Strain Name:
C57BL/6J-MtgxR1658Btlr/Mmmh
Stock Number:
039694-MU
Citation ID:
RRID:MMRRC_039694-MU
Other Names:
R1658 (G1), C57BL/6J-MtgxR1658Btlr
Major Collection:

Gene Information

Elp2
Name: elongator acetyltransferase complex subunit 2
Synonyms: StIP1, Stat3-interacting protein, Statip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 58523
VEGA: 18
Homologene: 6019
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: D12Ertd7e, Dicer1, 1110006F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Rgs7
Name: regulator of G protein signaling 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 24012
Homologene: 2193
Tjp2
Name: tight junction protein 2
Synonyms: ZO-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21873
VEGA: 19
Homologene: 3541
Mga
Name: MAX gene associated
Synonyms: D030062C11Rik, C130042M01Rik, Mga, Mad5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Cemip2
Name: cell migration inducing hyaluronidase 2
Synonyms: Tmem2, 3110012M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 83921
VEGA: 19
Homologene: 75008
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108912
Homologene: 18444
Ticrr
Name: TOPBP1-interacting checkpoint and replication regulator
Synonyms: 5730590G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77011
Homologene: 67120
Rbm5
Name: RNA binding motif protein 5
Synonyms: D030069N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83486
HGNC: HGNC:9902
Homologene: 21177
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: C030005G16Rik, Walp3, Tip5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Max
Name: Max protein
Synonyms: bHLHd5, bHLHd4, bHLHd6, bHLHd7, bHLHd8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17187
VEGA: 12
HGNC: HGNC:6913
Homologene: 1786
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: Wdr11, Ndrp, 4632404O06Rik, 2810004D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83946
Homologene: 41209
Klhl24
Name: kelch-like 24
Synonyms: 6530402O20Rik, 1110046J11Rik, 4930429H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 75785
VEGA: 16
Homologene: 32352
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: dgkd-2, DGKdelta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Gabbr1
Name: gamma-aminobutyric acid (GABA) B receptor, 1
Synonyms: GABAB1, GABAbR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54393
HGNC: HGNC:4070
Homologene: 1132
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: QBRICK, eyem02Jus, eyes2, crf11, heb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Amph
Name: amphiphysin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218038
HGNC: HGNC:471
Homologene: 121585
Rpl24
Name: ribosomal protein L24
Synonyms: 0610008L05Rik, Bst
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68193
Homologene: 763
Heatr6
Name: HEAT repeat containing 6
Synonyms: 2700008B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217026
Homologene: 11116
Ubxn7
Name: UBX domain protein 7
Synonyms: Ubxd7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224111
VEGA: 16
Homologene: 45585
Tbc1d2
Name: TBC1 domain family, member 2
Synonyms: PARIS-1, LOC381605, PARIS1, A630005A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381605
Homologene: 10190
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Gm7348, Corl2, Fussel18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Lcp2
Name: lymphocyte cytosolic protein 2
Synonyms: twm, SLP76, SLP-76, m1Khoe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16822
HGNC: HGNC:6529
Homologene: 4065
Trpv5
Name: transient receptor potential cation channel, subfamily V, member 5
Synonyms: ECaC1, CaT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194352
HGNC: HGNC:3145
Homologene: 10520
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hy-3, hy3, 4930545D19Rik, hyrh, 1700034M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244653
Homologene: 52118
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: B430006D22Rik, D230004J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194388
Homologene: 35360
AC159748.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Intu
Name: inturned planar cell polarity protein
Synonyms: 9430087H23Rik, 9230116I04Rik, Pdzd6, Pdzk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 380614
Homologene: 41059
G6pc2
Name: glucose-6-phosphatase, catalytic, 2
Synonyms: G6pc-rs, islet specific glucose-6-phosphatase, IGRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14378
Homologene: 41423
Ints11
Name: integrator complex subunit 11
Synonyms: Cpsf3l, 2410006F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71957
Homologene: 9894
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Rin2
Name: Ras and Rab interactor 2
Synonyms: RASSF4, 4632403N06Rik, 2010003K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74030
Homologene: 32430
Stard9
Name: START domain containing 9
Synonyms: E230025N21Rik, Kif16a, 4831403C07Rik, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Lipm
Name: lipase, family member M
Synonyms: Lipl3, 4632427C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78753
VEGA: 19
Homologene: 28267
Apbb1
Name: amyloid beta (A4) precursor protein-binding, family B, member 1
Synonyms: Fe65, Rir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11785
HGNC: HGNC:581
Homologene: 898
Vmn2r66
Name: vomeronasal 2, receptor 66
Synonyms: F830104D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233437
Homologene: 115466
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319807
Homologene: 14974
Ninl
Name: ninein-like
Synonyms: 4930519N13Rik, LOC381387, LOC381388
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78177
Homologene: 57024
Tubb1
Name: tubulin, beta 1 class VI
Synonyms: 2810484G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545486
Homologene: 69474
Plxnb1
Name: plexin B1
Synonyms: 2900002G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235611
HGNC: HGNC:9103
Homologene: 130508
Olfr144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Fbxo11
Name: F-box protein 11
Synonyms: GENA 104, Jf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225055
Homologene: 11843
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
Naaa
Name: N-acylethanolamine acid amidase
Synonyms: Asahl, 3830414F09Rik, 2210023K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67111
HGNC: HGNC:736
Homologene: 8686
Tmem38b
Name: transmembrane protein 38B
Synonyms: 1600017F22Rik, D4Ertd89e, TRIC-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 52076
Homologene: 10010
Trabd
Name: TraB domain containing
Synonyms: 5730502D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67976
Homologene: 36427
Tcerg1l
Name: transcription elongation regulator 1-like
Synonyms: 5730476P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70571
Homologene: 52165
Gbp9
Name: guanylate-binding protein 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 236573
Homologene: 128731
Abcd2
Name: ATP-binding cassette, sub-family D (ALD), member 2
Synonyms: ABC39, ALDR, ALDL1, adrenoleukodystrophy related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 26874
VEGA: 15
HGNC: HGNC:66
Homologene: 55873
Cd84
Name: CD84 antigen
Synonyms: A130013D22Rik, SLAMF5, CDw84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Olfr421-ps1
Name: olfactory receptor 421, pseudogene 1
Synonyms: GA_x6K02T2P20D-21002372-21001425, Olfr422-ps1, Olfr421, MOR105-3, GA_x6K02T2P20D-21006310-21006124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258715
Msantd1
Name: Myb/SANT-like DNA-binding domain containing 1
Synonyms: A930005I04Rik, LOC231132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 403174
Homologene: 45807
Mylk4
Name: myosin light chain kinase family, member 4
Synonyms: EG238564
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238564
Homologene: 66243
Chfr
Name: checkpoint with forkhead and ring finger domains
Synonyms: RNF116, 5730484M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231600
Homologene: 10078
Ugp2
Name: UDP-glucose pyrophosphorylase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216558
Homologene: 121676
Scrn1
Name: secernin 1
Synonyms: 6330535A03Rik, SES1, 2810019K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69938
Homologene: 8853
Rps18
Name: ribosomal protein S18
Synonyms: H2-Ke3, H-2Ke3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20084
Homologene: 88764
Gstp1
Name: glutathione S-transferase, pi 1
Synonyms: Gst p-1, GstpiB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14870
HGNC: HGNC:4638
Homologene: 660
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 87,926,268 bp
  • T to C, chromosome 1 at 136,171,285 bp
  • A to G, chromosome 1 at 171,872,750 bp
  • G to A, chromosome 1 at 174,152,223 bp
  • T to C, chromosome 1 at 175,079,554 bp
  • A to T, chromosome 2 at 69,227,069 bp
  • A to G, chromosome 2 at 112,640,301 bp
  • C to T, chromosome 2 at 112,861,780 bp
  • A to T, chromosome 2 at 119,941,689 bp
  • T to C, chromosome 2 at 120,701,542 bp
  • A to T, chromosome 2 at 145,876,456 bp
  • A to G, chromosome 2 at 150,964,159 bp
  • A to C, chromosome 2 at 174,456,623 bp
  • A to G, chromosome 3 at 40,692,781 bp
  • G to A, chromosome 4 at 46,614,207 bp
  • A to G, chromosome 4 at 53,840,713 bp
  • C to T, chromosome 4 at 83,001,808 bp
  • A to G, chromosome 4 at 155,887,728 bp
  • C to A, chromosome 5 at 34,921,561 bp
  • T to A, chromosome 5 at 34,921,562 bp
  • A to G, chromosome 5 at 63,807,246 bp
  • T to C, chromosome 5 at 92,272,441 bp
  • T to A, chromosome 5 at 105,094,468 bp
  • T to C, chromosome 5 at 110,153,169 bp
  • T to G, chromosome 5 at 129,178,100 bp
  • T to C, chromosome 6 at 18,235,449 bp
  • T to A, chromosome 6 at 41,614,245 bp
  • C to A, chromosome 6 at 41,674,282 bp
  • T to A, chromosome 6 at 54,520,806 bp
  • A to T, chromosome 6 at 83,369,057 bp
  • A to T, chromosome 7 at 79,695,549 bp
  • G to T, chromosome 7 at 85,007,747 bp
  • G to A, chromosome 7 at 105,574,084 bp
  • A to G, chromosome 7 at 138,394,180 bp
  • A to G, chromosome 8 at 16,081,725 bp
  • T to A, chromosome 8 at 110,494,279 bp
  • C to T, chromosome 9 at 39,237,959 bp
  • A to G, chromosome 9 at 82,871,498 bp
  • G to A, chromosome 9 at 107,750,002 bp
  • T to A, chromosome 9 at 109,102,871 bp
  • T to G, chromosome 10 at 5,367,616 bp
  • T to A, chromosome 10 at 128,124,383 bp
  • G to A, chromosome 11 at 21,333,774 bp
  • A to G, chromosome 11 at 34,075,309 bp
  • A to G, chromosome 11 at 83,758,367 bp
  • A to T, chromosome 12 at 76,938,581 bp
  • A to G, chromosome 12 at 104,700,414 bp
  • T to G, chromosome 13 at 19,103,014 bp
  • T to C, chromosome 13 at 32,712,789 bp
  • A to G, chromosome 14 at 67,677,699 bp
  • T to A, chromosome 15 at 89,085,866 bp
  • C to T, chromosome 15 at 91,159,090 bp
  • T to A, chromosome 16 at 20,107,092 bp
  • A to G, chromosome 16 at 32,381,236 bp
  • A to T, chromosome 16 at 55,974,225 bp
  • A to T, chromosome 17 at 33,952,418 bp
  • A to G, chromosome 17 at 37,047,507 bp
  • A to T, chromosome 17 at 88,012,658 bp
  • C to T, chromosome 18 at 24,617,413 bp
  • A to T, chromosome 18 at 76,894,089 bp
  • A to T, chromosome 19 at 4,037,375 bp
  • T to C, chromosome 19 at 21,801,879 bp
  • T to C, chromosome 19 at 24,112,947 bp
  • C to T, chromosome 19 at 34,116,447 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1658 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039694-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.