Strain Name:
C57BL/6J-MtgxR2172Btlr/Mmmh
Stock Number:
040174-MU
Citation ID:
RRID:MMRRC_040174-MU
Other Names:
R2172 (G1), C57BL/6J-MtgxR2172Btlr
Major Collection:

Gene Information

Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Atp1a1
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms: Atpa-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11928
HGNC: HGNC:799
Homologene: 564
Jarid2
Name: jumonji, AT rich interactive domain 2
Synonyms: Jmj, jumonji
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16468
HGNC: HGNC:6196
Homologene: 31279
Rfx3
Name: regulatory factor X, 3 (influences HLA class II expression)
Synonyms: C230093O12Rik, MRFX3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19726
HGNC: HGNC:9984
Homologene: 7917
Virma
Name: vir like m6A methyltransferase associated
Synonyms: 1110037F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66185
Homologene: 41043
Setd2
Name: SET domain containing 2
Synonyms: KMT3A, 4921524K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235626
Homologene: 56493
Lsm3
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
Synonyms: 6030401D18Rik, 1010001J12Rik, USS2, SMX4, 2610005D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67678
Homologene: 6548
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382038
Homologene: 8859
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227800
Homologene: 49301
Inppl1
Name: inositol polyphosphate phosphatase-like 1
Synonyms: SHIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16332
HGNC: HGNC:6080
Homologene: 1204
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Arfip2
Name: ADP-ribosylation factor interacting protein 2
Synonyms: 2310002N04Rik, Arfaptin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76932
Homologene: 8234
Otud7b
Name: OTU domain containing 7B
Synonyms: 2900060B22Rik, 4930463P07Rik, Za20d1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229603
Homologene: 10624
Puf60
Name: poly-U binding splicing factor 60
Synonyms: 2410104I19Rik, 2810454F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67959
VEGA: 15
Homologene: 8614
Il15ra
Name: interleukin 15 receptor, alpha chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16169
HGNC: HGNC:5978
Homologene: 1650
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12032
Homologene: 7244
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: 9030408O17Rik, Mcmdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71567
VEGA: 10
Homologene: 13546
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, A930005E13Rik, 1810009A16Rik, LOC381562, D930005K06Rik, Zubr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69116
Homologene: 10804
Pcx
Name: pyruvate carboxylase
Synonyms: Pc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18563
VEGA: 19
HGNC: HGNC:8636
Homologene: 5422
Ibsp
Name: integrin binding sialoprotein
Synonyms: BSP, Bsp2, bone sialoprotein, Bsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 15891
HGNC: HGNC:5341
Homologene: 3644
Egfr
Name: epidermal growth factor receptor
Synonyms: Errb1, Wa5, 9030024J15Rik, Erbb, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13649
HGNC: HGNC:3236
Homologene: 74545
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VRL-2, Trp12, VROAC, OTRPC4, VR-OAC, 0610033B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 63873
Homologene: 11003
Dpep2
Name: dipeptidase 2
Synonyms: F630103D06Rik, MBD-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319446
Homologene: 49703
Mmp27
Name: matrix metallopeptidase 27
Synonyms: LOC234911
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234911
Homologene: 23345
Srebf1
Name: sterol regulatory element binding transcription factor 1
Synonyms: SREBP-1, SREBP-1a, SREBP-1c, ADD-1, SREBP1c, bHLHd1, SREBP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20787
Homologene: 3079
Tln1
Name: talin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21894
Homologene: 21267
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 29871
Homologene: 32146
Hnrnph1
Name: heterogeneous nuclear ribonucleoprotein H1
Synonyms: E430005G16Rik, Hnrph1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 59013
HGNC: HGNC:5041
Homologene: 31318
Tm9sf3
Name: transmembrane 9 superfamily member 3
Synonyms: Smbp, 1810073M23Rik, 2810031D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107358
VEGA: 19
Homologene: 10588
Pomgnt1
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
Synonyms: 0610016I07Rik, 4930467B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68273
Homologene: 9806
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Gpr155
Name: G protein-coupled receptor 155
Synonyms: F730029F15Rik, DEPDC3, PGR22, 1110017O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68526
Homologene: 16584
Skor1
Name: SKI family transcriptional corepressor 1
Synonyms: Lbxcor1, C230094B15Rik, Corl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 207667
Homologene: 18175
Nacc2
Name: nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Synonyms: 0610020I02Rik, Btbd14a, C030048H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67991
Homologene: 75239
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: E030006K04Rik, Centd3, DRAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106952
VEGA: 18
Homologene: 11199
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Gsap
Name: gamma-secretase activating protein
Synonyms: A530088I07Rik, Pion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212167
Homologene: 45504
Sharpin
Name: SHANK-associated RH domain interacting protein
Synonyms: SIPL1, cpdm, 0610041B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 106025
Homologene: 11918
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668940
Homologene: 66117
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224224
Homologene: 9439
Atg9a
Name: autophagy related 9A
Synonyms: Apg9l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 245860
Homologene: 34495
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Zfp329
Name: zinc finger protein 329
Synonyms: 4632409L22Rik, 2810439M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67230
Homologene: 23459
Sh2d4a
Name: SH2 domain containing 4A
Synonyms: 2210402M20Rik, SH2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72281
Homologene: 11117
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: 1110062M20Rik, ORP-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99031
Homologene: 101447
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1, 6330416M19Rik, Mtap-1, Mtap1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Nprl3
Name: nitrogen permease regulator-like 3
Synonyms: m(alpha)RE, HS-40, Mare, HS-26, Phg, -14 gene, Prox1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17168
Homologene: 8091
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: Dnahc7b, LOC227058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227058
Homologene: 41287
Tecpr1
Name: tectonin beta-propeller repeat containing 1
Synonyms: 2210010N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70381
Homologene: 9120
Tufm
Name: Tu translation elongation factor, mitochondrial
Synonyms: C76308, EF-TuMT, 2300002G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233870
Homologene: 2490
Klhdc7a
Name: kelch domain containing 7A
Synonyms: B230308G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242721
Homologene: 17567
Lrrc49
Name: leucine rich repeat containing 49
Synonyms: D430025H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102747
Homologene: 9782
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230815
Homologene: 69303
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320696
Homologene: 18560
Srrd
Name: SRR1 domain containing
Synonyms: Srr1, 2810002G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70118
Homologene: 33447
Dsc2
Name: desmocollin 2
Synonyms: Dsc2a, Dsc2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13506
HGNC: HGNC:3036
Homologene: 8397
Zfp683
Name: zinc finger protein 683
Synonyms: Hobit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100503878
Homologene: null
Slc41a2
Name: solute carrier family 41, member 2
Synonyms: A230035L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 338365
Homologene: 9870
Ints5
Name: integrator complex subunit 5
Synonyms: 1110055N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 109077
Homologene: 35303
Pcsk4
Name: proprotein convertase subtilisin/kexin type 4
Synonyms: PC4, SPC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18551
HGNC: HGNC:8746
Homologene: 22495
Fastkd1
Name: FAST kinase domains 1
Synonyms: 5330408N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320720
Homologene: 36420
Hecw1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Synonyms: E130207I19Rik, NEDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 94253
VEGA: 13
Homologene: 9004
Gabrd
Name: gamma-aminobutyric acid (GABA) A receptor, subunit delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14403
HGNC: HGNC:4084
Homologene: 55489
Qars
Name: glutaminyl-tRNA synthetase
Synonyms: 1200016L19Rik, 1110018N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 97541
HGNC: HGNC:9751
Homologene: 133975
Ift57
Name: intraflagellar transport 57
Synonyms: MHS4R2, 4833420A15Rik, Esrrbl1, HIPPI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 73916
Homologene: 32383
Olfr478
Name: olfactory receptor 478
Synonyms: GA_x6K02T2PBJ9-10361879-10360935, MOR204-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258729
HGNC: null
Homologene: 128076
Marveld3
Name: MARVEL (membrane-associating) domain containing 3
Synonyms: MARVD3, 1810006A16Rik, Mrvldc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73608
Homologene: 12504
Vmn2r32
Name: vomeronasal 2, receptor 32
Synonyms: V2r5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22311
HGNC: null
Homologene: 113703
P2rx3
Name: purinergic receptor P2X, ligand-gated ion channel, 3
Synonyms: P2X3, 4930513E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228139
HGNC: HGNC:8534
Homologene: 1922
Rnf25
Name: ring finger protein 25
Synonyms: 0610009H16Rik, AO7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 57751
Homologene: 11193
Gm14295
Name: predicted gene 14295
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100039123
HGNC: null
Homologene: 133105
Sparc
Name: secreted acidic cysteine rich glycoprotein
Synonyms: BM-40, osteonectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20692
Homologene: 31132
Samd14
Name: sterile alpha motif domain containing 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217125
Homologene: 17130
Mettl4
Name: methyltransferase like 4
Synonyms: HsT661, 2410198H06Rik, A730091E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76781
VEGA: 17
Homologene: 35305
Gm10696
Name: predicted gene 10696
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100043188
HGNC: null
Homologene: 128308
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 14,881,656 bp
  • A to G, chromosome 1 at 46,124,512 bp
  • T to C, chromosome 1 at 74,599,149 bp
  • C to A, chromosome 1 at 75,185,685 bp
  • A to G, chromosome 2 at 11,723,571 bp
  • A to C, chromosome 2 at 26,060,223 bp
  • C to T, chromosome 2 at 37,556,317 bp
  • A to G, chromosome 2 at 69,700,133 bp
  • C to T, chromosome 2 at 73,382,127 bp
  • G to A, chromosome 2 at 76,569,014 bp
  • T to C, chromosome 2 at 85,021,719 bp
  • G to T, chromosome 2 at 121,307,932 bp
  • T to C, chromosome 2 at 155,621,450 bp
  • G to A, chromosome 2 at 176,811,102 bp
  • T to A, chromosome 3 at 87,996,581 bp
  • T to G, chromosome 3 at 94,176,298 bp
  • T to G, chromosome 3 at 96,153,520 bp
  • T to G, chromosome 3 at 101,590,548 bp
  • A to T, chromosome 4 at 11,527,843 bp
  • T to A, chromosome 4 at 43,545,721 bp
  • C to T, chromosome 4 at 116,156,018 bp
  • T to C, chromosome 4 at 120,463,068 bp
  • C to T, chromosome 4 at 134,055,795 bp
  • G to C, chromosome 4 at 134,703,438 bp
  • T to C, chromosome 4 at 139,473,532 bp
  • T to A, chromosome 4 at 139,965,810 bp
  • T to A, chromosome 4 at 155,386,562 bp
  • G to A, chromosome 5 at 21,222,440 bp
  • A to T, chromosome 5 at 92,632,508 bp
  • T to C, chromosome 5 at 104,310,430 bp
  • A to G, chromosome 5 at 112,341,122 bp
  • G to A, chromosome 5 at 114,644,710 bp
  • G to T, chromosome 5 at 144,196,417 bp
  • A to T, chromosome 5 at 144,211,456 bp
  • T to A, chromosome 6 at 58,887,437 bp
  • T to C, chromosome 6 at 91,522,272 bp
  • T to C, chromosome 6 at 108,515,743 bp
  • T to C, chromosome 7 at 7,474,615 bp
  • A to G, chromosome 7 at 12,810,767 bp
  • G to A, chromosome 7 at 101,831,924 bp
  • T to A, chromosome 7 at 105,637,988 bp
  • A to T, chromosome 7 at 108,031,467 bp
  • A to G, chromosome 7 at 126,488,847 bp
  • T to C, chromosome 8 at 68,296,664 bp
  • A to G, chromosome 8 at 105,988,998 bp
  • A to C, chromosome 8 at 109,961,846 bp
  • A to G, chromosome 8 at 110,582,049 bp
  • A to G, chromosome 8 at 124,031,102 bp
  • T to A, chromosome 9 at 7,577,378 bp
  • A to G, chromosome 9 at 60,602,682 bp
  • C to A, chromosome 9 at 63,145,122 bp
  • T to C, chromosome 9 at 108,109,992 bp
  • C to T, chromosome 9 at 108,509,200 bp
  • G to A, chromosome 9 at 110,549,844 bp
  • T to C, chromosome 10 at 53,548,574 bp
  • C to A, chromosome 10 at 80,323,668 bp
  • T to C, chromosome 10 at 83,283,774 bp
  • C to T, chromosome 10 at 107,590,994 bp
  • C to T, chromosome 11 at 16,911,562 bp
  • T to A, chromosome 11 at 32,234,894 bp
  • T to A, chromosome 11 at 50,382,816 bp
  • G to A, chromosome 11 at 55,395,801 bp
  • T to C, chromosome 11 at 60,206,502 bp
  • G to T, chromosome 11 at 66,072,779 bp
  • G to T, chromosome 11 at 95,014,391 bp
  • T to A, chromosome 13 at 14,377,706 bp
  • T to C, chromosome 13 at 44,902,539 bp
  • A to T, chromosome 15 at 76,070,464 bp
  • C to A, chromosome 15 at 76,350,666 bp
  • T to G, chromosome 16 at 49,759,340 bp
  • T to A, chromosome 16 at 56,236,773 bp
  • A to G, chromosome 17 at 94,733,163 bp
  • A to G, chromosome 18 at 20,045,502 bp
  • T to A, chromosome 18 at 37,990,560 bp
  • G to A, chromosome 19 at 4,620,881 bp
  • C to T, chromosome 19 at 8,896,282 bp
  • G to A, chromosome 19 at 27,815,494 bp
  • C to T, chromosome 19 at 41,217,420 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2172 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040174-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.