Strain Name:
C57BL/6J-MtgxR2088Btlr/Mmmh
Stock Number:
040093-MU
Citation ID:
RRID:MMRRC_040093-MU
Other Names:
R2088 (G1), C57BL/6J-MtgxR2088Btlr
Major Collection:

Gene Information

Gli1
Name: GLI-Kruppel family member GLI1
Synonyms: Zfp5, Zfp-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14632
VEGA: 10
HGNC: HGNC:4317
Homologene: 3859
Arhgef10
Name: Rho guanine nucleotide exchange factor (GEF) 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234094
VEGA: 8
Homologene: 22827
Rbpms2
Name: RNA binding protein with multiple splicing 2
Synonyms: 2400008B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71973
VEGA: 9
Homologene: 49895
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72313
VEGA: 5
Homologene: 103956
Hap1
Name: huntingtin-associated protein 1
Synonyms: HAP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15114
VEGA: 11
HGNC: HGNC:4812
Homologene: 2935
Gpr1
Name: G protein-coupled receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241070
VEGA: 1
HGNC: HGNC:4463
Homologene: 21094
Znfx1
Name: zinc finger, NFX1-type containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98999
VEGA: 2
Homologene: 10877
Iqgap2
Name: IQ motif containing GTPase activating protein 2
Synonyms: 4933417J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 544963
VEGA: 13
HGNC: HGNC:6111
Homologene: 101543
Skp2
Name: S-phase kinase-associated protein 2 (p45)
Synonyms: FBXL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 27401
VEGA: 15
Homologene: 55942
Txnrd1
Name: thioredoxin reductase 1
Synonyms: TR, TR1, TR alpha, TrxR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 50493
VEGA: 10
Homologene: 55733
Eif2d
Name: eukaryotic translation initiation factor 2D
Synonyms: Lgtn, D1Ertd5e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16865
VEGA: 1
HGNC: HGNC:6583
Homologene: 38244
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 20191
VEGA: 13
Homologene: 37423
Trappc10
Name: trafficking protein particle complex 10
Synonyms: LOC380642, b2b2416Clo, b2b2613Clo, Tmem1, B230307C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216131
VEGA: 10
Homologene: 37751
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13131
VEGA: 4
HGNC: HGNC:2661
Homologene: 32084
Cntnap1
Name: contactin associated protein-like 1
Synonyms: paranodin, NCP1, Caspr, shm, p190, Nrxn4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 53321
VEGA: 11
HGNC: HGNC:8011
Homologene: 2693
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14426
VEGA: 10
HGNC: HGNC:4126
Homologene: 74511
Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms: Np95, ICBP90
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18140
VEGA: 17
Homologene: 7866
Rplp0
Name: ribosomal protein, large, P0
Synonyms: 36B4, Arbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11837
VEGA: 5
Homologene: 6517
Prune2
Name: prune homolog 2
Synonyms: A330102H22Rik, 6330414G02Rik, A230083H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Canx
Name: calnexin
Synonyms: CNX, 1110069N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12330
VEGA: 11
HGNC: HGNC:1473
Homologene: 1324
P4hb
Name: prolyl 4-hydroxylase, beta polypeptide
Synonyms: Thbp, PDI, protein disulfide isomerase, ERp59, Pdia1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18453
VEGA: 11
HGNC: HGNC:8548
Homologene: 55495
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, FLASH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 26885
VEGA: 4
HGNC: HGNC:1510
Homologene: 8066
Ndufa11
Name: NADH:ubiquinone oxidoreductase subunit A11
Synonyms: 11, 14.7kDa, 2010012C24Rik, B14.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 69875
VEGA: 17
Homologene: 17926
Mtmr4
Name: myotubularin related protein 4
Synonyms: ESTM44, FYVE zinc finger phosphatase, FYVE-DSP2, ZFYVE11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 170749
VEGA: 11
HGNC: HGNC:7452
Homologene: 3440
Limd2
Name: LIM domain containing 2
Synonyms: 0610025L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67803
VEGA: 11
Homologene: 12731
Krt14
Name: keratin 14
Synonyms: Krt-1.14, Cytokeratin 14, Krt1-14, K14, epidermolysis bullosa simplex, Dowling-Meara, Koebner
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16664
VEGA: 11
HGNC: HGNC:6416
Homologene: 110439
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229474
VEGA: 3
Homologene: 18920
Tatdn3
Name: TatD DNase domain containing 3
Synonyms: 1500010M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68972
VEGA: 1
Homologene: 45949
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E21Rik, 2310076E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76469
VEGA: 13
Homologene: 137367
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
VEGA: 16
HGNC: HGNC:7514
Homologene: 124469
RP24-528G7.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329178
VEGA: 1
Homologene: 122243
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
VEGA: 17
Homologene: 56696
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 229003
VEGA: 2
Homologene: 14118
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231915
VEGA: 5
Homologene: 4235
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232358
Homologene: 84037
Msto1
Name: misato 1, mitochondrial distribution and morphology regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229524
VEGA: 3
Homologene: 41228
Gatm
Name: glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Synonyms: 1810003P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67092
VEGA: 2
HGNC: HGNC:4175
Homologene: 1136
Rtp4
Name: receptor transporter protein 4
Synonyms: 5830458K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67775
VEGA: 16
Homologene: 56944
Olfr124
Name: olfactory receptor 124
Synonyms: GA_x6K02T2PSCP-2264806-2265753, MOR256-3, A3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 259064
VEGA: 17
Homologene: 74266
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D130016K21Rik, Usmg4, 9430063L05Rik, 4732458A06Rik, D3Bwg1078e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 83679
VEGA: 3
Homologene: 66961
Klra2
Name: killer cell lectin-like receptor, subfamily A, member 2
Synonyms: Ly49b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16633
VEGA: 6
Homologene: 133782
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 194357
VEGA: 6
Homologene: 77226
St6galnac1
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Synonyms: ST6GalNAc I, Siat7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20445
VEGA: 11
Homologene: 7937
Lipo4
Name: lipase, member O4
Synonyms: Gm6857
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 628236
Homologene: 103863
Simc1
Name: SUMO-interacting motifs containing 1
Synonyms: 4732471D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319719
VEGA: 13
Homologene: 131217
Rab12
Name: RAB12, member RAS oncogene family
Synonyms: 2900054P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19328
VEGA: 17
Homologene: 103879
Cbfa2t3
Name: CBFA2/RUNX1 translocation partner 3
Synonyms: ETO-2, Eto2, A630044F12Rik, MTGR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12398
VEGA: 8
HGNC: HGNC:1537
Homologene: 74543
Ano5
Name: anoctamin 5
Synonyms: Gdd1, Tmem16e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233246
Homologene: 100071
Slc46a1
Name: solute carrier family 46, member 1
Synonyms: heme carrier protein 1, PCFT, HCP1, 1110002C08Rik, D11Ertd18e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 52466
VEGA: 11
Homologene: 41693
Bmp2k
Name: BMP2 inducible kinase
Synonyms: BIKE, 4933417M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 140780
VEGA: 5
Homologene: 34134
Klhl33
Name: kelch-like 33
Synonyms: EG546611
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 546611
VEGA: 14
Homologene: 52385
Ankk1
Name: ankyrin repeat and kinase domain containing 1
Synonyms: 9930020N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244859
VEGA: 9
Homologene: 18258
Ctnna3
Name: catenin (cadherin associated protein), alpha 3
Synonyms: 4930429L08Rik, alphaT-catenin, Catna3, Vr22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216033
VEGA: 10
HGNC: HGNC:2511
Homologene: 56583
Sh2b2
Name: SH2B adaptor protein 2
Synonyms: Aps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 23921
VEGA: 5
Homologene: 10309
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227157
VEGA: 1
Homologene: 23296
Pde4c
Name: phosphodiesterase 4C, cAMP specific
Synonyms: dunce, E130301F19Rik, Dpde1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 110385
VEGA: 8
HGNC: HGNC:8782
Homologene: 20256
Mab21l2
Name: mab-21-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 23937
VEGA: 3
HGNC: HGNC:6758
Homologene: 7824
Tmem25
Name: transmembrane protein 25
Synonyms: 0610039J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71687
VEGA: 9
Homologene: 12403
Itga3
Name: integrin alpha 3
Synonyms: alpha3-integrin, VLA-3 alpha 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16400
VEGA: 11
HGNC: HGNC:6139
Homologene: 21129
Gsdmc3
Name: gasdermin C3
Synonyms: 9930109F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 270328
HGNC: HGNC:7151
Homologene: 69487
Rhbg
Name: Rhesus blood group-associated B glycoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 58176
VEGA: 3
Homologene: 9469
Orai2
Name: ORAI calcium release-activated calcium modulator 2
Synonyms: Tmem142b, A730041O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269717
VEGA: 5
Homologene: 32799
Vmn1r232
Name: vomeronasal 1 receptor 232
Synonyms: V1re4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171227
VEGA: 17
Homologene: 121611
Olfr1289
Name: olfactory receptor 1289
Synonyms: GA_x6K02T2Q125-72534883-72535821, MOR245-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258399
VEGA: 2
HGNC: HGNC:8301
Insyn1
Name: inhibitory synaptic factor 1
Synonyms: 6030419C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319477
VEGA: 9
Homologene: 18538
Fam71e1
Name: family with sequence similarity 71, member E1
Synonyms: 1700021P22Rik, 1700021N13Rik, 0610007G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75538
VEGA: 7
Homologene: 19259
Nat8b-ps
Name: N-acetyltransferase 8B, pseudogene
Synonyms: Nat8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 434057
BC107364
Name: cDNA sequence BC107364
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 329716
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 59,123,465 bp
  • A to T, chromosome 1 at 63,183,652 bp
  • T to A, chromosome 1 at 66,590,227 bp
  • T to C, chromosome 1 at 131,164,727 bp
  • A to G, chromosome 1 at 191,052,876 bp
  • G to T, chromosome 2 at 111,484,278 bp
  • A to G, chromosome 2 at 122,598,148 bp
  • A to G, chromosome 2 at 167,055,810 bp
  • C to T, chromosome 2 at 181,235,102 bp
  • T to C, chromosome 3 at 84,474,726 bp
  • T to G, chromosome 3 at 86,547,009 bp
  • T to C, chromosome 3 at 88,247,458 bp
  • C to T, chromosome 3 at 88,910,990 bp
  • T to C, chromosome 3 at 96,434,429 bp
  • T to C, chromosome 3 at 97,754,433 bp
  • T to C, chromosome 4 at 32,631,126 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • T to A, chromosome 5 at 73,065,461 bp
  • T to A, chromosome 5 at 97,038,552 bp
  • T to A, chromosome 5 at 115,562,503 bp
  • C to A, chromosome 5 at 136,150,756 bp
  • T to A, chromosome 5 at 136,232,114 bp
  • T to A, chromosome 5 at 149,209,750 bp
  • G to A, chromosome 6 at 40,884,967 bp
  • A to C, chromosome 6 at 85,932,940 bp
  • A to T, chromosome 6 at 123,335,836 bp
  • T to C, chromosome 6 at 131,242,826 bp
  • G to T, chromosome 7 at 44,496,905 bp
  • T to A, chromosome 7 at 51,587,706 bp
  • A to G, chromosome 8 at 14,983,898 bp
  • A to G, chromosome 8 at 70,749,356 bp
  • C to T, chromosome 8 at 122,637,986 bp
  • C to A, chromosome 9 at 44,796,086 bp
  • T to C, chromosome 9 at 49,421,965 bp
  • T to C, chromosome 9 at 58,499,005 bp
  • T to A, chromosome 9 at 65,630,839 bp
  • A to G, chromosome 10 at 64,873,207 bp
  • A to G, chromosome 10 at 78,196,334 bp
  • G to A, chromosome 10 at 82,883,910 bp
  • A to G, chromosome 10 at 99,109,184 bp
  • T to G, chromosome 10 at 127,331,500 bp
  • C to T, chromosome 11 at 50,310,390 bp
  • T to C, chromosome 11 at 78,468,645 bp
  • T to C, chromosome 11 at 87,610,967 bp
  • T to A, chromosome 11 at 95,052,494 bp
  • T to C, chromosome 11 at 100,204,123 bp
  • T to C, chromosome 11 at 100,356,002 bp
  • T to A, chromosome 11 at 101,182,547 bp
  • A to G, chromosome 11 at 106,158,742 bp
  • A to G, chromosome 11 at 116,769,107 bp
  • G to A, chromosome 11 at 120,562,257 bp
  • C to A, chromosome 13 at 11,662,229 bp
  • T to C, chromosome 13 at 54,541,534 bp
  • A to T, chromosome 13 at 93,092,812 bp
  • C to T, chromosome 13 at 95,891,663 bp
  • A to T, chromosome 14 at 50,892,773 bp
  • C to A, chromosome 15 at 9,113,698 bp
  • A to C, chromosome 15 at 63,860,214 bp
  • A to T, chromosome 16 at 23,613,213 bp
  • T to A, chromosome 16 at 32,756,409 bp
  • C to G, chromosome 16 at 38,347,180 bp
  • A to T, chromosome 17 at 20,913,737 bp
  • A to G, chromosome 17 at 37,805,795 bp
  • A to G, chromosome 17 at 46,526,649 bp
  • A to T, chromosome 17 at 56,318,089 bp
  • C to A, chromosome 17 at 56,717,922 bp
  • A to T, chromosome 17 at 66,497,457 bp
  • A to G, chromosome 19 at 17,119,745 bp
  • A to T, chromosome 19 at 33,500,069 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2088 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040093-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.