Strain Name:
C57BL/6J-MtgxR1770Btlr/Mmmh
Stock Number:
039801-MU
Citation ID:
RRID:MMRRC_039801-MU
Other Names:
R1770 (G1), C57BL/6J-MtgxR1770Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: Tkrb, C030027L06Rik, trkB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18212
VEGA: 13
HGNC: HGNC:8032
Homologene: 4504
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11287
Homologene: 104112
Ranbp17
Name: RAN binding protein 17
Synonyms: 4932704E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66011
Homologene: 36409
Map1b
Name: microtubule-associated protein 1B
Synonyms: Mtap5, Mtap-5, MAP5, Mtap1b, LC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: Gtar, A130069E23Rik, 4933425K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 81702
Homologene: 82403
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Carmil, Lrrc16, Lrrc16a, 1110037D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68732
Homologene: 9757
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Srrt
Name: serrate RNA effector molecule homolog (Arabidopsis)
Synonyms: Ars2, 2810019G02Rik, Asr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83701
Homologene: 9298
Cstf1
Name: cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms: 1700057K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67337
HGNC: HGNC:2483
Homologene: 1012
Gng4
Name: guanine nucleotide binding protein (G protein), gamma 4
Synonyms: 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14706
HGNC: HGNC:4407
Homologene: 3299
Dcaf13
Name: DDB1 and CUL4 associated factor 13
Synonyms: Wdsof1, LOC223499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223499
Homologene: 6430
Puf60
Name: poly-U binding splicing factor 60
Synonyms: 2410104I19Rik, 2810454F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67959
VEGA: 15
Homologene: 8614
Cep135
Name: centrosomal protein 135
Synonyms: Cep4, LOC381644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381644
Homologene: 45709
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Dcc
Name: deleted in colorectal carcinoma
Synonyms: Igdcc1, C030036D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13176
HGNC: HGNC:2701
Homologene: 21081
C2cd2l
Name: C2 calcium-dependent domain containing 2-like
Synonyms: Tmem24, 1300006O23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71764
VEGA: 9
Homologene: 8876
Ass1
Name: argininosuccinate synthetase 1
Synonyms: ASS, Ass-1, fold
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Msh6
Name: mutS homolog 6
Synonyms: Gtmbp, Msh6, GTBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Wdfy1
Name: WD repeat and FYVE domain containing 1
Synonyms: 1700120F24Rik, 1700013B03Rik, Jr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 69368
Homologene: 10825
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Gtl5, Wcrf180, Acf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, Nte, MSws
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 50767
Homologene: 21333
Zfp142
Name: zinc finger protein 142
Synonyms: 9330177B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77264
Homologene: 3723
Pcdhb16
Name: protocadherin beta 16
Synonyms: Pcdhb8, PcdhbP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93887
HGNC: HGNC:8693
Homologene: 99843
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100604
Homologene: 12997
Trim29
Name: tripartite motif-containing 29
Synonyms: 2810431N19Rik, 4732461M22Rik, 1110047J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72169
VEGA: 9
Homologene: 8100
Myo7a
Name: myosin VIIA
Synonyms: USH1B, Hdb, Myo7, polka, nmf371
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Aldob
Name: aldolase B, fructose-bisphosphate
Synonyms: Aldo-2, Aldo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230163
HGNC: HGNC:417
Homologene: 20060
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Itpr5, Ip3r2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Cntn3
Name: contactin 3
Synonyms: Pang
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18488
HGNC: HGNC:2173
Homologene: 7461
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 637515
Homologene: 19080
Stk10
Name: serine/threonine kinase 10
Synonyms: Lok, Gek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20868
Homologene: 38122
Trpv2
Name: transient receptor potential cation channel, subfamily V, member 2
Synonyms: VRL-1, Vrl1, OTRPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22368
Homologene: 7993
Sdk2
Name: sidekick cell adhesion molecule 2
Synonyms: 4632412F08Rik, 5330435L01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237979
Homologene: 10406
Mdh1b
Name: malate dehydrogenase 1B, NAD (soluble)
Synonyms: 1700124B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 76668
Homologene: 57110
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329628
Homologene: 14377
Prss52
Name: protease, serine 52
Synonyms: 1700049K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 73382
Homologene: 105740
Ugt8a
Name: UDP galactosyltransferase 8A
Synonyms: Cgt, mCerGT, Ugt8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 22239
Homologene: 20715
Kif6
Name: kinesin family member 6
Synonyms: D130004B10Rik, D130084M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 319991
Homologene: 35308
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100121
Homologene: 8618
9330182L06Rik
Name: RIKEN cDNA 9330182L06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231014
Homologene: 27396
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12268
Homologene: 36030
Gns
Name: glucosamine (N-acetyl)-6-sulfatase
Synonyms: G6S, 2610016K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75612
VEGA: 10
HGNC: HGNC:4422
Homologene: 1568
Abcd4
Name: ATP-binding cassette, sub-family D (ALD), member 4
Synonyms: Pxmp1l, P69r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19300
VEGA: 12
HGNC: HGNC:68
Homologene: 3703
Mertk
Name: MER proto-oncogene tyrosine kinase
Synonyms: Mer, Nyk, nmf12, Eyk, Tyro 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17289
HGNC: HGNC:7027
Homologene: 4626
Aldoart1
Name: aldolase 1 A, retrogene 1
Synonyms: Aldoa-ps2, Aldo1-ps2, 4921524E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 353204
Homologene: 128442
Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Synonyms: 2210009K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72303
HGNC: HGNC:2623
Homologene: 133566
Zfp11
Name: zinc finger protein 11
Synonyms: Zfp-11, Krox-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22648
Homologene: 87241
Vmn1r176
Name: vomeronasal 1 receptor 176
Synonyms: Gm5998
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546943
Homologene: 128341
Krt2
Name: keratin 2
Synonyms: Krt2e, Krt2-17, Krt2-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16681
HGNC: HGNC:6439
Mrc2
Name: mannose receptor, C type 2
Synonyms: Endo180, novel lectin, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17534
Homologene: 4408
Klhl35
Name: kelch-like 35
Synonyms: 2810406K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72184
Homologene: 27849
Trim5
Name: tripartite motif-containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667823
Homologene: 75345
Mtmr10
Name: myotubularin related protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233315
Homologene: 9822
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Chml
Name: choroideremia-like
Synonyms: Rep2, E030003F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12663
HGNC: HGNC:1941
Homologene: 31055
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224576
Homologene: 135824
Tas2r115
Name: taste receptor, type 2, member 115
Synonyms: mt2r49, T2R15, Tas2r15, mGR15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 353325
Fastkd5
Name: FAST kinase domains 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 380601
Homologene: 36400
Zfp764
Name: zinc finger protein 764
Synonyms: 8030466O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233893
Homologene: 62158
Dbx2
Name: developing brain homeobox 2
Synonyms: 9430056A22Rik, LOC383001
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223843
Homologene: 54981
Plpbp
Name: pyridoxal phosphate binding protein
Synonyms: Prosc, 2200002F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 114863
HGNC: HGNC:9457
Homologene: 5211
Adgra1
Name: adhesion G protein-coupled receptor A1
Synonyms: 2900059M17Rik, Gpr123, D7Ertd680e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 52389
Homologene: 18582
Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22236
Homologene: 86211
Olfr1148
Name: olfactory receptor 1148
Synonyms: MOR264-7, GA_x6K02T2Q125-49334566-49335510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258220
Homologene: 79465
Mfsd4b1
Name: major facilitator superfamily domain containing 4B1
Synonyms: AI317395
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215929
Homologene: 77426
Mad2l1bp
Name: MAD2L1 binding protein
Synonyms: 0610009D16Rik, 2510031P20Rik, CMT2A, CMT2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66591
VEGA: 17
Homologene: 11990
Gm3852
Name: predicted gene 3852
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100042453
Ndufs5
Name: NADH:ubiquinone oxidoreductase core subunit S5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 595136
HGNC: HGNC:7712
Homologene: 134245
Spryd7
Name: SPRY domain containing 7
Synonyms: 6330409N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66674
Homologene: 10725
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,117,962 bp
  • T to C, chromosome 1 at 46,011,888 bp
  • A to G, chromosome 1 at 63,718,674 bp
  • A to T, chromosome 1 at 74,579,631 bp
  • A to T, chromosome 1 at 79,709,140 bp
  • A to G, chromosome 1 at 88,201,438 bp
  • G to A, chromosome 1 at 175,687,878 bp
  • A to G, chromosome 2 at 31,486,516 bp
  • T to C, chromosome 2 at 76,753,515 bp
  • A to G, chromosome 2 at 87,833,299 bp
  • A to G, chromosome 2 at 128,750,174 bp
  • A to T, chromosome 2 at 130,614,280 bp
  • A to G, chromosome 2 at 172,373,063 bp
  • T to A, chromosome 3 at 39,010,268 bp
  • T to C, chromosome 3 at 125,874,203 bp
  • T to A, chromosome 4 at 45,987,681 bp
  • A to G, chromosome 4 at 49,536,861 bp
  • G to T, chromosome 4 at 72,851,936 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • T to C, chromosome 4 at 123,712,868 bp
  • A to T, chromosome 5 at 9,418,021 bp
  • A to G, chromosome 5 at 76,603,195 bp
  • A to T, chromosome 5 at 90,243,376 bp
  • A to G, chromosome 5 at 105,606,737 bp
  • G to A, chromosome 5 at 129,657,758 bp
  • A to T, chromosome 5 at 137,299,860 bp
  • C to T, chromosome 6 at 102,269,205 bp
  • T to C, chromosome 6 at 128,485,617 bp
  • G to A, chromosome 6 at 132,737,971 bp
  • C to T, chromosome 6 at 146,350,092 bp
  • G to A, chromosome 7 at 23,835,521 bp
  • A to G, chromosome 7 at 64,336,721 bp
  • A to T, chromosome 7 at 98,112,606 bp
  • G to A, chromosome 7 at 99,473,875 bp
  • T to C, chromosome 7 at 104,276,661 bp
  • G to A, chromosome 7 at 127,405,567 bp
  • T to A, chromosome 7 at 139,874,031 bp
  • T to A, chromosome 8 at 3,534,634 bp
  • T to A, chromosome 8 at 27,053,298 bp
  • A to T, chromosome 9 at 43,332,376 bp
  • A to G, chromosome 9 at 44,316,811 bp
  • G to A, chromosome 10 at 12,475,296 bp
  • A to G, chromosome 10 at 40,003,227 bp
  • A to G, chromosome 10 at 121,378,047 bp
  • A to G, chromosome 11 at 32,622,464 bp
  • T to C, chromosome 11 at 33,217,301 bp
  • A to G, chromosome 11 at 62,596,961 bp
  • C to T, chromosome 11 at 71,160,153 bp
  • T to C, chromosome 11 at 105,338,793 bp
  • A to G, chromosome 11 at 113,793,741 bp
  • C to T, chromosome 12 at 54,898,508 bp
  • T to C, chromosome 12 at 84,615,100 bp
  • A to G, chromosome 13 at 13,825,266 bp
  • A to G, chromosome 13 at 24,173,674 bp
  • A to G, chromosome 13 at 58,861,318 bp
  • A to G, chromosome 13 at 96,495,442 bp
  • T to C, chromosome 13 at 99,430,493 bp
  • T to C, chromosome 14 at 61,540,205 bp
  • C to T, chromosome 14 at 64,113,633 bp
  • T to C, chromosome 15 at 23,474,401 bp
  • A to T, chromosome 15 at 39,130,238 bp
  • T to C, chromosome 15 at 76,070,874 bp
  • T to C, chromosome 15 at 95,624,734 bp
  • A to G, chromosome 15 at 101,811,154 bp
  • T to C, chromosome 17 at 20,268,298 bp
  • T to A, chromosome 17 at 34,736,927 bp
  • A to G, chromosome 17 at 46,152,912 bp
  • C to A, chromosome 17 at 49,903,649 bp
  • G to A, chromosome 17 at 87,980,223 bp
  • G to T, chromosome 18 at 37,479,180 bp
  • A to G, chromosome 18 at 71,446,399 bp
  • A to G, chromosome 19 at 39,082,198 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1770 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039801-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.