Strain Name:
C57BL/6J-MtgxR1742Btlr/Mmmh
Stock Number:
039774-MU
Citation ID:
RRID:MMRRC_039774-MU
Other Names:
R1742 (G1), C57BL/6J-MtgxR1742Btlr
Major Collection:

Strain Information

Drd2
Name: dopamine receptor D2
Synonyms: Drd-2, D2R, D2 receptor
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13489
VEGA: 9
HGNC: HGNC:3023
Homologene: 22561
Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Atf2
Name: activating transcription factor 2
Synonyms: ATF-2, CRE-BP, mXBP, Creb2, D130078H02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Ptdss2
Name: phosphatidylserine synthase 2
Synonyms: PSS2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 27388
Homologene: 8462
Phf12
Name: PHD finger protein 12
Synonyms: PF1, 2410142K10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268448
Homologene: 10841
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Oxr1
Name: oxidation resistance 1
Synonyms: C7, 2210416C20Rik, C7B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170719
VEGA: 15
Homologene: 24993
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Zic1
Name: zinc finger protein of the cerebellum 1
Synonyms: odd-paired homolog
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22771
Homologene: 2562
Itsn1
Name: intersectin 1 (SH3 domain protein 1A)
Synonyms: Sh3p17, Intersectin-L, EHSH1, Eh domain, SH3 domain regulator of endocytosis 1, Ese1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16443
HGNC: HGNC:6183
Homologene: 2277
Herc4
Name: hect domain and RLD 4
Synonyms: 4921531D01Rik, 1700056O17Rik, 9530080M15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67345
VEGA: 10
Homologene: 56715
Tnks2
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms: Parp5b, 5430432P15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74493
Homologene: 11890
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382034
Homologene: 40964
Rtn4
Name: reticulon 4
Synonyms: 1110020G17Rik, NgA, C130026I10Rik, Nogo-A, Nogo-B, NOGO
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68585
Homologene: 10743
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 360013
Homologene: 7977
Mcph1
Name: microcephaly, primary autosomal recessive 1
Synonyms: D030046N04Rik, 5430437K10Rik, BRIT1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244329
HGNC: HGNC:6954
Homologene: 32586
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Kcnk5
Name: potassium channel, subfamily K, member 5
Synonyms: TASK-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16529
VEGA: 14
HGNC: HGNC:6280
Homologene: 2773
Skic3
Name: SKI3 subunit of superkiller complex
Synonyms: Ttc37
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218343
VEGA: 13
Homologene: 40966
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Lipc
Name: lipase, hepatic
Synonyms: Hpl, HL
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15450
VEGA: 9
HGNC: HGNC:6619
Homologene: 199
Sox8
Name: SRY (sex determining region Y)-box 8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20681
Homologene: 7950
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Clhc1
Name: clathrin heavy chain linker domain containing 1
Synonyms: 1700034F02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73324
Homologene: 17569
Lrrtm1
Name: leucine rich repeat transmembrane neuronal 1
Synonyms: 4632401D06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74342
Homologene: 41763
Fcrl2
Name: Fc receptor like 2
Synonyms: Msr2, Fcrls, Fcrh2, IFGP2, 2810439C17Rik, moFcRH2sc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80891
Homologene: 57117
Smad4
Name: SMAD family member 4
Synonyms: Smad 4, D18Wsu70e, Madh4, Dpc4, DPC4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17128
HGNC: HGNC:6770
Homologene: 31310
Sgta
Name: small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Synonyms: Sgt, D10Ertd190e, 5330427H01Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52551
VEGA: 10
Homologene: 31122
Btf3
Name: basic transcription factor 3
Synonyms: 1700054E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218490
HGNC: HGNC:1125
Homologene: 37453
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: eRFS, 2810035F15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Sass6
Name: SAS-6 centriolar assembly protein
Synonyms: 2810453L12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72776
Homologene: 45668
Ccdc171
Name: coiled-coil domain containing 171
Synonyms: 4930418J05Rik, A330015D16Rik, 4930473A06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320226
Homologene: 27942
Slc44a4
Name: solute carrier family 44, member 4
Synonyms: NG22, 2210409B01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70129
Homologene: 11359
Lemd1
Name: LEM domain containing 1
Synonyms: 6430514M23Rik, LEMP-1, 4930540I23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213409
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase 2, PGHS-2, cyclooxygenase-2, Pghs2, Tis10, Cox-2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Sp8
Name: trans-acting transcription factor 8
Synonyms: mBtd, D930049B17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320145
VEGA: 12
Homologene: 18548
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: SM2, smMHC, SM1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, steerin 3, unc53H3, 9630020C08Rik, 4732483H20Rik, POMFIL1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 260315
Homologene: 56688
Fyttd1
Name: forty-two-three domain containing 1
Synonyms: 2010005M05Rik, 4933423A17Rik, 3830421F13Rik, 3830411L18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69823
Homologene: 12334
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Cryga
Name: crystallin, gamma A
Synonyms: Cryg-4, Secc, DGcry-4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12964
HGNC: HGNC:2408
Homologene: 129704
Dll3
Name: delta like canonical Notch ligand 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13389
HGNC: HGNC:2909
Homologene: 7291
Vwf
Name: Von Willebrand factor
Synonyms: 6820430P06Rik, B130011O06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228602
Homologene: 12623
Accs
Name: 1-aminocyclopropane-1-carboxylate synthase (inactive)
Synonyms: 2610203E10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329470
Homologene: 75335
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546983
Homologene: 115466
Auh
Name: AU RNA binding protein/enoyl-coenzyme A hydratase
Synonyms: W91705
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11992
HGNC: HGNC:890
Homologene: 1284
Arhgef5
Name: Rho guanine nucleotide exchange factor 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54324
Homologene: 66300
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 9130019P20Rik, 4933432B13Rik, A530027J04Rik, 1110004O12Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108857
Homologene: 87006
Ccdc54
Name: coiled-coil domain containing 54
Synonyms: 1700007N18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69339
VEGA: 16
Homologene: 49871
Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Synonyms: Oatp2, Oatp1a4, Slc21a5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28250
Homologene: 130782
Ifi206
Name: interferon activated gene 206
Synonyms: Gm4955, Pyblhin-C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102639543
HGNC: HGNC:5395
Homologene: 115929
Cebpe
Name: CCAAT/enhancer binding protein epsilon
Synonyms: C/EBPepsilon, CRP1, LOC239097, C/EBPe
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110794
VEGA: 14
HGNC: HGNC:1836
Homologene: 1367
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: 2310067L16Rik, C80743
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69700
Homologene: 43567
Dpp10
Name: dipeptidylpeptidase 10
Synonyms: DPRP3, 6430601K09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269109
Homologene: 41400
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232367
Or10ag53
Name: olfactory receptor family 10 subfamily AG member 53
Synonyms: Olfr1530-ps1, MOR264-20, Olfr1115, GA_x6K02T2Q125-48736906-48737886, MOR273-4P, MOR273-4P
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258294
Homologene: 27114
Rgl2
Name: ral guanine nucleotide dissociation stimulator-like 2
Synonyms: Rlf, Rab2l, KE1.5, Rgt2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19732
HGNC: HGNC:9769
Homologene: 3494
Pgbd5
Name: piggyBac transposable element derived 5
Synonyms: 2900019M05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 209966
Homologene: 11583
Nox4
Name: NADPH oxidase 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50490
HGNC: HGNC:7891
Homologene: 41065
Or7g31
Name: olfactory receptor family 7 subfamily G member 31
Synonyms: GA_x6K02T2PVTD-13214162-13213224, MOR147-2, Olfr850
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258516
HGNC: HGNC:8466
Homologene: 121552
Pcdhb17
Name: protocadherin beta 17
Synonyms: Pcdhb16, PcdhbQ
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93888
Homologene: 81881
Coro6
Name: coronin 6
Synonyms: clipin E
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216961
Homologene: 104099
Cr2
Name: complement receptor 2
Synonyms: CD35, C3DR, Cr-1, Cr-2, Cr1, CD21
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Recql
Name: RecQ protein-like
Synonyms: RecQ1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19691
HGNC: HGNC:9948
Homologene: 56279
Iqca1
Name: IQ motif containing with AAA domain 1
Synonyms: 4930465P12Rik, Iqca, 4930585L22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74918
Homologene: 49784
Spata1
Name: spermatogenesis associated 1
Synonyms: 4921536I21Rik, SP-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70951
Homologene: 23356
Pif1
Name: PIF1 5'-to-3' DNA helicase
Synonyms: AI449441
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208084
Homologene: 99775
Taar7a
Name: trace amine-associated receptor 7A
Synonyms: LOC215856, Taar7a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215856
Homologene: 110833
Zfp526
Name: zinc finger protein 526
Synonyms: D030024H03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210172
Homologene: 18447
Or4c123
Name: olfactory receptor family 4 subfamily C member 123
Synonyms: MOR237-1, GA_x6K02T2Q125-50741934-50741017, Olfr1230
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258785
Homologene: 81570
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 54667
Homologene: 23226
Tox2
Name: TOX high mobility group box family member 2
Synonyms: LOC269389, RxHMG1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269389
Homologene: 13155
Plekha3
Name: pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
Synonyms: FAPP1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 83435
Homologene: 10417
Gpr33
Name: G protein-coupled receptor 33
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14762
HGNC: HGNC:4489
Homologene: 7345
Msantd5f6
Name: Myb/SANT DNA binding domain containing 5 family member 6
Synonyms: Gm11487
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433719
Homologene: 128423
Bves
Name: blood vessel epicardial substance
Synonyms: Popdc1, popeye 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23828
VEGA: 10
HGNC: HGNC:1152
Homologene: 48497
Tollip
Name: toll interacting protein
Synonyms: Toll interacting protein, 4930403G24Rik, 4931428G15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54473
Homologene: 10375
Rasl11a
Name: RAS-like, family 11, member A
Synonyms: 1110065D03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68895
Homologene: 45783
Gm15409
Name: predicted gene 15409
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Gm10277
Name: predicted gene 10277
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 791303
2810432D09Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Pgpep1l
Name: pyroglutamyl-peptidase I-like
Synonyms: C330024D12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 78444
Homologene: 25138
CT030687.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 53,456,684 bp
  • C to A, chromosome 1 at 65,103,121 bp
  • T to C, chromosome 1 at 90,098,051 bp
  • T to A, chromosome 1 at 90,813,794 bp
  • A to G, chromosome 1 at 118,964,436 bp
  • T to A, chromosome 1 at 123,445,206 bp
  • A to G, chromosome 1 at 130,845,086 bp
  • T to A, chromosome 1 at 132,228,298 bp
  • A to G, chromosome 1 at 150,104,399 bp
  • G to A, chromosome 1 at 173,481,971 bp
  • A to T, chromosome 1 at 195,158,759 bp
  • A to G, chromosome 2 at 73,819,152 bp
  • G to A, chromosome 2 at 76,682,879 bp
  • T to A, chromosome 2 at 87,252,778 bp
  • G to T, chromosome 2 at 89,296,424 bp
  • A to T, chromosome 2 at 93,841,299 bp
  • A to T, chromosome 2 at 130,740,395 bp
  • G to A, chromosome 2 at 163,225,526 bp
  • A to G, chromosome 2 at 166,866,980 bp
  • T to C, chromosome 3 at 87,259,043 bp
  • A to G, chromosome 3 at 89,952,664 bp
  • T to G, chromosome 3 at 116,607,477 bp
  • A to T, chromosome 3 at 146,469,623 bp
  • T to C, chromosome 4 at 41,712,763 bp
  • T to C, chromosome 4 at 73,401,210 bp
  • T to A, chromosome 4 at 83,681,284 bp
  • T to A, chromosome 5 at 146,846,995 bp
  • C to A, chromosome 5 at 148,959,501 bp
  • T to A, chromosome 6 at 43,280,199 bp
  • C to A, chromosome 6 at 77,244,091 bp
  • T to C, chromosome 6 at 124,200,677 bp
  • T to C, chromosome 6 at 125,667,550 bp
  • T to A, chromosome 6 at 141,825,045 bp
  • T to C, chromosome 6 at 142,364,572 bp
  • A to G, chromosome 7 at 25,224,514 bp
  • T to C, chromosome 7 at 28,294,423 bp
  • A to T, chromosome 7 at 68,237,054 bp
  • T to A, chromosome 7 at 86,795,335 bp
  • T to C, chromosome 7 at 87,295,818 bp
  • A to G, chromosome 7 at 141,130,367 bp
  • C to A, chromosome 7 at 141,892,855 bp
  • G to A, chromosome 8 at 18,607,363 bp
  • T to A, chromosome 8 at 120,566,950 bp
  • T to A, chromosome 8 at 124,380,307 bp
  • T to C, chromosome 9 at 7,503,138 bp
  • A to G, chromosome 9 at 19,478,041 bp
  • T to C, chromosome 9 at 49,400,729 bp
  • T to A, chromosome 9 at 65,587,850 bp
  • A to T, chromosome 9 at 70,820,529 bp
  • T to C, chromosome 9 at 91,361,576 bp
  • T to C, chromosome 10 at 21,347,247 bp
  • G to A, chromosome 10 at 23,993,219 bp
  • C to T, chromosome 10 at 45,347,865 bp
  • C to A, chromosome 10 at 63,287,949 bp
  • T to G, chromosome 10 at 81,046,277 bp
  • T to C, chromosome 10 at 109,769,213 bp
  • T to A, chromosome 11 at 29,557,647 bp
  • T to A, chromosome 11 at 29,733,847 bp
  • C to A, chromosome 11 at 77,467,738 bp
  • TC to T, chromosome 11 at 77,786,002 bp
  • G to T, chromosome 11 at 77,841,467 bp
  • C to T, chromosome 11 at 78,009,486 bp
  • A to G, chromosome 11 at 107,110,951 bp
  • T to C, chromosome 12 at 52,024,262 bp
  • C to T, chromosome 12 at 88,249,683 bp
  • A to G, chromosome 12 at 118,849,817 bp
  • G to A, chromosome 13 at 52,835,496 bp
  • C to T, chromosome 13 at 76,180,038 bp
  • C to T, chromosome 13 at 98,316,296 bp
  • T to A, chromosome 14 at 20,141,857 bp
  • A to G, chromosome 14 at 54,711,600 bp
  • T to C, chromosome 15 at 41,850,559 bp
  • C to T, chromosome 15 at 71,801,913 bp
  • A to T, chromosome 16 at 14,220,044 bp
  • C to T, chromosome 16 at 32,905,553 bp
  • T to C, chromosome 16 at 50,590,238 bp
  • T to G, chromosome 16 at 91,816,959 bp
  • C to T, chromosome 17 at 25,567,941 bp
  • T to A, chromosome 17 at 33,937,223 bp
  • T to C, chromosome 17 at 34,928,411 bp
  • C to A, chromosome 18 at 36,625,265 bp
  • T to C, chromosome 18 at 37,486,576 bp
  • C to T, chromosome 18 at 64,564,329 bp
  • T to C, chromosome 18 at 73,675,897 bp
  • T to C, chromosome 19 at 36,876,261 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1742 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039774-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.