Strain Name:
C57BL/6J-MtgxR2336Btlr/Mmmh
Stock Number:
040323-MU
Citation ID:
RRID:MMRRC_040323-MU
Other Names:
R2336 (G1), C57BL/6J-MtgxR2336Btlr
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 9330107J05Rik, 4930431J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73884
Homologene: 52868
Lrrfip2
Name: leucine rich repeat (in FLII) interacting protein 2
Synonyms: 5133400F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71268
HGNC: HGNC:6703
Homologene: 22476
Arhgap21
Name: Rho GTPase activating protein 21
Synonyms: 5530401C11Rik, ARHGAP10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71435
Homologene: 10822
Eprs
Name: glutamyl-prolyl-tRNA synthetase
Synonyms: 2410081F06Rik, 3010002K18Rik, Qprs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107508
HGNC: HGNC:3418
Homologene: 5870
Rbm25
Name: RNA binding motif protein 25
Synonyms: 2610015J01Rik, A130095G20Rik, 2600011C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 67039
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Tent3b, Zcchc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Ddx42
Name: DEAD box helicase 42
Synonyms: B430002H05Rik, 1810047H21Rik, SF3b125, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72047
Homologene: 49137
Arid2
Name: AT rich interactive domain 2 (ARID, RFX-like)
Synonyms: 4432409D24Rik, zipzap/p200, 1700124K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 77044
Homologene: 14601
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, Cd, ska26, skax26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: TFIIIB150, TFIIIB90, TAF3B1, TFC5, Tfnr, G630013P12Rik, B130055N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544971
Homologene: 34582
Gabrr3
Name: gamma-aminobutyric acid (GABA) receptor, rho 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 328699
VEGA: 16
Homologene: 26716
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234362
Homologene: 74376
Gcat
Name: glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
Synonyms: Kbl, aminoacetone synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 26912
VEGA: 15
HGNC: HGNC:4188
Homologene: 8475
Prokr2
Name: prokineticin receptor 2
Synonyms: PKR2, B830005M06Rik, EG-VEGRF2, Gpr73l1, Gpcr73l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 246313
Homologene: 16368
Grik4
Name: glutamate receptor, ionotropic, kainate 4
Synonyms: KA1, 6330551K01Rik, GluRgamma1, KA-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110637
HGNC: HGNC:4582
Homologene: 81829
Fut8
Name: fucosyltransferase 8
Synonyms: alpha (1,6) fucosyltransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 53618
VEGA: 12
HGNC: HGNC:4019
Homologene: 9650
Obi1
Name: ORC ubiquitin ligase 1
Synonyms: 2810449K13Rik, 2610206B13Rik, Rnf219
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72486
VEGA: 14
Homologene: 11578
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Rdh9
Name: retinol dehydrogenase 9
Synonyms: Crad3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103142
Homologene: 129514
Mttp
Name: microsomal triglyceride transfer protein
Synonyms: MTP, 1810043K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17777
HGNC: HGNC:7467
Homologene: 212
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Chrnd
Name: cholinergic receptor, nicotinic, delta polypeptide
Synonyms: Achr-4, Acrd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11447
HGNC: HGNC:1965
Homologene: 37340
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Ppfia3
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
Synonyms: 2410127E16Rik, Liprin-alpha3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76787
HGNC: HGNC:9247
Homologene: 37833
Usp43
Name: ubiquitin specific peptidase 43
Synonyms: C630032K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216835
Homologene: 129879
St3gal6
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Synonyms: ST3Gal VI, 1700023B24Rik, Siat10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 54613
Homologene: 4448
A430110L20Rik
Name: RIKEN cDNA A430110L20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329307
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224576
Homologene: 135824
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: 1600029H12Rik, Psg30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73250
Homologene: 115938
Dtwd2
Name: DTW domain containing 2
Synonyms: 8030470C17Rik, 1190002H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68857
Homologene: 79701
Ero1b
Name: endoplasmic reticulum oxidoreductase 1 beta
Synonyms: 1700065B09Rik, 1300013B24Rik, Ero1lb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67475
VEGA: 13
Homologene: 8740
Gnb2
Name: guanine nucleotide binding protein (G protein), beta 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14693
HGNC: HGNC:4398
Homologene: 68451
Olfr120
Name: olfactory receptor 120
Synonyms: MOR263-3, GA_x6K02T2PSCP-2184981-2185946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258624
Homologene: 110622
Rce1
Name: Ras converting CAAX endopeptidase 1
Synonyms: D19Ertd98e, D19Ertd283e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19671
VEGA: 19
Homologene: 3769
Olfr458
Name: olfactory receptor 458
Synonyms: GA_x6K02T2P3E9-5100053-5100994, MOR257-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258436
Homologene: 133704
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 63,303,464 bp
  • T to C, chromosome 1 at 87,194,893 bp
  • T to A, chromosome 1 at 181,227,641 bp
  • T to A, chromosome 1 at 185,411,374 bp
  • G to A, chromosome 2 at 20,880,051 bp
  • C to T, chromosome 2 at 130,957,954 bp
  • A to T, chromosome 2 at 132,381,439 bp
  • T to C, chromosome 3 at 3,641,224 bp
  • A to T, chromosome 3 at 138,116,095 bp
  • A to T, chromosome 5 at 137,529,198 bp
  • A to G, chromosome 6 at 42,460,729 bp
  • A to G, chromosome 6 at 134,507,583 bp
  • T to C, chromosome 7 at 17,747,375 bp
  • T to C, chromosome 7 at 45,356,697 bp
  • G to T, chromosome 8 at 69,613,907 bp
  • C to T, chromosome 9 at 42,566,355 bp
  • A to G, chromosome 9 at 111,222,215 bp
  • A to G, chromosome 10 at 127,788,755 bp
  • G to A, chromosome 11 at 67,891,432 bp
  • A to G, chromosome 11 at 106,231,150 bp
  • G to A, chromosome 11 at 119,414,604 bp
  • A to G, chromosome 12 at 77,412,956 bp
  • T to A, chromosome 12 at 83,651,418 bp
  • G to A, chromosome 13 at 12,579,161 bp
  • G to T, chromosome 13 at 59,799,054 bp
  • A to T, chromosome 13 at 100,053,002 bp
  • G to A, chromosome 14 at 104,478,882 bp
  • A to G, chromosome 15 at 73,266,116 bp
  • G to A, chromosome 15 at 79,030,980 bp
  • A to G, chromosome 15 at 96,362,549 bp
  • A to T, chromosome 16 at 58,493,704 bp
  • C to T, chromosome 16 at 59,429,950 bp
  • T to C, chromosome 17 at 20,268,208 bp
  • T to C, chromosome 17 at 25,250,404 bp
  • A to T, chromosome 17 at 37,726,798 bp
  • A to T, chromosome 17 at 71,023,194 bp
  • A to G, chromosome 18 at 49,700,253 bp
  • C to G, chromosome 19 at 4,624,004 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2336 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040323-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.