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Strain Name:
C57BL/6J-MtgxR2163Btlr/Mmmh
Stock Number:
040166-MU
Citation ID:
RRID:MMRRC_040166-MU
Other Names:
R2163 (G1), C57BL/6J-MtgxR2163Btlr
Major Collection:

Strain Information

Cdh1
Name: cadherin 1
Synonyms: E-cadherin, Ecad, UM, uvomorulin, L-CAM, E-cad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Ubxn2a
Name: UBX domain protein 2A
Synonyms: 6330407P03Rik, Ubxd4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217379
Homologene: 17076
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Nsf
Name: N-ethylmaleimide sensitive fusion protein
Synonyms: SKD2, N-ethylmaleimide sensitive factor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18195
HGNC: HGNC:8016
Homologene: 4502
Zfr
Name: zinc finger RNA binding protein
Synonyms: C920030H05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22763
Homologene: 8009
Rpap3
Name: RNA polymerase II associated protein 3
Synonyms: 2310042P20Rik, D15Ertd682e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71919
VEGA: 15
Homologene: 11613
Sltm
Name: SAFB-like, transcription modulator
Synonyms: 5730455C01Rik, 9130215G10Rik, 5730555F13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66660
VEGA: 9
Homologene: 11696
Fh1
Name: fumarate hydratase 1
Synonyms: fumarase
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14194
HGNC: HGNC:3700
Homologene: 115
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67772
Homologene: 72405
Alkal1
Name: ALK and LTK ligand 1
Synonyms: EG620393, Fam150a, Augmentor beta, Augbeta
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 620393
Homologene: 82437
Arhgap17
Name: Rho GTPase activating protein 17
Synonyms: WBP15, Nadrin, Rich1, 5730403H17Rik, Nadrin2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70497
Homologene: 9984
Hspd1
Name: heat shock protein 1 (chaperonin)
Synonyms: Hsp60
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15510
HGNC: HGNC:5261
Homologene: 1626
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: RING4, PSF-1, MTP1, Tap-1, Ham-1, Ham1, Abcb2, TAP
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
Eps15
Name: epidermal growth factor receptor pathway substrate 15
Synonyms: 2410112D09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13858
HGNC: HGNC:3419
Homologene: 128359
Pdia4
Name: protein disulfide isomerase associated 4
Synonyms: ERp72, Erp72, Cai, U48620
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12304
Homologene: 21020
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66686
Homologene: 12010
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Eif5b
Name: eukaryotic translation initiation factor 5B
Synonyms: IF2, A030003E17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226982
Homologene: 134613
Ppp4r2
Name: protein phosphatase 4, regulatory subunit 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232314
Homologene: 17953
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 54403
Homologene: 55776
Ppara
Name: peroxisome proliferator activated receptor alpha
Synonyms: Nr1c1, PPAR-alpha, PPARalpha, Ppar, 4933429D07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19013
HGNC: HGNC:9232
Homologene: 21047
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Nlrp4a
Name: NLR family, pyrin domain containing 4A
Synonyms: Nalp-eta, E330028A19Rik, Nalp4a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243880
Homologene: 79696
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Fcer1a
Name: Fc receptor, IgE, high affinity I, alpha polypeptide
Synonyms: Fce1a, Fcr-5, FcERI
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14125
HGNC: HGNC:3609
Homologene: 1516
Katnal1
Name: katanin p60 subunit A-like 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231912
Homologene: 12942
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20272
Homologene: 55706
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Schnurri-2, Shn-2, Gm20114
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Sec14l1
Name: SEC14-like lipid binding 1
Synonyms: 1200017E04Rik, 2810012L19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74136
Homologene: 37719
Cyp2c70
Name: cytochrome P450, family 2, subfamily c, polypeptide 70
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226105
Homologene: 120027
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: b2b012Clo, Jbts17, Hug, 2410089E03Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73692
Homologene: 11315
Usp40
Name: ubiquitin specific peptidase 40
Synonyms: B230215L03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227334
Homologene: 32400
Slco1a8
Name: solute carrier organic anion transporter family, member 1a8
Synonyms: Gm6614
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 625716
Homologene: 87075
Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Synonyms: p16, Cyp2b, phenobarbitol inducible, type b, Cyp2b20
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13088
HGNC: HGNC:2615
Homologene: 73894
Wdpcp
Name: WD repeat containing planar cell polarity effector
Synonyms: homoloc-13, AV249152
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216560
Homologene: 9299
Adamts3
Name: ADAM metallopeptidase with thrombospondin type 1 motif 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Gm10047
Name: predicted gene 10047
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Nrp1
Name: neuropilin 1
Synonyms: Neuropilin-1, NP-1, NPN-1, Npn1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18186
HGNC: HGNC:8004
Homologene: 2876
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Adamts2
Name: ADAM metallopeptidase with thrombospondin type 1 motif 2
Synonyms: ADAM-TS2, hPCPNI, a disintegrin and metalloproteinase with thrombospondin repeats, procollagen N-proteinase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Chl1
Name: cell adhesion molecule L1-like
Synonyms: CALL, A530023M13Rik, close homolog of L1, LICAM2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12661
HGNC: HGNC:1939
Homologene: 21314
Vmn1r170
Name: vomeronasal 1 receptor 170
Synonyms: Gm5999
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546944
Homologene: 128341
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Slco1c1
Name: solute carrier organic anion transporter family, member 1c1
Synonyms: OATP-F, Slc21a14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58807
Homologene: 23008
Nell2
Name: NEL-like 2
Synonyms: mel91, A330108N19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54003
VEGA: 15
HGNC: HGNC:7751
Homologene: 4488
Tbc1d16
Name: TBC1 domain family, member 16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207592
Homologene: 10380
Gadl1
Name: glutamate decarboxylase-like 1
Synonyms: 1110027M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73748
Homologene: 45812
Sanbr
Name: SANT and BTB domain regulator of CSR
Synonyms: 0610010F05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71675
Homologene: 19038
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cchl2a, Cacna2, Ca(v)alpha2delta1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Axdnd1
Name: axonemal dynein light chain domain containing 1
Synonyms: LOC381304, 9430070O13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77352
Homologene: 52328
CAAA01221083.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Spam1
Name: sperm adhesion molecule 1
Synonyms: Ph-20
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20690
Homologene: 7547
Scn11a
Name: sodium channel, voltage-gated, type XI, alpha
Synonyms: SNS2, NaN, NaT, NSS2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24046
VEGA: 9
Homologene: 8041
Nfkbiz
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
Synonyms: Mail
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 80859
Homologene: 12734
Foxc1
Name: forkhead box C1
Synonyms: frkhda, fkh1, fkh-1, FREAC3, Mf1, Fkh1, Mf4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17300
HGNC: HGNC:3800
Homologene: 20373
Carf
Name: calcium response factor
Synonyms: Als2cr8
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241066
Homologene: 11689
Baiap2l2
Name: BAI1-associated protein 2-like 2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 207495
Homologene: 11811
Pinlyp
Name: phospholipase A2 inhibitor and LY6/PLAUR domain containing
Synonyms: 2310033E01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 641361
Homologene: 53159
Trdn
Name: triadin
Synonyms: 2310045H21Rik, triadin-3, triadin-2, triadin-1, triadin 3, triadin 2, triadin 1, EG432451
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 76757
VEGA: 10
Homologene: 38137
4930578I07Rik
Name: RIKEN cDNA 4930578I07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
Synonyms: GA_x6K02T2NLDC-33902472-33903401, MOR138-5P, MOR138-6, Olfr366
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 236509
Homologene: 114744
Il1r1
Name: interleukin 1 receptor, type I
Synonyms: IL-1 receptor alpha chain, CD121a, Il1r-1, IL-iR, IL-1R1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16177
HGNC: HGNC:5993
Homologene: 677
Tex47
Name: testis expressed 47
Synonyms: 4921511H03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70920
Homologene: 41723
Acp4
Name: acid phosphatase 4
Synonyms: EG546967, Acpt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100503991
Homologene: 57200
AC125117.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Vmn1r175
Name: vomeronasal 1 receptor 175
Synonyms: Gm6299
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 622222
Homologene: 128341
Rsph14
Name: radial spoke head homolog 14 (Chlamydomonas)
Synonyms: 4933431K05Rik, Rtdr1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71236
Homologene: 49382
Syt15
Name: synaptotagmin XV
Synonyms: CHR10SYT, sytXV, E230025K04Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319508
Homologene: 12901
Catsper2
Name: cation channel, sperm associated 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 212670
Homologene: 77423
Or5w10
Name: olfactory receptor family 5 subfamily W member 10
Synonyms: GA_x6K02T2Q125-49048592-49047657, MOR176-3, Olfr1128
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258346
Chtop
Name: chromatin target of PRMT1
Synonyms: friend of Prmt1, Fop, 2500003M10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66511
Homologene: 137362
Efhd1
Name: EF hand domain containing 1
Synonyms: PP3051, 4931430I01Rik, mitocalcin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98363
Homologene: 41618
Hoxd13
Name: homeobox D13
Synonyms: Hox-4.8, spdh
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15433
HGNC: HGNC:5136
Homologene: 20147
Nenf
Name: neuron derived neurotrophic factor
Synonyms: 1110060M21Rik, neudesin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66208
Homologene: 8352
Fbxo3
Name: F-box protein 3
Synonyms: Fba, 1700026K02Rik, 1200002G09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57443
Homologene: 8133
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 6,389,512 bp
  • A to T, chromosome 1 at 38,048,794 bp
  • A to G, chromosome 1 at 40,294,863 bp
  • A to G, chromosome 1 at 55,078,538 bp
  • T to C, chromosome 1 at 60,147,486 bp
  • A to T, chromosome 1 at 87,289,473 bp
  • T to C, chromosome 1 at 87,995,858 bp
  • A to C, chromosome 1 at 156,392,003 bp
  • A to G, chromosome 1 at 158,502,150 bp
  • A to G, chromosome 1 at 173,222,697 bp
  • A to G, chromosome 1 at 175,614,840 bp
  • T to A, chromosome 1 at 191,309,935 bp
  • A to G, chromosome 2 at 37,220,077 bp
  • T to C, chromosome 2 at 66,675,956 bp
  • T to A, chromosome 2 at 74,669,069 bp
  • A to T, chromosome 2 at 76,811,243 bp
  • T to C, chromosome 2 at 76,812,501 bp
  • A to G, chromosome 2 at 87,544,894 bp
  • C to A, chromosome 2 at 104,054,985 bp
  • T to C, chromosome 2 at 121,400,175 bp
  • A to T, chromosome 3 at 90,502,211 bp
  • T to A, chromosome 4 at 109,370,669 bp
  • T to C, chromosome 5 at 7,305,022 bp
  • C to T, chromosome 5 at 16,362,319 bp
  • T to C, chromosome 5 at 35,802,353 bp
  • T to A, chromosome 5 at 44,014,163 bp
  • A to G, chromosome 5 at 89,214,576 bp
  • A to G, chromosome 5 at 89,708,718 bp
  • T to C, chromosome 5 at 104,455,677 bp
  • T to A, chromosome 5 at 148,888,936 bp
  • A to G, chromosome 6 at 24,796,847 bp
  • C to T, chromosome 6 at 47,798,407 bp
  • A to T, chromosome 6 at 73,089,746 bp
  • C to A, chromosome 6 at 100,865,086 bp
  • A to T, chromosome 6 at 103,711,231 bp
  • T to A, chromosome 6 at 141,559,752 bp
  • G to A, chromosome 6 at 141,980,938 bp
  • T to C, chromosome 7 at 23,607,037 bp
  • A to G, chromosome 7 at 23,808,927 bp
  • T to A, chromosome 7 at 24,541,801 bp
  • A to T, chromosome 7 at 25,925,385 bp
  • T to C, chromosome 7 at 26,453,397 bp
  • T to C, chromosome 7 at 44,255,976 bp
  • A to G, chromosome 7 at 123,283,833 bp
  • CGTG to CGTGTG, chromosome 7 at 141,699,185 bp
  • A to G, chromosome 8 at 106,649,081 bp
  • T to A, chromosome 8 at 128,497,871 bp
  • T to A, chromosome 9 at 70,591,682 bp
  • T to A, chromosome 9 at 115,949,558 bp
  • T to G, chromosome 9 at 119,755,025 bp
  • T to A, chromosome 10 at 14,128,226 bp
  • T to C, chromosome 10 at 33,363,964 bp
  • A to G, chromosome 10 at 52,286,356 bp
  • T to A, chromosome 10 at 74,957,779 bp
  • T to C, chromosome 10 at 88,540,942 bp
  • G to T, chromosome 11 at 21,885,015 bp
  • T to C, chromosome 11 at 23,576,826 bp
  • T to A, chromosome 11 at 50,788,805 bp
  • G to C, chromosome 11 at 103,863,333 bp
  • T to A, chromosome 11 at 117,143,282 bp
  • G to C, chromosome 11 at 119,155,078 bp
  • A to T, chromosome 12 at 4,885,757 bp
  • C to A, chromosome 13 at 31,808,603 bp
  • A to G, chromosome 14 at 34,226,116 bp
  • T to C, chromosome 14 at 51,317,766 bp
  • T to A, chromosome 14 at 52,198,818 bp
  • C to A, chromosome 14 at 66,938,548 bp
  • A to G, chromosome 14 at 103,169,855 bp
  • T to A, chromosome 15 at 8,203,251 bp
  • T to C, chromosome 15 at 8,336,919 bp
  • T to A, chromosome 15 at 12,162,223 bp
  • T to A, chromosome 15 at 55,444,645 bp
  • T to C, chromosome 15 at 79,259,195 bp
  • A to G, chromosome 15 at 85,801,046 bp
  • G to T, chromosome 15 at 95,429,978 bp
  • T to A, chromosome 15 at 97,680,348 bp
  • T to C, chromosome 16 at 55,818,218 bp
  • A to T, chromosome 17 at 34,189,473 bp
  • G to A, chromosome 19 at 40,160,719 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2163 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040166-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.