: 1200002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66111
Homologene: 7213
Pabpc1l
Name: poly(A) binding protein, cytoplasmic 1-like
Synonyms: ePAB, 1810053B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381404
Homologene: 77989
Klk1b26
Name: kallikrein 1-related petidase b26
Synonyms: Egfbp2, Klk26, mGK-26, EGF-BP type B, PRECE-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16618
HGNC: HGNC:6364
Homologene: 68141
Usp16
Name: ubiquitin specific peptidase 16
Synonyms: 6330514E22Rik, 2810483I07Rik, UBP-M, 1200004E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74112
Homologene: 38183
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 627569
HGNC: null
Homologene: 129606
Mdfic
Name: MyoD family inhibitor domain containing
Synonyms: Kdt1, clone 1.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16543
Homologene: 18404
Nek5
Name: NIMA (never in mitosis gene a)-related expressed kinase 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330721
HGNC: HGNC:7748
Homologene: 87952
Cyp2c69
Name: cytochrome P450, family 2, subfamily c, polypeptide 69
Synonyms: AI098658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 100043108
VEGA: 19
HGNC: null
Homologene: 74936
Kcns3
Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Synonyms: D12Ertd137e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238076
VEGA: 12
HGNC: HGNC:6302
Homologene: 20518
Zswim2
Name: zinc finger SWIM-type containing 2
Synonyms: MEX, 1700025P14Rik, 4933437F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71861
Homologene: 32689
Olfr1369-ps1
Name: olfactory receptor 1369, pseudogene 1
Synonyms: MOR256-31, GA_x6K02T2QHY8-12126170-12125935
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 404504
HGNC: HGNC:8281
Homologene: null
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: TRAMD2, PAT3, tramdorin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215332
Homologene: 76175
Gpr162
Name: G protein-coupled receptor 162
Synonyms: Grca, A-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14788
Homologene: 8400
Gm14409
Name: predicted gene 14409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: null
HGNC: null
Homologene: null
Lime1
Name: Lck interacting transmembrane adaptor 1
Synonyms: 2810038K19Rik, LIME
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72699
Homologene: 56785
Vmn2r31
Name: vomeronasal 2, receptor 31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100042591
HGNC: null
Homologene: 113703
Trav16d-dv11
Name: T cell receptor alpha variable 16D-DV11
Synonyms: ENSMUSG00000072535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 547329
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 30,804,842 bp
  • A to G, chromosome 1 at 33,738,297 bp
  • A to G, chromosome 1 at 87,774,188 bp
  • T to A, chromosome 1 at 123,341,380 bp
  • A to G, chromosome 2 at 53,105,537 bp
  • G to T, chromosome 2 at 83,923,748 bp
  • G to T, chromosome 2 at 164,037,171 bp
  • A to C, chromosome 2 at 170,114,470 bp
  • T to C, chromosome 2 at 177,265,585 bp
  • A to G, chromosome 2 at 181,383,376 bp
  • T to C, chromosome 3 at 31,224,118 bp
  • G to T, chromosome 3 at 64,504,000 bp
  • A to T, chromosome 3 at 124,416,792 bp
  • A to G, chromosome 3 at 135,544,806 bp
  • C to T, chromosome 4 at 41,199,872 bp
  • A to G, chromosome 4 at 151,586,463 bp
  • T to C, chromosome 5 at 31,192,921 bp
  • G to A, chromosome 5 at 54,105,325 bp
  • T to G, chromosome 5 at 109,092,830 bp
  • G to T, chromosome 6 at 15,799,845 bp
  • C to T, chromosome 6 at 124,860,088 bp
  • A to G, chromosome 7 at 7,291,682 bp
  • G to A, chromosome 7 at 7,387,199 bp
  • C to G, chromosome 7 at 16,837,836 bp
  • T to A, chromosome 7 at 42,822,401 bp
  • C to T, chromosome 7 at 44,016,402 bp
  • A to T, chromosome 7 at 126,763,512 bp
  • T to G, chromosome 7 at 144,937,336 bp
  • T to C, chromosome 8 at 22,078,588 bp
  • A to C, chromosome 9 at 89,699,945 bp
  • T to A, chromosome 9 at 100,497,872 bp
  • A to G, chromosome 9 at 108,955,966 bp
  • A to T, chromosome 10 at 70,001,982 bp
  • CCC to CCCC, chromosome 10 at 81,178,768 bp
  • A to G, chromosome 11 at 11,846,656 bp
  • A to G, chromosome 11 at 55,142,770 bp
  • A to G, chromosome 11 at 74,365,250 bp
  • A to G, chromosome 11 at 121,560,753 bp
  • T to C, chromosome 12 at 11,092,083 bp
  • T to A, chromosome 12 at 107,917,163 bp
  • T to C, chromosome 13 at 21,116,118 bp
  • G to T, chromosome 13 at 111,436,579 bp
  • G to T, chromosome 14 at 49,078,935 bp
  • A to G, chromosome 14 at 53,047,342 bp
  • T to G, chromosome 14 at 56,748,941 bp
  • T to C, chromosome 14 at 104,467,640 bp
  • T to C, chromosome 15 at 102,093,728 bp
  • A to G, chromosome 16 at 52,033,010 bp
  • G to T, chromosome 16 at 87,464,834 bp
  • G to A, chromosome 17 at 29,837,998 bp
  • T to C, chromosome 17 at 46,572,652 bp
  • A to G, chromosome 17 at 73,525,313 bp
  • A to G, chromosome 17 at 74,662,742 bp
  • G to A, chromosome 18 at 60,389,876 bp
  • C to A, chromosome 18 at 75,565,025 bp
  • A to T, chromosome 19 at 39,842,986 bp
  • C to T, chromosome 19 at 47,648,910 bp
  • G to A, chromosome 19 at 47,986,430 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1549 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039588-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.