Strain Name:
C57BL/6J-MtgxR1591Btlr/Mmmh
Stock Number:
039628-MU
Citation ID:
RRID:MMRRC_039628-MU
Other Names:
R1591 (G1), C57BL/6J-MtgxR1591Btlr
Major Collection:

Gene Information

Camkk2
Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Synonyms: 6330570N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207565
HGNC: HGNC:1470
Homologene: 32756
Fzr1
Name: fizzy and cell division cycle 20 related 1
Synonyms: Fyr, Cdh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56371
Homologene: 9444
Sdf2
Name: stromal cell derived factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20316
Homologene: 5045
Zfp113
Name: zinc finger protein 113
Synonyms: 4732456B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56314
Homologene: 50027
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Flt-2, Fgfr-1, Hspy, Eask, FGFR-I, Fr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Bub3
Name: BUB3 mitotic checkpoint protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12237
HGNC: HGNC:1151
Homologene: 3470
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Smg1
Name: SMG1 nonsense mediated mRNA decay associated PI3K related kinase
Synonyms: C130002K18Rik, 5430435M13Rik, 2610207I05Rik, SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233789
Homologene: 56697
Ogdh
Name: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Synonyms: alpha-ketoglutarate dehydrogenase, 2210412K19Rik, 2210403E04Rik, d1401
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18293
HGNC: HGNC:8124
Homologene: 55662
Ppp2ca
Name: protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
Synonyms: PP2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19052
HGNC: HGNC:9299
Homologene: 37660
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233532
Homologene: 41142
Acvr1b
Name: activin A receptor, type 1B
Synonyms: ActR-IB, Acvrlk4, SKR2, ActRIB, Alk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11479
HGNC: HGNC:172
Homologene: 20906
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100019
Homologene: 39689
Zfp26
Name: zinc finger protein 26
Synonyms: mkr-3, Zfp-26, 5033428C05Rik, Zfp70, KRAB15, Zfp81-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22688
Homologene: 52318
Osbpl11
Name: oxysterol binding protein-like 11
Synonyms: ORP-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106326
Homologene: 23385
Tnfrsf21
Name: tumor necrosis factor receptor superfamily, member 21
Synonyms: DR6, Death receptor 6, TR7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 94185
VEGA: 17
Homologene: 8696
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 277939
Homologene: 19524
Slc41a3
Name: solute carrier family 41, member 3
Synonyms: SLC41A1-L2, 1010001P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71699
Homologene: 23052
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: 6330512O03Rik, 2310038O07Rik, D10Ertd516e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71902
Homologene: 10202
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Lman1l
Name: lectin, mannose-binding 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235416
HGNC: HGNC:6632
Homologene: 11047
Tgfbr1
Name: transforming growth factor, beta receptor I
Synonyms: TbetaR-I, TbetaRI, ALK5, Alk-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21812
Homologene: 3177
Tes
Name: testin LIM domain protein
Synonyms: Tes2, Tes1, testin2, testin, D6Ertd352e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21753
Homologene: 41051
Cox6b1
Name: cytochrome c oxidase, subunit 6B1
Synonyms: 2010000G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 110323
HGNC: HGNC:2280
Homologene: 39658
Exosc10
Name: exosome component 10
Synonyms: PM/Scl-100, PM-Scl, RRP6, p4, p3, p2, Pmscl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50912
HGNC: HGNC:9138
Homologene: 31105
Slc25a27
Name: solute carrier family 25, member 27
Synonyms: D530043E16Rik, Ucp4, 3632410G24Rik, 9430092A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74011
VEGA: 17
Homologene: 12523
Rufy1
Name: RUN and FYVE domain containing 1
Synonyms: Rabip4, 3000002E04Rik, ZFYVE12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216724
Homologene: 23522
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229473
Homologene: 9057
Caprin2
Name: caprin family member 2
Synonyms: Eeg1, C1qdc1, RNG140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232560
Homologene: 11393
Zfp870
Name: zinc finger protein 870
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240066
VEGA: 17
Homologene: 48189
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: MDHC7, E030034C22Rik, B230373P09Rik, Dnahc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Lrp3
Name: low density lipoprotein receptor-related protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 435965
HGNC: HGNC:6695
Homologene: 1745
Ruvbl2
Name: RuvB-like protein 2
Synonyms: p47, mp47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20174
Homologene: 4856
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: 1810045E08Rik, MCCalpha, MCCA, 2310058B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Unc13b
Name: unc-13 homolog B
Synonyms: Unc13h2, Munc13-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18705
HGNC: HGNC:8973
Homologene: 3362
Olfr901
Name: olfactory receptor 901
Synonyms: GA_x6K02T2PVTD-32123032-32123967, MOR162-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258028
VEGA: 9
Homologene: 79399
Il11ra1
Name: interleukin 11 receptor, alpha chain 1
Synonyms: NR1, Il11ra, Il-11ra-alpha, Il-11ra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16157
HGNC: HGNC:5967
Homologene: 88705
Krt6a
Name: keratin 6A
Synonyms: mK6[a], MK6a, Krt2-6c, Krt2-6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16687
VEGA: 15
Homologene: 136794
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Asns
Name: asparagine synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 27053
HGNC: HGNC:753
Homologene: 69113
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241919
Homologene: 76320
Tifab
Name: TRAF-interacting protein with forkhead-associated domain, family member B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 212937
VEGA: 13
Homologene: 27087
Cdh4
Name: cadherin 4
Synonyms: Rcad, R-cadherin, R-Cadh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Cdh24
Name: cadherin-like 24
Synonyms: cadherin 14-like, EY-cadherin, 1700040A22Rik, ENSMUSG00000022188
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239096
VEGA: 14
Homologene: 56951
Mrps2
Name: mitochondrial ribosomal protein S2
Synonyms: 1500019M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 118451
Homologene: 99837
Kcng1
Name: potassium voltage-gated channel, subfamily G, member 1
Synonyms: OTTMUSG00000016048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241794
HGNC: HGNC:6248
Homologene: 20515
Olfr356
Name: olfactory receptor 356
Synonyms: GA_x6K02T2NLDC-33631647-33632594, MOR134-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258617
Homologene: 85948
St6galnac1
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Synonyms: ST6GalNAc I, Siat7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20445
Homologene: 7937
Mmrn1
Name: multimerin 1
Synonyms: 4921530G03Rik, Emilin4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70945
HGNC: HGNC:7178
Homologene: 49134
Pacsin2
Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: Syndapin II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 23970
VEGA: 15
HGNC: HGNC:8571
Homologene: 21414
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: 5031409J19Rik, Gpr110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77596
Homologene: 124643
Kif19a
Name: kinesin family member 19A
Synonyms: N-8 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 286942
Homologene: 17709
Adam6b
Name: a disintegrin and metallopeptidase domain 6B
Synonyms: 4930523C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238405
Homologene: 128362
Fap
Name: fibroblast activation protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14089
HGNC: HGNC:3590
Homologene: 48282
B3galt4
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
Synonyms: Gal-T2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54218
HGNC: HGNC:919
Homologene: 2805
Ecm1
Name: extracellular matrix protein 1
Synonyms: p85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13601
HGNC: HGNC:3153
Homologene: 3260
Pcdhb17
Name: protocadherin beta 17
Synonyms: Pcdhb16, PcdhbQ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93888
Homologene: 81881
Olfr484
Name: olfactory receptor 484
Synonyms: GA_x6K02T2PBJ9-10454128-10453163, MOR204-16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258492
Homologene: 36987
Kcna3
Name: potassium voltage-gated channel, shaker-related subfamily, member 3
Synonyms: Kv1.3, Kca1-3, Mk-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 16491
HGNC: HGNC:6221
Homologene: 128570
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78774
Lrrc63
Name: leucine rich repeat containing 63
Synonyms: 4921509B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70859
Homologene: 52823
Abraxas1
Name: BRCA1 A complex subunit
Synonyms: 5630400M01Rik, 3830405G04Rik, Ccdc98, Fam175a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70681
Homologene: 16376
Pate7
Name: prostate and testis expressed 7
Synonyms: Gm17727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100312986
Homologene: 129804
Arf3
Name: ADP-ribosylation factor 3
Synonyms: 5430400P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11842
HGNC: HGNC:654
Homologene: 68195
Rdh12
Name: retinol dehydrogenase 12
Synonyms: A930033N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77974
Homologene: 110830
Olfr147
Name: olfactory receptor 147
Synonyms: M3, MOR164-1, GA_x6K02T2PVTD-32098059-32099003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258869
VEGA: 9
Homologene: 128279
Olfr612
Name: olfactory receptor 612
Synonyms: GA_x6K02T2PBJ9-6251685-6250741, MOR15-3, EG545985
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 545985
Homologene: 79675
Grap2
Name: GRB2-related adaptor protein 2
Synonyms: Gads, Grb2-related adaptor downstream of Sch, GRID, GRAP-2, GrbX, GRB2L, Grf40, P38, Mona, GrpL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17444
VEGA: 15
HGNC: HGNC:4563
Homologene: 21007
Atp6v0d1
Name: ATPase, H+ transporting, lysosomal V0 subunit D1
Synonyms: Ac39, Atp6d, P39, Vma6, lysosomal 38kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11972
Homologene: 3444
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 136,149,317 bp
  • C to T, chromosome 2 at 28,469,488 bp
  • C to A, chromosome 2 at 36,937,978 bp
  • T to C, chromosome 2 at 62,553,857 bp
  • T to C, chromosome 2 at 76,776,045 bp
  • A to G, chromosome 2 at 146,145,458 bp
  • T to C, chromosome 2 at 168,268,710 bp
  • T to C, chromosome 2 at 179,886,864 bp
  • A to C, chromosome 3 at 31,237,449 bp
  • C to T, chromosome 3 at 35,989,857 bp
  • A to G, chromosome 3 at 83,940,889 bp
  • G to A, chromosome 3 at 95,735,963 bp
  • A to T, chromosome 3 at 107,037,029 bp
  • T to C, chromosome 4 at 32,700,092 bp
  • T to A, chromosome 4 at 41,766,200 bp
  • T to A, chromosome 4 at 43,244,747 bp
  • G to T, chromosome 4 at 47,403,471 bp
  • C to T, chromosome 4 at 113,999,454 bp
  • T to A, chromosome 4 at 148,568,383 bp
  • T to C, chromosome 5 at 41,819,220 bp
  • A to G, chromosome 5 at 57,720,422 bp
  • G to T, chromosome 5 at 100,809,639 bp
  • A to T, chromosome 5 at 114,203,423 bp
  • A to G, chromosome 5 at 122,757,558 bp
  • T to C, chromosome 5 at 138,151,197 bp
  • T to C, chromosome 6 at 7,678,007 bp
  • A to G, chromosome 6 at 17,097,442 bp
  • A to T, chromosome 6 at 60,944,771 bp
  • C to T, chromosome 6 at 73,076,600 bp
  • A to C, chromosome 6 at 90,633,695 bp
  • G to A, chromosome 6 at 139,748,178 bp
  • A to T, chromosome 6 at 148,873,108 bp
  • A to G, chromosome 7 at 30,617,172 bp
  • A to G, chromosome 7 at 35,202,365 bp
  • C to T, chromosome 7 at 45,424,711 bp
  • T to A, chromosome 7 at 97,639,313 bp
  • C to A, chromosome 7 at 100,395,315 bp
  • T to G, chromosome 7 at 103,539,067 bp
  • T to A, chromosome 7 at 108,124,364 bp
  • T to C, chromosome 7 at 118,156,919 bp
  • T to C, chromosome 7 at 131,561,608 bp
  • T to A, chromosome 8 at 15,900,710 bp
  • G to A, chromosome 8 at 25,572,720 bp
  • A to G, chromosome 8 at 90,983,538 bp
  • A to G, chromosome 8 at 105,531,007 bp
  • T to C, chromosome 9 at 20,437,625 bp
  • T to C, chromosome 9 at 35,776,656 bp
  • A to G, chromosome 9 at 38,402,936 bp
  • A to T, chromosome 9 at 38,430,411 bp
  • C to T, chromosome 9 at 57,615,802 bp
  • T to C, chromosome 9 at 95,945,385 bp
  • C to T, chromosome 10 at 81,370,367 bp
  • G to T, chromosome 10 at 119,211,869 bp
  • C to T, chromosome 10 at 127,605,606 bp
  • T to C, chromosome 11 at 6,349,384 bp
  • G to A, chromosome 11 at 50,394,928 bp
  • T to C, chromosome 11 at 52,099,089 bp
  • A to G, chromosome 11 at 78,254,993 bp
  • A to C, chromosome 11 at 114,789,231 bp
  • A to T, chromosome 11 at 116,765,863 bp
  • A to T, chromosome 12 at 79,211,504 bp
  • A to T, chromosome 12 at 113,489,832 bp
  • T to A, chromosome 13 at 56,176,351 bp
  • G to T, chromosome 14 at 31,272,332 bp
  • T to C, chromosome 14 at 54,636,342 bp
  • T to A, chromosome 14 at 75,125,892 bp
  • C to T, chromosome 14 at 78,908,230 bp
  • A to T, chromosome 15 at 80,648,448 bp
  • T to C, chromosome 15 at 83,385,051 bp
  • T to C, chromosome 15 at 98,742,788 bp
  • G to T, chromosome 15 at 101,194,024 bp
  • A to T, chromosome 15 at 101,692,357 bp
  • A to C, chromosome 16 at 33,209,983 bp
  • C to T, chromosome 17 at 32,884,016 bp
  • G to A, chromosome 17 at 33,950,839 bp
  • T to A, chromosome 17 at 43,085,374 bp
  • T to C, chromosome 17 at 43,310,981 bp
  • A to G, chromosome 17 at 43,653,424 bp
  • T to C, chromosome 18 at 37,485,825 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1591 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039628-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.