Strain Name:
C57BL/6J-MtgxR2107Btlr/Mmmh
Stock Number:
040111-MU
Citation ID:
RRID:MMRRC_040111-MU
Other Names:
R2107 (G1), C57BL/6J-MtgxR2107Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: E330008K23Rik, HALR, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Npy2r
Name: neuropeptide Y receptor Y2
Synonyms: NPY-Y2 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18167
HGNC: HGNC:7957
Homologene: 701
Plin3
Name: perilipin 3
Synonyms: 1300012C15Rik, Tip47, M6prbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66905
VEGA: 17
Homologene: 4247
Ccdc88c
Name: coiled-coil domain containing 88C
Synonyms: Daple, 0610010D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68339
VEGA: 12
Homologene: 18903
Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd1, Edd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Pias2
Name: protein inhibitor of activated STAT 2
Synonyms: Dib, 6330408K17Rik, ARIP3, PIASxbeta, PIASxalpha, PIASxb, Miz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17344
VEGA: 18
Homologene: 20979
Pck1
Name: phosphoenolpyruvate carboxykinase 1, cytosolic
Synonyms: Pck-1, PEPCK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18534
HGNC: HGNC:8724
Homologene: 1944
Rgs12
Name: regulator of G-protein signaling 12
Synonyms: 4632412M04Rik, 1200016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71729
HGNC: HGNC:9994
Homologene: 2195
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 64652
Homologene: 136161
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: med, seal, motor end-plate disease, nmf2, ataxia 3, mnd2, mnd-2, C630029C19Rik, nmf58, NaCh6, Nav1.6, nmf335, NMF335, nur14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20273
Homologene: 7927
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: 9030624J02Rik, Vsp35l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: 2610529N02Rik, 2610510H01Rik, Td60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 108911
Homologene: 10282
Sp1
Name: trans-acting transcription factor 1
Synonyms: Sp1-1, 1110003E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20683
Homologene: 8276
Kpna3
Name: karyopherin (importin) alpha 3
Synonyms: IPOA4, importin alpha 4, importin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16648
VEGA: 14
HGNC: HGNC:6396
Homologene: 20520
Tasor
Name: transcription activation suppressor
Synonyms: 4933409E02Rik, D14Abb1e, MommeD6, Fam208a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Csad
Name: cysteine sulfinic acid decarboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 246277
VEGA: 15
Homologene: 41086
Bcas3
Name: breast carcinoma amplified sequence 3
Synonyms: K20D4, 1500019F07Rik, 2610028P08Rik, rudhira
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192197
Homologene: 9778
Dyrk1a
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
Synonyms: Mnbh, Dyrk, D16Ertd493e, 2310043O08Rik, D16Ertd272e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13548
HGNC: HGNC:3091
Homologene: 55576
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Zfp26
Name: zinc finger protein 26
Synonyms: mkr-3, Zfp-26, 5033428C05Rik, Zfp70, KRAB15, Zfp81-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22688
Homologene: 52318
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54194
VEGA: 17
Homologene: 8658
Ubqln1
Name: ubiquilin 1
Synonyms: XDRP1, Dsk2, DA41, Plic-1, 1110046H03Rik, 1810030E05Rik, D13Ertd372e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56085
VEGA: 13
Homologene: 137258
Fabp3
Name: fatty acid binding protein 3, muscle and heart
Synonyms: H-FABP, Fabph-4, Fabph-1, Fabph4, Fabph1, Mdgi, Fabp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14077
HGNC: HGNC:3557
Homologene: 68379
Smap1
Name: small ArfGAP 1
Synonyms: 4921514B13Rik, 1700056O10Rik, 4921525H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98366
Homologene: 134676
Tbc1d1
Name: TBC1 domain family, member 1
Synonyms: 1110062G02Rik, Nob1, Nobq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57915
Homologene: 56856
Fan1
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: 6030441H18Rik, Mtmr15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330554
Homologene: 45598
Ace2
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Synonyms: 2010305L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 70008
Homologene: 41448
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22325
Homologene: 2530
Crmp1
Name: collapsin response mediator protein 1
Synonyms: Ulip3, DRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12933
HGNC: HGNC:2365
Homologene: 20347
Cdc20
Name: cell division cycle 20
Synonyms: p55CDC, 2310042N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107995
HGNC: HGNC:1723
Homologene: 37459
Golm1
Name: golgi membrane protein 1
Synonyms: D030064E01Rik, PSEC0257, GP73, 2310001L02Rik, Golph2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105348
VEGA: 13
Homologene: 12346
Rnf6
Name: ring finger protein (C3H2C3 type) 6
Synonyms: 5730419H05Rik, 1200013I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74132
Homologene: 14036
Cblb
Name: Casitas B-lineage lymphoma b
Synonyms: Cbl-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208650
VEGA: 16
HGNC: HGNC:1542
Homologene: 15856
Trim37
Name: tripartite motif-containing 37
Synonyms: MUL, TEF3, 2810004E07Rik, 1110032A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68729
HGNC: HGNC:7523
Homologene: 9084
Nav1
Name: neuron navigator 1
Synonyms: POMFIL3, 9930003A20Rik, C230080M11Rik, unc53H1, steerin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215690
Homologene: 10719
Plagl1
Name: pleiomorphic adenoma gene-like 1
Synonyms: Zac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22634
HGNC: HGNC:9046
Homologene: 31401
Myo15
Name: myosin XV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17910
HGNC: HGNC:7594
Homologene: 56504
Ipcef1
Name: interaction protein for cytohesin exchange factors 1
Synonyms: A130090K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320495
Homologene: 32271
Chia1
Name: chitinase, acidic 1
Synonyms: AMCase, YNL, 2200003E03Rik, Chia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Slco1a6
Name: solute carrier organic anion transporter family, member 1a6
Synonyms: organic anion-transporting polypeptide, Oatp-5, 4930422F19Rik, Slc21a13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28254
Homologene: 23416
Olfr59
Name: olfactory receptor 59
Synonyms: IH3, MOR133-3P, GA_x6K02T2P1NL-4434429-4435400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18359
Homologene: 73924
Lrguk
Name: leucine-rich repeats and guanylate kinase domain containing
Synonyms: 4921528H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74354
Homologene: 34923
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: RIP3, p116Rip, p116 Rho interacting protein, Rhoip3, Gm34094
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26936
Homologene: 9034
Unc13a
Name: unc-13 homolog A
Synonyms: Munc13-1, 2410078G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382018
Homologene: 11279
Lrrc19
Name: leucine rich repeat containing 19
Synonyms: 9130022A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100061
Homologene: 36410
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233328
Homologene: 23464
Mmp1b
Name: matrix metallopeptidase 1b (interstitial collagenase)
Synonyms: Mcol-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83996
HGNC: HGNC:7155
Homologene: 130791
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Cgrrf1
Name: cell growth regulator with ring finger domain 1
Synonyms: 1110038G02Rik, CGR19, 1810009H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68755
Homologene: 4789
Rpusd3
Name: RNA pseudouridylate synthase domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101122
Homologene: 18342
Usp43
Name: ubiquitin specific peptidase 43
Synonyms: C630032K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216835
Homologene: 129879
Krt90
Name: keratin 90
Synonyms: 4732456N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239673
Homologene: 72272
Ogg1
Name: 8-oxoguanine DNA-glycosylase 1
Synonyms: Mmh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18294
HGNC: HGNC:8125
Homologene: 1909
Lamc2
Name: laminin, gamma 2
Synonyms: nicein, 100kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16782
HGNC: HGNC:6493
Homologene: 4062
Olfr350
Name: olfactory receptor 350
Synonyms: GA_x6K02T2NLDC-33544602-33545540, MOR136-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258620
HGNC: HGNC:8211
Homologene: 64897
Pde11a
Name: phosphodiesterase 11A
Synonyms: A630086N24Rik, 6330414F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241489
HGNC: HGNC:8773
Homologene: 56763
Neu1
Name: neuraminidase 1
Synonyms: sialidase 1, lysosomal sialidase, G9, Bat-7, Map-2, Apl, Neu-1, Aglp, Bat7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18010
HGNC: HGNC:7758
Homologene: 375
Slc23a1
Name: solute carrier family 23 (nucleobase transporters), member 1
Synonyms: YSPL3, SVCT1, D18Ucla2, Slc23a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 20522
Homologene: 40769
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Slc34a3
Name: solute carrier family 34 (sodium phosphate), member 3
Synonyms: NPTIIc, Npt2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 142681
Homologene: 15444
Pqlc3
Name: PQ loop repeat containing
Synonyms: E030024M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217430
Homologene: 16454
Gnal
Name: guanine nucleotide binding protein, alpha stimulating, olfactory type
Synonyms: G alpha 10, Golf, Gna10, 9630020G10Rik, 2610011C15Rik, Galphaolf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14680
VEGA: 18
HGNC: HGNC:4388
Homologene: 68222
Lmtk3
Name: lemur tyrosine kinase 3
Synonyms: Aatyk3, AATYK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381983
Homologene: 79449
Tjp3
Name: tight junction protein 3
Synonyms: ZO-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27375
VEGA: 10
Homologene: 8458
Olfr818
Name: olfactory receptor 818
Synonyms: GA_x6K02T2PULF-11624146-11623190, MOR110-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258773
Homologene: 74100
Acp2
Name: acid phosphatase 2, lysosomal
Synonyms: Acp-2, LAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11432
HGNC: HGNC:123
Homologene: 1217
Cplx4
Name: complexin 4
Synonyms: A930004D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225644
VEGA: 18
Homologene: 17150
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66971
Homologene: 9502
Nedd9
Name: neural precursor cell expressed, developmentally down-regulated gene 9
Synonyms: E230025G09Rik, CasL, HEF1, Cas-L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18003
VEGA: 13
HGNC: HGNC:7733
Homologene: 4669
Tff2
Name: trefoil factor 2 (spasmolytic protein 1)
Synonyms: mSP, SP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21785
Homologene: 3956
1700001O22Rik
Name: RIKEN cDNA 1700001O22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 73598
Homologene: 18859
Samd14
Name: sterile alpha motif domain containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217125
Homologene: 17130
Cmtm8
Name: CKLF-like MARVEL transmembrane domain containing 8
Synonyms: 2700018N07Rik, Cklfsf8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70031
VEGA: 9
Homologene: 12345
Hint3
Name: histidine triad nucleotide binding protein 3
Synonyms: 0610010I17Rik, HINT4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66847
Homologene: 12046
Gm9611
Name: predicted gene 9611
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108168189
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 23,848,454 bp
  • C to T, chromosome 1 at 135,449,004 bp
  • A to G, chromosome 1 at 153,154,386 bp
  • A to T, chromosome 2 at 25,230,987 bp
  • T to C, chromosome 2 at 27,267,303 bp
  • A to T, chromosome 2 at 30,795,732 bp
  • C to A, chromosome 2 at 36,850,343 bp
  • A to G, chromosome 2 at 76,337,922 bp
  • G to A, chromosome 2 at 91,203,595 bp
  • C to T, chromosome 2 at 154,353,246 bp
  • G to C, chromosome 2 at 173,154,068 bp
  • A to T, chromosome 3 at 82,541,129 bp
  • T to A, chromosome 3 at 106,128,840 bp
  • A to T, chromosome 4 at 34,808,593 bp
  • T to A, chromosome 4 at 94,639,294 bp
  • T to C, chromosome 4 at 118,433,513 bp
  • C to T, chromosome 4 at 130,312,387 bp
  • A to G, chromosome 4 at 140,721,185 bp
  • T to C, chromosome 5 at 25,309,824 bp
  • A to G, chromosome 5 at 34,966,735 bp
  • G to T, chromosome 5 at 37,242,494 bp
  • T to G, chromosome 5 at 64,284,705 bp
  • G to A, chromosome 5 at 146,211,281 bp
  • T to C, chromosome 6 at 34,062,361 bp
  • C to A, chromosome 6 at 113,329,293 bp
  • G to T, chromosome 6 at 113,415,562 bp
  • C to A, chromosome 6 at 121,654,612 bp
  • A to T, chromosome 6 at 142,112,854 bp
  • G to T, chromosome 7 at 45,793,969 bp
  • T to G, chromosome 7 at 64,366,788 bp
  • C to A, chromosome 7 at 66,279,282 bp
  • T to C, chromosome 7 at 118,794,539 bp
  • T to C, chromosome 8 at 71,656,251 bp
  • A to G, chromosome 9 at 7,369,310 bp
  • A to T, chromosome 9 at 20,442,237 bp
  • A to T, chromosome 9 at 114,796,108 bp
  • A to G, chromosome 10 at 6,890,501 bp
  • C to A, chromosome 10 at 12,436,364 bp
  • A to C, chromosome 10 at 13,128,647 bp
  • A to T, chromosome 10 at 30,618,256 bp
  • T to C, chromosome 10 at 81,280,544 bp
  • A to G, chromosome 10 at 129,945,712 bp
  • A to G, chromosome 11 at 59,769,891 bp
  • T to C, chromosome 11 at 60,491,810 bp
  • GC to G, chromosome 11 at 67,855,740 bp
  • T to C, chromosome 11 at 74,289,390 bp
  • G to A, chromosome 11 at 85,457,878 bp
  • G to A, chromosome 11 at 87,159,825 bp
  • T to C, chromosome 11 at 87,796,075 bp
  • T to G, chromosome 11 at 95,021,377 bp
  • A to G, chromosome 12 at 16,995,599 bp
  • G to T, chromosome 12 at 100,921,549 bp
  • A to G, chromosome 12 at 101,771,269 bp
  • A to T, chromosome 13 at 41,338,979 bp
  • A to G, chromosome 13 at 58,180,919 bp
  • T to C, chromosome 13 at 59,642,232 bp
  • T to A, chromosome 14 at 27,461,787 bp
  • C to T, chromosome 14 at 31,172,140 bp
  • A to T, chromosome 14 at 42,294,654 bp
  • T to A, chromosome 14 at 46,853,376 bp
  • T to C, chromosome 14 at 61,370,484 bp
  • T to A, chromosome 15 at 34,423,759 bp
  • A to G, chromosome 15 at 37,989,302 bp
  • A to T, chromosome 15 at 101,018,363 bp
  • A to G, chromosome 15 at 101,562,629 bp
  • G to C, chromosome 15 at 102,179,034 bp
  • A to G, chromosome 15 at 102,409,678 bp
  • T to A, chromosome 16 at 52,152,716 bp
  • C to T, chromosome 16 at 94,686,527 bp
  • T to C, chromosome 17 at 31,142,282 bp
  • C to T, chromosome 17 at 32,332,483 bp
  • G to A, chromosome 17 at 34,934,398 bp
  • A to T, chromosome 17 at 56,284,391 bp
  • T to A, chromosome 18 at 35,625,826 bp
  • A to G, chromosome 18 at 65,956,893 bp
  • T to A, chromosome 18 at 67,213,578 bp
  • T to C, chromosome 18 at 77,097,471 bp
  • A to G, chromosome X at 164,140,732 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2107 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040111-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.