Strain Name:
C57BL/6J-MtgxR2098Btlr/Mmmh
Stock Number:
040102-MU
Citation ID:
RRID:MMRRC_040102-MU
Other Names:
R2098 (G1), C57BL/6J-MtgxR2098Btlr
Major Collection:

Gene Information

Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 104245
Homologene: 37901
Ctdspl2
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
Synonyms: D2Ertd485e, SCP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329506
Homologene: 32311
Skap2
Name: src family associated phosphoprotein 2
Synonyms: RA70, Saps, mSKAP55R, 2610021A10Rik, SKAP-HOM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54353
Homologene: 2919
Rad51c
Name: RAD51 paralog C
Synonyms: Rad51l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 114714
HGNC: HGNC:9820
Homologene: 14238
Mllt10
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
Synonyms: Af10, B130021D15Rik, D630001B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17354
Homologene: 20973
Thrap3
Name: thyroid hormone receptor associated protein 3
Synonyms: 9330151F09Rik, Trap150, B230333E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230753
Homologene: 31289
Psmd1
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Synonyms: P112, S1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70247
HGNC: HGNC:9554
Homologene: 2100
Srek1
Name: splicing regulatory glutamine/lysine-rich protein 1
Synonyms: SRrp508, SRrp86, Sfrs12, AL118220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218543
Homologene: 10581
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 1810014J18Rik, AD013, A330063D19Rik, 9030205D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109151
Homologene: 11844
Bend3
Name: BEN domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 331623
VEGA: 10
Homologene: 19511
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: p200RhoGAP, GC-GAP, PX-RICS, 3426406O18Rik, Grit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330914
Homologene: 8812
Marf1
Name: meiosis regulator and mRNA stability 1
Synonyms: 4921513D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 223989
VEGA: 16
Homologene: 40967
Cyth1
Name: cytohesin 1
Synonyms: CLM1, CTH-1, Pscd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19157
HGNC: HGNC:9501
Homologene: 31262
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74015
Homologene: 22869
Pcbp2
Name: poly(rC) binding protein 2
Synonyms: alphaCP-2, Hnrpx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18521
VEGA: 15
HGNC: HGNC:8648
Homologene: 74536
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: SPT6, 5131400N11Rik, Supt6h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20926
Homologene: 40661
Fam3d
Name: FAM3 metabolism regulating signaling molecule D
Synonyms: EF-7, 2310076N21Rik, Oit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18300
VEGA: 14
Homologene: 16354
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: polycystin-2, C030034P18Rik, TRPP2, PC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Cmip
Name: c-Maf inducing protein
Synonyms: 5830471E12Rik, 4933407C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74440
Homologene: 18869
Eps8l2
Name: EPS8-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 98845
Homologene: 69358
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, CED-5, Hch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Slc16a4
Name: solute carrier family 16 (monocarboxylic acid transporters), member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229699
Homologene: 74529
Myo6
Name: myosin VI
Synonyms: Tlc, Myo6rsv, rsv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Cfap206
Name: cilia and flagella associated protein 206
Synonyms: 1700003M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69329
Homologene: 18713
Ptchd3
Name: patched domain containing 3
Synonyms: 4933440L20Rik, 4930451E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74675
Homologene: 111041
V1rd19
Name: vomeronasal 1 receptor, D19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404287
Homologene: 104166
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: CaMK II, 2810011D23Rik, 8030469K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Cdhr2
Name: cadherin-related family member 2
Synonyms: LOC268663, Pcdh24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 268663
Homologene: 134510
Olfr684
Name: olfactory receptor 684
Synonyms: GA_x6K02T2PBJ9-7786441-7785503, MOR40-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244187
Homologene: 133596
Arhgef10l
Name: Rho guanine nucleotide exchange factor (GEF) 10-like
Synonyms: 2810441C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72754
Homologene: 10017
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, alpha(1B), Cav2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Nsun7
Name: NOL1/NOP2/Sun domain family, member 7
Synonyms: 4921525L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70918
Homologene: 11653
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319800
Homologene: 77136
Mrps2
Name: mitochondrial ribosomal protein S2
Synonyms: 1500019M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 118451
Homologene: 99837
Mmp1b
Name: matrix metallopeptidase 1b (interstitial collagenase)
Synonyms: Mcol-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83996
HGNC: HGNC:7155
Homologene: 130791
Gm10250
Name: predicted pseudogene 10250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 100039281
VEGA: 15
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226438
Homologene: 130054
Olfr1136
Name: olfactory receptor 1136
Synonyms: GA_x6K02T2Q125-49193051-49192119, MOR177-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258653
Homologene: 74193
Zfp267
Name: zinc finger protein 267
Synonyms: D3Ertd254e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241944
Homologene: 117700
Prl5a1
Name: prolactin family 5, subfamily a, member 1
Synonyms: 1600013P04Rik, PLP-L, D13Wsu14e, Prlpl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 28078
Homologene: 11378
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: SNS2, NaN, NaT, NSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
St8sia4
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Synonyms: ST8SiaIV, PST, PST-1, Siat8d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20452
Homologene: 4147
Olfr434
Name: olfactory receptor 434
Synonyms: GA_x6K02T2P3E9-4341246-4340281, MOR261-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258366
Homologene: 133700
Tas2r103
Name: taste receptor, type 2, member 103
Synonyms: TRB2, T2R3, mt2r63, mGR03, Tas2r3, Tas2r10, EG667992
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667992
Homologene: 130076
Slc7a15
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
Synonyms: 2010001P20Rik, Arpat, 9030221C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328059
Homologene: 77627
Olfr1206
Name: olfactory receptor 1206
Synonyms: GA_x6K02T2Q125-50339974-50340609, GA_x6K02T2Q125-50338497-50339264, MOR230-3, Olfr1207
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258896
Homologene: 81567
Spire1
Name: spire type actin nucleation factor 1
Synonyms: Spir-1, 6030430B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68166
VEGA: 18
Homologene: 35507
Gm9772
Name: predicted gene 9772
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100416807
VEGA: 17
Cd84
Name: CD84 antigen
Synonyms: CDw84, SLAMF5, A130013D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Sgpp1
Name: sphingosine-1-phosphate phosphatase 1
Synonyms: mSPP1, SPP1, SPP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 81535
VEGA: 12
Homologene: 101696
Gm2058
Name: predicted gene 2058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039133
Nudt16
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 16
Synonyms: 2810047L04Rik, 2900006H04Rik, 2310041H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75686
Homologene: 12617
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 86,082,101 bp
  • T to C, chromosome 1 at 95,653,528 bp
  • T to A, chromosome 1 at 135,978,305 bp
  • G to A, chromosome 1 at 171,885,581 bp
  • T to C, chromosome 2 at 18,162,653 bp
  • C to T, chromosome 2 at 24,650,546 bp
  • C to A, chromosome 2 at 28,468,315 bp
  • A to T, chromosome 2 at 87,693,729 bp
  • A to T, chromosome 2 at 88,864,871 bp
  • T to C, chromosome 2 at 121,977,324 bp
  • T to A, chromosome 3 at 36,166,140 bp
  • C to A, chromosome 3 at 107,300,847 bp
  • G to A, chromosome 3 at 126,780,442 bp
  • G to A, chromosome 4 at 34,719,053 bp
  • A to G, chromosome 4 at 126,180,030 bp
  • G to A, chromosome 4 at 137,520,109 bp
  • G to C, chromosome 4 at 140,579,432 bp
  • A to G, chromosome 5 at 66,283,712 bp
  • C to T, chromosome 5 at 104,478,902 bp
  • G to A, chromosome 6 at 43,217,503 bp
  • A to G, chromosome 6 at 51,860,107 bp
  • T to C, chromosome 6 at 133,036,597 bp
  • C to T, chromosome 7 at 24,003,735 bp
  • G to A, chromosome 7 at 39,589,186 bp
  • T to C, chromosome 7 at 49,945,567 bp
  • A to G, chromosome 7 at 105,157,271 bp
  • G to A, chromosome 7 at 141,355,792 bp
  • C to T, chromosome 8 at 71,709,981 bp
  • C to T, chromosome 8 at 91,033,987 bp
  • A to G, chromosome 8 at 117,447,454 bp
  • G to A, chromosome 9 at 7,386,984 bp
  • C to A, chromosome 9 at 32,259,911 bp
  • T to C, chromosome 9 at 80,281,526 bp
  • T to C, chromosome 9 at 105,131,287 bp
  • A to T, chromosome 9 at 119,792,494 bp
  • T to C, chromosome 10 at 43,510,504 bp
  • A to T, chromosome 11 at 34,266,279 bp
  • A to G, chromosome 11 at 34,719,005 bp
  • C to T, chromosome 11 at 59,069,991 bp
  • A to G, chromosome 11 at 78,213,261 bp
  • A to T, chromosome 11 at 87,402,763 bp
  • T to C, chromosome 11 at 110,036,579 bp
  • T to A, chromosome 11 at 118,193,653 bp
  • T to C, chromosome 11 at 121,842,479 bp
  • G to T, chromosome 12 at 8,535,668 bp
  • T to G, chromosome 12 at 75,716,510 bp
  • T to C, chromosome 13 at 28,145,505 bp
  • A to G, chromosome 13 at 54,715,644 bp
  • C to T, chromosome 13 at 100,245,195 bp
  • G to A, chromosome 13 at 103,744,855 bp
  • T to C, chromosome 14 at 8,361,479 bp
  • A to G, chromosome 15 at 5,120,814 bp
  • T to A, chromosome 15 at 102,498,481 bp
  • T to C, chromosome 16 at 14,114,200 bp
  • T to C, chromosome 17 at 22,006,637 bp
  • A to G, chromosome 18 at 67,503,466 bp
  • G to T, chromosome 19 at 5,708,658 bp
  • G to A, chromosome 19 at 8,400,811 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2098 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040102-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.