Strain Name:
C57BL/6J-MtgxR1607Btlr/Mmmh
Stock Number:
039644-MU
Citation ID:
RRID:MMRRC_039644-MU
Other Names:
R1607 (G1), C57BL/6J-MtgxR1607Btlr
Major Collection:

Strain Information

Ldb2
Name: LIM domain binding 2
Synonyms: CLIM-1b, CLP-36, CLIM-1a, CLIM1, Ldb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16826
HGNC: HGNC:6533
Homologene: 989
Enah
Name: ENAH actin regulator
Synonyms: Ndpp1, Mena
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13800
Homologene: 134005
Pkp4
Name: plakophilin 4
Synonyms: p0071, 5031422I09Rik, 9430019K17Rik, Armrp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Ubap2
Name: ubiquitin-associated protein 2
Synonyms: 1190005K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68926
Homologene: 73649
Clasp1
Name: CLIP associating protein 1
Synonyms: CLASP1alpha, B130045P17Rik, CLASP1, 5730583A19Rik, 1700030C23Rik, mCLASP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76707
Homologene: 41024
Cenpv
Name: centromere protein V
Synonyms: Prr6, 3110013H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73139
Homologene: 42965
Slc37a1
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 1
Synonyms: G3PP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224674
VEGA: 17
Homologene: 70486
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: repro8, 1500002J22Rik, G1-419-52, 4930523M17Rik, eIF4GII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Kif11
Name: kinesin family member 11
Synonyms: Kifl1, Knsl1, Eg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16551
VEGA: 19
HGNC: HGNC:6388
Homologene: 3322
Ctc1
Name: CTS telomere maintenance complex component 1
Synonyms: 1500010J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68964
Homologene: 11830
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227446
Homologene: 10834
Zc3h11a
Name: zinc finger CCCH type containing 11A
Synonyms: 5730454B08Rik, 1110003F06Rik, G630041M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70579
Homologene: 8888
Dvl2
Name: dishevelled segment polarity protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13543
HGNC: HGNC:3086
Homologene: 20927
Nup133
Name: nucleoporin 133
Synonyms: mermaid, 4832420O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234865
Homologene: 32402
Polr3b
Name: polymerase (RNA) III (DNA directed) polypeptide B
Synonyms: 2700078H01Rik, A330032P03Rik, RPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70428
VEGA: 10
Homologene: 6981
Afdn
Name: afadin, adherens junction formation factor
Synonyms: Afadin, I-afadin, AF6, S-afadin, Mllt4, 5033403D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Dhrs7b
Name: dehydrogenase/reductase (SDR family) member 7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216820
Homologene: 41044
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Alsin, 3222402C23Rik, 9430073A21Rik, Als2cr6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Cnot10
Name: CCR4-NOT transcription complex, subunit 10
Synonyms: 2600001P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78893
VEGA: 9
Homologene: 41040
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 2310003F20Rik, Garnl1, Tulip1, 4930400K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Ptprj
Name: protein tyrosine phosphatase receptor type J
Synonyms: DEP-1, RPTPJ, Scc-1, Scc1, CD148, Byp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Wtip
Name: WT1 interacting protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101543
Homologene: 64353
Ndufaf2
Name: NADH:ubiquinone oxidoreductase complex assembly factor 2
Synonyms: 1810058I14Rik, mimitin, Ndufa12l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75597
VEGA: 13
Homologene: 18372
Pcx
Name: pyruvate carboxylase
Synonyms: Pc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18563
VEGA: 19
HGNC: HGNC:8636
Homologene: 5422
Insig1
Name: insulin induced gene 1
Synonyms: 1810013C12Rik, Insig-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231070
HGNC: HGNC:6083
Homologene: 4047
Hhipl2
Name: hedgehog interacting protein-like 2
Synonyms: 4930507C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78772
Homologene: 11690
Adam17
Name: a disintegrin and metallopeptidase domain 17
Synonyms: CD156b, Tace
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11491
HGNC: HGNC:195
Homologene: 2395
Tube1
Name: tubulin, epsilon 1
Synonyms: 2310061K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71924
VEGA: 10
Homologene: 17762
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MTSG1, Atip1, B430305I03Rik, MD44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102103
Homologene: 100292
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: Zh2c2, 4930429M06, 4930429M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 252876
Homologene: 69238
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239102
Homologene: 52657
Ghr
Name: growth hormone receptor
Synonyms: GHBP, GHR/BP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14600
HGNC: HGNC:4263
Homologene: 134
Rnf168
Name: ring finger protein 168
Synonyms: 3110001H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70238
Homologene: 87044
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: Cmya3, 2310008C07Rik, A530024P18Rik, 2310003D02Rik, myomaxin, mXin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: SkM2, mH1, Nav1.5, Nav1.5c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20271
Homologene: 22738
Tmem132e
Name: transmembrane protein 132E
Synonyms: LOC270893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 270893
Homologene: 41524
Tcp11l2
Name: t-complex 11 (mouse) like 2
Synonyms: E430026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216198
Homologene: 17129
Tm7sf2
Name: transmembrane 7 superfamily member 2
Synonyms: ANG1, 3110041O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 73166
Homologene: 68305
Or2w4
Name: olfactory receptor family 2 subfamily W member 4
Synonyms: Olfr1362, Olfr1363-ps1, MOR256-8, GA_x6K02T2QHY8-11628399-11628868, GA_x6K02T2QHY8-11617756-11618682
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 258739
Homologene: 105885
Stard7
Name: START domain containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99138
Homologene: 32463
Vmn2r82
Name: vomeronasal 2, receptor 82
Synonyms: EG624845
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 624845
Homologene: 83483
Tecrl
Name: trans-2,3-enoyl-CoA reductase-like
Synonyms: D330017N19Rik, Srd5a2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243078
Homologene: 27549
AC132131.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: AK220484, mKIAA4095
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Ssc5d
Name: scavenger receptor cysteine rich family, 5 domains
Synonyms: A430110N23Rik, s5d-srcrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269855
Homologene: 77555
Cpb1
Name: carboxypeptidase B1 (tissue)
Synonyms: 2210008M23Rik, 1810063F02Rik, 0910001A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Abca14
Name: ATP-binding cassette, sub-family A (ABC1), member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67928
Homologene: 86128
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MEKK6, MAPKKK6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Grk4
Name: G protein-coupled receptor kinase 4
Synonyms: A830025H08Rik, Gprk2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14772
HGNC: HGNC:4543
Homologene: 23158
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: Dnahc7b, LOC227058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Ces1d
Name: carboxylesterase 1D
Synonyms: Ces3, TGH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Lipo4
Name: lipase, member O4
Synonyms: Gm6857
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 628236
Homologene: 103863
Tex14
Name: testis expressed gene 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83560
Homologene: 12838
Tm6sf2
Name: transmembrane 6 superfamily member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 107770
Homologene: 77694
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: LOC228796, Bpil3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228796
Homologene: 18375
Pcyt1a
Name: phosphate cytidylyltransferase 1, choline, alpha isoform
Synonyms: CTalpha, CTP:phosphocholine cytidylyltransferase alpha, Cttalpha, Ctpct, Cctalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13026
HGNC: HGNC:8754
Homologene: 3680
Cttnbp2
Name: cortactin binding protein 2
Synonyms: 4732477G22Rik, 3010022N24Rik, Cortbp2, 9130022E09Rik, ORF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 30785
Homologene: 14125
Or1i2
Name: olfactory receptor family 1 subfamily I member 1
Synonyms: MOR128-4, GA_x6K02T2QGN0-3196801-3197742, Olfr1357, MOR128-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 257883
HGNC: HGNC:8207
Homologene: 72920
Pdlim3
Name: PDZ and LIM domain 3
Synonyms: ALP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 53318
Homologene: 75063
Or5w11
Name: olfactory receptor family 5 subfamily W member 11
Synonyms: MOR177-4, GA_x6K02T2Q125-49133664-49134593, Olfr1131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258652
Homologene: 133019
Zfp763
Name: zinc finger protein 763
Synonyms: 1700065O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73451
Homologene: 66274
Plbd1
Name: phospholipase B domain containing 1
Synonyms: 1100001H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66857
Homologene: 11745
Gabrg2
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
Synonyms: gamma2, Gabrg-2, GABAA-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14406
HGNC: HGNC:4087
Homologene: 22443
Epx
Name: eosinophil peroxidase
Synonyms: EPO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13861
HGNC: HGNC:3423
Homologene: 20144
Gm454
Name: predicted gene 454
Synonyms: LOC243303
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243303
Pcdhb21
Name: protocadherin beta 21
Synonyms: PcdhbU, Pcdhb18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93892
Homologene: 134302
Ahr
Name: aryl-hydrocarbon receptor
Synonyms: Ah, In, bHLHe76, dioxin receptor, Ahre, Ahh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11622
HGNC: HGNC:348
Homologene: 1224
Gdf9
Name: growth differentiation factor 9
Synonyms: Gdf-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14566
HGNC: HGNC:4224
Homologene: 3851
Kcnf1
Name: potassium voltage-gated channel, subfamily F, member 1
Synonyms: LOC382571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 382571
HGNC: HGNC:6246
Homologene: 124236
Rcor2
Name: REST corepressor 2
Synonyms: CoREST, 1A13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 104383
Homologene: 14280
Gm9874
Name: predicted gene 9874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 46,290,646 bp
  • A to G, chromosome 1 at 59,180,147 bp
  • A to T, chromosome 1 at 97,786,150 bp
  • G to A, chromosome 1 at 105,721,428 bp
  • G to A, chromosome 1 at 118,504,959 bp
  • A to C, chromosome 1 at 133,624,687 bp
  • A to T, chromosome 1 at 181,917,197 bp
  • A to T, chromosome 1 at 183,423,524 bp
  • T to C, chromosome 2 at 59,322,554 bp
  • T to A, chromosome 2 at 67,510,295 bp
  • T to A, chromosome 2 at 87,628,977 bp
  • T to C, chromosome 2 at 90,463,320 bp
  • T to A, chromosome 2 at 127,295,486 bp
  • T to C, chromosome 2 at 153,906,861 bp
  • G to T, chromosome 3 at 20,263,782 bp
  • C to T, chromosome 4 at 41,199,872 bp
  • T to G, chromosome 4 at 133,252,473 bp
  • C to T, chromosome 4 at 138,126,563 bp
  • C to T, chromosome 5 at 28,071,708 bp
  • T to C, chromosome 5 at 34,731,538 bp
  • T to G, chromosome 5 at 44,473,472 bp
  • T to C, chromosome 5 at 83,280,508 bp
  • A to G, chromosome 5 at 138,203,941 bp
  • T to A, chromosome 6 at 18,435,433 bp
  • T to C, chromosome 6 at 136,612,306 bp
  • C to A, chromosome 7 at 4,944,043 bp
  • T to C, chromosome 7 at 34,116,595 bp
  • C to T, chromosome 7 at 120,251,291 bp
  • C to T, chromosome 8 at 41,015,409 bp
  • A to T, chromosome 8 at 45,896,859 bp
  • T to C, chromosome 8 at 70,077,994 bp
  • C to T, chromosome 8 at 93,186,118 bp
  • A to G, chromosome 8 at 123,949,035 bp
  • A to T, chromosome 9 at 114,629,095 bp
  • C to A, chromosome 9 at 119,486,092 bp
  • A to G, chromosome 10 at 39,144,766 bp
  • G to T, chromosome 10 at 78,612,140 bp
  • A to G, chromosome 10 at 79,379,419 bp
  • C to T, chromosome 10 at 84,613,487 bp
  • C to A, chromosome 10 at 84,652,783 bp
  • A to T, chromosome 10 at 90,042,548 bp
  • T to A, chromosome 11 at 41,976,663 bp
  • A to T, chromosome 11 at 53,437,511 bp
  • T to G, chromosome 11 at 60,851,891 bp
  • A to T, chromosome 11 at 62,525,176 bp
  • T to C, chromosome 11 at 69,036,150 bp
  • C to T, chromosome 11 at 70,005,140 bp
  • A to G, chromosome 11 at 82,437,370 bp
  • A to T, chromosome 11 at 87,554,928 bp
  • T to C, chromosome 11 at 87,868,712 bp
  • C to G, chromosome 12 at 17,175,732 bp
  • T to A, chromosome 12 at 21,334,138 bp
  • T to C, chromosome 12 at 35,515,017 bp
  • T to G, chromosome 12 at 55,741,536 bp
  • A to C, chromosome 13 at 21,611,764 bp
  • C to T, chromosome 13 at 108,091,573 bp
  • A to T, chromosome 14 at 50,824,563 bp
  • A to T, chromosome 14 at 55,062,985 bp
  • T to C, chromosome 15 at 3,320,574 bp
  • T to A, chromosome 16 at 32,289,151 bp
  • T to C, chromosome 16 at 32,467,119 bp
  • C to T, chromosome 17 at 13,810,501 bp
  • T to A, chromosome 17 at 30,485,762 bp
  • G to T, chromosome 17 at 31,333,558 bp
  • T to C, chromosome 17 at 33,019,907 bp
  • A to G, chromosome 18 at 10,529,703 bp
  • A to T, chromosome 18 at 37,515,479 bp
  • A to T, chromosome 19 at 4,603,159 bp
  • A to G, chromosome 19 at 6,063,019 bp
  • G to A, chromosome 19 at 7,271,105 bp
  • T to G, chromosome 19 at 33,512,673 bp
  • A to T, chromosome 19 at 37,387,200 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1607 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039644-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.