Strain Name:
C57BL/6J-MtgxR1846Btlr/Mmmh
Stock Number:
039871-MU
Citation ID:
RRID:MMRRC_039871-MU
Other Names:
R1846 (G1), C57BL/6J-MtgxR1846Btlr
Major Collection:

Gene Information

Adamts20
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Synonyms: ADAMTS-20, bt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223838
Homologene: 11808
Sufu
Name: SUFU negative regulator of hedgehog signaling
Synonyms: Su(Fu), b2b273Clo, 2810026F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24069
Homologene: 9262
Ppp1r17
Name: protein phosphatase 1, regulatory subunit 17
Synonyms: G-substrate, Gsbs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19051
Homologene: 4849
Anks3
Name: ankyrin repeat and sterile alpha motif domain containing 3
Synonyms: 2700067D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72615
VEGA: 16
Homologene: 12475
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 9530077A04Rik, D230038D11Rik, 1810033J14Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Dnmbp
Name: dynamin binding protein
Synonyms: Tuba, 2410003L07Rik, 2410003M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71972
Homologene: 9061
Anxa4
Name: annexin A4
Synonyms: Anx4, annexin IV, AIV, Xanx-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11746
HGNC: HGNC:542
Homologene: 68164
Pafah2
Name: platelet-activating factor acetylhydrolase 2
Synonyms: 2310074E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100163
HGNC: HGNC:8579
Homologene: 37309
Rorb
Name: RAR-related orphan receptor beta
Synonyms: Nr1f2, RZR-beta, Rorbeta, hstp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225998
Homologene: 38250
Smg7
Name: Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 9430023P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226517
Homologene: 32235
Rad23b
Name: RAD23 homolog B, nucleotide excision repair protein
Synonyms: 0610007D13Rik, mHR23B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19359
HGNC: HGNC:9813
Homologene: 37704
Gars
Name: glycyl-tRNA synthetase
Synonyms: Sgrp23, Gena201, GENA202
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 353172
HGNC: HGNC:4162
Homologene: 1547
Fbxo28
Name: F-box protein 28
Synonyms: 5730505P19Rik, 4833428J17Rik, D1Ertd578e, Fbx28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67948
Homologene: 9050
Metap1
Name: methionyl aminopeptidase 1
Synonyms: 1700029C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75624
Homologene: 6488
Cep170
Name: centrosomal protein 170
Synonyms: 4933426L22Rik, A330004A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545389
Homologene: 22844
Zgrf1
Name: zinc finger, GRF-type containing 1
Synonyms: 4930422G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71643
Homologene: 34708
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Polr1a
Name: polymerase (RNA) I polypeptide A
Synonyms: Rpo1-4, RPA194, 2900087K15Rik, 194kDa, mRPA1, 3010014K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20019
Homologene: 7033
Bub1
Name: BUB1, mitotic checkpoint serine/threonine kinase
Synonyms: Bub1a, D2Xrf87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12235
HGNC: HGNC:1148
Homologene: 37910
Fasn
Name: fatty acid synthase
Synonyms: A630082H08Rik, FAS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Gmnn
Name: geminin
Synonyms: Gem
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 57441
Homologene: 9292
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 64898
Homologene: 8769
Lamb2
Name: laminin, beta 2
Synonyms: npht, Lams, Lamb-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16779
HGNC: HGNC:6487
Homologene: 1723
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC333789, B3bp, LOC386488
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Zbtb40
Name: zinc finger and BTB domain containing 40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230848
Homologene: 8912
Gcfc2
Name: GC-rich sequence DNA binding factor 2
Synonyms: AW146020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330361
HGNC: HGNC:1317
Homologene: 2411
Zfp318
Name: zinc finger protein 318
Synonyms: TZF, D530032D06Rik, 2610034E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 57908
Homologene: 22808
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Eif4e3
Name: eukaryotic translation initiation factor 4E member 3
Synonyms: eIF4E-3, 1300018P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66892
Homologene: 41652
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7a, LOC381341, Dnahc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 627872
Homologene: 41287
Nup85
Name: nucleoporin 85
Synonyms: Pcnt1, frount
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 445007
HGNC: HGNC:8734
Homologene: 11755
Ptk7
Name: PTK7 protein tyrosine kinase 7
Synonyms: 8430404F20Rik, chz, mPTK7/CCK4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71461
VEGA: 17
HGNC: HGNC:9618
Homologene: 43672
Htt
Name: huntingtin
Synonyms: IT15, huntingtin, htt, C430023I11Rik, Hdh, HD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, Kif10, CENP-E, 312kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Cars2
Name: cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
Synonyms: 2310051N18Rik, D530030H10Rik, 2410044A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71941
Homologene: 11575
Entpd3
Name: ectonucleoside triphosphate diphosphohydrolase 3
Synonyms: NTPDase-3, HB6, Cd39l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215446
HGNC: HGNC:3365
Homologene: 68171
Ern2
Name: endoplasmic reticulum (ER) to nucleus signalling 2
Synonyms: Ire1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26918
Homologene: 22687
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Ttn
Name: titin
Synonyms: D830007G01Rik, L56, 1100001C23Rik, mdm, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, shru, connectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
2900092C05Rik
Name: RIKEN cDNA 2900092C05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73090
Homologene: 49900
Chia1
Name: chitinase, acidic 1
Synonyms: AMCase, Chia, YNL, 2200003E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Arhgef25
Name: Rho guanine nucleotide exchange factor (GEF) 25
Synonyms: D10Ertd610e, 2410008H17Rik, GEFT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52666
VEGA: 10
Homologene: 32691
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: V2Rp4, EG638102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 638102
Homologene: 86604
Plpp6
Name: phospholipid phosphatase 6
Synonyms: 4932443D16Rik, Ppapdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74411
Homologene: 45228
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, Heatr7b1, OTTMUSG00000020804
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Olfr1258
Name: olfactory receptor 1258
Synonyms: GA_x6K02T2Q125-51361752-51362687, MOR232-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258980
Homologene: 82299
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
Synonyms: LH-R, Lhr, Gpcr19-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16867
VEGA: 17
HGNC: HGNC:6585
Homologene: 37276
Fbln2
Name: fibulin 2
Synonyms: 5730577E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14115
HGNC: HGNC:3601
Homologene: 1514
Zfp628
Name: zinc finger protein 628
Synonyms: Zec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232816
Homologene: 72200
Parp2
Name: poly (ADP-ribose) polymerase family, member 2
Synonyms: Adprt2, C78626, Aspartl2, Adprtl2, PARP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11546
VEGA: 14
HGNC: HGNC:272
Homologene: 4004
Mpeg1
Name: macrophage expressed gene 1
Synonyms: Mpg-1, Perforin-2, MPS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17476
VEGA: 19
Homologene: 11216
Glp1r
Name: glucagon-like peptide 1 receptor
Synonyms: GLP-1R, GLP1Rc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14652
VEGA: 17
HGNC: HGNC:4324
Homologene: 1558
Vmn2r62
Name: vomeronasal 2, receptor 62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546964
Homologene: 104832
Krt87
Name: keratin 87
Synonyms: Krt2-25, Krt83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406219
VEGA: 15
Homologene: 133804
Usp4
Name: ubiquitin specific peptidase 4 (proto-oncogene)
Synonyms: F730026I20Rik, Unp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22258
Homologene: 20716
Tph1
Name: tryptophan hydroxylase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21990
Homologene: 121565
Thsd7b
Name: thrombospondin, type I, domain containing 7B
Synonyms: 1700074E13Rik, D130067I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210417
Homologene: 18180
Ssbp2
Name: single-stranded DNA binding protein 2
Synonyms: 2310079I02Rik, 1500004K09Rik, 9330163K02Rik, Hspc116, A830008M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66970
Homologene: 22724
Col17a1
Name: collagen, type XVII, alpha 1
Synonyms: BPAg2, BP180, Bpag2, Bpag
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12821
HGNC: HGNC:2194
Homologene: 7276
Stt3a
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
Synonyms: Itm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16430
HGNC: HGNC:6172
Homologene: 40617
Polrmt
Name: polymerase (RNA) mitochondrial (DNA directed)
Synonyms: 1110018N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216151
HGNC: HGNC:9200
Homologene: 37996
Krt36
Name: keratin 36
Synonyms: keratin 5, Krt1-5, Krt1-22, HRa-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Bglap2
Name: bone gamma-carboxyglutamate protein 2
Synonyms: mOC-B, bone Gla protein, osteocalcin, OG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12097
HGNC: HGNC:1043
Homologene: 104130
Rusc1
Name: RUN and SH3 domain containing 1
Synonyms: 2210403N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72296
Homologene: 75028
Fez1
Name: fasciculation and elongation protein zeta 1 (zygin I)
Synonyms: UNC76, UNC-76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235180
HGNC: HGNC:3659
Homologene: 21063
Hspa14
Name: heat shock protein 14
Synonyms: NST-1, 70kDa, Hsp70-4, HSP70L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50497
Homologene: 74307
Olfr1415
Name: olfactory receptor 1415
Synonyms: MOR103-12, GA_x6K02T2R7CC-81266841-81267776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258228
Homologene: 79367
Igsf21
Name: immunoglobulin superfamily, member 21
Synonyms: LOC230868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230868
Homologene: 13153
Zfp174
Name: zinc finger protein 174
Synonyms: LOC385674
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 385674
Homologene: 55755
Ggt5
Name: gamma-glutamyltransferase 5
Synonyms: GGL, Ggtla1, gamma-glutamyl leukotrienase, GGT-REL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 23887
HGNC: HGNC:4260
Homologene: 55802
Vmn1r8
Name: vomeronasal 1 receptor 8
Synonyms: V1rc32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171205
Homologene: 83427
Prl7b1
Name: prolactin family 7, subfamily b, member 1
Synonyms: Prlpn, 1600014J19Rik, PLP-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75596
Homologene: 17809
Olfr448
Name: olfactory receptor 448
Synonyms: MOR261-13, GA_x6K02T2P3E9-4663051-4662119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258270
HGNC: HGNC:8232
Homologene: 64846
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
ccdc198
Name: coiled-coil domain containing 198
Synonyms: 1700011H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67082
Homologene: 49528
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 53,647,334 bp
  • A to G, chromosome 1 at 88,258,664 bp
  • A to T, chromosome 1 at 92,491,100 bp
  • G to A, chromosome 1 at 129,613,256 bp
  • A to G, chromosome 1 at 152,848,850 bp
  • C to T, chromosome 1 at 176,755,769 bp
  • T to C, chromosome 1 at 182,326,280 bp
  • T to C, chromosome 2 at 3,491,660 bp
  • A to G, chromosome 2 at 76,945,686 bp
  • A to G, chromosome 2 at 89,930,666 bp
  • A to G, chromosome 2 at 127,829,589 bp
  • A to G, chromosome 3 at 38,982,383 bp
  • A to G, chromosome 3 at 88,378,625 bp
  • T to C, chromosome 3 at 89,092,145 bp
  • T to A, chromosome 3 at 106,130,865 bp
  • T to A, chromosome 3 at 127,615,463 bp
  • T to A, chromosome 3 at 135,239,845 bp
  • A to G, chromosome 3 at 138,480,682 bp
  • C to T, chromosome 4 at 55,383,637 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • GCCCC to GCCCCC, chromosome 4 at 134,425,541 bp
  • T to C, chromosome 4 at 137,007,839 bp
  • T to A, chromosome 4 at 140,067,126 bp
  • A to T, chromosome 5 at 8,988,248 bp
  • G to A, chromosome 5 at 23,499,486 bp
  • T to A, chromosome 5 at 34,848,944 bp
  • T to C, chromosome 5 at 65,808,519 bp
  • A to G, chromosome 6 at 42,897,320 bp
  • A to G, chromosome 6 at 55,063,168 bp
  • A to G, chromosome 6 at 56,022,427 bp
  • A to G, chromosome 6 at 57,036,428 bp
  • T to C, chromosome 6 at 71,976,188 bp
  • A to T, chromosome 6 at 81,956,892 bp
  • T to A, chromosome 6 at 86,741,911 bp
  • C to A, chromosome 6 at 91,256,417 bp
  • T to C, chromosome 6 at 99,640,701 bp
  • C to T, chromosome 7 at 4,920,867 bp
  • G to A, chromosome 7 at 12,512,882 bp
  • G to A, chromosome 7 at 42,789,122 bp
  • A to T, chromosome 7 at 46,660,439 bp
  • T to G, chromosome 7 at 122,176,536 bp
  • A to G, chromosome 8 at 11,514,674 bp
  • T to C, chromosome 8 at 61,983,958 bp
  • C to T, chromosome 9 at 36,763,385 bp
  • T to C, chromosome 9 at 36,867,767 bp
  • A to G, chromosome 9 at 108,372,736 bp
  • G to A, chromosome 9 at 108,487,387 bp
  • G to A, chromosome 9 at 120,558,375 bp
  • T to C, chromosome 10 at 27,212,096 bp
  • A to G, chromosome 10 at 75,610,542 bp
  • A to T, chromosome 10 at 79,738,209 bp
  • T to C, chromosome 10 at 103,025,304 bp
  • A to G, chromosome 10 at 127,185,864 bp
  • C to A, chromosome 11 at 100,105,548 bp
  • A to G, chromosome 11 at 115,568,413 bp
  • A to G, chromosome 11 at 120,813,307 bp
  • T to A, chromosome 12 at 40,733,268 bp
  • C to A, chromosome 13 at 24,760,149 bp
  • A to T, chromosome 13 at 27,602,848 bp
  • A to G, chromosome 13 at 46,848,391 bp
  • C to T, chromosome 13 at 91,664,149 bp
  • G to T, chromosome 14 at 49,235,963 bp
  • T to A, chromosome 14 at 50,815,386 bp
  • A to T, chromosome 15 at 94,345,990 bp
  • C to T, chromosome 15 at 101,434,566 bp
  • C to A, chromosome 16 at 3,854,735 bp
  • A to C, chromosome 16 at 4,953,884 bp
  • T to A, chromosome 16 at 32,752,369 bp
  • A to C, chromosome 17 at 23,359,383 bp
  • A to G, chromosome 17 at 30,929,935 bp
  • T to A, chromosome 17 at 46,413,666 bp
  • A to G, chromosome 17 at 46,576,490 bp
  • A to G, chromosome 17 at 71,225,069 bp
  • C to T, chromosome 17 at 88,765,147 bp
  • T to C, chromosome 19 at 12,463,122 bp
  • C to T, chromosome 19 at 18,955,081 bp
  • T to C, chromosome 19 at 28,964,280 bp
  • T to C, chromosome 19 at 43,902,747 bp
  • T to A, chromosome 19 at 46,450,947 bp
  • T to C, chromosome 19 at 47,670,388 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1846 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
039871-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.