Strain Name:
C57BL/6J-MtgxR2232Btlr/Mmmh
Stock Number:
040233-MU
Citation ID:
RRID:MMRRC_040233-MU
Other Names:
R2232 (G1), C57BL/6J-MtgxR2232Btlr
Major Collection:

Strain Information

Trmt9b
Name: tRNA methyltransferase 9B
Synonyms: 6430573F11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319582
Homologene: 35306
Nes
Name: nestin
Synonyms: Ifaprc2, Marc2, ESTM46, RC2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Synonyms: Htr2, Htr-2, 5-HT2A receptor
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 15558
VEGA: 14
HGNC: HGNC:5293
Homologene: 68073
Pkp4
Name: plakophilin 4
Synonyms: 5031422I09Rik, 9430019K17Rik, Armrp, p0071
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Mindy3
Name: MINDY lysine 48 deubiquitinase 3
Synonyms: Fam188a, 5830410F13Rik, 2310047O13Rik, 1810041E18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66960
Homologene: 11478
Kansl2
Name: KAT8 regulatory NSL complex subunit 2
Synonyms: 2310037I24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69612
VEGA: 15
Homologene: 32367
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: KMT1D, 9230102N17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77683
Homologene: 11698
Dennd2b
Name: DENN domain containing 2B
Synonyms: Denn2b, 2010004M01Rik, St5, 2610305K15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76954
Homologene: 3951
Serpinb6a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6a
Synonyms: D330015H01Rik, Spi3, ovalbumin, 4930482L21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20719
HGNC: HGNC:8950
Homologene: 20956
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: D16Ium21, D16Ium21e, TPRD, 2610202A04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22129
Homologene: 2487
Acly
Name: ATP citrate lyase
Synonyms: A730098H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104112
HGNC: HGNC:115
Homologene: 854
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Copb1
Name: coatomer protein complex, subunit beta 1
Synonyms: Copb1, 2610019B04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70349
HGNC: HGNC:2231
Homologene: 5664
Metap1
Name: methionyl aminopeptidase 1
Synonyms: 1700029C17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 75624
Homologene: 6488
Akap9
Name: A kinase anchor protein 9
Synonyms: G1-448-15, 5730481H23Rik, mei2-5, AKAP450, repro12
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Myo1b
Name: myosin IB
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Ppp3r1
Name: protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Synonyms: Cnb1, CaNB1, PP2B beta 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19058
HGNC: HGNC:9317
Homologene: 68099
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: dgkd-2, DGKdelta
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Kri1
Name: KRI1 homolog
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215194
Homologene: 133742
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Sp2
Name: Sp2 transcription factor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78912
Homologene: 2340
Prpf39
Name: pre-mRNA processing factor 39
Synonyms: Srcs1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 328110
Homologene: 32377
Il17re
Name: interleukin 17 receptor E
Synonyms: Il25r
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 57890
Homologene: 17109
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225115
Homologene: 25090
Scin
Name: scinderin
Synonyms: adseverin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20259
Homologene: 36296
Adgrf4
Name: adhesion G protein-coupled receptor F4
Synonyms: 4632435A09Rik, Gpr115
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78249
Homologene: 51953
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1565Clo, b2b3491Clo, Mdnah5, b2b1154Clo, b2b1537Clo, Dnahc5, b2b1134Clo
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Tnfsf14
Name: tumor necrosis factor (ligand) superfamily, member 14
Synonyms: LIGHT, HVEM-L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50930
VEGA: 17
Homologene: 2822
Tet3
Name: tet methylcytosine dioxygenase 3
Synonyms: B430006D22Rik, D230004J03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194388
Homologene: 35360
Zscan18
Name: zinc finger and SCAN domain containing 18
Synonyms: EG232875
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232875
Homologene: 122136
Asns
Name: asparagine synthetase
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27053
HGNC: HGNC:753
Homologene: 69113
Slc8a3
Name: solute carrier family 8 (sodium/calcium exchanger), member 3
Synonyms: Ncx3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110893
Homologene: 62645
Kif21a
Name: kinesin family member 21A
Synonyms: N-5 kinesin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16564
VEGA: 15
Homologene: 56761
Or10j7
Name: olfactory receptor family 10 subfamily J member 7
Synonyms: GA_x6K02T2R7CC-664297-665229, Olfr1406, MOR267-5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258758
Homologene: 133644
Ghrhr
Name: growth hormone releasing hormone receptor
Synonyms: Ghrfr
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14602
HGNC: HGNC:4266
Homologene: 640
Ankra2
Name: ankyrin repeat family A member 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68558
Homologene: 11312
4932425I24Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Fam227a
Name: family with sequence similarity 227, member A
Synonyms: 4933432B09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75729
Homologene: 123434
Usp20
Name: ubiquitin specific peptidase 20
Synonyms: 1700055M05Rik, Vdu2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74270
Homologene: 4861
Ninl
Name: ninein-like
Synonyms: LOC381388, LOC381387, 4930519N13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78177
Homologene: 57024
Ergic3
Name: ERGIC and golgi 3
Synonyms: Sdbcag84, NY-BR-84, 2310015B14Rik, CGI-54, D2Ucla1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66366
Homologene: 5289
Serpina3m
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3M
Synonyms: Spi-2rs1, contrapsin-like, 3e46, MMCM7, alpha-1 antiproteinase, Spi2-rs1, Spi2.4, MMSPi2.4, antitrypsin, Spi-2l
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20717
HGNC: HGNC:16
Homologene: 111129
Shc4
Name: SHC (Src homology 2 domain containing) family, member 4
Synonyms: 9930029B02Rik, LOC271849, 6230417E10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271849
Homologene: 19567
Oaz3
Name: ornithine decarboxylase antizyme 3
Synonyms: AZ3, ornithine decarboxylase antizyme in testis, Oaz-t, AZ-3, antizyme 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 53814
HGNC: HGNC:8097
Homologene: 9410
Mcpt9
Name: mast cell protease 9
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17232
VEGA: 14
Homologene: 115745
Prr5
Name: proline rich 5 (renal)
Synonyms: C030017C09Rik, Protor-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109270
Homologene: 17132
Proz
Name: protein Z, vitamin K-dependent plasma glycoprotein
Synonyms: 1300015B06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66901
HGNC: HGNC:9460
Homologene: 2890
Pacs2
Name: phosphofurin acidic cluster sorting protein 2
Synonyms: Pacs1l, 6720425G15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217893
VEGA: 12
Homologene: 15016
Spmap2l
Name: sperm microtubule associated protein 2 like
Synonyms: 1700023E05Rik, Thegl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71868
Homologene: 128474
Usb1
Name: U6 snRNA biogenesis 1
Synonyms: AA960436
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 101985
Homologene: 11611
Pth2r
Name: parathyroid hormone 2 receptor
Synonyms: Pthr2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213527
HGNC: HGNC:9609
Homologene: 3701
Gal3st1
Name: galactose-3-O-sulfotransferase 1
Synonyms: GalCer sulfotransferase, Gcst, galactosylceramide sulfotransferase, Cst, 3'-phosphoadenylylsulfate-galactosylceramide 3'-sulfotransferase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53897
Homologene: 3574
Pcare
Name: photoreceptor cilium actin regulator
Synonyms: BC027072
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225004
VEGA: 17
Homologene: 19792
Ccdc162
Name: coiled-coil domain containing 162
Synonyms: 5033413D22Rik, Gm6976, Gm29096
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75973
Homologene: 136355
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404238
Homologene: 138632
Slc30a8
Name: solute carrier family 30 (zinc transporter), member 8
Synonyms: ZnT-8, ZnT8, C820002P14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239436
Homologene: 13795
Vps25
Name: vacuolar protein sorting 25
Synonyms: D11Wsu68e, 1110020N13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 28084
Homologene: 6303
Adamtsl2
Name: ADAMTS-like 2
Synonyms: stb, A930008K15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77794
Homologene: 8798
Entrep2
Name: endosomal transmembrane epsin interactor 2
Synonyms: 5730507A09Rik, Fam189a1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70638
Homologene: 77705
Cyp4f37
Name: cytochrome P450, family 4, subfamily f, polypeptide 37
Synonyms: Gm9705
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 677156
VEGA: 17
Homologene: 135840
Sult1c2
Name: sulfotransferase family, cytosolic, 1C, member 2
Synonyms: ST1C1, 1810008N17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69083
Homologene: 38201
Pigq
Name: phosphatidylinositol glycan anchor biosynthesis, class Q
Synonyms: Gpi1p, Gpi1, Gpi1h, Gpih
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14755
Homologene: 31228
Celf3
Name: CUGBP, Elav-like family member 3
Synonyms: ERDA4, Tnrc4, BRUNOL1, CAGH4, 4930415M08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 78784
Homologene: 48510
Or4c3d
Name: olfactory receptor family 4 subfamily C member 3D
Synonyms: MOR235-1, Olfr140, GA_x6K02T2Q125-51484508-51483600, A16
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57272
Homologene: 41379
Ankrd63
Name: ankyrin repeat domain 63
Synonyms: LOC383787, Gm1337
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 383787
Homologene: 19774
Ska1
Name: spindle and kinetochore associated complex subunit 1
Synonyms: 2810433K01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66468
VEGA: 18
Homologene: 11975
Zfp92
Name: zinc finger protein 92
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 22754
Homologene: 69050
Adam1a
Name: a disintegrin and metallopeptidase domain 1a
Synonyms: PH-30 alpha, Ftna, fertilin alpha
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 280668
HGNC: HGNC:187
Homologene: 73803
L1cam
Name: L1 cell adhesion molecule
Synonyms: CD171, L1, L1-NCAM, NCAM-L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 16728
HGNC: HGNC:6470
Homologene: 20128
AL732466.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Gm10650
Name: predicted gene 10650
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Pdk3
Name: pyruvate dehydrogenase kinase, isoenzyme 3
Synonyms: 2610001M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 236900
HGNC: HGNC:8811
Homologene: 55897
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 51,797,375 bp
  • G to T, chromosome 1 at 65,336,769 bp
  • T to A, chromosome 1 at 87,929,742 bp
  • A to G, chromosome 1 at 173,183,615 bp
  • C to A, chromosome 2 at 12,404,045 bp
  • A to T, chromosome 2 at 24,863,215 bp
  • G to A, chromosome 2 at 27,103,178 bp
  • A to G, chromosome 2 at 31,018,738 bp
  • T to A, chromosome 2 at 59,311,686 bp
  • A to T, chromosome 2 at 76,944,153 bp
  • A to T, chromosome 2 at 90,052,225 bp
  • A to G, chromosome 2 at 118,703,365 bp
  • T to C, chromosome 2 at 125,670,256 bp
  • A to G, chromosome 2 at 150,950,050 bp
  • G to T, chromosome 2 at 154,058,328 bp
  • A to G, chromosome 2 at 156,017,816 bp
  • T to A, chromosome 3 at 87,978,931 bp
  • T to C, chromosome 3 at 94,434,539 bp
  • T to A, chromosome 3 at 94,480,259 bp
  • A to G, chromosome 3 at 128,039,763 bp
  • A to G, chromosome 3 at 138,466,379 bp
  • G to A, chromosome 5 at 4,046,603 bp
  • A to G, chromosome 5 at 77,059,405 bp
  • A to C, chromosome 5 at 121,519,732 bp
  • C to T, chromosome 5 at 150,438,708 bp
  • A to G, chromosome 6 at 7,689,316 bp
  • A to G, chromosome 6 at 48,448,672 bp
  • T to C, chromosome 6 at 55,385,459 bp
  • T to C, chromosome 6 at 83,369,471 bp
  • T to C, chromosome 6 at 113,464,800 bp
  • A to G, chromosome 7 at 12,771,751 bp
  • T to C, chromosome 7 at 48,643,022 bp
  • G to A, chromosome 7 at 64,759,222 bp
  • T to C, chromosome 7 at 109,557,207 bp
  • C to T, chromosome 7 at 114,226,933 bp
  • A to G, chromosome 8 at 13,063,356 bp
  • T to A, chromosome 8 at 36,512,553 bp
  • T to G, chromosome 8 at 95,344,046 bp
  • C to T, chromosome 9 at 21,279,546 bp
  • CACACACACACACACACACACACACACACACA to CACACACACACACACACACACACACACACACACA, chromosome 10 at 41,539,381 bp
  • T to C, chromosome 11 at 3,998,282 bp
  • G to A, chromosome 11 at 17,193,115 bp
  • C to T, chromosome 11 at 96,955,936 bp
  • C to T, chromosome 11 at 100,503,152 bp
  • T to A, chromosome 11 at 101,257,888 bp
  • T to A, chromosome 12 at 40,068,931 bp
  • C to T, chromosome 12 at 65,044,012 bp
  • A to C, chromosome 12 at 81,315,220 bp
  • A to G, chromosome 12 at 104,392,800 bp
  • G to A, chromosome 12 at 113,063,367 bp
  • T to C, chromosome 13 at 33,925,320 bp
  • T to C, chromosome 13 at 98,271,138 bp
  • A to T, chromosome 14 at 56,027,988 bp
  • A to T, chromosome 14 at 74,645,029 bp
  • G to A, chromosome 15 at 28,408,417 bp
  • G to T, chromosome 15 at 52,306,564 bp
  • T to A, chromosome 15 at 79,615,381 bp
  • T to C, chromosome 15 at 84,702,780 bp
  • G to A, chromosome 15 at 90,985,362 bp
  • A to G, chromosome 15 at 91,764,716 bp
  • A to G, chromosome 15 at 98,524,478 bp
  • G to A, chromosome 16 at 38,332,364 bp
  • T to C, chromosome 16 at 94,459,972 bp
  • T to C, chromosome 17 at 25,932,209 bp
  • A to G, chromosome 17 at 32,634,270 bp
  • C to T, chromosome 17 at 42,666,898 bp
  • G to T, chromosome 17 at 53,831,820 bp
  • T to C, chromosome 17 at 57,193,876 bp
  • A to G, chromosome 17 at 71,749,284 bp
  • T to A, chromosome 18 at 5,046,640 bp
  • G to T, chromosome 18 at 74,197,066 bp
  • G to T, chromosome X at 73,422,752 bp
  • T to A, chromosome X at 73,861,341 bp
  • G to T, chromosome X at 93,813,998 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2232 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040233-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.