Strain Name:
C57BL/6J-MtgxR1670Btlr/Mmmh
Stock Number:
039706-MU
Citation ID:
RRID:MMRRC_039706-MU
Other Names:
R1670 (G1), C57BL/6J-MtgxR1670Btlr
Major Collection:

Strain Information

Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20349
Homologene: 8247
Rprd2
Name: regulation of nuclear pre-mRNA domain containing 2
Synonyms: 2810036A19Rik, 4930535B03Rik, 6720469I21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75137
Homologene: 19997
Nup188
Name: nucleoporin 188
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227699
Homologene: 45683
Rnf38
Name: ring finger protein 38
Synonyms: 2610202O07Rik, 1700065B19Rik, Oip1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73469
Homologene: 32550
Lactb2
Name: lactamase, beta 2
Synonyms: E430032H21Rik, Cgi-83
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 212442
Homologene: 9349
Slc37a1
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 1
Synonyms: G3PP
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224674
VEGA: 17
Homologene: 70486
Gdnf
Name: glial cell line derived neurotrophic factor
Synonyms: glial cell line-derived neurotrophic factor
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14573
VEGA: 15
HGNC: HGNC:4232
Homologene: 433
Rngtt
Name: RNA guanylyltransferase and 5'-phosphatase
Synonyms: mouse capping enzyme
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 24018
Homologene: 37851
Gpr55
Name: G protein-coupled receptor 55
Synonyms: CTFL, LOC227326
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227326
HGNC: HGNC:4511
Homologene: 36184
Ndnf
Name: neuron-derived neurotrophic factor
Synonyms: epidermacan, A930038C07Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68169
Homologene: 11593
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229584
Homologene: 9022
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Banp
Name: BTG3 associated nuclear protein
Synonyms: SMAR1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 53325
Homologene: 9635
Coro7
Name: coronin 7
Synonyms: 0610011B16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78885
Homologene: 11573
Gdf10
Name: growth differentiation factor 10
Synonyms: Bmp3b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14560
VEGA: 14
HGNC: HGNC:4215
Homologene: 3640
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: TAF3B1, Tfnr, TFC5, TFIIIB90, TFIIIB150, B130055N23Rik, G630013P12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 544971
Homologene: 34582
Angel2
Name: angel homolog 2
Synonyms: D1Ertd654e, 2610307I21Rik, D1Ertd396e, 5730410O10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52477
Homologene: 16932
Ift122
Name: intraflagellar transport 122
Synonyms: C86139, sopb, Wdr10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 81896
Homologene: 12819
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: H-FABP, Fabph1, Mdgi, Fabph-4, Fabph-1, Fabph4, Fabp3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Camta1
Name: calmodulin binding transcription activator 1
Synonyms: 2310058O09Rik, 1810059M14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100072
Homologene: 18942
Fgfr2
Name: fibroblast growth factor receptor 2
Synonyms: KGFRTr, Bek, svs, Fgfr2b, Fgfr7, Fgfr-7, Fgfr-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14183
HGNC: HGNC:3689
Homologene: 22566
Scamp4
Name: secretory carrier membrane protein 4
Synonyms: Sc4, 2410022D05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56214
VEGA: 10
Homologene: 10476
Steap2
Name: six transmembrane epithelial antigen of prostate 2
Synonyms: 4921538B17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74051
Homologene: 17682
Calr
Name: calreticulin
Synonyms: CRT, Calregulin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12317
HGNC: HGNC:1455
Homologene: 37911
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, b2b414Clo, Dnchc2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, m152Asp, m407Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104401
Homologene: 17000
Pnisr
Name: PNN interacting serine/arginine-rich
Synonyms: Sfrs18, 5730406M06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66625
Homologene: 32802
Tmem68
Name: transmembrane protein 68
Synonyms: 2010300G19Rik, Diesl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72098
Homologene: 12440
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: we, TG E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21818
Homologene: 20690
Adam15
Name: ADAM metallopeptidase domain 15
Synonyms: metargidin, MDC15
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11490
HGNC: HGNC:193
Homologene: 2829
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: Ttc40, 9330101J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Med12l
Name: mediator complex subunit 12-like
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329650
Homologene: 43143
Dennd6b
Name: DENN domain containing 6B
Synonyms: 1700027J05Rik, Fam116b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69440
VEGA: 15
Homologene: 57065
Ttpal
Name: tocopherol (alpha) transfer protein-like
Synonyms: 3110080A02Rik, 5830472M02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76080
Homologene: 41562
Pld1
Name: phospholipase D1
Synonyms: Pld1b, Pld1a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18805
HGNC: HGNC:9067
Homologene: 116234
Gucy1b1
Name: guanylate cyclase 1, soluble, beta 1
Synonyms: beta 1 sGC, Gucy1b3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54195
HGNC: HGNC:4687
Homologene: 664
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228602
Homologene: 12623
Xkr9
Name: X-linked Kx blood group related 9
Synonyms: LOC381246
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381246
Homologene: 20056
Cfap69
Name: cilia and flagella associated protein 69
Synonyms: A330021E22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207686
Homologene: 11718
F12
Name: coagulation factor XII (Hageman factor)
Synonyms: FXII
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 58992
HGNC: HGNC:3530
Homologene: 425
Parp10
Name: poly (ADP-ribose) polymerase family, member 10
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 671535
Homologene: 53133
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: Sur2, SUR2A, SUR2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Or5ac23
Name: olfactory receptor family 5 subfamily AC member 23
Synonyms: Olfr205, MOR182-11P, GA_x54KRFPKG5P-55543875-55542958
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257881
Homologene: 79469
Stxbp5l
Name: syntaxin binding protein 5-like
Synonyms: T2dm1, insulin level locus 1, A830015P08Rik, LLGL4, t2md1, tomosyn-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207227
Homologene: 18173
Cspg4
Name: chondroitin sulfate proteoglycan 4
Synonyms: 4732461B14Rik, NG2, AN2, Cspg4a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 121021
VEGA: 9
HGNC: HGNC:2466
Homologene: 20445
Ptprn2
Name: protein tyrosine phosphatase receptor type N polypeptide 2
Synonyms: IA-2 beta, 4930425H11Rik, PTP-NP, IA-2beta, phogrin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Hycc1
Name: hyccin PI4KA lipid kinase complex subunit 1
Synonyms: hyccin, Fam126a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 84652
Homologene: 57175
Ttc41
Name: tetratricopeptide repeat domain 41
Synonyms: BC030307, Gnn
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103220
VEGA: 10
Homologene: 52968
Elfn2
Name: leucine rich repeat and fibronectin type III, extracellular 2
Synonyms: Lrrc62
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 207393
VEGA: 15
Homologene: 18835
Dhx30
Name: DExH-box helicase 30
Synonyms: 2810477H02Rik, C130058C04Rik, helG, DEAH (Asp-Glu-Ala-His) box polypeptide 30, Ddx30
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72831
Homologene: 15779
Mansc4
Name: MANSC domain containing 4
Synonyms: Gm5887
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 545893
Homologene: 86837
Shpk
Name: sedoheptulokinase
Synonyms: Carkl, 4930431K22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74637
HGNC: HGNC:1492
Homologene: 8319
Rln1
Name: relaxin 1
Synonyms: rlx
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19773
Homologene: 55524
Sema5a
Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Synonyms: semF, 9130201M22Rik, Semaf, M-Sema D
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20356
VEGA: 15
Homologene: 2949
Or52i2
Name: olfactory receptor family 52 subfamily J member 2
Synonyms: GA_x6K02T2PBJ9-5386601-5387575, Olfr556, MOR41-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258749
Homologene: 17380
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665376
Homologene: 115024
Hnf4a
Name: hepatic nuclear factor 4, alpha
Synonyms: HNF-4, Tcf4, Nuclear receptor 2A1, Tcf14, HNF4 alpha, Hnf4, Nr2a1, MODY1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15378
HGNC: HGNC:5024
Homologene: 395
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: 1110059C24Rik, ALP56, BAE2, CEAP1, ARP1, ASP21, CDA13
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Muc17
Name: mucin 17, cell surface associated
Synonyms: Muc3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666339
Homologene: 141159
Nek4
Name: NIMA (never in mitosis gene a)-related expressed kinase 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 23955
VEGA: 14
Homologene: 2376
Or5m9b
Name: olfactory receptor family 5 subfamily M member 9B
Synonyms: MOR262-13, MOR245-25, GA_x6K02T2Q125-47549689-47550621, Olfr1036
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258245
Lrfn2
Name: leucine rich repeat and fibronectin type III domain containing 2
Synonyms: 5730420O05Rik, SALM1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70530
Homologene: 19182
Slc22a20
Name: solute carrier family 22 (organic anion transporter), member 20
Synonyms: mOAT6, LOC381203
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381203
Homologene: 87203
Redic1
Name: regulator of DNA class I crossover intermediates 1
Synonyms: Gm5807, CN725425
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545126
Spon1
Name: spondin 1, (f-spondin) extracellular matrix protein
Synonyms: D330035F22Rik, FSP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233744
Homologene: 4453
Or10j2
Name: olfactory receptor family 10 subfamily J member 2
Synonyms: GA_x6K02T2R7CC-581296-580364, Olfr418-ps1, GA_x6K02T2P20D-20826777-20827719, Olfr418, MOR267-12P, MOR267-8, Olfr1403
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258645
HGNC: HGNC:8175
Homologene: 8218
Nkx2-6
Name: NK2 homeobox 6
Synonyms: Tix, Nkx-2.6, Nkx2.6, tinman
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18092
Homologene: 22604
Cib2
Name: calcium and integrin binding family member 2
Synonyms: 2810434I23Rik, calcium binding protein Kip2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56506
Homologene: 4653
Or4f14b
Name: olfactory receptor family 4 subfamily F member 14B
Synonyms: MOR245-19P, GA_x6K02T2Q125-72988111-72987173, Olfr1307
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257956
Homologene: 128383
Or5ac24
Name: olfactory receptor family 5 subfamily AC member 24
Synonyms: GA_x54KRFPKG5P-55560552-55559632, Olfr206, MOR182-4
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258993
Homologene: 74262
Car11
Name: carbonic anhydrase 11
Synonyms: CA-RP XI
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12348
HGNC: HGNC:1370
Homologene: 36061
Hsfy2
Name: heat shock transcription factor, Y-linked 2
Synonyms: 4933413G11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71066
Homologene: 134090
Gm9857
Name: predicted gene 9857
Type: Gene
Species: Mouse
Chromosome: 3
Il27
Name: interleukin 27
Synonyms: IL-27p28, IL-27, p28, Il30
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246779
Homologene: 17087
Or2t48
Name: olfactory receptor family 2 subfamily T member 48
Synonyms: GA_x6K02T2NKPP-895420-896349, Olfr330, MOR275-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258879
Homologene: 133015
Ebi3
Name: Epstein-Barr virus induced gene 3
Synonyms: IL-27, EBI-3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50498
VEGA: 17
HGNC: HGNC:3129
Homologene: 4207
Gpatch11
Name: G patch domain containing 11
Synonyms: Ccdc75, 2310002B06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53951
VEGA: 17
Homologene: 44687
Mrpl16
Name: mitochondrial ribosomal protein L16
Synonyms: 2310039D06Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94063
VEGA: 19
Homologene: 9872
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 13,660,417 bp
  • G to A, chromosome 1 at 13,700,943 bp
  • A to G, chromosome 1 at 56,636,389 bp
  • A to G, chromosome 1 at 85,941,415 bp
  • T to A, chromosome 1 at 173,270,900 bp
  • T to A, chromosome 1 at 190,942,163 bp
  • T to C, chromosome 2 at 30,340,655 bp
  • T to A, chromosome 2 at 86,075,250 bp
  • C to T, chromosome 2 at 111,944,919 bp
  • G to T, chromosome 2 at 130,041,768 bp
  • G to A, chromosome 2 at 130,712,379 bp
  • T to C, chromosome 2 at 163,562,576 bp
  • T to C, chromosome 2 at 163,615,366 bp
  • A to T, chromosome 3 at 28,049,240 bp
  • AACAGCA to AACAGCAACAGCA, chromosome 3 at 59,275,958 bp
  • A to G, chromosome 3 at 82,045,460 bp
  • T to C, chromosome 3 at 89,348,510 bp
  • C to T, chromosome 3 at 94,878,849 bp
  • G to T, chromosome 3 at 95,764,803 bp
  • A to T, chromosome 3 at 108,940,162 bp
  • A to C, chromosome 4 at 3,560,627 bp
  • A to G, chromosome 4 at 21,865,893 bp
  • A to G, chromosome 4 at 33,368,660 bp
  • A to G, chromosome 4 at 44,138,681 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • T to C, chromosome 4 at 151,079,771 bp
  • A to T, chromosome 5 at 5,586,409 bp
  • A to G, chromosome 5 at 5,677,393 bp
  • C to T, chromosome 5 at 14,162,185 bp
  • T to A, chromosome 5 at 23,999,991 bp
  • A to G, chromosome 5 at 137,143,995 bp
  • A to G, chromosome 6 at 65,703,070 bp
  • T to C, chromosome 6 at 115,923,883 bp
  • A to G, chromosome 6 at 142,594,722 bp
  • C to G, chromosome 6 at 147,075,191 bp
  • C to T, chromosome 7 at 45,703,525 bp
  • A to G, chromosome 7 at 102,670,402 bp
  • T to C, chromosome 7 at 113,836,813 bp
  • T to A, chromosome 7 at 126,589,475 bp
  • T to A, chromosome 7 at 130,180,457 bp
  • A to G, chromosome 7 at 139,679,316 bp
  • A to T, chromosome 8 at 84,844,119 bp
  • G to A, chromosome 8 at 121,975,997 bp
  • A to T, chromosome 9 at 6,993,942 bp
  • G to A, chromosome 9 at 54,548,369 bp
  • G to A, chromosome 9 at 56,897,403 bp
  • T to A, chromosome 9 at 95,861,456 bp
  • A to T, chromosome 9 at 110,085,273 bp
  • A to G, chromosome 10 at 80,611,141 bp
  • T to A, chromosome 10 at 86,776,252 bp
  • A to T, chromosome 11 at 58,529,411 bp
  • A to G, chromosome 11 at 59,029,377 bp
  • A to C, chromosome 11 at 73,222,931 bp
  • A to C, chromosome 12 at 116,722,172 bp
  • C to T, chromosome 13 at 55,421,533 bp
  • A to C, chromosome 13 at 100,027,433 bp
  • T to C, chromosome 14 at 30,982,427 bp
  • T to A, chromosome 14 at 33,932,043 bp
  • T to A, chromosome 14 at 69,174,677 bp
  • T to C, chromosome 15 at 7,815,649 bp
  • T to A, chromosome 15 at 32,548,799 bp
  • A to T, chromosome 15 at 76,242,070 bp
  • C to T, chromosome 15 at 78,672,368 bp
  • C to T, chromosome 15 at 81,777,067 bp
  • C to A, chromosome 15 at 89,185,337 bp
  • T to C, chromosome 15 at 91,245,815 bp
  • G to A, chromosome 16 at 4,628,233 bp
  • A to G, chromosome 16 at 37,290,927 bp
  • A to T, chromosome 16 at 59,329,244 bp
  • T to C, chromosome 16 at 59,345,427 bp
  • G to A, chromosome 16 at 97,412,135 bp
  • G to T, chromosome 17 at 19,362,252 bp
  • A to T, chromosome 17 at 30,725,124 bp
  • A to G, chromosome 17 at 31,300,521 bp
  • T to C, chromosome 17 at 49,096,577 bp
  • T to C, chromosome 17 at 55,954,479 bp
  • A to G, chromosome 17 at 78,839,100 bp
  • A to G, chromosome 19 at 5,673,315 bp
  • C to T, chromosome 19 at 5,972,848 bp
  • C to T, chromosome 19 at 11,774,595 bp
  • C to T, chromosome 19 at 29,332,068 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1670 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039706-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.