Strain Name:
C57BL/6J-MtgxR2420Btlr/Mmmh
Stock Number:
040382-MU
Citation ID:
RRID:MMRRC_040382-MU
Other Names:
R2420 (G1), C57BL/6J-MtgxR2420Btlr
Major Collection:

Gene Information

Fga
Name: fibrinogen alpha chain
Synonyms: Fib, ENSMUSG00000059807
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14161
HGNC: HGNC:3661
Homologene: 428
Pax3
Name: paired box 3
Synonyms: Pax-3, Splchl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18505
HGNC: HGNC:8617
Homologene: 22494
Tyr
Name: tyrosinase
Synonyms: skc35, Oca1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22173
Homologene: 30969
Pak1
Name: p21 (RAC1) activated kinase 1
Synonyms: PAK-1, Paka
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18479
HGNC: HGNC:8590
Homologene: 1936
Glrb
Name: glycine receptor, beta subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14658
HGNC: HGNC:4329
Homologene: 20224
Mfn1
Name: mitofusin 1
Synonyms: 6330416C07Rik, 2310002F04Rik, D3Ertd265e, HR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67414
Homologene: 11481
Cwf19l2
Name: CWF19-like 2, cell cycle control (S. pombe)
Synonyms: 3230401L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244672
Homologene: 12366
Dnajc21
Name: DnaJ heat shock protein family (Hsp40) member C21
Synonyms: 9930116P15Rik, 4930461P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78244
Homologene: 6752
Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, 5730461F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 114715
Homologene: 24919
Zfp13
Name: zinc finger protein 13
Synonyms: Krox-8, Zfp-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22654
VEGA: 17
Homologene: 2580
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: 6430573H23Rik, Prkwnk1, EG406236, Hsn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232341
Homologene: 14253
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81702
Homologene: 82403
Dhcr24
Name: 24-dehydrocholesterol reductase
Synonyms: 5830417J06Rik, seladin-1, 3-beta-hydroxysterol delta-24 reductase, 2310076D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74754
HGNC: HGNC:2859
Homologene: 8850
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Atxn2
Name: ataxin 2
Synonyms: ATX2, 9630045M23Rik, Sca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20239
Homologene: 2234
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 1700021E15Rik, 4932411G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73254
Homologene: 35455
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Wdr45b
Name: WD repeat domain 45B
Synonyms: D16Bwg0193e, 0610008N23Rik, Wdr45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66840
Homologene: 6028
Jcad
Name: junctional cadherin 5 associated
Synonyms: 9430020K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240185
VEGA: 18
Homologene: 19370
Uba6
Name: ubiquitin-like modifier activating enzyme 6
Synonyms: 5730469D23Rik, Ube1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231380
Homologene: 10080
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: 1110034C04Rik, Smek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68734
VEGA: 12
Homologene: 69510
Gas1
Name: growth arrest specific 1
Synonyms: Gas-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14451
HGNC: HGNC:4165
Homologene: 1548
Krt10
Name: keratin 10
Synonyms: K10, K1C1, suprabasal cytokeratin 10, Krt-1.10, cytokeratin 10, keratin 10, D130054E02Rik, Krt1-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16661
HGNC: HGNC:6413
Homologene: 137236
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: D330024H06Rik, A930031B09Rik, Ankrd15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107351
Homologene: 17706
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213783
Homologene: 18897
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52397
Homologene: 12971
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Egln1
Name: egl-9 family hypoxia-inducible factor 1
Synonyms: SM-20, ORF13, Phd2, Hif-p4h-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 112405
HGNC: HGNC:1232
Homologene: 56936
Katnip
Name: katanin interacting protein
Synonyms: D430042O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233865
Homologene: 45841
Tmub2
Name: transmembrane and ubiquitin-like domain containing 2
Synonyms: 2010008E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72053
Homologene: 18581
Chst9
Name: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
Synonyms: GalNAc4ST-2, 5430438D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 71367
Homologene: 12861
Prickle1
Name: prickle planar cell polarity protein 1
Synonyms: 1110058P22Rik, mpk1, b2b019Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 106042
Homologene: 17686
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh-4, C130041O22Rik, Zfh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, POMFIL1, 4732483H20Rik, unc53H3, steerin 3, 9630020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 260315
Homologene: 56688
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: basilin, FOAP-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, Unc13h3, D9Ertd414e, 1500037O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208898
Homologene: 45443
Arhgap29
Name: Rho GTPase activating protein 29
Synonyms: 6720461J18Rik, Parg1, C76601, B130017I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214137
Homologene: 3539
Prss45
Name: protease, serine 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 260408
Homologene: 51905
Adamts3
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Olfr470
Name: olfactory receptor 470
Synonyms: GA_x6K02T2PBJ9-10175273-10174329, MOR204-22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258417
Olfr975
Name: olfactory receptor 975
Synonyms: GA_x6K02T2PVTD-33651220-33650288, MOR224-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258825
VEGA: 9
Homologene: 27275
Krt13
Name: keratin 13
Synonyms: Krt-1.13, K13, Krt1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16663
HGNC: HGNC:6415
Homologene: 40740
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Spag17
Name: sperm associated antigen 17
Synonyms: 4931427F14Rik, PF6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74362
Homologene: 52601
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17837
Homologene: 136663
Mypn
Name: myopalladin
Synonyms: 1110056A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 68802
VEGA: 10
Homologene: 23778
Psd4
Name: pleckstrin and Sec7 domain containing 4
Synonyms: SEC7 homolog, EFA6B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215632
Homologene: 8261
Esp6
Name: exocrine gland secreted peptide 6
Synonyms: Esp5, Gm5494
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433107
VEGA: 17
Eme1
Name: essential meiotic structure-specific endonuclease 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268465
Homologene: 16123
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: 7M1, Pira3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18726
HGNC: HGNC:6607
Homologene: 134028
Serpinb8
Name: serine (or cysteine) peptidase inhibitor, clade B, member 8
Synonyms: ovalbumin, CAP-2, CAP2, Spi8, NK10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20725
HGNC: HGNC:8952
Homologene: 74445
Shank3
Name: SH3 and multiple ankyrin repeat domains 3
Synonyms: ProSAP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 58234
Homologene: 75163
Acsm2
Name: acyl-CoA synthetase medium-chain family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233799
Homologene: 70404
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627569
Homologene: 129606
Fbp1
Name: fructose bisphosphatase 1
Synonyms: FBPase brain isoform, FBPase liver, Fbp-2, Fbp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14121
HGNC: HGNC:3606
Homologene: 55467
Olfr1219
Name: olfactory receptor 1219
Synonyms: GA_x6K02T2Q125-50555603-50554668, MOR233-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258901
Homologene: 27292
6820408C15Rik
Name: RIKEN cDNA 6820408C15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228778
Homologene: 51916
Psmb10
Name: proteasome (prosome, macropain) subunit, beta type 10
Synonyms: Mecl1, Mecl-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19171
HGNC: HGNC:9538
Homologene: 20616
H2-M10.5
Name: histocompatibility 2, M region locus 10.5
Synonyms: 6.9H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224761
Homologene: 117973
Prl8a2
Name: prolactin family 8, subfamily a, member 2
Synonyms: D/tPRP, DPRP, mdPRP, Dtprp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13529
Homologene: 49230
Actr5
Name: ARP5 actin-related protein 5
Synonyms: B430109J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109275
Homologene: 6818
Ly6g6e
Name: lymphocyte antigen 6 complex, locus G6E
Synonyms: 2310011I02Rik, G6e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70274
Homologene: 41553
Terb1
Name: telomere repeat binding bouquet formation protein 1
Synonyms: 4930532D21Rik, Ccdc79
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320022
Homologene: 18330
Ltc4s
Name: leukotriene C4 synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17001
HGNC: HGNC:6719
Homologene: 7406
Prxl2c
Name: peroxiredoxin like 2C
Synonyms: 1110018J18Rik, Aaed1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66129
VEGA: 13
Homologene: 7192
Pttg1ip2
Name: PTTG1IP family member 2
Synonyms: LOC381716, 1700015F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381716
Homologene: 136447
Olfr1290
Name: olfactory receptor 1290
Synonyms: GA_x6K02T2Q125-72541649-72540711, MOR248-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257662
Homologene: 74248
Ndufaf1
Name: NADH:ubiquinone oxidoreductase complex assembly factor 1
Synonyms: CGI-65, CIA30, 2410001M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69702
Homologene: 32289
Ccdc137
Name: coiled-coil domain containing 137
Synonyms: 3110023B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67291
Homologene: 34992
Entpd2
Name: ectonucleoside triphosphate diphosphohydrolase 2
Synonyms: NTPDase2, Cd39l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12496
HGNC: HGNC:3364
Homologene: 20333
Gm17421
Name: predicted gene, 17421
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Olfr178
Name: olfactory receptor 178
Synonyms: GA_x54KRFPKG5P-55108059-55107100, MOR184-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258999
Homologene: 79412
Mmaa
Name: methylmalonic aciduria (cobalamin deficiency) type A
Synonyms: 2810018E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109136
Homologene: 14586
Smc1a
Name: structural maintenance of chromosomes 1A
Synonyms: Smc1, SB1.8, SMCB, 5830426I24Rik, Smc1alpha, Smc1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 24061
Homologene: 4597
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 78,196,864 bp
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • G to A, chromosome 1 at 107,602,925 bp
  • T to G, chromosome 2 at 24,401,241 bp
  • T to C, chromosome 2 at 25,399,283 bp
  • T to C, chromosome 2 at 89,074,992 bp
  • T to C, chromosome 2 at 111,489,257 bp
  • T to C, chromosome 2 at 117,165,010 bp
  • T to C, chromosome 2 at 119,655,737 bp
  • A to G, chromosome 2 at 152,429,001 bp
  • T to C, chromosome 2 at 158,636,081 bp
  • A to G, chromosome 2 at 180,182,956 bp
  • C to A, chromosome 3 at 5,390,405 bp
  • A to G, chromosome 3 at 32,569,515 bp
  • A to G, chromosome 3 at 80,860,235 bp
  • A to T, chromosome 3 at 83,033,154 bp
  • T to A, chromosome 3 at 100,027,619 bp
  • A to G, chromosome 3 at 121,973,980 bp
  • G to T, chromosome 4 at 106,561,094 bp
  • T to C, chromosome 5 at 5,455,912 bp
  • A to G, chromosome 5 at 86,132,616 bp
  • A to G, chromosome 5 at 89,683,175 bp
  • A to T, chromosome 5 at 90,289,320 bp
  • A to G, chromosome 5 at 106,637,244 bp
  • A to C, chromosome 5 at 108,228,588 bp
  • A to G, chromosome 5 at 109,086,532 bp
  • A to T, chromosome 5 at 121,802,079 bp
  • A to G, chromosome 6 at 119,936,367 bp
  • C to A, chromosome 6 at 122,083,460 bp
  • A to G, chromosome 7 at 3,914,858 bp
  • T to A, chromosome 7 at 87,429,189 bp
  • A to T, chromosome 7 at 97,854,479 bp
  • T to C, chromosome 7 at 107,844,818 bp
  • T to C, chromosome 7 at 119,563,634 bp
  • C to T, chromosome 7 at 125,728,306 bp
  • T to A, chromosome 8 at 79,281,432 bp
  • T to C, chromosome 8 at 104,498,595 bp
  • A to G, chromosome 8 at 105,937,302 bp
  • T to C, chromosome 8 at 124,948,246 bp
  • A to G, chromosome 9 at 3,411,341 bp
  • A to G, chromosome 9 at 39,950,528 bp
  • T to C, chromosome 9 at 73,931,547 bp
  • A to G, chromosome 9 at 110,839,092 bp
  • G to A, chromosome 10 at 3,958,048 bp
  • G to T, chromosome 10 at 63,192,869 bp
  • A to C, chromosome 10 at 109,863,813 bp
  • A to G, chromosome 11 at 50,237,339 bp
  • T to A, chromosome 11 at 72,755,896 bp
  • A to G, chromosome 11 at 84,009,224 bp
  • A to G, chromosome 11 at 94,645,814 bp
  • G to A, chromosome 11 at 99,387,107 bp
  • A to T, chromosome 11 at 100,120,051 bp
  • T to A, chromosome 11 at 102,287,755 bp
  • G to A, chromosome 11 at 120,462,264 bp
  • T to C, chromosome 11 at 121,330,246 bp
  • A to G, chromosome 12 at 101,042,653 bp
  • T to A, chromosome 12 at 113,369,487 bp
  • A to G, chromosome 13 at 27,348,913 bp
  • G to T, chromosome 13 at 60,176,930 bp
  • T to C, chromosome 13 at 62,871,306 bp
  • A to G, chromosome 13 at 64,292,239 bp
  • T to A, chromosome 14 at 50,834,023 bp
  • A to G, chromosome 15 at 10,461,935 bp
  • CT to CTTGGATT, chromosome 15 at 10,537,562 bp
  • G to A, chromosome 15 at 10,537,566 bp
  • A to T, chromosome 15 at 89,521,210 bp
  • A to G, chromosome 15 at 93,503,637 bp
  • T to C, chromosome 16 at 58,889,965 bp
  • T to A, chromosome 17 at 20,227,835 bp
  • A to C, chromosome 17 at 23,576,212 bp
  • G to A, chromosome 17 at 35,078,146 bp
  • A to G, chromosome 17 at 36,774,999 bp
  • A to T, chromosome 17 at 40,578,709 bp
  • A to T, chromosome 17 at 67,750,553 bp
  • A to G, chromosome 17 at 71,274,279 bp
  • T to A, chromosome 17 at 74,660,614 bp
  • T to C, chromosome 18 at 4,675,952 bp
  • A to T, chromosome 18 at 15,452,284 bp
  • C to T, chromosome 19 at 9,009,256 bp
  • T to C, chromosome 19 at 25,410,457 bp
  • A to G, chromosome X at 152,047,975 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2420 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040382-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.