Strain Name:
C57BL/6J-MtgxR1842Btlr/Mmmh
Stock Number:
039867-MU
Citation ID:
RRID:MMRRC_039867-MU
Other Names:
R1842 (G1), C57BL/6J-MtgxR1842Btlr
Major Collection:

Gene Information

Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20562
Homologene: 2302
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Cep55
Name: centrosomal protein 55
Synonyms: 2700032M20Rik, 1200008O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Aopep
Name: aminopeptidase O
Synonyms: ApO, 2010111I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72061
HGNC: HGNC:1361
Homologene: 66273
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Cenpm
Name: centromere protein M
Synonyms: 2610019I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66570
VEGA: 15
Homologene: 11438
Wdr7
Name: WD repeat domain 7
Synonyms: TGF-beta resistance associated gene, TRAG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104082
VEGA: 18
Homologene: 11408
Ctdp1
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Synonyms: 4930563P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67655
HGNC: HGNC:2498
Homologene: 31254
Hspa5
Name: heat shock protein 5
Synonyms: Hsce70, Bip, Grp78, Sez7, D2Wsu141e, D2Wsu17e, 78kDa, mBiP, XAP-1 antigen, baffled
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14828
HGNC: HGNC:5238
Homologene: 3908
Eif2d
Name: eukaryotic translation initiation factor 2D
Synonyms: D1Ertd5e, Lgtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16865
HGNC: HGNC:6583
Homologene: 38244
Abr
Name: active BCR-related gene
Synonyms: 6330400K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 109934
HGNC: HGNC:81
Homologene: 11081
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: RU2, Dcdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 195208
Homologene: 9483
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Kansl3
Name: KAT8 regulatory NSL complex subunit 3
Synonyms: 4632411B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226976
Homologene: 9949
Flrt2
Name: fibronectin leucine rich transmembrane protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 399558
HGNC: HGNC:3761
Homologene: 8291
Il17f
Name: interleukin 17F
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 257630
Homologene: 17115
Gad1
Name: glutamate decarboxylase 1
Synonyms: GAD67, Gad-1, Z49976, EP10, GAD44, GAD25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14415
HGNC: HGNC:4092
Homologene: 635
Tomm40
Name: translocase of outer mitochondrial membrane 40
Synonyms: Tom40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53333
Homologene: 101105
Necap1
Name: NECAP endocytosis associated 1
Synonyms: 1200016B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67602
Homologene: 22902
Nutf2
Name: nuclear transport factor 2
Synonyms: 2700067I02Rik, PP15, Ntf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 68051
Homologene: 110745
Nsun6
Name: NOL1/NOP2/Sun domain family member 6
Synonyms: 4933403D21Rik, NOPD1, 4933414E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74455
Homologene: 12564
Fbxo34
Name: F-box protein 34
Synonyms: 5830426G16Rik, 2900057B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78938
VEGA: 14
Homologene: 12713
Nsun3
Name: NOL1/NOP2/Sun domain family member 3
Synonyms: 6720484A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106338
Homologene: 65358
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
Mfsd14a
Name: major facilitator superfamily domain containing 14A
Synonyms: Hiat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15247
Homologene: 22456
Peg10
Name: paternally expressed 10
Synonyms: MEF3L, HB-1, MyEF-3, MyEF-3 like, Edr, Mart2, Mar2, Rtl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170676
Homologene: 116067
Rab38
Name: RAB38, member RAS oncogene family
Synonyms: 2310011F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72433
HGNC: HGNC:9776
Homologene: 21353
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Map4k1
Name: mitogen-activated protein kinase kinase kinase kinase 1
Synonyms: Hpk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26411
HGNC: HGNC:6863
Homologene: 5199
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Elf3
Name: E74-like factor 3
Synonyms: jen, ESX, ESE-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13710
HGNC: HGNC:3318
Homologene: 3265
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna-1, erythroid, ihj, Spna1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20739
Homologene: 74460
Kdm5d
Name: lysine (K)-specific demethylase 5D
Synonyms: Smcy, Jarid1d, HY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 20592
Homologene: 55838
Olfr352
Name: olfactory receptor 352
Synonyms: GA_x6K02T2NLDC-33564136-33565083, MOR136-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258942
Homologene: 121523
Lrp2bp
Name: Lrp2 binding protein
Synonyms: MegBP, 4930479L12Rik, 1700113N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67620
Homologene: 10183
Scube3
Name: signal peptide, CUB domain, EGF-like 3
Synonyms: D030038I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268935
Homologene: 65059
Gbp6
Name: guanylate binding protein 6
Synonyms: Mpa2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100702
Homologene: 128731
Mast3
Name: microtubule associated serine/threonine kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 546071
Homologene: 66191
Egflam
Name: EGF-like, fibronectin type III and laminin G domains
Synonyms: nectican, pikachurin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268780
Homologene: 65044
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212392
Homologene: 17668
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Odad2
Name: outer dynein arm docking complex subunit 2
Synonyms: 4930463I21Rik, Armc4, b2b227.1Clo, b2b643Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 74934
VEGA: 18
Homologene: 9992
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Dhh
Name: desert hedgehog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13363
VEGA: 15
HGNC: HGNC:2865
Homologene: 22431
Krt26
Name: keratin 26
Synonyms: 4732407F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 320864
Homologene: 37118
Ccdc30
Name: coiled-coil domain containing 30
Synonyms: 1700111D19Rik, 4930445I03Rik, 1700001O02Rik, 1700041C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 73332
Homologene: 137391
Rgsl1
Name: regulator of G-protein signaling like 1
Synonyms: 4930415K13Rik, Rgsl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240816
Homologene: 129962
Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, Endo180, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17534
Homologene: 4408
Efcab5
Name: EF-hand calcium binding domain 5
Synonyms: 4930563A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319634
Homologene: 63366
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
Fam110a
Name: family with sequence similarity 110, member A
Synonyms: 1700008J10Rik, 5430432M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73847
Homologene: 12862
Hapln2
Name: hyaluronan and proteoglycan link protein 2
Synonyms: 4930401E20Rik, Bral1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73940
Homologene: 11045
Glb1l
Name: galactosidase, beta 1-like
Synonyms: 4833408P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74577
Homologene: 75208
Hcn1
Name: hyperpolarization activated cyclic nucleotide gated potassium channel 1
Synonyms: HAC2, Bcng1, C630013B14Rik, hyperpolarization-activated, cyclic nucleotide-gated K+ 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15165
HGNC: HGNC:4845
Homologene: 32093
Slc18b1
Name: solute carrier family 18, subfamily B, member 1
Synonyms: 1110021L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76306
Homologene: 33473
Klra6
Name: killer cell lectin-like receptor, subfamily A, member 6
Synonyms: Ly49F, Ly49f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16637
Homologene: 110821
Gpam
Name: glycerol-3-phosphate acyltransferase, mitochondrial
Synonyms: GPAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14732
Homologene: 7343
Timm44
Name: translocase of inner mitochondrial membrane 44
Synonyms: Tim44, Mimt44, D8Ertd118e, 0710005E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21856
Homologene: 4631
Vmn2r23
Name: vomeronasal 2, receptor 23
Synonyms: EG435916
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435916
Homologene: 135826
Sgpp1
Name: sphingosine-1-phosphate phosphatase 1
Synonyms: mSPP1, SPP1, SPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 81535
VEGA: 12
Homologene: 101696
Gsta2
Name: glutathione S-transferase, alpha 2 (Yc2)
Synonyms: Gstc-2, Gst2-2, Gstc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14858
Homologene: 74378
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: 9230107O05Rik, D1Mgi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Ccdc28b
Name: coiled coil domain containing 28B
Synonyms: 1110002E08Rik, 1810010N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66264
Homologene: 11509
4930562F07Rik
Name: RIKEN cDNA 4930562F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75255
Arhgap27
Name: Rho GTPase activating protein 27
Synonyms: 2310069I04Rik, 5730442P18Rik, Sh3d20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544817
Homologene: 45715
1700014D04Rik
Name: RIKEN cDNA 1700014D04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 102638268
Homologene: 140986
Olfr1166
Name: olfactory receptor 1166
Synonyms: GA_x6K02T2Q125-49616865-49615915, MOR174-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258644
Homologene: 138307
Mettl5
Name: methyltransferase like 5
Synonyms: 2810410A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75422
Homologene: 8570
Zscan2
Name: zinc finger and SCAN domain containing 2
Synonyms: Zfp-29, Zfp29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22691
Homologene: 56453
Frg2f1
Name: FSHD region gene 2 family member 1
Synonyms: AA415398
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433752
Homologene: 86332
Gm10770
Name: predicted gene 10770
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 544945
VEGA: 2
Alms1-ps2
Name: ALMS1, centrosome and basal body associated, pseudogene 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 623273
Tex45
Name: testis expressed 45
Synonyms: 1700019B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76406
Homologene: 52367
E030025P04Rik
Name: RIKEN cDNA E030025P04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268498
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,784,167 bp
  • A to C, chromosome 1 at 21,487,212 bp
  • A to G, chromosome 1 at 34,164,119 bp
  • A to G, chromosome 1 at 36,351,744 bp
  • A to G, chromosome 1 at 75,200,460 bp
  • C to A, chromosome 1 at 131,171,060 bp
  • T to C, chromosome 1 at 135,256,793 bp
  • T to A, chromosome 1 at 153,799,797 bp
  • T to C, chromosome 1 at 160,077,505 bp
  • T to C, chromosome 1 at 164,184,560 bp
  • T to A, chromosome 1 at 165,503,243 bp
  • A to G, chromosome 1 at 174,195,947 bp
  • A to T, chromosome 2 at 15,009,477 bp
  • A to G, chromosome 2 at 34,775,803 bp
  • A to T, chromosome 2 at 36,869,589 bp
  • G to T, chromosome 2 at 69,885,342 bp
  • G to T, chromosome 2 at 70,574,253 bp
  • A to T, chromosome 2 at 88,124,127 bp
  • G to A, chromosome 2 at 150,179,156 bp
  • A to T, chromosome 2 at 151,970,034 bp
  • C to T, chromosome 3 at 5,401,498 bp
  • A to G, chromosome 3 at 88,024,001 bp
  • A to T, chromosome 3 at 116,632,408 bp
  • T to C, chromosome 4 at 119,331,127 bp
  • A to T, chromosome 4 at 119,531,080 bp
  • T to A, chromosome 4 at 129,621,013 bp
  • T to C, chromosome 5 at 105,277,736 bp
  • A to T, chromosome 6 at 4,756,381 bp
  • T to C, chromosome 6 at 85,796,249 bp
  • A to G, chromosome 6 at 122,874,588 bp
  • T to A, chromosome 6 at 123,729,690 bp
  • T to C, chromosome 6 at 130,022,610 bp
  • A to G, chromosome 7 at 19,713,725 bp
  • T to C, chromosome 7 at 28,987,163 bp
  • A to T, chromosome 7 at 80,760,883 bp
  • A to C, chromosome 7 at 80,875,553 bp
  • G to A, chromosome 7 at 88,450,522 bp
  • T to A, chromosome 8 at 3,483,668 bp
  • A to G, chromosome 8 at 4,260,510 bp
  • A to T, chromosome 8 at 45,940,568 bp
  • A to G, chromosome 8 at 46,011,115 bp
  • A to G, chromosome 8 at 70,780,393 bp
  • T to C, chromosome 8 at 105,876,610 bp
  • A to G, chromosome 9 at 78,331,262 bp
  • T to C, chromosome 10 at 23,805,993 bp
  • A to G, chromosome 10 at 127,573,468 bp
  • T to A, chromosome 11 at 76,508,986 bp
  • A to G, chromosome 11 at 77,134,875 bp
  • G to A, chromosome 11 at 94,359,612 bp
  • CTAGTA to CTA, chromosome 11 at 99,333,526 bp
  • C to A, chromosome 11 at 103,339,996 bp
  • A to G, chromosome 11 at 105,337,720 bp
  • G to A, chromosome 11 at 109,139,570 bp
  • G to T, chromosome 11 at 110,197,039 bp
  • C to G, chromosome 12 at 8,011,559 bp
  • T to C, chromosome 12 at 16,696,243 bp
  • C to T, chromosome 12 at 75,716,208 bp
  • T to C, chromosome 12 at 95,779,284 bp
  • T to C, chromosome 13 at 25,107,602 bp
  • G to A, chromosome 13 at 55,246,445 bp
  • T to C, chromosome 13 at 59,742,506 bp
  • T to G, chromosome 13 at 63,298,871 bp
  • T to C, chromosome 13 at 117,976,008 bp
  • A to G, chromosome 14 at 47,531,007 bp
  • A to G, chromosome 15 at 7,303,941 bp
  • T to C, chromosome 15 at 82,239,364 bp
  • T to C, chromosome 15 at 98,894,560 bp
  • T to C, chromosome 16 at 20,171,238 bp
  • A to T, chromosome 16 at 62,776,392 bp
  • G to A, chromosome 17 at 28,165,089 bp
  • A to G, chromosome 18 at 5,062,373 bp
  • A to T, chromosome 18 at 7,223,551 bp
  • A to G, chromosome 18 at 63,935,834 bp
  • A to T, chromosome 18 at 80,451,326 bp
  • T to C, chromosome 19 at 5,155,884 bp
  • A to T, chromosome 19 at 5,725,930 bp
  • T to A, chromosome 19 at 9,005,867 bp
  • A to G, chromosome 19 at 38,057,900 bp
  • A to T, chromosome 19 at 41,721,038 bp
  • A to G, chromosome 19 at 55,087,372 bp
  • C to T, chromosome Y at 927,798 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1842 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039867-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.