Strain Name:
C57BL/6J-MtgxR2054Btlr/Mmmh
Stock Number:
040059-MU
Citation ID:
RRID:MMRRC_040059-MU
Other Names:
R2054 (G1), C57BL/6J-MtgxR2054Btlr
Major Collection:

Gene Information

Pkd1
Name: polycystin 1, transient receptor poteintial channel interacting
Synonyms: PC1, PC-1, polycystin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Ccnd1
Name: cyclin D1
Synonyms: CycD1, cD1, Cyl-1, PRAD1, bcl-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12443
HGNC: HGNC:1582
Homologene: 1334
Itch
Name: itchy, E3 ubiquitin protein ligase
Synonyms: 8030492O04Rik, 6720481N21Rik, C230047C07Rik, AIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16396
Homologene: 88442
Fiz1
Name: Flt3 interacting zinc finger protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23877
Homologene: 22663
Tead4
Name: TEA domain family member 4
Synonyms: Rtef1, TEAD-4, Tcf13r1, Tefr1a, ETFR-2a, Tef3, TEF-3, Tefr, Etfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21679
Homologene: 74463
Traip
Name: TRAF-interacting protein
Synonyms: Trip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22036
Homologene: 31343
Tti1
Name: TELO2 interacting protein 1
Synonyms: 2610036D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75425
Homologene: 40969
Smc2
Name: structural maintenance of chromosomes 2
Synonyms: CAP-E, 5730502P04Rik, Smc2l1, Fin16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14211
Homologene: 4705
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, Frap1, RAPT1, RAFT1, mechanistic target of rapamycin (serine/threonine kinase), flat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: Mll, Mll1, All1, HTRX1, ALL-1, trithorax Drosophila, Cxxc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Nol9
Name: nucleolar protein 9
Synonyms: 4632412I24Rik, 6030462G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74035
Homologene: 32589
Clcn7
Name: chloride channel, voltage-sensitive 7
Synonyms: ClC-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 26373
HGNC: HGNC:2025
Homologene: 56546
Zfp64
Name: zinc finger protein 64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22722
Homologene: 7604
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229227
Homologene: 52105
Qrich1
Name: glutamine-rich 1
Synonyms: b2b2404Clo, 2610028H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69232
Homologene: 9803
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Zfp512
Name: zinc finger protein 512
Synonyms: 2500002M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269639
Homologene: 13026
Phka2
Name: phosphorylase kinase alpha 2
Synonyms: 6330505C01Rik, Phk, k
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 110094
HGNC: HGNC:8926
Homologene: 246
Orc3
Name: origin recognition complex, subunit 3
Synonyms: Orc3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50793
HGNC: HGNC:8489
Homologene: 8225
Pex1
Name: peroxisomal biogenesis factor 1
Synonyms: peroxisome biogenesis factor 1, 5430414H02Rik, E330005K07Rik, ZWS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71382
HGNC: HGNC:8850
Homologene: 27006
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Ube2n
Name: ubiquitin-conjugating enzyme E2N
Synonyms: UBC13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 93765
VEGA: 10
Homologene: 128406
Tdp2
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: Ttrap, D13Ertd656e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56196
Homologene: 9591
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: Supt6h, 5131400N11Rik, SPT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20926
Homologene: 40661
Snx29
Name: sorting nexin 29
Synonyms: 4933437K13Rik, LOC385605, Rundc2a, LOC381035, Gm11170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 74478
Homologene: 32706
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232798
Homologene: 13612
Rasgef1b
Name: RasGEF domain family, member 1B
Synonyms: Gpig4, 4732452O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320292
Homologene: 14860
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71169
VEGA: 12
Homologene: 41073
Atp2b4
Name: ATPase, Ca++ transporting, plasma membrane 4
Synonyms: PMCA4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381290
HGNC: HGNC:817
Homologene: 48034
Rfx8
Name: regulatory factor X 8
Synonyms: 4933400N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 619289
Homologene: 82436
Mlkl
Name: mixed lineage kinase domain-like
Synonyms: 9130019I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74568
Homologene: 77416
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: Mlsn1, LTRPC1, melastatin, 4732499L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69983
Homologene: 37424
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242627
Homologene: 135888
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: 6430526J12Rik, mdig, Megf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Cblif
Name: cobalamin binding intrinsic factor
Synonyms: Gif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14603
HGNC: HGNC:4268
Homologene: 3773
Ccdc54
Name: coiled-coil domain containing 54
Synonyms: 1700007N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 69339
VEGA: 16
Homologene: 49871
9330182L06Rik
Name: RIKEN cDNA 9330182L06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231014
Homologene: 27396
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241919
Homologene: 76320
Npr2
Name: natriuretic peptide receptor 2
Synonyms: guanylyl cyclase-B, cn, pwe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Pcnx
Name: pecanex homolog
Synonyms: 2900024E21Rik, 3526401J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 54604
VEGA: 12
Homologene: 40997
Nell2
Name: NEL-like 2
Synonyms: mel91, A330108N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 54003
VEGA: 15
HGNC: HGNC:7751
Homologene: 4488
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17837
Homologene: 136663
Sp100
Name: nuclear antigen Sp100
Synonyms: A430075G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20684
Homologene: 86761
Caskin2
Name: CASK-interacting protein 2
Synonyms: 1600028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 140721
Homologene: 32485
Adam9
Name: a disintegrin and metallopeptidase domain 9 (meltrin gamma)
Synonyms: MDC9, Mltng, MDC9, Mltng
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11502
HGNC: HGNC:216
Homologene: 20824
Abtb2
Name: ankyrin repeat and BTB (POZ) domain containing 2
Synonyms: BPOZ-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99382
Homologene: 15904
Trim47
Name: tripartite motif-containing 47
Synonyms: 2210023F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217333
Homologene: 14128
Aim2
Name: absent in melanoma 2
Synonyms: Ifi210, LOC383619
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 383619
HGNC: HGNC:357
Homologene: 83226
Ccl11
Name: chemokine (C-C motif) ligand 11
Synonyms: eotaxin, Scya11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20292
Homologene: 7929
4933417A18Rik
Name: RIKEN cDNA 4933417A18 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66761
Homologene: 23555
Gabrb3
Name: gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
Synonyms: Gabrb-3, beta3, A230092K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14402
HGNC: HGNC:4083
Homologene: 633
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Defb19
Name: defensin beta 19
Synonyms: Tdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 246700
Homologene: 17045
Vmn2r17
Name: vomeronasal 2, receptor 17
Synonyms: EG384221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 384221
Homologene: 104825
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74485
Homologene: 83646
Qrfpr
Name: pyroglutamylated RFamide peptide receptor
Synonyms: Gpr103, AQ27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229214
Homologene: 18865
Nek2
Name: NIMA (never in mitosis gene a)-related expressed kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18005
HGNC: HGNC:7745
Homologene: 74441
Mgat5
Name: mannoside acetylglucosaminyltransferase 5
Synonyms: 5330407H02Rik, 4930471A21Rik, beta1,6N-acetylglucosaminyltransferase V, GlcNAc-TV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 107895
HGNC: HGNC:7049
Homologene: 1808
Hecw1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Synonyms: E130207I19Rik, NEDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 94253
VEGA: 13
Homologene: 9004
Mrps26
Name: mitochondrial ribosomal protein S26
Synonyms: MRP-S13, Rpms13, GI008, MRP-S26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99045
Homologene: 12778
Atat1
Name: alpha tubulin acetyltransferase 1
Synonyms: 2610110G12Rik, 3110080J08Rik, 2610008K08Rik, 0610011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73242
Homologene: 15129
Poglut1
Name: protein O-glucosyltransferase 1
Synonyms: Rumi, Ktelc1, wsnp, 9630046K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224143
Homologene: 41353
Tedc2
Name: tubulin epsilon and delta complex 2
Synonyms: 1600002H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 72016
Homologene: 45943
Hao1
Name: hydroxyacid oxidase 1, liver
Synonyms: Hao-1, Gox1, GOX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15112
HGNC: HGNC:4809
Homologene: 6578
Lonrf2
Name: LON peptidase N-terminal domain and ring finger 2
Synonyms: 2900060P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381338
Homologene: 18871
Reep6
Name: receptor accessory protein 6
Synonyms: Dp1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70335
Homologene: 133833
Gm14685
Name: predicted gene 14685
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 574404
Homologene: 128534
Tff2
Name: trefoil factor 2 (spasmolytic protein 1)
Synonyms: SP, mSP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21785
Homologene: 3956
Ppargc1a
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Synonyms: Pgc-1alpha, PPAR Gamma Coactivator-1, Pgc-1alphaa, Pgc1, Pgco1, Gm11133, A830037N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19017
HGNC: HGNC:9237
Homologene: 7485
2300003K06Rik
Name: RIKEN cDNA 2300003K06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 100502865
4930589L23Rik
Name: RIKEN cDNA 4930589L23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75879
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 38,813,276 bp
  • A to G, chromosome 1 at 39,685,559 bp
  • T to C, chromosome 1 at 85,696,995 bp
  • A to G, chromosome 1 at 127,397,607 bp
  • T to C, chromosome 1 at 133,715,169 bp
  • T to A, chromosome 1 at 172,118,957 bp
  • T to C, chromosome 1 at 173,463,982 bp
  • T to C, chromosome 1 at 191,821,652 bp
  • A to T, chromosome 2 at 40,697,482 bp
  • T to C, chromosome 2 at 91,491,942 bp
  • A to G, chromosome 2 at 103,705,117 bp
  • C to A, chromosome 2 at 130,564,167 bp
  • C to T, chromosome 2 at 134,498,258 bp
  • A to G, chromosome 2 at 152,576,170 bp
  • A to T, chromosome 2 at 155,210,576 bp
  • G to T, chromosome 2 at 158,007,445 bp
  • A to G, chromosome 2 at 168,925,808 bp
  • A to G, chromosome 3 at 31,237,362 bp
  • T to C, chromosome 3 at 36,221,894 bp
  • A to G, chromosome 3 at 36,947,853 bp
  • G to A, chromosome 3 at 72,913,237 bp
  • A to T, chromosome 3 at 79,572,465 bp
  • T to C, chromosome 3 at 87,742,673 bp
  • A to T, chromosome 4 at 34,584,846 bp
  • A to T, chromosome 4 at 43,646,560 bp
  • T to A, chromosome 4 at 52,462,948 bp
  • A to G, chromosome 4 at 113,819,163 bp
  • A to G, chromosome 4 at 148,462,852 bp
  • T to A, chromosome 4 at 148,466,025 bp
  • A to G, chromosome 4 at 152,057,782 bp
  • T to C, chromosome 5 at 3,603,341 bp
  • C to A, chromosome 5 at 9,463,030 bp
  • T to A, chromosome 5 at 31,465,449 bp
  • T to C, chromosome 5 at 51,473,788 bp
  • T to C, chromosome 5 at 99,228,055 bp
  • T to C, chromosome 5 at 109,452,486 bp
  • A to G, chromosome 6 at 122,077,492 bp
  • G to T, chromosome 6 at 128,270,962 bp
  • T to G, chromosome 7 at 4,144,290 bp
  • G to A, chromosome 7 at 5,008,236 bp
  • G to A, chromosome 7 at 57,824,493 bp
  • A to G, chromosome 7 at 64,240,555 bp
  • A to C, chromosome 7 at 144,937,391 bp
  • A to T, chromosome 8 at 24,991,294 bp
  • A to C, chromosome 8 at 95,739,841 bp
  • A to G, chromosome 8 at 111,314,928 bp
  • T to C, chromosome 9 at 44,823,374 bp
  • C to T, chromosome 9 at 107,962,919 bp
  • T to A, chromosome 9 at 108,559,270 bp
  • T to C, chromosome 9 at 108,956,921 bp
  • T to A, chromosome 10 at 80,330,322 bp
  • A to G, chromosome 10 at 95,541,266 bp
  • T to A, chromosome 11 at 78,224,361 bp
  • A to G, chromosome 11 at 82,062,202 bp
  • A to T, chromosome 11 at 99,837,736 bp
  • T to C, chromosome 11 at 115,806,301 bp
  • T to C, chromosome 11 at 116,108,283 bp
  • A to T, chromosome 12 at 8,013,134 bp
  • A to G, chromosome 12 at 13,474,206 bp
  • A to G, chromosome 12 at 81,933,674 bp
  • T to A, chromosome 13 at 14,297,413 bp
  • T to G, chromosome 13 at 24,840,374 bp
  • T to A, chromosome 13 at 34,924,591 bp
  • T to C, chromosome 15 at 95,435,109 bp
  • A to G, chromosome 16 at 11,631,492 bp
  • T to C, chromosome 16 at 38,534,807 bp
  • T to A, chromosome 16 at 50,590,624 bp
  • T to A, chromosome 17 at 24,216,317 bp
  • C to A, chromosome 17 at 24,216,318 bp
  • C to T, chromosome 17 at 24,574,796 bp
  • T to C, chromosome 17 at 25,160,120 bp
  • T to C, chromosome 17 at 31,143,225 bp
  • T to A, chromosome 17 at 35,901,369 bp
  • C to G, chromosome 19 at 6,388,155 bp
  • G to A, chromosome 19 at 11,759,006 bp
  • G to T, chromosome X at 73,127,655 bp
  • T to A, chromosome X at 160,554,327 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2054 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040059-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.