Strain Name:
C57BL/6J-MtgxR1796Btlr/Mmmh
Stock Number:
039826-MU
Citation ID:
RRID:MMRRC_039826-MU
Other Names:
R1796 (G1), C57BL/6J-MtgxR1796Btlr
Major Collection:

Gene Information

Gene Symbol: Kif3c [MGI:107979] (Mus musculus (mouse))
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Chromosome: 12
Alteration at locus: Chemically Induced
Gene Symbol: Xrcc1 [MGI:99137] (Mus musculus (mouse))
Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Synonyms: Xrcc-1
Chromosome: 7
Alteration at locus: Chemically Induced
Gene Symbol: Adgre1 [MGI:106912] (Mus musculus (mouse))
Name: adhesion G protein-coupled receptor E1
Synonyms: TM7LN3, EGF-TM7, DD7A5-7, F4/80, Emr1, Ly71
Chromosome: 17
Alteration at locus: Chemically Induced
Gene Symbol: Enc1 [MGI:109610] (Mus musculus (mouse))
Name: ectodermal-neural cortex 1
Synonyms: PIG10, Nrpb
Chromosome: 13
Alteration at locus: Chemically Induced
Gene Symbol: Pik3cd [MGI:1098211] (Mus musculus (mouse))
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Synonyms: 2410099E07Rik, p110delta, 2610208K16Rik
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Ece1 [MGI:1101357] (Mus musculus (mouse))
Name: endothelin converting enzyme 1
Chromosome: 4
Alteration at locus: Chemically Induced
Gene Symbol: Rtel1 [MGI:2139369] (Mus musculus (mouse))
Name: regulator of telomere elongation helicase 1
Chromosome: 2
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,500,033 bp
  • C to T, chromosome 1 at 74,918,948 bp
  • A to G, chromosome 1 at 105,731,284 bp
  • T to C, chromosome 1 at 150,375,554 bp
  • A to T, chromosome 1 at 163,045,710 bp
  • G to T, chromosome 1 at 175,637,895 bp
  • A to T, chromosome 1 at 175,717,331 bp
  • A to C, chromosome 1 at 188,910,827 bp
  • C to T, chromosome 2 at 25,577,988 bp
  • G to T, chromosome 2 at 84,615,209 bp
  • A to C, chromosome 2 at 90,898,706 bp
  • A to G, chromosome 2 at 126,652,433 bp
  • A to T, chromosome 2 at 145,848,888 bp
  • G to A, chromosome 2 at 151,938,989 bp
  • G to A, chromosome 2 at 153,401,606 bp
  • A to T, chromosome 2 at 154,560,929 bp
  • A to T, chromosome 2 at 155,992,187 bp
  • A to T, chromosome 2 at 164,580,311 bp
  • T to A, chromosome 2 at 181,352,103 bp
  • G to T, chromosome 3 at 14,143,433 bp
  • C to T, chromosome 3 at 20,223,227 bp
  • A to G, chromosome 3 at 54,373,756 bp
  • A to T, chromosome 3 at 55,643,708 bp
  • T to A, chromosome 3 at 90,203,698 bp
  • A to G, chromosome 3 at 108,701,850 bp
  • A to G, chromosome 3 at 116,539,825 bp
  • G to T, chromosome 3 at 116,634,947 bp
  • A to T, chromosome 4 at 8,221,671 bp
  • T to A, chromosome 4 at 43,770,495 bp
  • T to A, chromosome 4 at 131,865,071 bp
  • T to A, chromosome 4 at 133,313,753 bp
  • T to C, chromosome 4 at 134,094,984 bp
  • C to T, chromosome 4 at 137,958,001 bp
  • T to C, chromosome 4 at 139,428,596 bp
  • G to A, chromosome 4 at 147,613,283 bp
  • A to G, chromosome 4 at 149,654,119 bp
  • T to A, chromosome 4 at 156,169,211 bp
  • A to G, chromosome 5 at 9,116,489 bp
  • T to G, chromosome 5 at 23,986,151 bp
  • T to C, chromosome 5 at 37,383,075 bp
  • T to C, chromosome 5 at 110,295,319 bp
  • T to C, chromosome 5 at 113,273,617 bp
  • T to A, chromosome 5 at 143,173,447 bp
  • A to G, chromosome 6 at 41,968,162 bp
  • T to C, chromosome 6 at 57,323,271 bp
  • A to T, chromosome 6 at 57,900,149 bp
  • C to A, chromosome 6 at 70,960,810 bp
  • T to C, chromosome 6 at 88,836,619 bp
  • T to C, chromosome 6 at 146,296,673 bp
  • A to G, chromosome 7 at 24,547,827 bp
  • C to T, chromosome 7 at 28,155,372 bp
  • T to C, chromosome 7 at 45,280,755 bp
  • T to A, chromosome 7 at 67,734,000 bp
  • A to T, chromosome 7 at 85,563,803 bp
  • T to C, chromosome 7 at 106,752,549 bp
  • A to T, chromosome 8 at 13,836,816 bp
  • T to C, chromosome 8 at 120,085,418 bp
  • A to T, chromosome 8 at 121,560,438 bp
  • C to A, chromosome 9 at 19,137,917 bp
  • A to G, chromosome 9 at 20,351,930 bp
  • T to C, chromosome 9 at 21,947,375 bp
  • T to A, chromosome 9 at 38,855,524 bp
  • C to T, chromosome 9 at 39,796,005 bp
  • A to G, chromosome 9 at 39,873,971 bp
  • T to A, chromosome 9 at 42,384,197 bp
  • A to T, chromosome 9 at 66,388,856 bp
  • A to T, chromosome 9 at 110,550,345 bp
  • A to T, chromosome 9 at 110,617,816 bp
  • A to T, chromosome 9 at 115,248,607 bp
  • A to T, chromosome 9 at 116,719,333 bp
  • A to T, chromosome 10 at 40,647,629 bp
  • G to A, chromosome 10 at 52,025,228 bp
  • T to C, chromosome 10 at 81,467,219 bp
  • G to A, chromosome 10 at 81,589,497 bp
  • T to C, chromosome 10 at 93,745,771 bp
  • A to T, chromosome 11 at 8,444,021 bp
  • T to A, chromosome 11 at 29,881,975 bp
  • T to A, chromosome 11 at 43,491,287 bp
  • C to A, chromosome 11 at 59,029,337 bp
  • T to C, chromosome 11 at 67,224,357 bp
  • T to A, chromosome 11 at 67,260,324 bp
  • C to T, chromosome 11 at 74,085,845 bp
  • T to C, chromosome 11 at 77,829,344 bp
  • T to C, chromosome 11 at 82,981,955 bp
  • A to T, chromosome 11 at 84,091,968 bp
  • A to G, chromosome 11 at 94,507,551 bp
  • T to A, chromosome 11 at 97,336,556 bp
  • A to G, chromosome 12 at 3,367,299 bp
  • A to T, chromosome 12 at 28,594,859 bp
  • T to C, chromosome 12 at 69,300,297 bp
  • G to A, chromosome 12 at 84,615,382 bp
  • G to T, chromosome 12 at 103,142,746 bp
  • A to T, chromosome 12 at 103,984,695 bp
  • A to T, chromosome 12 at 108,812,913 bp
  • T to C, chromosome 12 at 116,317,817 bp
  • T to A, chromosome 13 at 24,997,128 bp
  • A to G, chromosome 13 at 57,430,431 bp
  • C to T, chromosome 13 at 62,171,856 bp
  • A to G, chromosome 13 at 77,044,043 bp
  • T to C, chromosome 13 at 81,531,715 bp
  • T to A, chromosome 13 at 97,246,483 bp
  • C to A, chromosome 13 at 97,246,485 bp
  • T to A, chromosome 14 at 31,261,093 bp
  • C to T, chromosome 14 at 60,020,758 bp
  • A to C, chromosome 15 at 75,901,175 bp
  • C to T, chromosome 15 at 80,690,082 bp
  • A to G, chromosome 15 at 99,696,654 bp
  • A to G, chromosome 15 at 101,742,880 bp
  • T to C, chromosome 15 at 101,781,552 bp
  • T to A, chromosome 15 at 101,950,865 bp
  • A to G, chromosome 16 at 32,143,511 bp
  • A to T, chromosome 16 at 48,874,247 bp
  • T to C, chromosome 17 at 27,890,071 bp
  • C to T, chromosome 17 at 32,332,483 bp
  • A to G, chromosome 17 at 34,267,372 bp
  • T to C, chromosome 17 at 35,083,502 bp
  • T to C, chromosome 17 at 48,309,502 bp
  • A to G, chromosome 17 at 57,441,350 bp
  • A to T, chromosome 17 at 73,830,359 bp
  • A to G, chromosome 17 at 84,599,133 bp
  • C to T, chromosome 18 at 31,986,675 bp
  • C to T, chromosome 18 at 77,405,907 bp
  • G to A, chromosome 18 at 77,425,639 bp
  • T to C, chromosome 18 at 84,851,561 bp
  • T to G, chromosome 19 at 4,287,940 bp
  • A to G, chromosome 19 at 18,827,567 bp
  • T to C, chromosome 19 at 46,503,019 bp
  • T to C, chromosome 19 at 56,837,783 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1796 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039826-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials and based on the transfer success rate of the MMRRC facility) to transfer to at least two recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.