Strain Name:
C57BL/6J-MtgxR2174Btlr/Mmmh
Stock Number:
040176-MU
Citation ID:
RRID:MMRRC_040176-MU
Other Names:
R2174 (G1), C57BL/6J-MtgxR2174Btlr
Major Collection:

Strain Information

Ubn2
Name: ubinuclein 2
Synonyms: 6030408G03Rik, 2900060J04Rik, D130059P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320538
Homologene: 45564
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20269
Homologene: 56005
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Clasp1
Name: CLIP associating protein 1
Synonyms: 5730583A19Rik, 1700030C23Rik, mCLASP1, CLASP1alpha, CLASP1, B130045P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76707
Homologene: 41024
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Nptn
Name: neuroplastin
Synonyms: Sdfr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20320
Homologene: 105617
Trappc12
Name: trafficking protein particle complex 12
Synonyms: CGI-87, D930014A20Rik, Ttc15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217449
VEGA: 12
Homologene: 34805
Xpo4
Name: exportin 4
Synonyms: B430309A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57258
Homologene: 10733
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100683
Homologene: 39246
Scaper
Name: S phase cyclin A-associated protein in the ER
Synonyms: D530014O03Rik, Zfp291
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244891
VEGA: 9
Homologene: 32488
Sap130
Name: Sin3A associated protein
Synonyms: 2610304F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 269003
VEGA: 18
Homologene: 11577
Nav2
Name: neuron navigator 2
Synonyms: POMFIL2, Unc53H2, HELAD1, RAINB2, 5330421F07Rik, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 78286
Homologene: 52330
Depdc1b
Name: DEP domain containing 1B
Synonyms: XTP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218581
Homologene: 10157
Fnta
Name: farnesyltransferase, CAAX box, alpha
Synonyms: FTA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14272
HGNC: HGNC:3782
Homologene: 1534
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 5730590C14Rik, 3526402J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77097
Homologene: 64680
Msr1
Name: macrophage scavenger receptor 1
Synonyms: SR-AII, SR-AI, MSR-A, Scara1, Scvr, MRS-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20288
HGNC: HGNC:7376
Homologene: 12822
Cntn2
Name: contactin 2
Synonyms: Tax, TAG-1, axonin, D130012K04Rik, TAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Ier5
Name: immediate early response 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15939
HGNC: HGNC:5393
Homologene: 7778
Pan3
Name: PAN3 poly(A) specific ribonuclease subunit
Synonyms: 2700050F09Rik, A430027N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72587
Homologene: 6372
Fzd3
Name: frizzled class receptor 3
Synonyms: Fz3, D930050A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14365
HGNC: HGNC:4041
Homologene: 23004
Map3k1
Name: mitogen-activated protein kinase kinase kinase 1
Synonyms: MEKK1, Mekk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 26401
HGNC: HGNC:6848
Homologene: 8056
Tra2a
Name: transformer 2 alpha
Synonyms: mAWMS1, 1500010G04Rik, G430041M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 101214
Homologene: 40866
Rfwd3
Name: ring finger and WD repeat domain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234736
Homologene: 41230
Gpx8
Name: glutathione peroxidase 8 (putative)
Synonyms: 2310016C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69590
VEGA: 13
Homologene: 88454
Dnajc1
Name: DnaJ heat shock protein family (Hsp40) member C1
Synonyms: MTJ1, Dnajl1, ERdj1, 4733401K02Rik, D230036H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13418
Homologene: 7293
Kif13a
Name: kinesin family member 13A
Synonyms: N-3 kinesin, 4930505I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Zdhhc5
Name: zinc finger, DHHC domain containing 5
Synonyms: Zisp, 1110032A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228136
Homologene: 9147
Hectd3
Name: HECT domain E3 ubiquitin protein ligase 3
Synonyms: 1700064K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76608
Homologene: 18426
Inpp4a
Name: inositol polyphosphate-4-phosphatase, type I
Synonyms: 107kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269180
HGNC: HGNC:6074
Homologene: 2871
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: LOC381127, D930044O18Rik, D430002O22Rik, C230079D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 211961
Homologene: 19371
Grm2
Name: glutamate receptor, metabotropic 2
Synonyms: mGluR2, 4930441L02Rik, Gprc1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108068
HGNC: HGNC:4594
Homologene: 20229
Adarb1
Name: adenosine deaminase, RNA-specific, B1
Synonyms: RED1, ADAR2, D10Bwg0447e, 1700057H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110532
HGNC: HGNC:226
Homologene: 8280
Pthlh
Name: parathyroid hormone-like peptide
Synonyms: Pthrp, parathyroid hormone-like hormone, PTH-like, PTH-related peptide, parathyroid hormone-related peptide, parathyroid hormone-related protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19227
HGNC: HGNC:9607
Homologene: 2113
Nlrp4a
Name: NLR family, pyrin domain containing 4A
Synonyms: Nalp-eta, E330028A19Rik, Nalp4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243880
Homologene: 79696
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Or9s23
Name: olfactory receptor family 9 subfamily S member 23
Synonyms: GA_x6K02T2R7CC-81180849-81179878, MOR208-1, Olfr1413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 259039
Homologene: 128165
Gckr
Name: glucokinase regulatory protein
Synonyms: GKRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231103
HGNC: HGNC:4196
Homologene: 1139
Casc1
Name: cancer susceptibility candidate 1
Synonyms: Las1, A230084G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320662
Homologene: 41242
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74670
Homologene: 134342
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: 0710001E20Rik, LGL3, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78808
Homologene: 16402
Atp2c2
Name: ATPase, Ca++ transporting, type 2C, member 2
Synonyms: 1810010G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69047
Homologene: 73463
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Naip-rs4, Birc1f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Gbp6
Name: guanylate binding protein 6
Synonyms: Mpa2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100702
Homologene: 128731
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320118
Homologene: 27057
Gtf3c5
Name: general transcription factor IIIC, polypeptide 5
Synonyms: TFiiiC2-63, TFIIICepsilon, TFIIIC63, 2700084A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70239
HGNC: HGNC:4668
Homologene: 40806
Capn2
Name: calpain 2
Synonyms: m-calpain, Capa-2, Capa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12334
HGNC: HGNC:1479
Homologene: 1326
Unc5d
Name: unc-5 netrin receptor D
Synonyms: Unc5h4, D930029E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 210801
Homologene: 15450
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Ddx60
Name: DExD/H box helicase 60
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234311
Homologene: 23031
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Smc1b
Name: structural maintenance of chromosomes 1B
Synonyms: SMC1beta, Smc1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 140557
VEGA: 15
Homologene: 13786
Cacnb2
Name: calcium channel, voltage-dependent, beta 2 subunit
Synonyms: Cchb2, Cavbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12296
HGNC: HGNC:1402
Homologene: 75191
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432486
Homologene: 32576
Fanca
Name: Fanconi anemia, complementation group A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14087
HGNC: HGNC:3582
Homologene: 108
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105841
Homologene: 28254
Zbbx
Name: zinc finger, B-box domain containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 213234
Homologene: 11661
Cfap20dc
Name: CFAP20 domain containing
Synonyms: 4930452B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74430
Homologene: 18873
Bpifa1
Name: BPI fold containing family A, member 1
Synonyms: SPLUNC1, Plunc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18843
Homologene: 7895
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320696
Homologene: 18560
Tbc1d31
Name: TBC1 domain family, member 31
Synonyms: LOC210544, D330013L20Rik, Wdr67
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 210544
Homologene: 17089
Myoz3
Name: myozenin 3
Synonyms: calsarcin-3, Fatz-3, 4833419K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 170947
Homologene: 15782
Tmem67
Name: transmembrane protein 67
Synonyms: 5330408M12Rik, b2b1291.1Clo, b2b1163.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329795
Homologene: 71886
Mtmr10
Name: myotubularin related protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233315
Homologene: 9822
Cenpo
Name: centromere protein O
Synonyms: D12Ertd482e, 8430427C03Rik, 2810429O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 52504
Homologene: 49760
Tekt3
Name: tektin 3
Synonyms: 4933407G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71062
Homologene: 12896
Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Synonyms: Ahd5, Ahd-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11669
HGNC: HGNC:404
Homologene: 55480
Ndufaf6
Name: NADH:ubiquinone oxidoreductase complex assembly factor 6
Synonyms: 2310030N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76947
Homologene: 43831
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
Gm5724
Name: predicted gene 5724
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435927
Sowahb
Name: sosondowah ankyrin repeat domain family member B
Synonyms: 5730467H21Rik, Ankrd56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78088
Homologene: 18429
Grin2d
Name: glutamate receptor, ionotropic, NMDA2D (epsilon 4)
Synonyms: NMDAR2D, NR2D, GluRepsilon4, GluN2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14814
HGNC: HGNC:4588
Homologene: 648
Epha10
Name: Eph receptor A10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230735
Homologene: 67804
Sap25
Name: sin3 associated polypeptide
Synonyms: 25 kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 751865
Homologene: 104044
Gm6741
Name: predicted gene 6741
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627235
VEGA: 17
Asnsd1
Name: asparagine synthetase domain containing 1
Synonyms: 2210409M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70396
Homologene: 6564
Ccdc59
Name: coiled-coil domain containing 59
Synonyms: 2300004H16Rik, D10Ertd718e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52713
Homologene: 32208
AC168070.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
1600014C10Rik
Name: RIKEN cDNA 1600014C10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72244
Homologene: 41744
Rpl31-ps17
Name: ribosomal protein L31, pseudogene 17
Synonyms: Gm16382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 673582
Mbl2
Name: mannose-binding lectin (protein C) 2
Synonyms: MBL-C, MBL, MBP-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17195
VEGA: 19
HGNC: HGNC:6922
Homologene: 110436
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 37,396,130 bp
  • A to T, chromosome 1 at 53,347,601 bp
  • A to G, chromosome 1 at 92,573,657 bp
  • A to G, chromosome 1 at 118,560,095 bp
  • C to T, chromosome 1 at 132,515,535 bp
  • G to T, chromosome 1 at 155,098,853 bp
  • A to T, chromosome 1 at 182,479,725 bp
  • C to T, chromosome 2 at 14,958,767 bp
  • T to C, chromosome 2 at 18,307,951 bp
  • T to C, chromosome 2 at 28,567,775 bp
  • T to C, chromosome 2 at 59,843,833 bp
  • T to A, chromosome 2 at 65,507,206 bp
  • A to C, chromosome 2 at 84,702,463 bp
  • T to C, chromosome 2 at 154,147,233 bp
  • A to G, chromosome 3 at 17,230,841 bp
  • T to G, chromosome 3 at 75,052,414 bp
  • T to C, chromosome 4 at 11,070,228 bp
  • C to T, chromosome 4 at 12,063,730 bp
  • A to T, chromosome 4 at 116,999,701 bp
  • T to C, chromosome 4 at 124,913,648 bp
  • A to G, chromosome 5 at 21,582,048 bp
  • T to C, chromosome 5 at 31,327,009 bp
  • T to A, chromosome 5 at 92,649,927 bp
  • T to C, chromosome 5 at 93,044,425 bp
  • T to C, chromosome 5 at 105,274,350 bp
  • T to C, chromosome 5 at 121,572,668 bp
  • T to G, chromosome 5 at 137,642,629 bp
  • C to A, chromosome 5 at 144,821,855 bp
  • T to C, chromosome 5 at 147,450,653 bp
  • T to A, chromosome 6 at 38,470,141 bp
  • T to C, chromosome 6 at 49,250,927 bp
  • A to T, chromosome 6 at 141,727,593 bp
  • T to C, chromosome 6 at 145,175,170 bp
  • G to A, chromosome 6 at 147,257,012 bp
  • T to C, chromosome 7 at 26,449,424 bp
  • T to C, chromosome 7 at 38,194,828 bp
  • T to A, chromosome 7 at 45,853,192 bp
  • T to A, chromosome 7 at 49,452,663 bp
  • T to A, chromosome 7 at 64,336,764 bp
  • A to T, chromosome 8 at 26,013,470 bp
  • A to T, chromosome 8 at 28,694,540 bp
  • A to G, chromosome 8 at 39,631,340 bp
  • A to G, chromosome 8 at 61,956,141 bp
  • G to T, chromosome 8 at 62,017,200 bp
  • A to G, chromosome 8 at 111,283,343 bp
  • T to C, chromosome 8 at 119,752,934 bp
  • A to G, chromosome 8 at 123,271,270 bp
  • A to T, chromosome 9 at 55,859,037 bp
  • T to A, chromosome 9 at 58,651,045 bp
  • T to C, chromosome 9 at 106,060,132 bp
  • T to C, chromosome 9 at 106,647,795 bp
  • T to A, chromosome 10 at 9,835,846 bp
  • A to G, chromosome 10 at 77,295,798 bp
  • T to A, chromosome 10 at 88,434,044 bp
  • A to T, chromosome 10 at 105,841,527 bp
  • A to T, chromosome 10 at 107,705,553 bp
  • A to T, chromosome 11 at 63,094,688 bp
  • A to G, chromosome 11 at 105,910,309 bp
  • A to T, chromosome 11 at 116,224,206 bp
  • T to C, chromosome 12 at 4,217,318 bp
  • A to G, chromosome 12 at 28,747,381 bp
  • C to T, chromosome 12 at 54,701,612 bp
  • A to G, chromosome 13 at 46,769,176 bp
  • C to A, chromosome 13 at 100,298,987 bp
  • A to T, chromosome 13 at 108,362,253 bp
  • G to C, chromosome 13 at 111,752,482 bp
  • G to A, chromosome 13 at 113,045,606 bp
  • T to C, chromosome 14 at 8,558,109 bp
  • T to A, chromosome 14 at 34,060,400 bp
  • A to G, chromosome 14 at 57,590,090 bp
  • T to C, chromosome 14 at 65,212,231 bp
  • A to G, chromosome 15 at 57,951,741 bp
  • A to T, chromosome 15 at 73,555,305 bp
  • A to G, chromosome 15 at 85,121,851 bp
  • A to T, chromosome 16 at 15,734,922 bp
  • T to A, chromosome 17 at 21,992,823 bp
  • A to G, chromosome 17 at 91,236,904 bp
  • T to G, chromosome 18 at 22,453,644 bp
  • T to C, chromosome 18 at 31,677,479 bp
  • A to G, chromosome 18 at 31,983,557 bp
  • T to C, chromosome 18 at 60,590,224 bp
  • G to A, chromosome 19 at 30,234,012 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2174 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040176-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.