Strain Name:
C57BL/6J-MtgxR2402Btlr/Mmmh
Stock Number:
040368-MU
Citation ID:
RRID:MMRRC_040368-MU
Other Names:
R2402 (G1), C57BL/6J-MtgxR2402Btlr
Major Collection:

Gene Information

Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Synonyms: 5-HT3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 15561
VEGA: 9
HGNC: HGNC:5297
Homologene: 671
Atic
Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: 2610509C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108147
HGNC: HGNC:794
Homologene: 2983
Cr1l
Name: complement component (3b/4b) receptor 1-like
Synonyms: mCRY, Crry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12946
HGNC: HGNC:2335
Homologene: 128275
Akap10
Name: A kinase (PRKA) anchor protein 10
Synonyms: D-AKAP2, 1500031L16Rik, B130049N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56697
HGNC: HGNC:368
Homologene: 32452
Gon4l
Name: gon-4-like (C.elegans)
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76022
Homologene: 13002
Nr4a1
Name: nuclear receptor subfamily 4, group A, member 1
Synonyms: Nur77, TIS1, TR3, N10, NP10, GFRP1, NGFI-B, Hbr-1, Gfrp, Hbr1, Hmr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15370
VEGA: 15
HGNC: HGNC:7980
Homologene: 1612
Nisch
Name: nischarin
Synonyms: 1200007D05Rik, 3202002H23Rik, edsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 64652
Homologene: 136161
Tcf12
Name: transcription factor 12
Synonyms: ME1, ALF1, HEB, HTF4, HTF-4, REB, bHLHb20, HEBAlt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21406
Homologene: 40774
Iars
Name: isoleucine-tRNA synthetase
Synonyms: E430001P04Rik, 2510016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105148
HGNC: HGNC:5330
Homologene: 5325
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: Wdr11, Ndrp, 2810004D21Rik, 4632404O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83946
Homologene: 41209
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 2010005B09Rik, 4432404J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66691
Homologene: 32637
Cep350
Name: centrosomal protein 350
Synonyms: 6430546F08Rik, 4933409L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74081
Homologene: 8879
Dtna
Name: dystrobrevin alpha
Synonyms: alpha-dystrobrevin, A0, 87K protein, Dtn, adbn, a-DB-1, 2210407P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13527
VEGA: 18
HGNC: HGNC:3057
Homologene: 20362
Ift74
Name: intraflagellar transport 74
Synonyms: 1700029H06Rik, Cmg1, Ccdc2, b2b796Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67694
Homologene: 11831
Bbs9
Name: Bardet-Biedl syndrome 9 (human)
Synonyms: EST 3159894, E130103I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319845
Homologene: 44480
Doc2a
Name: double C2, alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13446
HGNC: HGNC:2985
Homologene: 2657
Dpy19l2
Name: dpy-19-like 2 (C. elegans)
Synonyms: 4932443J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320752
VEGA: 9
Homologene: 77569
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: 1200015F23Rik, Fam82a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67809
Homologene: 34926
Angptl8
Name: angiopoietin-like 8
Synonyms: Rifl, Lipasin, Gm6484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 624219
VEGA: 9
Homologene: 83285
Neto2
Name: neuropilin (NRP) and tolloid (TLL)-like 2
Synonyms: 5530601C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74513
Homologene: 32387
Ctsa
Name: cathepsin A
Synonyms: PPCA, Ppgb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19025
HGNC: HGNC:9251
Homologene: 80163
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59035
Homologene: 10990
Tstd2
Name: thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 272027
Homologene: 16403
Reg3g
Name: regenerating islet-derived 3 gamma
Synonyms: RegIII (gamma)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19695
Homologene: 128216
Chp2
Name: calcineurin-like EF hand protein 2
Synonyms: Cbhp2, 2010110P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 70261
Homologene: 11131
Olfr914
Name: olfactory receptor 914
Synonyms: GA_x6K02T2PVTD-32308823-32309773, MOR165-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258782
VEGA: 9
Homologene: 115511
Unc13b
Name: unc-13 homolog B
Synonyms: Unc13h2, Munc13-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22249
Homologene: 31376
Exph5
Name: exophilin 5
Synonyms: slac2-b, B130009M24Rik, AC079869.22gm5, Slac2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320051
Homologene: 9007
Il12rb2
Name: interleukin 12 receptor, beta 2
Synonyms: IL-12RB2, Ifnm, A930027I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16162
HGNC: HGNC:5972
Homologene: 1197
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 545260
Homologene: 44428
Zbtb41
Name: zinc finger and BTB domain containing 41
Synonyms: 8430415N23Rik, 9830132G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226470
Homologene: 27795
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: A230067G21Rik, RGC2, AS250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241694
Homologene: 28131
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Abcc12
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Synonyms: MRP9, 4930467B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244562
Homologene: 57211
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: Casr-rs2, EG637873, Gprc2a-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637873
Homologene: 129683
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Sos2
Name: SOS Ras/Rho guanine nucleotide exchange factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20663
Homologene: 38253
Nxpe5
Name: neurexophilin and PC-esterase domain family, member 5
Synonyms: Fam55 related, BC055004
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381680
Homologene: 134143
Abcc6
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Synonyms: DCC, Mrp6, Dyscalc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27421
HGNC: HGNC:57
Homologene: 55559
Caskin1
Name: CASK interacting protein 1
Synonyms: C630036E02Rik, 3300002N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268932
VEGA: 17
Homologene: 25873
Cgnl1
Name: cingulin-like 1
Synonyms: 4933421H10Rik, Jacop, 9930020M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68178
Homologene: 41901
Klra2
Name: killer cell lectin-like receptor, subfamily A, member 2
Synonyms: Ly49b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16633
Homologene: 133782
Qprt
Name: quinolinate phosphoribosyltransferase
Synonyms: QPRTase, nicotinate-nucleotide pyrophosphorylase, 2410027J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67375
HGNC: HGNC:9755
Homologene: 8623
Tle5
Name: TLE family member 5, transcriptional modulator
Synonyms: Grg5, Grg, AES, Aes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14797
VEGA: 10
HGNC: HGNC:307
Homologene: 879
Ctsj
Name: cathepsin J
Synonyms: rat gene/Cathepsin L-related protein, CatRLP, CATP, Cat P, Ctsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 26898
VEGA: 13
Homologene: 137246
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71872
Homologene: 70273
Rimbp2
Name: RIMS binding protein 2
Synonyms: A930033C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231760
Homologene: 14672
Niban1
Name: niban apoptosis regulator 1
Synonyms: Niban, Fam129a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 63913
Homologene: 62170
Acvrl1
Name: activin A receptor, type II-like 1
Synonyms: Alk1, activin receptor-like kinase-1, Acvrlk1, Alk-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11482
HGNC: HGNC:175
Homologene: 20058
Usb1
Name: U6 snRNA biogenesis 1
Synonyms: AA960436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 101985
Homologene: 11611
Ica1l
Name: islet cell autoantigen 1-like
Synonyms: 1700030B17Rik, Als2cr15, b2b3465Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70375
Homologene: 16323
Zfp821
Name: zinc finger protein 821
Synonyms: 4930566A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75871
Homologene: 32345
H2-T10
Name: histocompatibility 2, T region locus 10
Synonyms: H-2T10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15024
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR3, VEGFR-3, Flt-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Bcl2a1b
Name: B cell leukemia/lymphoma 2 related protein A1b
Synonyms: A1-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12045
HGNC: HGNC:991
Homologene: 2988
Exoc3l4
Name: exocyst complex component 3-like 4
Synonyms: 1600013K19Rik, 1200009I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74190
VEGA: 12
Homologene: 41760
Zfp773
Name: zinc finger protein 773
Synonyms: 2810409K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76373
Homologene: 137393
Olfr832
Name: olfactory receptor 832
Synonyms: GA_x6K02T2PVTD-12687800-12688738, MOR153-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258075
HGNC: HGNC:8467
Homologene: 128143
Fhl3
Name: four and a half LIM domains 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14201
HGNC: HGNC:3704
Homologene: 37928
Tspan32
Name: tetraspanin 32
Synonyms: D7Wsu37e, Tssc6, Art-1, Tspan32, Phemx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27027
Homologene: 10650
Gm7337
Name: predicted gene 7337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 654494
Heatr3
Name: HEAT repeat containing 3
Synonyms: C030036P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234549
Homologene: 45429
Bcl2a1d
Name: B cell leukemia/lymphoma 2 related protein A1d
Synonyms: A1-d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12047
HGNC: HGNC:991
Homologene: 2988
Tubb2b
Name: tubulin, beta 2B class IIB
Synonyms: 2410129E14Rik, brdp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 73710
VEGA: 13
Homologene: 49734
Tgtp2
Name: T cell specific GTPase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100039796
Homologene: 129991
Rhobtb1
Name: Rho-related BTB domain containing 1
Synonyms: 1700008H16Rik, 3110048G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69288
Homologene: 8892
Flvcr2
Name: feline leukemia virus subgroup C cellular receptor 2
Synonyms: CCT, Mfsd7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217721
VEGA: 12
Homologene: 9840
Pstpip2
Name: proline-serine-threonine phosphatase-interacting protein 2
Synonyms: cmo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19201
VEGA: 18
HGNC: HGNC:9581
Homologene: 69150
Cd302
Name: CD302 antigen
Synonyms: 1110055L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66205
Homologene: 8919
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,213,017 bp
  • T to C, chromosome 1 at 60,006,292 bp
  • T to A, chromosome 1 at 71,569,057 bp
  • A to C, chromosome 1 at 139,423,185 bp
  • G to T, chromosome 1 at 139,423,187 bp
  • A to G, chromosome 1 at 151,689,614 bp
  • A to T, chromosome 1 at 155,863,136 bp
  • T to A, chromosome 1 at 195,106,902 bp
  • G to A, chromosome 2 at 34,678,643 bp
  • T to C, chromosome 2 at 42,323,730 bp
  • A to G, chromosome 2 at 60,257,068 bp
  • A to G, chromosome 2 at 119,153,370 bp
  • A to T, chromosome 2 at 146,353,192 bp
  • A to T, chromosome 2 at 164,834,893 bp
  • G to T, chromosome 3 at 88,859,043 bp
  • A to G, chromosome 4 at 43,095,843 bp
  • A to T, chromosome 4 at 46,117,093 bp
  • A to G, chromosome 4 at 94,627,082 bp
  • T to C, chromosome 4 at 124,705,688 bp
  • C to T, chromosome 5 at 87,851,029 bp
  • T to C, chromosome 5 at 128,784,888 bp
  • T to A, chromosome 5 at 138,230,520 bp
  • T to A, chromosome 6 at 67,316,180 bp
  • A to T, chromosome 6 at 78,467,492 bp
  • A to G, chromosome 6 at 131,243,901 bp
  • A to G, chromosome 7 at 7,133,185 bp
  • A to G, chromosome 7 at 42,300,105 bp
  • A to T, chromosome 7 at 46,015,575 bp
  • A to G, chromosome 7 at 122,221,172 bp
  • C to A, chromosome 7 at 126,848,747 bp
  • C to T, chromosome 7 at 127,108,360 bp
  • T to C, chromosome 7 at 143,017,296 bp
  • T to C, chromosome 8 at 85,690,912 bp
  • T to A, chromosome 8 at 86,509,141 bp
  • T to C, chromosome 8 at 88,144,572 bp
  • T to A, chromosome 8 at 95,343,131 bp
  • C to T, chromosome 8 at 109,721,240 bp
  • T to A, chromosome 9 at 18,945,200 bp
  • T to A, chromosome 9 at 21,583,540 bp
  • T to C, chromosome 9 at 21,835,816 bp
  • C to T, chromosome 9 at 22,646,063 bp
  • T to C, chromosome 9 at 24,581,248 bp
  • T to C, chromosome 9 at 38,607,101 bp
  • C to T, chromosome 9 at 48,901,495 bp
  • C to A, chromosome 9 at 53,374,925 bp
  • A to G, chromosome 9 at 71,725,179 bp
  • A to T, chromosome 9 at 71,856,510 bp
  • C to T, chromosome 9 at 82,875,305 bp
  • A to T, chromosome 9 at 88,731,496 bp
  • A to G, chromosome 9 at 89,199,742 bp
  • G to A, chromosome 10 at 69,270,424 bp
  • T to A, chromosome 10 at 81,564,878 bp
  • T to C, chromosome 11 at 49,059,130 bp
  • A to G, chromosome 11 at 49,637,819 bp
  • T to C, chromosome 11 at 59,131,646 bp
  • T to C, chromosome 11 at 61,915,222 bp
  • T to C, chromosome 11 at 118,125,974 bp
  • A to G, chromosome 12 at 51,745,534 bp
  • T to C, chromosome 12 at 69,596,799 bp
  • A to G, chromosome 12 at 85,783,003 bp
  • A to G, chromosome 12 at 111,422,256 bp
  • T to C, chromosome 13 at 34,128,226 bp
  • T to C, chromosome 13 at 49,724,800 bp
  • C to T, chromosome 13 at 61,000,574 bp
  • T to A, chromosome 14 at 31,185,014 bp
  • A to G, chromosome 15 at 101,137,399 bp
  • G to T, chromosome 15 at 101,271,737 bp
  • T to A, chromosome 17 at 24,503,808 bp
  • A to T, chromosome 17 at 36,117,739 bp
  • T to A, chromosome 18 at 23,595,478 bp
  • T to C, chromosome 18 at 60,916,467 bp
  • T to A, chromosome 18 at 77,854,864 bp
  • A to T, chromosome 19 at 17,474,834 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2402 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040368-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.