Strain Name:
C57BL/6J-MtgxR1741Btlr/Mmmh
Stock Number:
039773-MU
Citation ID:
RRID:MMRRC_039773-MU
Other Names:
R1741 (G1), C57BL/6J-MtgxR1741Btlr
Major Collection:

Gene Information

Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: FAK, Fadk, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Il21
Name: interleukin 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 60505
HGNC: HGNC:6005
Homologene: 11032
Ip6k1
Name: inositol hexaphosphate kinase 1
Synonyms: Ihpk1, InsP6k1, 1200016D08Rik, InsP6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 27399
Homologene: 56602
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 271639
Homologene: 10188
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: PLU-1, Jarid1b, 2010009J12Rik, Rb-Bp2, D1Ertd202e, Plu1, 2210016I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75605
Homologene: 48448
Ptpn3
Name: protein tyrosine phosphatase, non-receptor type 3
Synonyms: PTP-H1, PTPCL, 9530011I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 545622
HGNC: HGNC:9655
Homologene: 74451
Tmem248
Name: transmembrane protein 248
Synonyms: G430067H08Rik, 0610007L01Rik, A930023A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71667
Homologene: 9951
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Mhdadsk9, Dsk9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Ptbp3
Name: polypyrimidine tract binding protein 3
Synonyms: 5830471K22Rik, Rod1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230257
Homologene: 55872
Zfp64
Name: zinc finger protein 64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22722
Homologene: 7604
Hspa5
Name: heat shock protein 5
Synonyms: Sez7, Bip, D2Wsu17e, D2Wsu141e, Hsce70, XAP-1 antigen, 78kDa, baffled, Grp78, mBiP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14828
HGNC: HGNC:5238
Homologene: 3908
Traf2
Name: TNF receptor-associated factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22030
Homologene: 22520
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Cnot10
Name: CCR4-NOT transcription complex, subunit 10
Synonyms: 2600001P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78893
VEGA: 9
Homologene: 41040
Slc39a14
Name: solute carrier family 39 (zinc transporter), member 14
Synonyms: G630015O18Rik, Zip14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 213053
Homologene: 15037
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234362
Homologene: 74376
Btf3
Name: basic transcription factor 3
Synonyms: 1700054E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218490
HGNC: HGNC:1125
Homologene: 37453
Mapk8ip3
Name: mitogen-activated protein kinase 8 interacting protein 3
Synonyms: Syd2, c-Jun NH2-terminal kinase (JNK)/stress-activated protein kinase-associated protein 1, JSAP1a, JSAP1b, JSAP1c, JSAP1d, JUN/SAPK-associated protein 1, Jip3, JNK-interacting protein 3, JSAP1, D17Wsu15e, sunday driver 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 30957
HGNC: HGNC:6884
Homologene: 22790
Mxra7
Name: matrix-remodelling associated 7
Synonyms: E130302J09Rik, 1810057P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67622
HGNC: HGNC:7541
Homologene: 137378
Ccdc171
Name: coiled-coil domain containing 171
Synonyms: 4930418J05Rik, A330015D16Rik, 4930473A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320226
Homologene: 27942
Dennd2a
Name: DENN/MADD domain containing 2A
Synonyms: B930096L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209773
Homologene: 35238
Pnkd
Name: paroxysmal nonkinesiogenic dyskinesia
Synonyms: 2810403H05Rik, Brp17, 2210013N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 56695
HGNC: HGNC:9153
Homologene: 75045
Adamts13
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms: vWF-CP mRNA for von Willebrand factor-cleaving, LOC279028
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Fam38b, Piezo2, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 667742
Homologene: 49695
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71985
Homologene: 49825
Wdr95
Name: WD40 repeat domain 95
Synonyms: 4930434E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381693
Homologene: 124480
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Trappc11
Name: trafficking protein particle complex 11
Synonyms: D030016E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320714
Homologene: 11076
Chd3
Name: chromodomain helicase DNA binding protein 3
Synonyms: Prp9-1, Chd7, Mi-2 alpha, 2600010P09Rik, Prp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216848
HGNC: HGNC:1918
Homologene: 62693
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319482
Homologene: 130055
Tuba8
Name: tubulin, alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 53857
Homologene: 56766
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56552
Homologene: 135915
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: B230207H15Rik, 1700020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
Eln
Name: elastin
Synonyms: E030024M20Rik, tropoelastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13717
HGNC: HGNC:3327
Scn9a
Name: sodium channel, voltage-gated, type IX, alpha
Synonyms: PN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20274
Homologene: 2237
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: beta3B, Naptb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Actl7a
Name: actin-like 7a
Synonyms: t-actin 2, Tact2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11470
HGNC: HGNC:161
Homologene: 7613
Cblif
Name: cobalamin binding intrinsic factor
Synonyms: Gif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14603
HGNC: HGNC:4268
Homologene: 3773
Gramd4
Name: GRAM domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223752
Homologene: 18199
Rnh1
Name: ribonuclease/angiogenin inhibitor 1
Synonyms: RNH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 107702
Homologene: 2204
Npr2
Name: natriuretic peptide receptor 2
Synonyms: guanylyl cyclase-B, cn, pwe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Hltf
Name: helicase-like transcription factor
Synonyms: Snf2l3, P113, Smarca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20585
Homologene: 30136
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241263
Homologene: 19381
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Txlnb
Name: taxilin beta
Synonyms: Mdp77, 2310001N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 378431
Homologene: 44534
Bcl9l
Name: B cell CLL/lymphoma 9-like
Synonyms: DLNB11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 80288
VEGA: 9
Homologene: 65615
Tmem132d
Name: transmembrane protein 132D
Synonyms: C630028F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243274
Homologene: 71684
Cyp2b23
Name: cytochrome P450, family 2, subfamily b, polypeptide 23
Synonyms: EG243881
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243881
Homologene: 117483
Cox15
Name: cytochrome c oxidase assembly protein 15
Synonyms: 2900026G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226139
HGNC: HGNC:2263
Homologene: 5848
Slc5a1
Name: solute carrier family 5 (sodium/glucose cotransporter), member 1
Synonyms: sodium glucose cotransporter 1, Sglt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20537
Homologene: 55456
Kif21b
Name: kinesin family member 21B
Synonyms: 2610511N21Rik, N-5 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16565
Homologene: 56868
Adam24
Name: a disintegrin and metallopeptidase domain 24 (testase 1)
Synonyms: Dtgn5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13526
HGNC: HGNC:203
Homologene: 137232
Fam83f
Name: family with sequence similarity 83, member F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 213956
VEGA: 15
Homologene: 16313
Wfdc8
Name: WAP four-disulfide core domain 8
Synonyms: LOC277343
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 277343
Homologene: 33799
Hhatl
Name: hedgehog acyltransferase-like
Synonyms: 1110011D13Rik, Gup1, Mitsugumin 56, Mg56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74770
VEGA: 9
Homologene: 19287
Crlf1
Name: cytokine receptor-like factor 1
Synonyms: cytokine receptor like molecule 3, CLF-1, CRLM3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12931
HGNC: HGNC:2364
Homologene: 3489
Pgm1
Name: phosphoglucomutase 1
Synonyms: Pgm1a, 2610020G18Rik, Pgm-2, Pgm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72157
HGNC: HGNC:8905
Homologene: 1979
Sestd1
Name: SEC14 and spectrin domains 1
Synonyms: 1500031J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228071
Homologene: 45505
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pdi4, PAD type IV, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18602
Homologene: 7883
Fez1
Name: fasciculation and elongation protein zeta 1 (zygin I)
Synonyms: UNC-76, UNC76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235180
HGNC: HGNC:3659
Homologene: 21063
Lrrc14b
Name: leucine rich repeat containing 14B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 432779
Homologene: 47758
Glis1
Name: GLIS family zinc finger 1
Synonyms: GliH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230587
Homologene: 77390
Rassf4
Name: Ras association (RalGDS/AF-6) domain family member 4
Synonyms: 3830411C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213391
Homologene: 12926
Nyap1
Name: neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
Synonyms: Nyap1, 6430598A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243300
Homologene: 18320
Ahcy
Name: S-adenosylhomocysteine hydrolase
Synonyms: SAHH, CuBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269378
HGNC: HGNC:343
Homologene: 554
Fbxl21
Name: F-box and leucine-rich repeat protein 21
Synonyms: FBL3B, FBXL3B, Psttm, D630045D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 213311
Homologene: 78724
Gm15409
Name: predicted gene 15409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Gm10277
Name: predicted gene 10277
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 791303
Sftpb
Name: surfactant associated protein B
Synonyms: SP-B, SF-B, Sftp3, Sftp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20388
Homologene: 456
Epor
Name: erythropoietin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13857
VEGA: 9
HGNC: HGNC:3416
Homologene: 95
Btg4
Name: B cell translocation gene 4
Synonyms: PC3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56057
VEGA: 9
Homologene: 9734
1700034E13Rik
Name: RIKEN cDNA 1700034E13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 78414
Homologene: 19041
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 74,347,638 bp
  • A to G, chromosome 1 at 134,618,017 bp
  • C to T, chromosome 1 at 136,156,142 bp
  • T to C, chromosome 1 at 165,543,039 bp
  • A to G, chromosome 2 at 21,827,548 bp
  • T to C, chromosome 2 at 25,524,483 bp
  • T to C, chromosome 2 at 26,973,917 bp
  • T to C, chromosome 2 at 34,772,692 bp
  • T to A, chromosome 2 at 66,487,594 bp
  • A to G, chromosome 2 at 77,192,588 bp
  • T to C, chromosome 2 at 82,989,912 bp
  • G to A, chromosome 2 at 155,064,234 bp
  • T to G, chromosome 2 at 164,608,869 bp
  • A to C, chromosome 2 at 168,926,318 bp
  • T to C, chromosome 3 at 20,086,188 bp
  • T to C, chromosome 3 at 37,227,662 bp
  • G to A, chromosome 4 at 43,643,350 bp
  • A to G, chromosome 4 at 56,744,252 bp
  • A to G, chromosome 4 at 57,254,922 bp
  • A to T, chromosome 4 at 59,482,624 bp
  • A to G, chromosome 4 at 83,620,839 bp
  • G to A, chromosome 4 at 99,964,865 bp
  • G to A, chromosome 4 at 107,568,347 bp
  • A to G, chromosome 4 at 140,746,170 bp
  • A to G, chromosome 5 at 14,676,510 bp
  • A to G, chromosome 5 at 33,133,452 bp
  • T to C, chromosome 5 at 121,647,836 bp
  • A to C, chromosome 5 at 127,784,858 bp
  • A to G, chromosome 5 at 130,236,823 bp
  • A to G, chromosome 5 at 134,729,184 bp
  • A to T, chromosome 5 at 137,733,125 bp
  • C to A, chromosome 5 at 148,959,501 bp
  • G to A, chromosome 5 at 149,595,396 bp
  • A to G, chromosome 6 at 39,493,157 bp
  • C to A, chromosome 6 at 72,305,813 bp
  • T to C, chromosome 6 at 116,639,489 bp
  • T to A, chromosome 6 at 121,222,768 bp
  • T to A, chromosome 6 at 124,061,472 bp
  • A to G, chromosome 7 at 24,990,569 bp
  • A to G, chromosome 7 at 26,673,077 bp
  • G to T, chromosome 7 at 28,157,854 bp
  • A to G, chromosome 7 at 81,467,599 bp
  • A to T, chromosome 7 at 89,851,833 bp
  • C to T, chromosome 7 at 141,164,023 bp
  • T to C, chromosome 8 at 40,679,603 bp
  • A to G, chromosome 8 at 47,529,327 bp
  • C to T, chromosome 8 at 69,611,868 bp
  • C to A, chromosome 8 at 70,500,906 bp
  • C to T, chromosome 9 at 21,959,771 bp
  • T to A, chromosome 9 at 36,843,733 bp
  • T to A, chromosome 9 at 44,509,689 bp
  • A to T, chromosome 9 at 51,116,610 bp
  • G to A, chromosome 9 at 108,040,984 bp
  • T to C, chromosome 9 at 114,597,824 bp
  • T to A, chromosome 9 at 121,789,059 bp
  • A to G, chromosome 10 at 17,838,947 bp
  • A to G, chromosome 11 at 23,364,103 bp
  • A to G, chromosome 11 at 69,355,654 bp
  • TC to T, chromosome 11 at 77,786,002 bp
  • T to C, chromosome 11 at 79,443,931 bp
  • T to G, chromosome 11 at 116,816,244 bp
  • A to T, chromosome 13 at 56,537,102 bp
  • A to G, chromosome 13 at 74,363,586 bp
  • C to T, chromosome 13 at 98,316,296 bp
  • T to C, chromosome 14 at 70,318,744 bp
  • A to G, chromosome 15 at 73,242,406 bp
  • T to G, chromosome 15 at 80,692,267 bp
  • T to C, chromosome 15 at 86,091,529 bp
  • T to C, chromosome 15 at 98,845,234 bp
  • A to G, chromosome 17 at 24,899,854 bp
  • A to G, chromosome 18 at 52,660,506 bp
  • A to G, chromosome 18 at 63,021,173 bp
  • C to T, chromosome 19 at 11,752,185 bp
  • A to G, chromosome 19 at 43,746,931 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1741 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039773-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.