Strain Name:
C57BL/6J-MtgxR2281Btlr/Mmmh
Stock Number:
040280-MU
Citation ID:
RRID:MMRRC_040280-MU
Other Names:
R2281 (G1), C57BL/6J-MtgxR2281Btlr
Major Collection:

Gene Information

Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Synonyms: CD117, Dominant white spotting, Tr-kit, Gsfsco1, Gsfsco5, Gsfsow3, SOW3, SCO5, SCO1, c-KIT, Steel Factor Receptor, belly-spot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16590
HGNC: HGNC:6342
Homologene: 187
Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Synonyms: MCAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11364
HGNC: HGNC:89
Homologene: 3
Gsn
Name: gelsolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227753
HGNC: HGNC:4620
Homologene: 147
Slc26a5
Name: solute carrier family 26, member 5
Synonyms: prestin, Pres
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 80979
HGNC: HGNC:9359
Homologene: 69472
Ece1
Name: endothelin converting enzyme 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230857
HGNC: HGNC:3146
Homologene: 1068
Mga
Name: MAX gene associated
Synonyms: Mga, Mad5, C130042M01Rik, D030062C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 29808
Homologene: 49351
Smyd1
Name: SET and MYND domain containing 1
Synonyms: 4632404M21Rik, Bop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12180
Homologene: 7645
Fryl
Name: FRY like transcription coactivator
Synonyms: 2510002A14Rik, 2310004H21Rik, 9030227G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72313
Homologene: 103956
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: EG406236, Hsn2, 6430573H23Rik, Prkwnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232341
Homologene: 14253
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, Frap1, RAPT1, RAFT1, mechanistic target of rapamycin (serine/threonine kinase), flat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Synonyms: nuclear factor kappaB p50, NF-kappaB p50, p50/p105, p50, NF-kappaB, NF kappaB1, p50 subunit of NF kappaB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18033
HGNC: HGNC:7794
Homologene: 2971
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328977
Homologene: 138627
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: D3Ertd775e, Lba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Glod4
Name: glyoxalase domain containing 4
Synonyms: 1700082G03Rik, 2700085E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 67201
Homologene: 9376
Ube4b
Name: ubiquitination factor E4B
Synonyms: 4930551I19Rik, Ufd2p, D4Bwg0973e, UFD2a, UFD2, 4933406G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 63958
Homologene: 107623
Mreg
Name: melanoregulin
Synonyms: dsu, LOC381269, Wdt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381269
Homologene: 9954
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: b2b1035Clo, 5730509K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231214
Homologene: 18159
Atg13
Name: autophagy related 13
Synonyms: 1110053A20Rik, D2Ertd391e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51897
Homologene: 32229
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: Byp, CD148, DEP-1, RPTPJ, Scc-1, Scc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: Jmjd1b, 5830462I21Rik, JHDM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Ganab
Name: alpha glucosidase 2 alpha neutral subunit
Synonyms: G2an, GluII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 14376
VEGA: 19
HGNC: HGNC:4138
Homologene: 5426
Hist1h1c
Name: histone cluster 1, H1c
Synonyms: H1c, 0610008C09Rik, H1f2, H1.2, H1var1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 50708
HGNC: HGNC:4716
Homologene: 68455
Nlrp3
Name: NLR family, pyrin domain containing 3
Synonyms: cryopyrin, Mmig1, NALP3, Cias1, Pypaf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216799
Homologene: 3600
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Lsr
Name: lipolysis stimulated lipoprotein receptor
Synonyms: Lisch7, ILDR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54135
Homologene: 9306
Egln1
Name: egl-9 family hypoxia-inducible factor 1
Synonyms: Hif-p4h-2, Phd2, ORF13, SM-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 112405
HGNC: HGNC:1232
Homologene: 56936
Tinagl1
Name: tubulointerstitial nephritis antigen-like 1
Synonyms: Arg1, androgen-regulated gene 1, Lcn7, 1110021J17Rik, AZ-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 94242
Homologene: 41472
Tmem231
Name: transmembrane protein 231
Synonyms: 4932417I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234740
Homologene: 78035
Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Synonyms: Nurr1, RNR-1, HZF-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18227
HGNC: HGNC:7981
Homologene: 4509
Ptger2
Name: prostaglandin E receptor 2 (subtype EP2)
Synonyms: Ptgerep2, EP2 receptor, EP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19217
HGNC: HGNC:9594
Homologene: 739
Stag3
Name: stromal antigen 3
Synonyms: stromalin 3, SA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50878
Homologene: 40844
Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Synonyms: Ahd-2, ALDH1, Ahd2, Raldh1, E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 11668
HGNC: HGNC:402
Homologene: 110441
Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms: ABC-C, Abc3, 1810036E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27410
HGNC: HGNC:33
Homologene: 37437
Mboat4
Name: membrane bound O-acyltransferase domain containing 4
Synonyms: LOC234155, GOAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234155
Homologene: 19272
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268379
Homologene: 27991
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: Mlr, aldosterone receptor, mineralocorticoid receptor, MR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Adamts4
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Synonyms: ADAM-TS4, aggrecanase-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240913
HGNC: HGNC:220
Homologene: 36169
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226652
Homologene: 18766
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Txnip
Name: thioredoxin interacting protein
Synonyms: VDUP1, mVDUP1, THIF, Hyplip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 56338
Homologene: 38186
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, 4833413O10Rik, Polydom, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 64817
Homologene: 23386
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 279499
Homologene: 18630
Sntg1
Name: syntrophin, gamma 1
Synonyms: SYN4, G1SYN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71096
Homologene: 56834
Espn
Name: espin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56226
Homologene: 23164
Cdh5
Name: cadherin 5
Synonyms: VEC, CD144, VEcad, VE-cadherin, 7B4/cadherin-5, VE-Cad, VECD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Stk31
Name: serine threonine kinase 31
Synonyms: C330007K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 77485
Homologene: 12677
Ccser1
Name: coiled-coil serine rich 1
Synonyms: Fam190a, 6230405M12Rik, C130092O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232035
Homologene: 28086
Hrg
Name: histidine-rich glycoprotein
Synonyms: D16JH2, D18020
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 94175
HGNC: HGNC:5181
Homologene: 137650
Gm8251
Name: predicted gene 8251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 102636082
VEGA: 1
Homologene: 141149
Olfr1214
Name: olfactory receptor 1214
Synonyms: MOR233-8, GA_x6K02T2Q125-50468705-50467770
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258899
Homologene: 73984
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219189
VEGA: 14
Homologene: 44881
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
Ecsit
Name: ECSIT signalling integrator
Synonyms: Sitpec
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 26940
Homologene: 8080
Dcaf11
Name: DDB1 and CUL4 associated factor 11
Synonyms: D14Ucla1, GLO14, 0710008A13Rik, Wdr23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 28199
Homologene: 11886
Zc3h7a
Name: zinc finger CCCH type containing 7 A
Synonyms: Zc3h7, A430104C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 106205
Homologene: 8563
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243369
Homologene: 45453
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66605
Homologene: 45135
Dhx58
Name: DEXH (Asp-Glu-X-His) box polypeptide 58
Synonyms: B430001I08Rik, D11Lgp2e, LPG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 80861
Homologene: 69371
Flnc
Name: filamin C, gamma
Synonyms: actin binding protein 280, Fln2, 1110055E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Plch2
Name: phospholipase C, eta 2
Synonyms: A930027K05Rik, Plcl4, PLCeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269615
Homologene: 85172
Caskin2
Name: CASK-interacting protein 2
Synonyms: 1600028L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 140721
Homologene: 32485
Ankrd42
Name: ankyrin repeat domain 42
Synonyms: 4933417L02Rik, Ikbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73845
Homologene: 23652
Tmem216
Name: transmembrane protein 216
Synonyms: 4921533J23Rik, A930021F15Rik, 2810441K11Rik, 1110017C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 68642
Homologene: 9541
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75015
Homologene: 41344
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Thegl
Name: theg spermatid protein like
Synonyms: 1700023E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71868
Homologene: 128474
Ric8a
Name: RIC8 guanine nucleotide exchange factor A
Synonyms: synembryn, RIC-8, Ric8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101489
Homologene: 23331
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: 4930564O18Rik, nmf192
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 260305
Homologene: 9024
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Ano3
Name: anoctamin 3
Synonyms: Tmem16c, B230324K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228432
Homologene: 57147
Olfr1392
Name: olfactory receptor 1392
Synonyms: GA_x6K02T2QP88-6141322-6140387, MOR256-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258462
Homologene: 81347
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74682
Homologene: 10814
Gabrg2
Name: gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
Synonyms: Gabrg-2, GABAA-R, gamma2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14406
HGNC: HGNC:4087
Homologene: 22443
Cma2
Name: chymase 2, mast cell
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 545055
VEGA: 14
Homologene: 115745
Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Synonyms: 1alpha(OH)ase, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25(OH)D 1alpha-hydroxylase, VddrI, P450c1, Cyp27b, Vddr, Vdd1, Pddr, Cyp1, Cp2b, Cyp40, P450VD1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13115
HGNC: HGNC:2606
Homologene: 37139
Dlg2
Name: discs large MAGUK scaffold protein 2
Synonyms: LOC382816, A330103J02Rik, B230218P12Rik, Gm21505, Dlgh2, B330007M19Rik, PSD93, Chapsyn-110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 23859
HGNC: HGNC:2901
Homologene: 1046
Methig1
Name: methyltransferase hypoxia inducible domain containing 1
Synonyms: Mettl7a2-Higd1c, UbiE-YGHL1, UbiE2-Hig1-4, AB099516, Mettl7a2Higd1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 554292
Homologene: 128515
Ajuba
Name: ajuba LIM protein
Synonyms: Jub
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16475
VEGA: 14
Homologene: 7789
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: 1110006M24Rik, 0610012C17Rik, PML, PLM, phospholemman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Crtac1
Name: cartilage acidic protein 1
Synonyms: Lotus, Crtac1B, 2810454P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72832
VEGA: 19
Homologene: 23070
Mlf1
Name: myeloid leukemia factor 1
Synonyms: HLS7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17349
HGNC: HGNC:7125
Homologene: 7839
Fam43b
Name: family with sequence similarity 43, member B
Synonyms: OTTMUSG00000009974
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 625638
Homologene: 45810
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 8,595,402 bp
  • T to A, chromosome 1 at 44,056,460 bp
  • A to T, chromosome 1 at 72,192,064 bp
  • A to G, chromosome 1 at 164,195,720 bp
  • A to T, chromosome 1 at 171,256,229 bp
  • A to G, chromosome 1 at 171,389,328 bp
  • T to A, chromosome 2 at 35,283,918 bp
  • T to A, chromosome 2 at 57,112,199 bp
  • G to A, chromosome 2 at 88,987,470 bp
  • T to A, chromosome 2 at 90,471,341 bp
  • T to C, chromosome 2 at 91,679,425 bp
  • T to A, chromosome 2 at 110,682,759 bp
  • A to G, chromosome 2 at 119,903,723 bp
  • G to A, chromosome 3 at 67,399,751 bp
  • A to G, chromosome 3 at 86,776,103 bp
  • C to G, chromosome 3 at 96,559,447 bp
  • T to C, chromosome 3 at 135,601,521 bp
  • A to G, chromosome 3 at 146,646,424 bp
  • A to G, chromosome 3 at 153,933,043 bp
  • G to T, chromosome 4 at 58,082,677 bp
  • A to G, chromosome 4 at 130,166,993 bp
  • C to A, chromosome 4 at 131,808,499 bp
  • C to T, chromosome 4 at 137,946,362 bp
  • G to C, chromosome 4 at 138,395,098 bp
  • A to G, chromosome 4 at 148,489,555 bp
  • A to G, chromosome 4 at 149,344,572 bp
  • T to C, chromosome 4 at 152,135,545 bp
  • A to G, chromosome 4 at 152,557,043 bp
  • A to T, chromosome 4 at 154,984,309 bp
  • A to G, chromosome 5 at 14,540,332 bp
  • A to G, chromosome 5 at 21,831,510 bp
  • C to T, chromosome 5 at 43,737,481 bp
  • C to T, chromosome 5 at 50,001,880 bp
  • T to C, chromosome 5 at 73,041,364 bp
  • T to C, chromosome 5 at 75,637,283 bp
  • T to C, chromosome 5 at 77,059,367 bp
  • T to C, chromosome 5 at 138,298,284 bp
  • G to A, chromosome 6 at 29,438,666 bp
  • T to C, chromosome 6 at 48,458,096 bp
  • C to T, chromosome 6 at 49,417,250 bp
  • A to T, chromosome 6 at 61,570,815 bp
  • T to C, chromosome 6 at 71,238,676 bp
  • A to T, chromosome 6 at 119,963,640 bp
  • C to T, chromosome 7 at 30,958,345 bp
  • G to A, chromosome 7 at 31,053,878 bp
  • T to A, chromosome 7 at 92,438,041 bp
  • G to A, chromosome 7 at 92,625,773 bp
  • A to G, chromosome 7 at 140,861,938 bp
  • T to A, chromosome 8 at 34,115,223 bp
  • C to A, chromosome 8 at 76,909,907 bp
  • A to G, chromosome 8 at 104,125,733 bp
  • T to C, chromosome 8 at 105,387,266 bp
  • T to C, chromosome 8 at 111,918,931 bp
  • T to C, chromosome 8 at 124,948,414 bp
  • C to T, chromosome 9 at 22,076,540 bp
  • T to C, chromosome 10 at 80,713,998 bp
  • T to A, chromosome 10 at 100,603,338 bp
  • T to G, chromosome 10 at 127,048,294 bp
  • A to T, chromosome 11 at 9,328,136 bp
  • T to C, chromosome 11 at 41,976,636 bp
  • A to C, chromosome 11 at 49,293,632 bp
  • T to C, chromosome 11 at 59,549,136 bp
  • A to T, chromosome 11 at 76,237,809 bp
  • T to C, chromosome 11 at 76,797,801 bp
  • A to G, chromosome 11 at 100,698,154 bp
  • G to T, chromosome 11 at 115,802,989 bp
  • A to G, chromosome 12 at 8,978,628 bp
  • A to G, chromosome 13 at 23,738,924 bp
  • G to T, chromosome 14 at 44,989,650 bp
  • C to A, chromosome 14 at 54,577,188 bp
  • G to T, chromosome 14 at 55,569,371 bp
  • T to A, chromosome 14 at 55,971,528 bp
  • T to A, chromosome 14 at 79,064,996 bp
  • A to T, chromosome 15 at 100,353,360 bp
  • T to C, chromosome 16 at 11,158,594 bp
  • C to T, chromosome 16 at 22,961,309 bp
  • T to A, chromosome 17 at 24,376,726 bp
  • A to G, chromosome 18 at 34,808,419 bp
  • T to C, chromosome 18 at 61,262,434 bp
  • T to C, chromosome 18 at 65,624,712 bp
  • T to C, chromosome 19 at 8,909,468 bp
  • T to A, chromosome 19 at 10,551,873 bp
  • A to G, chromosome 19 at 20,620,091 bp
  • T to A, chromosome 19 at 24,378,947 bp
  • G to A, chromosome 19 at 42,283,567 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2281 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040280-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.