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Strain Name:
C57BL/6J-MtgxR1972Btlr/Mmmh
Stock Number:
039985-MU
Citation ID:
RRID:MMRRC_039985-MU
Other Names:
R1972 (G1), C57BL/6J-MtgxR1972Btlr
Major Collection:

Strain Information

Rpl13a
Name: ribosomal protein L13A
Synonyms: tum-antigen, tum-transplantation antigen P198, Tstap198-7, 1810026N22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22121
Homologene: 111053
Chrm4
Name: cholinergic receptor, muscarinic 4
Synonyms: Chrm-4, muscarinic acetylcholine receptor 4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12672
HGNC: HGNC:1953
Homologene: 20192
Chat
Name: choline O-acetyltransferase
Synonyms: B230380D24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12647
VEGA: 14
HGNC: HGNC:1912
Homologene: 40693
Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Synonyms: SHIP, Src homology 2 domain-containing inositol-5-phosphatase, s-SHIP, SHIP-1, SHIP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16331
HGNC: HGNC:6079
Homologene: 4046
Mthfr
Name: methylenetetrahydrofolate reductase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17769
HGNC: HGNC:7436
Homologene: 4349
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Pnn
Name: pinin
Synonyms: D12Ertd512e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18949
VEGA: 12
HGNC: HGNC:9162
Homologene: 37656
Morf4l1
Name: mortality factor 4 like 1
Synonyms: TEG-189, MRG15, MORFRG15, Tex189
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21761
Homologene: 86043
Rorb
Name: RAR-related orphan receptor beta
Synonyms: Nr1f2, RZR-beta, Rorbeta, hstp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225998
Homologene: 38250
Stk4
Name: serine/threonine kinase 4
Synonyms: Ysk3, Kas-2, Mst1, sterile 20-like kinase 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 58231
Homologene: 55965
Dennd2c
Name: DENN domain containing 2C
Synonyms: A930010I20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329727
Homologene: 19542
Scaf8
Name: SR-related CTD-associated factor 8
Synonyms: A930036P18Rik, A630086M08Rik, Rbm16
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106583
VEGA: 17
Homologene: 8928
Prr11
Name: proline rich 11
Synonyms: B930067F20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 270906
Homologene: 10123
Rfx5
Name: regulatory factor X, 5 (influences HLA class II expression)
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 53970
HGNC: HGNC:9986
Tigar
Name: Trp53 induced glycolysis regulatory phosphatase
Synonyms: Tigar, 9630033F20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319801
HGNC: HGNC:1185
Homologene: 32473
Borcs5
Name: BLOC-1 related complex subunit 5
Synonyms: 5830457J20Rik, Loh12cr1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67774
Homologene: 12188
Smndc1
Name: survival motor neuron domain containing 1
Synonyms: 4933440I19Rik, 2410004J23Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76479
VEGA: 19
Homologene: 4290
Bmpr2
Name: bone morphogenetic protein receptor type 2
Synonyms: BMPR-II, BMP-2, 2610024H22Rik, BMPRII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12168
HGNC: HGNC:1078
Homologene: 929
Adat1
Name: adenosine deaminase, tRNA-specific 1
Synonyms: mADAT1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 30947
HGNC: HGNC:228
Homologene: 8096
Slc18a2
Name: solute carrier family 18 (vesicular monoamine), member 2
Synonyms: Vmat2, 1110037L13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 214084
VEGA: 19
Homologene: 2298
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: ICRFP703N2430Q5.1, ICRFP703B1614Q5.1, 4932442O19Rik, Cegf1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56788
Homologene: 36383
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 404710
Homologene: 26400
Eif2ak1
Name: eukaryotic translation initiation factor 2 alpha kinase 1
Synonyms: Hri
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15467
Homologene: 8290
Rbm43
Name: RNA binding motif protein 43
Synonyms: 0610033I05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71684
Homologene: 12715
Nop2
Name: NOP2 nucleolar protein
Synonyms: 120kDa, Nol1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110109
HGNC: HGNC:7867
Homologene: 135865
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: Ten-m3, 2610100B16Rik, Odz3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Pdlim1
Name: PDZ and LIM domain 1 (elfin)
Synonyms: mClim1, CLP36
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54132
HGNC: HGNC:2067
Homologene: 9643
Pithd1
Name: PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
Synonyms: 1110049F12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66193
Homologene: 10678
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: 8030475K17Rik, A330041G23Rik, 2610202E01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Tmc2
Name: transmembrane channel-like gene family 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192140
Homologene: 25877
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: MDHC7, E030034C22Rik, B230373P09Rik, Dnahc1, G1-415-19, ferf1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Marco
Name: macrophage receptor with collagenous structure
Synonyms: Scara2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17167
HGNC: HGNC:6895
Homologene: 4928
Ttll7
Name: tubulin tyrosine ligase-like family, member 7
Synonyms: 1110049N09Rik, 4921517B04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70892
Homologene: 41578
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208169
Homologene: 19505
2900092C05Rik
Name: RIKEN cDNA 2900092C05 gene
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73090
Homologene: 49900
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Sis
Name: sucrase isomaltase
Synonyms: Si-s, sucrase-isomaltase, 2010204N08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69983
Homologene: 37424
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: vascular endothelial growth factor receptor-1, VEGFR-1, VEGFR1, Flt-1, sFlt1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192188
Homologene: 23022
Or5ac25
Name: olfactory receptor family 5 subfamily AC member 25
Synonyms: GA_x54KRFPKG5P-55590495-55589578, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55580232-55579315, Olfr208, Olfr209, MOR182-9, GA_x54KRFPKG5P-55570276-55569359, Olfr207
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404311
Homologene: 133040
Cdh7
Name: cadherin 7, type 2
Synonyms: CDH7L1, 9330156F07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241201
HGNC: HGNC:1766
Homologene: 68391
Il17ra
Name: interleukin 17 receptor A
Synonyms: VDw217, Il17r
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16172
HGNC: HGNC:5985
Homologene: 7378
Arhgef11
Name: Rho guanine nucleotide exchange factor 11
Synonyms: PDZ-RhoGEF, Prg
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213498
Homologene: 11409
Cap2
Name: cyclase associated actin cytoskeleton regulatory protein 2
Synonyms: 2810452G09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67252
Homologene: 101397
Sec22c
Name: SEC22 homolog C, vesicle trafficking protein
Synonyms: 5930407I15Rik, Sec22l3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215474
Homologene: 41948
Vmn2r82
Name: vomeronasal 2, receptor 82
Synonyms: EG624845
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 624845
Homologene: 83483
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Pde1a
Name: phosphodiesterase 1A, calmodulin-dependent
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18573
HGNC: HGNC:8774
Homologene: 21043
Gsdma2
Name: gasdermin A2
Synonyms: 2210411P14Rik, 2210009F20Rik, 2200001G21Rik, Gsdml2, 2210006M16Rik, Gsdm2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76758
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Or10x1
Name: olfactory receptor family 10 subfamily X member 1
Synonyms: GA_x6K02T2P20D-20787051-20786119, MOR267-11, Olfr417
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258238
Homologene: 17358
Serpinb11
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
Synonyms: 2310046M08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66957
Homologene: 41653
Isoc2a
Name: isochorismatase domain containing 2a
Synonyms: Isoc2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 664994
Homologene: 86122
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Cyp2d22
Name: cytochrome P450, family 2, subfamily d, polypeptide 22
Synonyms: 2D22
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 56448
VEGA: 15
Homologene: 75003
Or2ag12
Name: olfactory receptor family 2 subfamily AG member 12
Synonyms: GA_x6K02T2PBJ9-9055944-9054994, MOR283-8, Olfr693
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258445
Lgmn
Name: legumain
Synonyms: preprolegumain, Prsc1, AEP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 19141
HGNC: HGNC:9472
Homologene: 38075
Neil2
Name: nei like 2 (E. coli)
Synonyms: LOC382913, NEH2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 382913
VEGA: 14
Homologene: 17032
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 626596
Homologene: 75047
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: Snep, 6720455I24Rik, D430044C15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208777
Homologene: 14708
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 215384
Homologene: 68369
Nod2
Name: nucleotide-binding oligomerization domain containing 2
Synonyms: F830032C23Rik, Card15, Nlrc2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 257632
HGNC: HGNC:5331
Homologene: 11156
Xkr5
Name: X-linked Kx blood group related 5
Synonyms: 5430438H03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319581
Homologene: 52219
Ift56
Name: intraflagellar transport 56
Synonyms: hpy, hydrocephalic-polydactyl, 9430097H08Rik, hop, Ttc26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 264134
Homologene: 11786
Or4c113
Name: olfactory receptor family 4 subfamily C member 113
Synonyms: GA_x6K02T2Q125-50536041-50535106, MOR233-12, Olfr1218
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258815
Homologene: 73986
Or8b40
Name: olfactory receptor family 8 subfamily B member 40
Synonyms: GA_x6K02T2PVTD-31795028-31795957, MOR162-2, Olfr889
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258475
Homologene: 138311
Klra9
Name: killer cell lectin-like receptor subfamily A, member 9
Synonyms: Ly49I, LY49I1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16640
Homologene: 110821
Nlrx1
Name: NLR family member X1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270151
VEGA: 9
Homologene: 11623
Or5b119
Name: olfactory receptor family 5 subfamily B member 119
Synonyms: GA_x6K02T2RE5P-3812807-3811863, MOR202-36, Olfr1475
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258298
Homologene: 77370
Spatc1
Name: spermatogenesis and centriole associated 1
Synonyms: 1700084J23Rik, speriolin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74281
VEGA: 15
Homologene: 129861
Nuak2
Name: NUAK family, SNF1-like kinase, 2
Synonyms: 1200013B22Rik, Snark
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74137
Homologene: 12539
Ugt1a10
Name: UDP glycosyltransferase 1 family, polypeptide A10
Synonyms: A13
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394430
Homologene: 133281
Gpr149
Name: G protein-coupled receptor 149
Synonyms: PGR10, 9630018L10Rik, Ieda, R35
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229357
Homologene: 16359
Entrep2
Name: endosomal transmembrane epsin interactor 2
Synonyms: 5730507A09Rik, Fam189a1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70638
Homologene: 77705
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
Bbs2
Name: Bardet-Biedl syndrome 2
Synonyms: 2410125H22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67378
HGNC: HGNC:967
Homologene: 12122
Or52e8
Name: olfactory receptor family 52 subfamily E member 8
Synonyms: GA_x6K02T2PBJ9-7604826-7603885, MOR32-12, Olfr671
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257910
Homologene: 133595
Heatr4
Name: HEAT repeat containing 4
Synonyms: Gm17673
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 101055670
Homologene: 45728
Ccdc113
Name: coiled-coil domain containing 113
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244608
Homologene: 40927
Kcnk12
Name: potassium channel, subfamily K, member 12
Synonyms: mntk1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210741
VEGA: 17
HGNC: HGNC:6274
Homologene: 11107
Tbc1d30
Name: TBC1 domain family, member 30
Synonyms: 4930505D03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74694
VEGA: 10
Homologene: 18930
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 59,813,603 bp
  • T to C, chromosome 1 at 87,676,314 bp
  • A to T, chromosome 1 at 88,056,047 bp
  • G to A, chromosome 1 at 93,265,073 bp
  • T to C, chromosome 1 at 107,369,480 bp
  • G to A, chromosome 1 at 110,061,132 bp
  • A to G, chromosome 1 at 120,504,662 bp
  • A to T, chromosome 1 at 132,330,602 bp
  • T to C, chromosome 1 at 174,369,570 bp
  • A to T, chromosome 2 at 51,925,536 bp
  • T to C, chromosome 2 at 79,865,721 bp
  • A to T, chromosome 2 at 89,054,547 bp
  • C to T, chromosome 2 at 91,927,493 bp
  • T to A, chromosome 2 at 130,214,664 bp
  • C to T, chromosome 2 at 164,100,528 bp
  • T to C, chromosome 3 at 62,530,795 bp
  • A to G, chromosome 3 at 72,921,004 bp
  • T to C, chromosome 3 at 87,727,509 bp
  • T to A, chromosome 3 at 88,083,928 bp
  • C to T, chromosome 3 at 94,957,292 bp
  • C to T, chromosome 3 at 96,651,738 bp
  • A to C, chromosome 3 at 97,207,202 bp
  • T to C, chromosome 3 at 103,131,698 bp
  • T to C, chromosome 3 at 146,939,962 bp
  • T to C, chromosome 4 at 135,987,029 bp
  • T to C, chromosome 4 at 148,051,927 bp
  • A to G, chromosome 5 at 143,884,714 bp
  • G to A, chromosome 5 at 147,655,093 bp
  • C to A, chromosome 6 at 38,410,803 bp
  • A to G, chromosome 6 at 120,482,216 bp
  • A to G, chromosome 6 at 125,134,639 bp
  • A to G, chromosome 6 at 127,087,926 bp
  • A to T, chromosome 6 at 130,182,382 bp
  • A to G, chromosome 6 at 134,710,174 bp
  • T to A, chromosome 7 at 4,892,087 bp
  • A to G, chromosome 7 at 12,550,592 bp
  • A to T, chromosome 7 at 28,094,192 bp
  • T to A, chromosome 7 at 45,125,995 bp
  • A to T, chromosome 7 at 64,775,768 bp
  • T to C, chromosome 7 at 104,975,899 bp
  • T to C, chromosome 7 at 106,678,219 bp
  • A to T, chromosome 7 at 109,809,214 bp
  • C to T, chromosome 8 at 18,941,981 bp
  • T to C, chromosome 8 at 48,228,591 bp
  • A to T, chromosome 8 at 88,652,873 bp
  • A to G, chromosome 8 at 94,081,177 bp
  • A to T, chromosome 8 at 95,538,246 bp
  • A to G, chromosome 8 at 111,990,418 bp
  • T to A, chromosome 9 at 38,116,567 bp
  • A to G, chromosome 9 at 44,253,456 bp
  • A to T, chromosome 9 at 90,095,214 bp
  • A to G, chromosome 9 at 101,211,777 bp
  • A to T, chromosome 9 at 121,688,254 bp
  • A to G, chromosome 10 at 79,378,846 bp
  • A to T, chromosome 10 at 86,960,316 bp
  • T to C, chromosome 10 at 88,551,542 bp
  • A to T, chromosome 10 at 121,306,230 bp
  • C to T, chromosome 10 at 128,720,466 bp
  • G to A, chromosome 11 at 87,098,754 bp
  • T to C, chromosome 11 at 98,650,918 bp
  • T to C, chromosome 12 at 59,070,532 bp
  • T to A, chromosome 12 at 83,955,020 bp
  • A to G, chromosome 12 at 102,395,821 bp
  • A to G, chromosome 13 at 46,637,899 bp
  • A to G, chromosome 13 at 100,212,770 bp
  • C to T, chromosome 14 at 31,265,391 bp
  • C to T, chromosome 14 at 32,424,191 bp
  • G to A, chromosome 14 at 34,065,811 bp
  • A to T, chromosome 14 at 63,186,077 bp
  • T to A, chromosome 15 at 36,103,836 bp
  • A to T, chromosome 15 at 76,284,875 bp
  • A to T, chromosome 15 at 82,375,827 bp
  • A to G, chromosome 16 at 45,593,472 bp
  • A to T, chromosome 16 at 59,362,113 bp
  • T to G, chromosome 17 at 3,169,371 bp
  • T to C, chromosome 17 at 87,797,132 bp
  • T to C, chromosome 19 at 13,479,694 bp
  • T to A, chromosome 19 at 18,952,203 bp
  • A to T, chromosome 19 at 40,223,137 bp
  • A to C, chromosome 19 at 53,383,555 bp
  • T to A, chromosome 19 at 56,357,353 bp
  • A to G, chromosome 19 at 59,274,653 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1972 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039985-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.