Strain Name:
C57BL/6J-MtgxR2275Btlr/Mmmh
Stock Number:
040274-MU
Citation ID:
RRID:MMRRC_040274-MU
Other Names:
R2275 (G1), C57BL/6J-MtgxR2275Btlr
Major Collection:

Gene Information

Tyrp1
Name: tyrosinase-related protein 1
Synonyms: TRP-1, isa, Tyrp, TRP1, Oca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 22178
Homologene: 464
Arhgef7
Name: Rho guanine nucleotide exchange factor (GEF7)
Synonyms: cool-1, Pak interacting exchange factor, betaPix, p85SPR, PIX, Cool, betaPix-c, betaPix-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 54126
Homologene: 2895
Rptor
Name: regulatory associated protein of MTOR, complex 1
Synonyms: raptor, Rap, 4932417H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74370
Homologene: 80210
Fn1
Name: fibronectin 1
Synonyms: Fn-1, Fn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: Tkrb, C030027L06Rik, trkB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18212
VEGA: 13
HGNC: HGNC:8032
Homologene: 4504
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Aco2
Name: aconitase 2, mitochondrial
Synonyms: Aco3, D10Wsu183e, Aco-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 11429
HGNC: HGNC:118
Homologene: 856
Cdr2
Name: cerebellar degeneration-related 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12585
HGNC: HGNC:1799
Homologene: 7262
Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Synonyms: Autotaxin, ATX, PD-Ialpha, Npps2, Pdnp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18606
HGNC: HGNC:3357
Homologene: 4526
Usp1
Name: ubiquitin specific peptidase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230484
Homologene: 2528
Kifap3
Name: kinesin-associated protein 3
Synonyms: KAP3, Smg GDS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16579
Homologene: 7799
Pibf1
Name: progesterone immunomodulatory binding factor 1
Synonyms: 4933438D16Rik, 4930513H15Rik, D14Ertd581e, 1700017E21Rik, 4933439E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 52023
VEGA: 14
Homologene: 4628
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Knl1
Name: kinetochore scaffold 1
Synonyms: 5730505K17Rik, 2310043D08Rik, Casc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76464
Homologene: 44890
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2900036C23Rik, 6030449K19Rik, 2410152H17Rik, 2810413I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66315
Homologene: 10778
Nav2
Name: neuron navigator 2
Synonyms: RAINB2, HELAD1, Unc53H2, 5330421F07Rik, POMFIL2, Rainb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78286
Homologene: 52330
Csad
Name: cysteine sulfinic acid decarboxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 246277
VEGA: 15
Homologene: 41086
Parg
Name: poly (ADP-ribose) glycohydrolase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 26430
HGNC: HGNC:8605
Homologene: 50532
Slc12a3
Name: solute carrier family 12, member 3
Synonyms: TSC, NCC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20497
Homologene: 287
Ehmt2
Name: euchromatic histone lysine N-methyltransferase 2
Synonyms: G9a, NG36, D17Ertd710e, Bat8, KMT1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 110147
Homologene: 48460
Ackr1
Name: atypical chemokine receptor 1 (Duffy blood group)
Synonyms: Dfy, CD234, Darc, CCBP1, ESTM35, FY
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13349
HGNC: HGNC:4035
Homologene: 48067
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Tsr1
Name: TSR1 20S rRNA accumulation
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 104662
Homologene: 5576
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: Gtl4, cat eye syndrome chromosome region, candidate 2, 2610101O16Rik, 2810409N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: Zfp650, 1110059H15Rik, 4833421P10Rik, A130030D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68795
Homologene: 52092
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Glg1
Name: golgi apparatus protein 1
Synonyms: ESL-1, CFR, MG160, CFR-1, Selel, MG-160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Tia1
Name: cytotoxic granule-associated RNA binding protein 1
Synonyms: 2310050N03Rik, mTIA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 21841
Homologene: 20692
C87436
Name: expressed sequence C87436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232196
Homologene: 9897
Zdhhc11
Name: zinc finger, DHHC domain containing 11
Synonyms: 4933421L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 71164
VEGA: 13
Homologene: 128723
Col9a2
Name: collagen, type IX, alpha 2
Synonyms: Col9a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12840
HGNC: HGNC:2218
Homologene: 37535
Map4k1
Name: mitogen-activated protein kinase kinase kinase kinase 1
Synonyms: Hpk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26411
HGNC: HGNC:6863
Homologene: 5199
Adamtsl3
Name: ADAMTS-like 3
Synonyms: punctin-2, 9230119C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269959
Homologene: 18912
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100213
Homologene: 18967
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
Synonyms: 2310015G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69547
Homologene: 18876
Slc4a8
Name: solute carrier family 4 (anion exchanger), member 8
Synonyms: sodium bicarbonate cotransporter isoform 3 kNBC-3, KNBC-3, NDCBE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 59033
Homologene: 68419
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 192188
Homologene: 23022
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 100125586
Homologene: 129753
Atxn7
Name: ataxin 7
Synonyms: Sca7, A430107N12Rik, ataxin-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 246103
VEGA: 14
Homologene: 30967
Farp2
Name: FERM, RhoGEF and pleckstrin domain protein 2
Synonyms: Fir, D030026M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227377
Homologene: 8877
Serpinb6d
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6d
Synonyms: Gm11390, SPI3D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238568
HGNC: HGNC:8950
Exoc3l
Name: exocyst complex component 3-like
Synonyms: C730015A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 277978
Homologene: 18629
Armc4
Name: armadillo repeat containing 4
Synonyms: b2b643Clo, 4930463I21Rik, b2b227.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74934
VEGA: 18
Homologene: 9992
Gpatch1
Name: G patch domain containing 1
Synonyms: 1300003A17Rik, Gpatc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67471
Homologene: 41217
Gpr158
Name: G protein-coupled receptor 158
Synonyms: 5330427M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241263
Homologene: 19381
Cdh4
Name: cadherin 4
Synonyms: R-cadherin, R-Cadh, Rcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12561
HGNC: HGNC:1763
Homologene: 48044
Vmn1r228
Name: vomeronasal 1 receptor 228
Synonyms: V1re3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171226
Homologene: 74320
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Mypn
Name: myopalladin
Synonyms: 1110056A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 68802
VEGA: 10
Homologene: 23778
Dnlz
Name: DNL-type zinc finger
Synonyms: D2Bwg1335e, 1110034G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 52838
Homologene: 36864
Emilin1
Name: elastin microfibril interfacer 1
Synonyms: gp115, EMILIN-1, 5830419M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100952
Homologene: 5117
Pla2g4b
Name: phospholipase A2, group IVB (cytosolic)
Synonyms: A030011C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 211429
HGNC: HGNC:9036
Homologene: 3730
Olfr1170
Name: olfactory receptor 1170
Synonyms: MOR174-12, GA_x6K02T2Q125-49709783-49708833
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258525
Homologene: 138307
F11
Name: coagulation factor XI
Synonyms: plasma thromboplastin antecedent, Cf11, 1600027G01Rik, FXI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: ether a go-go, Kv10.1, Eag1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Pde7b
Name: phosphodiesterase 7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 29863
HGNC: HGNC:8792
Homologene: 32194
Slc46a1
Name: solute carrier family 46, member 1
Synonyms: 1110002C08Rik, heme carrier protein 1, D11Ertd18e, PCFT, HCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 52466
Homologene: 41693
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: Snep, D430044C15Rik, 6720455I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 208777
Homologene: 14708
Vmn2r60
Name: vomeronasal 2, receptor 60
Synonyms: Casr-rs3, EG637898, Gprc2a-rs3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 637898
Homologene: 129683
March1
Name: membrane-associated ring finger (C3HC4) 1
Synonyms: 2900024D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72925
Homologene: 113749
Gm6434
Name: predicted gene 6434
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101055953
Gm11568
Name: predicted gene 11568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 432600
Ppp1r26
Name: protein phosphatase 1, regulatory subunit 26
Synonyms: LOC241289
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241289
Homologene: 49400
Zbtb7a
Name: zinc finger and BTB domain containing 7a
Synonyms: Zbtb7, Leukemia/lymphoma Related Factor, 9030619K07Rik, 9130006G12Rik, Pokemon, FBI-1, Lrf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16969
Homologene: 7820
Iqck
Name: IQ motif containing K
Synonyms: A230094G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434232
Homologene: 45162
Hecw1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Synonyms: E130207I19Rik, NEDL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 94253
VEGA: 13
Homologene: 9004
4921506M07Rik
Name: RIKEN cDNA 4921506M07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
4930423O20Rik
Name: RIKEN cDNA 4930423O20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
Vmn1r232
Name: vomeronasal 1 receptor 232
Synonyms: V1re4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 171227
Homologene: 121611
2300003K06Rik
Name: RIKEN cDNA 2300003K06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 100502865
1700013F07Rik
Name: RIKEN cDNA 1700013F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75504
Homologene: 18986
AC159899.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Slco4a1
Name: solute carrier organic anion transporter family, member 4a1
Synonyms: Slc21a12, OATP-E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 108115
Homologene: 9482
Nt5c1a
Name: 5'-nucleotidase, cytosolic IA
Synonyms: Cn1a, LOC230718
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230718
Homologene: 57173
Crygs
Name: crystallin, gamma S
Synonyms: Opj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12970
VEGA: 16
HGNC: HGNC:2417
Homologene: 40695
Hoxd1
Name: homeobox D1
Synonyms: Hox-4.9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15429
HGNC: HGNC:5132
Homologene: 7772
Nrarp
Name: Notch-regulated ankyrin repeat protein
Synonyms: 2700054M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67122
Homologene: 32649
Gm14459
Name: predicted gene 14459
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 546263
Homologene: 85956
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 20,200,849 bp
  • C to T, chromosome 1 at 71,613,943 bp
  • T to A, chromosome 1 at 93,281,642 bp
  • A to T, chromosome 1 at 93,528,789 bp
  • G to T, chromosome 1 at 130,846,470 bp
  • T to A, chromosome 1 at 163,868,758 bp
  • T to C, chromosome 1 at 173,332,485 bp
  • T to G, chromosome 1 at 192,337,521 bp
  • A to T, chromosome 2 at 21,826,863 bp
  • T to C, chromosome 2 at 25,181,409 bp
  • A to T, chromosome 2 at 26,351,471 bp
  • A to G, chromosome 2 at 28,452,701 bp
  • GTGGCT to GT, chromosome 2 at 29,154,061 bp
  • T to C, chromosome 2 at 70,016,341 bp
  • A to G, chromosome 2 at 74,764,157 bp
  • A to G, chromosome 2 at 88,224,823 bp
  • C to A, chromosome 2 at 119,072,281 bp
  • A to C, chromosome 2 at 120,036,829 bp
  • T to C, chromosome 2 at 179,890,847 bp
  • T to C, chromosome 2 at 180,464,736 bp
  • T to C, chromosome 3 at 64,116,509 bp
  • A to G, chromosome 3 at 108,542,503 bp
  • G to A, chromosome 4 at 43,416,260 bp
  • A to T, chromosome 4 at 80,837,534 bp
  • T to C, chromosome 4 at 98,929,842 bp
  • C to G, chromosome 4 at 121,054,258 bp
  • T to C, chromosome 4 at 123,216,080 bp
  • G to A, chromosome 4 at 130,006,854 bp
  • C to T, chromosome 5 at 30,917,738 bp
  • A to G, chromosome 6 at 86,427,677 bp
  • G to A, chromosome 6 at 86,445,600 bp
  • C to T, chromosome 6 at 120,756,741 bp
  • A to G, chromosome 7 at 19,523,897 bp
  • G to T, chromosome 7 at 25,882,108 bp
  • T to A, chromosome 7 at 29,001,957 bp
  • A to T, chromosome 7 at 35,288,678 bp
  • T to A, chromosome 7 at 42,136,827 bp
  • T to A, chromosome 7 at 49,491,499 bp
  • A to T, chromosome 7 at 82,606,558 bp
  • G to A, chromosome 7 at 118,899,657 bp
  • A to T, chromosome 7 at 120,958,509 bp
  • T to A, chromosome 8 at 11,815,010 bp
  • T to C, chromosome 8 at 45,252,147 bp
  • T to A, chromosome 8 at 66,387,499 bp
  • T to A, chromosome 8 at 94,333,287 bp
  • A to T, chromosome 8 at 105,290,447 bp
  • A to T, chromosome 8 at 111,168,721 bp
  • A to T, chromosome 9 at 79,635,427 bp
  • T to C, chromosome 9 at 99,229,559 bp
  • T to A, chromosome 10 at 20,400,419 bp
  • A to G, chromosome 10 at 63,131,069 bp
  • G to A, chromosome 10 at 81,144,997 bp
  • A to T, chromosome 10 at 86,859,730 bp
  • A to T, chromosome 11 at 74,904,827 bp
  • T to G, chromosome 11 at 78,466,423 bp
  • T to A, chromosome 11 at 94,415,936 bp
  • A to T, chromosome 11 at 99,837,841 bp
  • A to G, chromosome 11 at 99,858,244 bp
  • A to T, chromosome 11 at 110,275,281 bp
  • T to A, chromosome 11 at 119,756,322 bp
  • G to A, chromosome 12 at 57,702,298 bp
  • T to C, chromosome 13 at 14,346,068 bp
  • A to T, chromosome 13 at 33,671,428 bp
  • T to A, chromosome 13 at 58,861,351 bp
  • C to A, chromosome 13 at 73,973,752 bp
  • T to A, chromosome 14 at 14,013,268 bp
  • A to G, chromosome 14 at 32,295,238 bp
  • A to T, chromosome 14 at 99,107,511 bp
  • A to C, chromosome 15 at 54,897,794 bp
  • C to T, chromosome 15 at 81,895,264 bp
  • A to G, chromosome 15 at 100,807,402 bp
  • G to T, chromosome 15 at 102,187,122 bp
  • T to C, chromosome 16 at 5,094,552 bp
  • C to T, chromosome 16 at 22,805,551 bp
  • T to C, chromosome 16 at 56,184,783 bp
  • T to G, chromosome 16 at 70,381,907 bp
  • A to G, chromosome 17 at 20,776,545 bp
  • A to G, chromosome 17 at 20,914,203 bp
  • T to A, chromosome 17 at 34,910,715 bp
  • C to A, chromosome 18 at 7,223,676 bp
  • C to A, chromosome X at 8,523,441 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2275 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040274-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.