Strain Name:
C57BL/6J-MtgxR1794Btlr/Mmmh
Stock Number:
039824-MU
Citation ID:
RRID:MMRRC_039824-MU
Other Names:
R1794 (G1), C57BL/6J-MtgxR1794Btlr
Major Collection:

Gene Information

Cntnap2
Name: contactin associated protein-like 2
Synonyms: 5430425M22Rik, Caspr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66797
Homologene: 69159
Notch2
Name: notch 2
Synonyms: Motch B, N2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18129
HGNC: HGNC:7882
Homologene: 7865
Nlgn3
Name: neuroligin 3
Synonyms: NL3, HNL3, A230085M13Rik, NLG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245537
Homologene: 23133
Rnf220
Name: ring finger protein 220
Synonyms: 5730503K05Rik, 4931406I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66743
Homologene: 10036
Plekha7
Name: pleckstrin homology domain containing, family A member 7
Synonyms: A430081P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233765
Homologene: 52172
Lrrc59
Name: leucine rich repeat containing 59
Synonyms: C78668
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 98238
Homologene: 10229
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: Ae2, B3RP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20535
Homologene: 128699
Snrnp200
Name: small nuclear ribonucleoprotein 200 (U5)
Synonyms: A330064G03Rik, Ascc3l1, U5-200KD, HELIC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320632
Homologene: 5859
Cabin1
Name: calcineurin binding protein 1
Synonyms: A330070M20Rik, Ppp3in, Cain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 104248
VEGA: 10
Homologene: 49307
Prrc2c
Name: proline-rich coiled-coil 2C
Synonyms: 9630039I18Rik, Bat2l2, Bat2d, 1810043M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226562
Homologene: 41015
Tex2
Name: testis expressed gene 2
Synonyms: Taz4, 4930568E07Rik, Def-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21763
Homologene: 32414
Tcf4
Name: transcription factor 4
Synonyms: SEF2-1, ITF-2, MITF-2B, MITF-2A, ME2, ITF-2b, ASP-I2, E2-2, TFE, E2.2, SEF-2, 5730422P05Rik, bHLHb19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 21413
Homologene: 2407
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231214
Homologene: 18159
Hsph1
Name: heat shock 105kDa/110kDa protein 1
Synonyms: hsp110/105, HSP110, Hsp105, hsp-E7I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15505
Homologene: 21322
Tjp1
Name: tight junction protein 1
Synonyms: ZO-1, ZO1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21872
Homologene: 2445
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17207
Homologene: 11804
Lman1
Name: lectin, mannose-binding, 1
Synonyms: ERGIC53, 2610020P13Rik, MR60, gp58, F5F8D, MCFD1, P58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70361
HGNC: HGNC:6631
Homologene: 4070
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268878
Homologene: 77451
Cdcp1
Name: CUB domain containing protein 1
Synonyms: 9030022E12Rik, E030027H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109332
Homologene: 11276
Gramd1c
Name: GRAM domain containing 1C
Synonyms: 4921521N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207798
Homologene: 129735
Anxa7
Name: annexin A7
Synonyms: synexin, Anx7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11750
VEGA: 14
HGNC: HGNC:545
Homologene: 36149
Arhgef3
Name: Rho guanine nucleotide exchange factor (GEF) 3
Synonyms: 1200004I24Rik, 9830169H03Rik, C76747
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71704
VEGA: 14
HGNC: HGNC:683
Homologene: 41329
Lins1
Name: lines homolog 1
Synonyms: Lins, 2700083B01Rik, Wins2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72635
Homologene: 10034
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Creb3
Name: cAMP responsive element binding protein 3
Synonyms: LZIP-1, Luman, LZIP, LZIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12913
HGNC: HGNC:2347
Homologene: 31375
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, 9430076A06Rik, D430038H04Rik, LOC382129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Iqch
Name: IQ motif containing H
Synonyms: 4921504K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78250
Homologene: 11258
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, Ushrn, Ush2a, LOC269160, LOC381317, A930037M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 545260
Homologene: 44428
Slc4a3
Name: solute carrier family 4 (anion exchanger), member 3
Synonyms: Ae3, A930038D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20536
Homologene: 129474
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: GlcT-1, Epcs21, Ugcgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22234
Homologene: 37763
Reg3b
Name: regenerating islet-derived 3 beta
Synonyms: Pap, PAP1, REG-III, RegIII (beta)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18489
HGNC: HGNC:8601
Homologene: 130506
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Lox
Name: lysyl oxidase
Synonyms: TSC-160, ras recision gene (rrg)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16948
VEGA: 18
HGNC: HGNC:6664
Homologene: 1741
Ros1
Name: Ros1 proto-oncogene
Synonyms: c-ros, Ros-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Cgn
Name: cingulin
Synonyms: 6330408J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70737
Homologene: 41394
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 213550
Homologene: 15797
Cacna1i
Name: calcium channel, voltage-dependent, alpha 1I subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239556
HGNC: HGNC:1396
Homologene: 69331
Fmnl1
Name: formin-like 1
Synonyms: 8030453N10Rik, formin-related gene in leukocytes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57778
HGNC: HGNC:1212
Homologene: 135620
Cdh4
Name: cadherin 4
Synonyms: Rcad, R-cadherin, R-Cadh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Vmn2r79
Name: vomeronasal 2, receptor 79
Synonyms: EG621430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 621430
Homologene: 115466
Ccl20
Name: chemokine (C-C motif) ligand 20
Synonyms: MIP3A, CKb4, MIP-3A, MIP-3[a], exodus-1, Scya20, ST38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20297
Homologene: 3375
Klhdc7b
Name: kelch domain containing 7B
Synonyms: EG546648
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 546648
Homologene: 34707
Rab7b
Name: RAB7B, member RAS oncogene family
Synonyms: Rab7b, 5430435G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226421
Homologene: 64833
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18080
Homologene: 40632
Map9
Name: microtubule-associated protein 9
Synonyms: 5330427D05Rik, ASAP, Mtap9, 5033421J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213582
Homologene: 41591
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: Rgsl2, 4930415K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268739
Homologene: 19560
Ripk3
Name: receptor-interacting serine-threonine kinase 3
Synonyms: 2610528K09Rik, Rip3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56532
VEGA: 14
Homologene: 31410
Smco1
Name: single-pass membrane protein with coiled-coil domains 1
Synonyms: 2310010M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 69576
Homologene: 18842
Nr2c2ap
Name: nuclear receptor 2C2-associated protein
Synonyms: 2310073E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75692
Homologene: 18532
Btbd2
Name: BTB (POZ) domain containing 2
Synonyms: 2610037C03Rik, 4930512K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 208198
Homologene: 32365
Olfr1449
Name: olfactory receptor 1449
Synonyms: MOR202-34, GA_x6K02T2RE5P-3264213-3265157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258300
Homologene: 17184
Fam219b
Name: family with sequence similarity 219, member B
Synonyms: 2310046O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78323
VEGA: 9
Homologene: 10721
Olfr1263
Name: olfactory receptor 1263
Synonyms: GA_x6K02T2Q125-51447049-51447969, MOR234-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258790
Homologene: 45043
Lrrc27
Name: leucine rich repeat containing 27
Synonyms: 1700071K18Rik, 2310044E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76612
Homologene: 19268
Marchf1
Name: membrane associated ring-CH-type finger 1
Synonyms: 2900024D24Rik, March1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72925
Homologene: 113749
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKK-i, IKKepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56489
Homologene: 23168
Hhat
Name: hedgehog acyltransferase
Synonyms: Skn, Tg(TFAP2A-cre)1Will, 2810432O22Rik, AP-2CRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226861
Homologene: 41232
Wdr38
Name: WD repeat domain 38
Synonyms: 1700123D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76646
Homologene: 79011
Vmn1r203
Name: vomeronasal 1 receptor 203
Synonyms: V1rh11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171270
Homologene: 110880
Rgs20
Name: regulator of G-protein signaling 20
Synonyms: 2900073E09Rik, Rgsz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 58175
Homologene: 2745
Brdt
Name: bromodomain, testis-specific
Synonyms: Fsrg3, 7420412D09Rik, Brd6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 114642
HGNC: HGNC:1105
Homologene: 21064
Zswim2
Name: zinc finger SWIM-type containing 2
Synonyms: 4933437F18Rik, MEX, 1700025P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71861
Homologene: 32689
Tmem50b
Name: transmembrane protein 50B
Synonyms: B230114J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77975
HGNC: HGNC:1280
Homologene: 21234
Lingo3
Name: leucine rich repeat and Ig domain containing 3
Synonyms: LERN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237403
VEGA: 10
Homologene: 78065
Klk1b7-ps
Name: kallikrein 1-related peptidase b7, pseudogene
Synonyms: Klk-ps2, mGK-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16604
Slc22a7
Name: solute carrier family 22 (organic anion transporter), member 7
Synonyms: NLT, OAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 108114
VEGA: 17
Homologene: 21328
Pate7
Name: prostate and testis expressed 7
Synonyms: Gm17727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100312986
Homologene: 129804
1700014D04Rik
Name: RIKEN cDNA 1700014D04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 102638268
Homologene: 140986
Zfp248
Name: zinc finger protein 248
Synonyms: 2810037F07Rik, E130106N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72720
Homologene: 69325
Gm9991
Name: predicted gene 9991
Synonyms: EG433332
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433332
Samd13
Name: sterile alpha motif domain containing 13
Synonyms: LOC381481
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Tmem203
Name: transmembrane protein 203
Synonyms: C730025P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227615
Homologene: 107047
Gm4792
Name: predicted gene 4792
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215472
Znrf4
Name: zinc and ring finger 4
Synonyms: spzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20834
VEGA: 17
Homologene: 7959
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 4,910,572 bp
  • A to T, chromosome 1 at 75,557,308 bp
  • T to A, chromosome 1 at 83,117,829 bp
  • A to G, chromosome 1 at 90,679,093 bp
  • T to A, chromosome 1 at 131,259,218 bp
  • T to C, chromosome 1 at 131,697,068 bp
  • A to G, chromosome 1 at 150,598,285 bp
  • G to A, chromosome 1 at 150,627,152 bp
  • A to G, chromosome 1 at 153,838,194 bp
  • T to C, chromosome 1 at 162,705,959 bp
  • T to C, chromosome 1 at 188,862,809 bp
  • G to T, chromosome 1 at 192,693,906 bp
  • A to G, chromosome 2 at 25,255,994 bp
  • A to G, chromosome 2 at 39,000,729 bp
  • T to C, chromosome 2 at 66,303,720 bp
  • A to G, chromosome 2 at 83,918,009 bp
  • A to G, chromosome 2 at 90,015,020 bp
  • A to G, chromosome 2 at 127,216,736 bp
  • C to T, chromosome 2 at 179,886,842 bp
  • A to G, chromosome 3 at 82,380,221 bp
  • A to G, chromosome 3 at 94,762,557 bp
  • A to G, chromosome 3 at 98,099,547 bp
  • T to A, chromosome 3 at 146,662,797 bp
  • A to G, chromosome 4 at 43,563,302 bp
  • C to T, chromosome 4 at 59,207,798 bp
  • G to T, chromosome 4 at 117,307,568 bp
  • A to G, chromosome 5 at 24,439,328 bp
  • C to A, chromosome 5 at 43,688,252 bp
  • ACAGCAGCAGCAGCAGC to ACAGCAGCAGCAGC, chromosome 5 at 107,359,853 bp
  • A to T, chromosome 5 at 149,630,773 bp
  • T to C, chromosome 6 at 45,991,863 bp
  • T to C, chromosome 6 at 73,024,958 bp
  • G to T, chromosome 6 at 78,372,214 bp
  • A to G, chromosome 6 at 118,429,303 bp
  • A to G, chromosome 7 at 43,945,223 bp
  • A to T, chromosome 7 at 65,323,129 bp
  • T to C, chromosome 7 at 66,711,909 bp
  • G to A, chromosome 7 at 87,001,413 bp
  • T to C, chromosome 7 at 105,771,720 bp
  • A to G, chromosome 7 at 116,140,681 bp
  • G to T, chromosome 7 at 139,238,563 bp
  • C to A, chromosome 7 at 139,238,565 bp
  • T to C, chromosome 8 at 12,915,982 bp
  • T to A, chromosome 8 at 66,386,942 bp
  • T to G, chromosome 8 at 70,131,908 bp
  • A to T, chromosome 9 at 15,997,136 bp
  • A to T, chromosome 9 at 15,997,138 bp
  • T to A, chromosome 9 at 35,777,122 bp
  • A to G, chromosome 9 at 57,539,281 bp
  • A to G, chromosome 9 at 63,482,557 bp
  • A to C, chromosome 9 at 64,317,776 bp
  • G to A, chromosome 9 at 108,965,928 bp
  • A to G, chromosome 9 at 123,190,094 bp
  • T to C, chromosome 9 at 123,215,831 bp
  • T to A, chromosome 10 at 52,124,103 bp
  • A to C, chromosome 10 at 75,725,745 bp
  • G to T, chromosome 10 at 80,643,913 bp
  • C to A, chromosome 10 at 80,835,598 bp
  • T to C, chromosome 10 at 94,298,490 bp
  • T to C, chromosome 11 at 94,638,595 bp
  • T to C, chromosome 11 at 103,197,147 bp
  • T to C, chromosome 11 at 106,567,902 bp
  • G to A, chromosome 12 at 70,043,795 bp
  • C to T, chromosome 13 at 22,524,351 bp
  • T to C, chromosome 13 at 59,742,620 bp
  • A to G, chromosome 14 at 20,471,467 bp
  • A to G, chromosome 14 at 27,397,605 bp
  • G to T, chromosome 14 at 51,989,930 bp
  • G to T, chromosome 14 at 55,785,329 bp
  • A to G, chromosome 15 at 47,603,616 bp
  • G to A, chromosome 15 at 80,389,122 bp
  • T to C, chromosome 15 at 89,387,020 bp
  • C to A, chromosome 16 at 29,321,709 bp
  • A to G, chromosome 16 at 32,274,132 bp
  • T to C, chromosome 16 at 43,986,915 bp
  • T to C, chromosome 16 at 91,578,029 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • T to G, chromosome 17 at 46,433,153 bp
  • A to G, chromosome 17 at 56,511,599 bp
  • A to G, chromosome 18 at 52,528,307 bp
  • G to A, chromosome 18 at 60,916,651 bp
  • T to C, chromosome 18 at 65,991,684 bp
  • T to A, chromosome 18 at 69,657,853 bp
  • G to C, chromosome 19 at 12,934,968 bp
  • A to G, chromosome 19 at 29,299,557 bp
  • A to G, chromosome X at 101,320,033 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1794 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039824-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.