Strain Name:
C57BL/6J-MtgxR2165Btlr/Mmmh
Stock Number:
040168-MU
Citation ID:
RRID:MMRRC_040168-MU
Other Names:
R2165 (G1), C57BL/6J-MtgxR2165Btlr
Major Collection:

Gene Information

Nefh
Name: neurofilament, heavy polypeptide
Synonyms: NF-H, NF200, NEFH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380684
HGNC: HGNC:7737
Homologene: 40755
Cdh1
Name: cadherin 1
Synonyms: E-cadherin, Ecad, UM, uvomorulin, L-CAM, E-cad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Ptch1
Name: patched 1
Synonyms: Ptc, Patched 1, Ptc1, A230106A15Rik, wig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Plin2
Name: perilipin 2
Synonyms: Adrp, adipophilin, ADPH, Adfp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11520
HGNC: HGNC:248
Homologene: 872
Abca12
Name: ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms: 4832428G11Rik, 4833417A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74591
Homologene: 45441
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, DNA-PK, XRCC7, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Lrrc2
Name: leucine rich repeat containing 2
Synonyms: 2400002D05Rik, 4933431K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74249
Homologene: 23454
Oxsr1
Name: oxidative-stress responsive 1
Synonyms: 2810422B09Rik, 2210022N24Rik, Osr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108737
HGNC: HGNC:8508
Homologene: 31288
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20535
Homologene: 128699
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Ascc3
Name: activating signal cointegrator 1 complex subunit 3
Synonyms: ASC1p200, B630009I04Rik, Helic1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 77987
VEGA: 10
Homologene: 4973
Celf1
Name: CUGBP, Elav-like family member 1
Synonyms: CUG-BP, Brunol2, D2Wsu101e, 1600010O03Rik, CUG-BP1, Cugbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13046
HGNC: HGNC:2549
Homologene: 134102
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70797
Homologene: 19076
Fnbp4
Name: formin binding protein 4
Synonyms: FBP30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 55935
Homologene: 9087
Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms: 2410008J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69719
HGNC: HGNC:1424
Homologene: 1412
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Afdn
Name: afadin, adherens junction formation factor
Synonyms: AF6, Afadin, S-afadin, I-afadin, 5033403D15Rik, Mllt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17356
HGNC: HGNC:7137
Homologene: 21202
Bub1
Name: BUB1, mitotic checkpoint serine/threonine kinase
Synonyms: Bub1a, D2Xrf87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12235
HGNC: HGNC:1148
Homologene: 37910
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, Cd, ska26, skax26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Cyp51
Name: cytochrome P450, family 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13121
HGNC: HGNC:2649
Homologene: 55488
Zfp600
Name: zinc finger protein 600
Synonyms: Gm13164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 667666
Homologene: 133076
Camkv
Name: CaM kinase-like vesicle-associated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235604
Homologene: 56983
Cux2
Name: cut-like homeobox 2
Synonyms: Cux-2, Cux2, ENSMUSG00000072641, Cutl2, 1700051K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13048
Homologene: 22426
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A330102H22Rik, A230083H22Rik, Olfaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Havcr1
Name: hepatitis A virus cellular receptor 1
Synonyms: Tim1, TIM-1, KIM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171283
Homologene: 136301
Fam13c
Name: family with sequence similarity 13, member C
Synonyms: C030038O19Rik, 1200015N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71721
Homologene: 11490
Slc25a27
Name: solute carrier family 25, member 27
Synonyms: D530043E16Rik, Ucp4, 3632410G24Rik, 9430092A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74011
VEGA: 17
Homologene: 12523
Thsd1
Name: thrombospondin, type I, domain 1
Synonyms: 4833423O18Rik, Tmtsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56229
Homologene: 10264
Tmem204
Name: transmembrane protein 204
Synonyms: Clp24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 407831
Homologene: 36419
Cep192
Name: centrosomal protein 192
Synonyms: D430014P18Rik, 4631422C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70799
VEGA: 18
Homologene: 73526
Bik
Name: BCL2-interacting killer
Synonyms: Blk, Nbk, Biklk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12124
VEGA: 15
HGNC: HGNC:1051
Homologene: 924
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Abca4
Name: ATP-binding cassette, sub-family A (ABC1), member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Pik3r4
Name: phosphoinositide-3-kinase regulatory subunit 4
Synonyms: Vps15, p150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75669
HGNC: HGNC:8982
Homologene: 24678
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Mrgprb1
Name: MAS-related GPR, member B1
Synonyms: MrgB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233231
Homologene: 24986
Haspin
Name: histone H3 associated protein kinase
Synonyms: Gsg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14841
Homologene: 49236
Wdpcp
Name: WD repeat containing planar cell polarity effector
Synonyms: homoloc-13, AV249152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216560
Homologene: 9299
Sh3pxd2a
Name: SH3 and PX domains 2A
Synonyms: Fish, Sh3md1, Tks5, 2310014D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14218
VEGA: 19
Homologene: 7317
Serpinb1a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 1a
Synonyms: LEI, 1190005M04Rik, ovalbumin, ELANH2, M/NEI, MNEI, EIA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66222
HGNC: HGNC:3311
Homologene: 133768
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212392
Homologene: 17668
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192187
Homologene: 9035
Tom1l1
Name: target of myb1-like 1 (chicken)
Synonyms: 2310045L10Rik, Srcasm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71943
Homologene: 38055
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: Ste, EST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20860
Homologene: 101388
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Gpat2
Name: glycerol-3-phosphate acyltransferase 2, mitochondrial
Synonyms: Gpat2, A530057A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215456
Homologene: 19037
Or1j18
Name: olfactory receptor family 1 subfamily J member 18
Synonyms: GA_x6K02T2NLDC-33428755-33429693, MOR136-9, Olfr347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258945
Homologene: 51790
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Vmn2r98
Name: vomeronasal 2, receptor 98
Synonyms: EG224552
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224552
Homologene: 115024
Psg19
Name: pregnancy specific beta-1-glycoprotein 19
Synonyms: CGM7, Cea-4, Cea4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26439
Homologene: 110989
Zbbx
Name: zinc finger, B-box domain containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213234
Homologene: 11661
Fbxo43
Name: F-box protein 43
Synonyms: 4930533G20Rik, XErp1 homolog, endogenous meiotic inhibitor 2, Emi2, early mitotic inhibitor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78803
VEGA: 15
Homologene: 66393
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: 1700016J08Rik, PXR2, TRIP8b, Pex2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 58869
Homologene: 9562
Alox12
Name: arachidonate 12-lipoxygenase
Synonyms: P-12LO, Alox12p, 9930022G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11684
HGNC: HGNC:429
Homologene: 560
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, Endo180, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17534
Homologene: 4408
Fam83c
Name: family with sequence similarity 83, member C
Synonyms: 5530400B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71405
Homologene: 18669
Ccdc154
Name: coiled-coil domain containing 154
Synonyms: LOC207209, ntl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 207209
Homologene: 19361
Or10s1
Name: olfactory receptor family 10 subfamily S member 1
Synonyms: GA_x6K02T2PVTD-33772307-33773260, MOR223-4, Olfr982
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258853
VEGA: 9
Homologene: 17415
Fut9
Name: fucosyltransferase 9
Synonyms: mFUT9, mFuc-TIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Plch1
Name: phospholipase C, eta 1
Synonyms: PLCeta1, Plcl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 269437
Homologene: 88833
Pqlc3
Name: PQ loop repeat containing
Synonyms: E030024M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217430
Homologene: 16454
Or51a10
Name: olfactory receptor family 51 subfamily A member 10
Synonyms: GA_x6K02T2PBJ9-6784380-6783436, MOR13-6, Olfr642
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258326
Homologene: 17196
Toporsl
Name: topoisomerase I binding, arginine/serine-rich like
Synonyms: 4930547C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68274
Homologene: 130753
Ephb4
Name: Eph receptor B4
Synonyms: MDK2, Myk1, Htk, Tyro11, b2b2412Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13846
HGNC: HGNC:3395
Homologene: 20939
Zfp957
Name: zinc finger protein 957
Synonyms: AU017455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105590
Cfap157
Name: cilia and flagella associated protein 157
Synonyms: 1700019L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227736
Homologene: 53056
Zfp697
Name: zinc finger protein 697
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242109
Homologene: 18241
Or5ak4
Name: olfactory receptor family 5 subfamily AK member 4
Synonyms: GA_x6K02T2Q125-46808500-46807571, MOR203-7P, Olfr987
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257951
Homologene: 103791
Prss47
Name: protease, serine 47
Synonyms: LOC218304, Gm274
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218304
Homologene: 28158
Fem1a
Name: fem 1 homolog a
Synonyms: Eprap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14154
VEGA: 17
Homologene: 7713
Cyb5rl
Name: cytochrome b5 reductase-like
Synonyms: 2810410C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230582
Homologene: 45506
AF067061
Name: cDNA sequence AF067061
Synonyms: clone L4 variable group of 2-cell-stage gene family, clone L8 variable group of 2-cell-stage gene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 236546
Slc22a17
Name: solute carrier family 22 (organic cation transporter), member 17
Synonyms: 1700094C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59049
VEGA: 14
Homologene: 10684
Ccr1l1
Name: chemokine (C-C motif) receptor 1-like 1
Synonyms: MIP-1 alphaRL1, Cmkbr1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12770
VEGA: 9
HGNC: HGNC:1602
Homologene: 56388
Bola1
Name: bolA-like 1 (E. coli)
Synonyms: 1810037G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69168
Homologene: 41103
Rrnad1
Name: ribosomal RNA adenine dimethylase domain containing 1
Synonyms: BC023814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229503
Homologene: 9332
Gm3727
Name: predicted gene 3727
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 102632113
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 46,097,992 bp
  • A to C, chromosome 1 at 71,309,759 bp
  • T to G, chromosome 2 at 32,778,163 bp
  • T to A, chromosome 2 at 36,734,701 bp
  • A to T, chromosome 2 at 85,331,102 bp
  • T to A, chromosome 2 at 90,767,399 bp
  • T to A, chromosome 2 at 90,987,828 bp
  • G to A, chromosome 2 at 127,428,291 bp
  • T to C, chromosome 2 at 127,801,281 bp
  • T to A, chromosome 2 at 155,831,524 bp
  • C to T, chromosome 3 at 5,403,358 bp
  • T to A, chromosome 3 at 32,953,132 bp
  • C to T, chromosome 3 at 63,698,482 bp
  • G to A, chromosome 3 at 75,112,107 bp
  • A to T, chromosome 3 at 87,927,053 bp
  • A to T, chromosome 3 at 96,197,201 bp
  • C to A, chromosome 3 at 98,428,014 bp
  • A to G, chromosome 3 at 122,112,399 bp
  • T to A, chromosome 4 at 25,619,733 bp
  • T to A, chromosome 4 at 25,619,734 bp
  • T to A, chromosome 4 at 52,612,072 bp
  • A to T, chromosome 4 at 86,668,432 bp
  • C to T, chromosome 4 at 107,068,683 bp
  • A to T, chromosome 4 at 146,196,918 bp
  • A to T, chromosome 5 at 3,713,210 bp
  • T to G, chromosome 5 at 4,086,594 bp
  • A to G, chromosome 5 at 24,431,316 bp
  • A to G, chromosome 5 at 31,062,220 bp
  • A to T, chromosome 5 at 87,576,332 bp
  • A to G, chromosome 5 at 121,887,477 bp
  • A to G, chromosome 5 at 137,354,426 bp
  • A to C, chromosome 6 at 134,459,283 bp
  • T to A, chromosome 7 at 18,796,986 bp
  • T to C, chromosome 7 at 48,447,322 bp
  • T to C, chromosome 7 at 81,295,768 bp
  • T to C, chromosome 7 at 104,049,638 bp
  • G to T, chromosome 8 at 22,238,522 bp
  • T to C, chromosome 8 at 45,942,839 bp
  • T to C, chromosome 8 at 106,664,321 bp
  • A to G, chromosome 9 at 40,074,915 bp
  • T to A, chromosome 9 at 105,672,785 bp
  • C to A, chromosome 9 at 107,945,600 bp
  • A to C, chromosome 9 at 110,979,577 bp
  • A to C, chromosome 9 at 119,294,432 bp
  • A to G, chromosome 9 at 123,977,654 bp
  • T to G, chromosome 10 at 50,721,839 bp
  • A to G, chromosome 10 at 70,542,693 bp
  • A to C, chromosome 10 at 123,042,364 bp
  • T to C, chromosome 11 at 4,943,872 bp
  • T to G, chromosome 11 at 21,691,884 bp
  • A to G, chromosome 11 at 46,778,552 bp
  • A to G, chromosome 11 at 55,303,716 bp
  • A to G, chromosome 11 at 69,903,221 bp
  • A to T, chromosome 11 at 70,242,572 bp
  • A to C, chromosome 11 at 73,136,630 bp
  • A to G, chromosome 11 at 90,649,895 bp
  • G to A, chromosome 11 at 104,751,862 bp
  • G to A, chromosome 11 at 105,348,431 bp
  • G to A, chromosome 12 at 16,989,839 bp
  • T to C, chromosome 13 at 32,850,414 bp
  • T to G, chromosome 13 at 63,524,959 bp
  • A to T, chromosome 13 at 65,045,073 bp
  • A to T, chromosome 13 at 120,264,097 bp
  • T to A, chromosome 14 at 7,264,625 bp
  • A to T, chromosome 14 at 31,168,435 bp
  • A to T, chromosome 14 at 54,908,825 bp
  • A to C, chromosome 14 at 79,213,613 bp
  • C to A, chromosome 15 at 36,158,048 bp
  • A to G, chromosome 15 at 83,541,423 bp
  • C to T, chromosome 16 at 15,687,348 bp
  • A to G, chromosome 16 at 32,750,476 bp
  • T to G, chromosome 17 at 13,890,949 bp
  • A to G, chromosome 17 at 19,081,291 bp
  • G to A, chromosome 17 at 25,080,592 bp
  • T to A, chromosome 17 at 25,170,890 bp
  • A to G, chromosome 17 at 43,657,772 bp
  • A to G, chromosome 17 at 56,257,686 bp
  • T to G, chromosome 17 at 57,419,338 bp
  • T to C, chromosome 18 at 67,860,523 bp
  • A to G, chromosome 19 at 17,120,182 bp
  • A to T, chromosome 19 at 47,278,355 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2165 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040168-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.