Strain Name:
C57BL/6J-MtgxR1620Btlr/Mmmh
Stock Number:
039657-MU
Citation ID:
RRID:MMRRC_039657-MU
Other Names:
R1620 (G1), C57BL/6J-MtgxR1620Btlr
Major Collection:

Gene Information

Epha4
Name: Eph receptor A4
Synonyms: 2900005C20Rik, rb, Sek1, Hek8, Cek8, Sek, Tyro1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13838
HGNC: HGNC:3388
Homologene: 20933
Pcdh9
Name: protocadherin 9
Synonyms: A730003J17Rik, C530050I23Rik, C630029H24Rik, 1500001L12Rik, LOC382930
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: 5730557L09Rik, roquin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381305
Homologene: 19036
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: NLRR-1, 2810047E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16979
Homologene: 32036
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20269
Homologene: 56005
Dlgap4
Name: DLG associated protein 4
Synonyms: WBP16, SAP90/PSD-95-associated protein 4, PSD-95/SAP90 binding protein 4, Sapap4, DAP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228836
Homologene: 8935
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: Pdzgef2, RA-GEF-2, C030018K18Rik, PDZ-GEF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192786
Homologene: 22968
Nomo1
Name: nodal modulator 1
Synonyms: Nomo, D7Ertd156e, PM5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 211548
Homologene: 13810
Pparg
Name: peroxisome proliferator activated receptor gamma
Synonyms: Nr1c3, PPARgamma2, PPARgamma, Ppar-gamma2, PPAR-gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19016
HGNC: HGNC:9236
Homologene: 7899
Tank
Name: TRAF family member-associated Nf-kappa B activator
Synonyms: I-TRAF, E430026L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21353
Homologene: 3081
Txnrd1
Name: thioredoxin reductase 1
Synonyms: TrxR1, TR, TR alpha, TR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 50493
VEGA: 10
Homologene: 55733
Gga1
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 1
Synonyms: 4930406E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106039
VEGA: 15
Homologene: 39250
Gigyf2
Name: GRB10 interacting GYF protein 2
Synonyms: A830080H02Rik, Tnrc15, 2610016F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227331
Homologene: 41048
Mrpl2
Name: mitochondrial ribosomal protein L2
Synonyms: Rpml14, CGI-22, MRP-L14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 27398
Homologene: 69198
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73732
Homologene: 141193
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Wdr6
Name: WD repeat domain 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83669
Homologene: 117682
Clec4a2
Name: C-type lectin domain family 4, member a2
Synonyms: dendritic cell immunoreceptor, Dcir1, Clecsf6, DCIR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26888
Homologene: 49291
Chst9
Name: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Synonyms: GalNAc4ST-2, 5430438D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 71367
Homologene: 12861
Mecom
Name: MDS1 and EVI1 complex locus
Synonyms: Prdm3, Evi-1, Evi1, Mds1, D630039M04Rik, ZNFPR1B1, Jbo, MDS1-EVI1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14013
HGNC: HGNC:3498
Homologene: 21086
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Itga9
Name: integrin alpha 9
Synonyms: D9Ertd428e, 6720458D17Rik, 2610002H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 104099
HGNC: HGNC:6145
Homologene: 1664
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: Cmya3, mXin beta, myomaxin, 2310003D02Rik, 2310008C07Rik, A530024P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227334
Homologene: 32400
Atp2c2
Name: ATPase, Ca++ transporting, type 2C, member 2
Synonyms: 1810010G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69047
Homologene: 73463
Ulk4
Name: unc-51-like kinase 4
Synonyms: 4932415A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 209012
Homologene: 41205
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320118
Homologene: 27057
Myh3
Name: myosin, heavy polypeptide 3, skeletal muscle, embryonic
Synonyms: Myhs-e, Myhse, MyHC-emb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17883
HGNC: HGNC:7573
Homologene: 20553
Chl1
Name: cell adhesion molecule L1-like
Synonyms: LICAM2, A530023M13Rik, CALL, close homolog of L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: Rpel1, 9630030F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218194
Homologene: 33597
Vmn1r194
Name: vomeronasal 1 receptor 194
Synonyms: Gm11294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 626299
Homologene: 110880
C130026I21Rik
Name: RIKEN cDNA C130026I21 gene
Synonyms: OTTMUSG00000029174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 620078
Homologene: 131208
Tbc1d9
Name: TBC1 domain family, member 9
Synonyms: C76116, 4933431N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71310
Homologene: 57079
Capn2
Name: calpain 2
Synonyms: m-calpain, Capa-2, Capa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12334
HGNC: HGNC:1479
Homologene: 1326
Myocd
Name: myocardin
Synonyms: Srfcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214384
Homologene: 17043
Vmn1r170
Name: vomeronasal 1 receptor 170
Synonyms: Gm5999
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546944
Homologene: 128341
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233328
Homologene: 23464
Gm10845
Name: predicted gene 10845
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100038734
VEGA: 14
Capn13
Name: calpain 13
Synonyms: LOC381122
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381122
VEGA: 17
Homologene: 27026
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213402
Homologene: 41848
Spata17
Name: spermatogenesis associated 17
Synonyms: 1700065F16Rik, 4930504I07Rik, 4930513F16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74717
Homologene: 12551
Myot
Name: myotilin
Synonyms: Ttid, 5530402I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 58916
Homologene: 4942
Fscn2
Name: fascin actin-bundling protein 2
Synonyms: C630046B20Rik, ahl8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 238021
HGNC: HGNC:3960
Homologene: 22722
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Nalp5, Mater, Op1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 23968
Homologene: 65105
Atp8a2
Name: ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
Synonyms: agil, Ib, wl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50769
Homologene: 4443
Cyp2u1
Name: cytochrome P450, family 2, subfamily u, polypeptide 1
Synonyms: 8430436A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71519
Homologene: 77704
Tfpi2
Name: tissue factor pathway inhibitor 2
Synonyms: PP5/TFPI-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21789
Homologene: 38194
Maip1
Name: matrix AAA peptidase interacting protein 1
Synonyms: 9430016H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68115
Homologene: 11565
Cfc1
Name: cripto, FRL-1, cryptic family 1
Synonyms: b2b970Clo, cryptic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12627
Homologene: 50007
Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Synonyms: 90kDa, 1110069D02Rik, MSK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56613
VEGA: 19
Homologene: 69288
Ston1
Name: stonin 1
Synonyms: 4921524J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77057
Homologene: 122152
Bfar
Name: bifunctional apoptosis regulator
Synonyms: 3010001A07Rik, RNF47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67118
Homologene: 9563
Olfr1312
Name: olfactory receptor 1312
Synonyms: MOR245-20, GA_x6K02T2Q125-73090482-73089529
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258359
Homologene: 128122
Npas2
Name: neuronal PAS domain protein 2
Synonyms: MOP4, bHLHe9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18143
HGNC: HGNC:7895
Homologene: 1887
Obox2
Name: oocyte specific homeobox 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246792
Homologene: 44937
Gm11559
Name: predicted gene 11559
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100415785
Homologene: 136354
Sf3b6
Name: splicing factor 3B, subunit 6
Synonyms: Sf3b14, 0610009D07Rik, 6030419K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66055
VEGA: 12
Homologene: 9360
Ac079181.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Gm10037
Name: predicted gene 10037
Synonyms: EG328280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 102637366
VEGA: 13
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 34,536,473 bp
  • T to C, chromosome 1 at 39,333,912 bp
  • T to C, chromosome 1 at 57,409,985 bp
  • T to A, chromosome 1 at 77,374,926 bp
  • A to G, chromosome 1 at 85,254,186 bp
  • A to G, chromosome 1 at 87,449,128 bp
  • A to T, chromosome 1 at 87,994,225 bp
  • T to C, chromosome 1 at 160,954,973 bp
  • A to T, chromosome 1 at 182,517,137 bp
  • T to C, chromosome 1 at 187,183,215 bp
  • A to G, chromosome 2 at 61,650,098 bp
  • C to T, chromosome 2 at 65,529,375 bp
  • T to A, chromosome 2 at 67,510,835 bp
  • G to T, chromosome 2 at 112,042,246 bp
  • T to A, chromosome 2 at 156,749,136 bp
  • A to T, chromosome 3 at 29,987,088 bp
  • A to G, chromosome 3 at 131,302,701 bp
  • A to T, chromosome 5 at 21,519,421 bp
  • T to C, chromosome 5 at 124,832,643 bp
  • T to A, chromosome 6 at 3,965,507 bp
  • T to C, chromosome 6 at 103,690,242 bp
  • G to A, chromosome 6 at 107,568,366 bp
  • A to T, chromosome 6 at 115,473,281 bp
  • A to T, chromosome 6 at 123,125,100 bp
  • A to G, chromosome 7 at 15,397,041 bp
  • A to G, chromosome 7 at 23,418,639 bp
  • A to G, chromosome 7 at 23,606,329 bp
  • A to G, chromosome 7 at 46,078,151 bp
  • G to A, chromosome 7 at 46,249,124 bp
  • G to T, chromosome 7 at 66,381,538 bp
  • T to A, chromosome 8 at 83,249,595 bp
  • T to C, chromosome 8 at 119,749,126 bp
  • A to G, chromosome 9 at 18,510,477 bp
  • A to T, chromosome 9 at 108,574,655 bp
  • A to G, chromosome 9 at 118,843,502 bp
  • T to G, chromosome 9 at 121,204,805 bp
  • G to A, chromosome 10 at 41,922,296 bp
  • C to T, chromosome 10 at 82,884,015 bp
  • A to T, chromosome 11 at 54,626,594 bp
  • A to G, chromosome 11 at 65,196,394 bp
  • C to T, chromosome 11 at 67,088,736 bp
  • T to A, chromosome 11 at 99,865,056 bp
  • A to T, chromosome 11 at 120,366,685 bp
  • T to C, chromosome 12 at 4,826,808 bp
  • T to C, chromosome 12 at 115,067,875 bp
  • A to G, chromosome 13 at 22,244,963 bp
  • G to T, chromosome 13 at 43,094,897 bp
  • T to C, chromosome 13 at 67,842,990 bp
  • T to A, chromosome 14 at 59,791,183 bp
  • C to A, chromosome 14 at 79,863,229 bp
  • G to A, chromosome 14 at 93,888,305 bp
  • G to A, chromosome 15 at 78,888,470 bp
  • G to T, chromosome 16 at 13,688,846 bp
  • G to A, chromosome 17 at 46,647,499 bp
  • A to G, chromosome 17 at 67,767,033 bp
  • A to T, chromosome 17 at 73,316,308 bp
  • A to G, chromosome 17 at 88,635,816 bp
  • A to G, chromosome 18 at 15,498,106 bp
  • A to T, chromosome 18 at 44,337,058 bp
  • T to C, chromosome 19 at 6,838,149 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1620 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039657-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.