Strain Name:
C57BL/6J-MtgxR2281Btlr/Mmmh
Stock Number:
040280-MU
Citation ID:
RRID:MMRRC_040280-MU
Other Names:
R2281 (G1), C57BL/6J-MtgxR2281Btlr
Major Collection:

Strain Information

Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: SCO1, Steel Factor Receptor, belly-spot, SCO5, Tr-kit, Dominant white spotting, Gsfsco1, SOW3, c-KIT, CD117, Gsfsco5, Gsfsow3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16590
HGNC: HGNC:6342
Homologene: 187
Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Synonyms: MCAD
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11364
HGNC: HGNC:89
Homologene: 3
Gsn
Name: gelsolin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227753
HGNC: HGNC:4620
Homologene: 147
Slc26a5
Name: solute carrier family 26, member 5
Synonyms: Pres, prestin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80979
HGNC: HGNC:9359
Homologene: 69472
Ece1
Name: endothelin converting enzyme 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230857
HGNC: HGNC:3146
Homologene: 1068
Mga
Name: MAX gene associated
Synonyms: Mad5, D030062C11Rik, Mga, C130042M01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 29808
Homologene: 49351
Smyd1
Name: SET and MYND domain containing 1
Synonyms: 4632404M21Rik, Bop
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12180
Homologene: 7645
Fryl
Name: FRY like transcription coactivator
Synonyms: 9030227G01Rik, 2310004H21Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: Prkwnk1, 6430573H23Rik, EG406236, Hsn2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232341
Homologene: 14253
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: mechanistic target of rapamycin (serine/threonine kinase), Frap1, RAFT1, 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, flat, RAPT1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: NF-kappaB, NF-kappaB p50, p50, nuclear factor kappaB p50, p50/p105, NF kappaB1, p50 subunit of NF kappaB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18033
HGNC: HGNC:7794
Homologene: 2971
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328977
Homologene: 138627
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: D3Ertd775e, Lba
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Glod4
Name: glyoxalase domain containing 4
Synonyms: 2700085E05Rik, 1700082G03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67201
Homologene: 9376
Ube4b
Name: ubiquitination factor E4B
Synonyms: D4Bwg0973e, 4933406G05Rik, 4930551I19Rik, UFD2a, Ufd2p, UFD2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 63958
Homologene: 107623
Mreg
Name: melanoregulin
Synonyms: Wdt2, LOC381269, dsu
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381269
Homologene: 9954
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: 5730509K17Rik, b2b1035Clo
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231214
Homologene: 18159
Atg13
Name: autophagy related 13
Synonyms: 1110053A20Rik, D2Ertd391e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51897
Homologene: 32229
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: Bolvr, mBLVR1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Ptprj
Name: protein tyrosine phosphatase receptor type J
Synonyms: RPTPJ, CD148, DEP-1, Scc1, Byp, Scc-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: JHDM2B, 5830462I21Rik, Jmjd1b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Ganab
Name: alpha glucosidase 2 alpha neutral subunit
Synonyms: G2an, GluII
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14376
VEGA: 19
HGNC: HGNC:4138
Homologene: 5426
H1f2
Name: H1.2 linker histone, cluster member
Synonyms: Hist1h1c, H1f2, H1c, H1var1, 0610008C09Rik, H1.2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 50708
HGNC: HGNC:4716
Homologene: 68455
Nlrp3
Name: NLR family, pyrin domain containing 3
Synonyms: Cias1, Mmig1, NALP3, cryopyrin, Pypaf1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216799
Homologene: 3600
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, Tem5-like, 3830613O22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70693
Homologene: 19235
Lsr
Name: lipolysis stimulated lipoprotein receptor
Synonyms: Lisch7, ILDR3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54135
Homologene: 9306
Egln1
Name: egl-9 family hypoxia-inducible factor 1
Synonyms: SM-20, ORF13, Hif-p4h-2, Phd2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 112405
HGNC: HGNC:1232
Homologene: 56936
Tinagl1
Name: tubulointerstitial nephritis antigen-like 1
Synonyms: Lcn7, AZ-1, 1110021J17Rik, Arg1, androgen-regulated gene 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 94242
Homologene: 41472
Tmem231
Name: transmembrane protein 231
Synonyms: 4932417I16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234740
Homologene: 78035
Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Synonyms: HZF-3, RNR-1, Nurr1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18227
HGNC: HGNC:7981
Homologene: 4509
Ptger2
Name: prostaglandin E receptor 2 (subtype EP2)
Synonyms: EP2, Ptgerep2, EP2 receptor
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19217
HGNC: HGNC:9594
Homologene: 739
Stag3
Name: STAG3 cohesin complex component
Synonyms: stromalin 3, SA-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50878
Homologene: 40844
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: ALDH1, E1, Ahd2, Raldh1, Ahd-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Abca3
Name: ATP-binding cassette, sub-family A member 3
Synonyms: Abc3, ABC-C, 1810036E22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Mboat4
Name: membrane bound O-acyltransferase domain containing 4
Synonyms: GOAT, LOC234155
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234155
Homologene: 19272
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: mineralocorticoid receptor, Mlr, aldosterone receptor, MR
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif 4
Synonyms: aggrecanase-1, ADAM-TS4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240913
HGNC: HGNC:220
Homologene: 36169
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226652
Homologene: 18766
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Txnip
Name: thioredoxin interacting protein
Synonyms: mVDUP1, THIF, Hyplip1, VDUP1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56338
Homologene: 38186
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, Polydom, D430029O09Rik, 4833413O10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64817
Homologene: 23386
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 279499
Homologene: 18630
Sntg1
Name: syntrophin, gamma 1
Synonyms: SYN4, G1SYN
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71096
Homologene: 56834
Cdh5
Name: cadherin 5
Synonyms: CD144, VECD, VEC, 7B4/cadherin-5, VE-cadherin, VEcad, VE-Cad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Stk31
Name: serine threonine kinase 31
Synonyms: C330007K24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 77485
Homologene: 12677
Ccser1
Name: coiled-coil serine rich 1
Synonyms: C130092O11Rik, 6230405M12Rik, Fam190a
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232035
Homologene: 28086
Hrg
Name: histidine-rich glycoprotein
Synonyms: D16JH2, D18020
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Ccdc168
Name: coiled-coil domain containing 168
Synonyms: Gm8251
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102636082
VEGA: 1
Homologene: 141149
Or4c109
Name: olfactory receptor family 4 subfamily C member 109
Synonyms: MOR233-8, Olfr1214, GA_x6K02T2Q125-50468705-50467770
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258899
Homologene: 73984
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Ecsit
Name: ECSIT signalling integrator
Synonyms: Sitpec
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26940
Homologene: 8080
Dcaf11
Name: DDB1 and CUL4 associated factor 11
Synonyms: GLO14, D14Ucla1, 0710008A13Rik, Wdr23
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 28199
Homologene: 11886
Zc3h7a
Name: zinc finger CCCH type containing 7 A
Synonyms: A430104C18Rik, Zc3h7
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106205
Homologene: 8563
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66605
Homologene: 45135
Dhx58
Name: DExH-box helicase 58
Synonyms: D11Lgp2e, B430001I08Rik, LPG2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80861
Homologene: 69371
Flnc
Name: filamin C, gamma
Synonyms: 1110055E19Rik, actin binding protein 280, Fln2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Plch2
Name: phospholipase C, eta 2
Synonyms: A930027K05Rik, PLCeta2, Plcl4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269615
Homologene: 85172
Caskin2
Name: CASK-interacting protein 2
Synonyms: 1600028L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 140721
Homologene: 32485
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: 4933417L02Rik, Ikbn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73845
Homologene: 23652
Tmem216
Name: transmembrane protein 216
Synonyms: 4921533J23Rik, A930021F15Rik, 1110017C22Rik, 2810441K11Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 68642
Homologene: 9541
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mouse
Chromosome: 3
Homologene: 41344
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Spmap2l
Name: sperm microtubule associated protein 2 like
Synonyms: 1700023E05Rik, Thegl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71868
Homologene: 128474
Ric8a
Name: RIC8 guanine nucleotide exchange factor A
Synonyms: RIC-8, synembryn, Ric8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101489
Homologene: 23331
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: nmf192, 4930564O18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 260305
Homologene: 9024
Ptpru
Name: protein tyrosine phosphatase receptor type U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Ano3
Name: anoctamin 3
Synonyms: Tmem16c, B230324K02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228432
Homologene: 57147
Or2y1f
Name: olfactory receptor family 2 subfamily Y member 1F
Synonyms: GA_x6K02T2QP88-6141322-6140387, MOR256-25, Olfr1392
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258462
Homologene: 81347
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Gabrg2
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2
Synonyms: gamma2, GABAA-R, Gabrg-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14406
HGNC: HGNC:4087
Homologene: 22443
Cma2
Name: chymase 2, mast cell
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545055
VEGA: 14
Homologene: 115745
Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Synonyms: 1alpha(OH)ase, P450c1, Cyp40, Cyp27b, 25(OH)D 1alpha-hydroxylase, Vddr, 25-hydroxyvitamin D3 1alpha-hydroxylase, Cp2b, P450VD1alpha, VddrI, Pddr, Vdd1, Cyp1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13115
HGNC: HGNC:2606
Homologene: 37139
Dlg2
Name: discs large MAGUK scaffold protein 2
Synonyms: B230218P12Rik, A330103J02Rik, LOC382816, B330007M19Rik, Chapsyn-110, PSD93, Dlgh2, Gm21505
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23859
HGNC: HGNC:2901
Homologene: 1046
Methig1
Name: methyltransferase hypoxia inducible domain containing 1
Synonyms: Mettl7a2-Higd1c, UbiE-YGHL1, Mettl7a2Higd1c, UbiE2-Hig1-4, AB099516
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 554292
Homologene: 128515
Ajuba
Name: ajuba LIM protein
Synonyms: Jub
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16475
VEGA: 14
Homologene: 7789
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: PML, 0610012C17Rik, 1110006M24Rik, phospholemman, PLM
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Crtac1
Name: cartilage acidic protein 1
Synonyms: 2810454P21Rik, Lotus, Crtac1B
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72832
VEGA: 19
Homologene: 23070
Mlf1
Name: myeloid leukemia factor 1
Synonyms: HLS7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 17349
HGNC: HGNC:7125
Homologene: 7839
Fam43b
Name: family with sequence similarity 43, member B
Synonyms: OTTMUSG00000009974
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 625638
Homologene: 45810
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 8,595,402 bp
  • T to A, chromosome 1 at 44,056,460 bp
  • A to T, chromosome 1 at 72,192,064 bp
  • A to G, chromosome 1 at 164,195,720 bp
  • A to T, chromosome 1 at 171,256,229 bp
  • A to G, chromosome 1 at 171,389,328 bp
  • T to A, chromosome 2 at 35,283,918 bp
  • T to A, chromosome 2 at 57,112,199 bp
  • G to A, chromosome 2 at 88,987,470 bp
  • T to A, chromosome 2 at 90,471,341 bp
  • T to C, chromosome 2 at 91,679,425 bp
  • T to A, chromosome 2 at 110,682,759 bp
  • A to G, chromosome 2 at 119,903,723 bp
  • G to A, chromosome 3 at 67,399,751 bp
  • A to G, chromosome 3 at 86,776,103 bp
  • C to G, chromosome 3 at 96,559,447 bp
  • T to C, chromosome 3 at 135,601,521 bp
  • A to G, chromosome 3 at 146,646,424 bp
  • A to G, chromosome 3 at 153,933,043 bp
  • G to T, chromosome 4 at 58,082,677 bp
  • A to G, chromosome 4 at 130,166,993 bp
  • C to A, chromosome 4 at 131,808,499 bp
  • C to T, chromosome 4 at 137,946,362 bp
  • G to C, chromosome 4 at 138,395,098 bp
  • A to G, chromosome 4 at 148,489,555 bp
  • A to G, chromosome 4 at 149,344,572 bp
  • T to C, chromosome 4 at 152,135,545 bp
  • A to G, chromosome 4 at 152,557,043 bp
  • A to T, chromosome 4 at 154,984,309 bp
  • A to G, chromosome 5 at 14,540,332 bp
  • A to G, chromosome 5 at 21,831,510 bp
  • C to T, chromosome 5 at 43,737,481 bp
  • C to T, chromosome 5 at 50,001,880 bp
  • T to C, chromosome 5 at 73,041,364 bp
  • T to C, chromosome 5 at 75,637,283 bp
  • T to C, chromosome 5 at 77,059,367 bp
  • T to C, chromosome 5 at 138,298,284 bp
  • G to A, chromosome 6 at 29,438,666 bp
  • T to C, chromosome 6 at 48,458,096 bp
  • C to T, chromosome 6 at 49,417,250 bp
  • A to T, chromosome 6 at 61,570,815 bp
  • T to C, chromosome 6 at 71,238,676 bp
  • A to T, chromosome 6 at 119,963,640 bp
  • C to T, chromosome 7 at 30,958,345 bp
  • G to A, chromosome 7 at 31,053,878 bp
  • T to A, chromosome 7 at 92,438,041 bp
  • G to A, chromosome 7 at 92,625,773 bp
  • A to G, chromosome 7 at 140,861,938 bp
  • T to A, chromosome 8 at 34,115,223 bp
  • C to A, chromosome 8 at 76,909,907 bp
  • A to G, chromosome 8 at 104,125,733 bp
  • T to C, chromosome 8 at 105,387,266 bp
  • T to C, chromosome 8 at 111,918,931 bp
  • T to C, chromosome 8 at 124,948,414 bp
  • C to T, chromosome 9 at 22,076,540 bp
  • T to C, chromosome 10 at 80,713,998 bp
  • T to A, chromosome 10 at 100,603,338 bp
  • T to G, chromosome 10 at 127,048,294 bp
  • A to T, chromosome 11 at 9,328,136 bp
  • T to C, chromosome 11 at 41,976,636 bp
  • A to C, chromosome 11 at 49,293,632 bp
  • T to C, chromosome 11 at 59,549,136 bp
  • A to T, chromosome 11 at 76,237,809 bp
  • T to C, chromosome 11 at 76,797,801 bp
  • A to G, chromosome 11 at 100,698,154 bp
  • G to T, chromosome 11 at 115,802,989 bp
  • A to G, chromosome 12 at 8,978,628 bp
  • A to G, chromosome 13 at 23,738,924 bp
  • G to T, chromosome 14 at 44,989,650 bp
  • C to A, chromosome 14 at 54,577,188 bp
  • G to T, chromosome 14 at 55,569,371 bp
  • T to A, chromosome 14 at 55,971,528 bp
  • T to A, chromosome 14 at 79,064,996 bp
  • A to T, chromosome 15 at 100,353,360 bp
  • T to C, chromosome 16 at 11,158,594 bp
  • C to T, chromosome 16 at 22,961,309 bp
  • T to A, chromosome 17 at 24,376,726 bp
  • A to G, chromosome 18 at 34,808,419 bp
  • T to C, chromosome 18 at 61,262,434 bp
  • T to C, chromosome 18 at 65,624,712 bp
  • T to C, chromosome 19 at 8,909,468 bp
  • T to A, chromosome 19 at 10,551,873 bp
  • A to G, chromosome 19 at 20,620,091 bp
  • T to A, chromosome 19 at 24,378,947 bp
  • G to A, chromosome 19 at 42,283,567 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2281 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040280-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.