Strain Name:
C57BL/6J-MtgxR2919Btlr/Mmmh
Stock Number:
040504-MU
Citation ID:
RRID:MMRRC_040504-MU
Other Names:
R2919 (G1), C57BL/6J-MtgxR2919Btlr
Major Collection:

Gene Information

Sim1
Name: single-minded family bHLH transcription factor 1
Synonyms: bHLHe14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20464
VEGA: 10
Homologene: 3715
Sdf2
Name: stromal cell derived factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20316
Homologene: 5045
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC386488, B3bp, LOC333789
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Commd9
Name: COMM domain containing 9
Synonyms: 1810029F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76501
Homologene: 8584
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Slc39a4
Name: solute carrier family 39 (zinc transporter), member 4
Synonyms: 1600025H15Rik, zip4, AWMS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72027
VEGA: 15
Homologene: 15638
Fgfr3
Name: fibroblast growth factor receptor 3
Synonyms: HBGFR, Fgfr-3, sam3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14184
HGNC: HGNC:3690
Homologene: 55437
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: FLASH, D4Ertd659e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26885
HGNC: HGNC:1510
Homologene: 8066
Pfkp
Name: phosphofructokinase, platelet
Synonyms: PFK-C, 9330125N24Rik, 1200015H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56421
HGNC: HGNC:8878
Homologene: 20579
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 5430439G14Rik, 6330406J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71389
Homologene: 32772
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: 9630025B04Rik, MPP9, B930097C17Rik, 4930548D04Rik, MPP-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Tmem107
Name: transmembrane protein 107
Synonyms: 1110004B13Rik, 2810049P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66910
Homologene: 12052
Syk
Name: spleen tyrosine kinase
Synonyms: Sykb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20963
Homologene: 2390
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Zbtb5
Name: zinc finger and BTB domain containing 5
Synonyms: 9430083K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230119
Homologene: 8913
Mmrn2
Name: multimerin 2
Synonyms: Emilin3, EndoGlyx-1, ENDOGLYX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105450
VEGA: 14
Homologene: 11697
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: PRO1038, D1Ucla2, Als2cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
Agbl1
Name: ATP/GTP binding protein-like 1
Synonyms: EG244071, Nna1-l1, Ccp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244071
Homologene: 17552
Slc13a5
Name: solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms: mINDY, Nact, NaC2/NaCT, Indy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237831
Homologene: 21941
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Kif1a
Name: kinesin family member 1A
Synonyms: C630002N23Rik, Kns1, N-3 kinesin, LOC381283, ATSV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241514
Homologene: 18461
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: mdig, Megf7, 6430526J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Atg9b
Name: autophagy related 9B
Synonyms: eONE, Nos3as, LOC213948, Apg9l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 213948
Homologene: 72638
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
4921528O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Parp3
Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: PARP-3, A930002C11Rik, Adprt3, Adprtl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235587
HGNC: HGNC:273
Homologene: 4005
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234463
Homologene: 32403
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mar, Mart1, Mor1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 353326
VEGA: 12
Homologene: 120261
Meak7
Name: MTOR associated protein , eak-7 homolog
Synonyms: 4632415K11Rik, Tldc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74347
Homologene: 32494
Als2cl
Name: ALS2 C-terminal like
Synonyms: mRn.49018, D930044G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235633
Homologene: 17152
Thsd7b
Name: thrombospondin, type I, domain containing 7B
Synonyms: 1700074E13Rik, D130067I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210417
Homologene: 18180
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243659
Homologene: 49545
Olfr690
Name: olfactory receptor 690
Synonyms: GA_x6K02T2PBJ9-7959171-7958224, MOR31-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56860
Homologene: 10653
Tmbim7
Name: transmembrane BAX inhibitor motif containing 7
Synonyms: 4930403J02Rik, 4930500J03Rik, Tmbim1b, 4930511M11Rik, Lfg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75010
Homologene: 81927
Sult1d1
Name: sulfotransferase family 1D, member 1
Synonyms: 5033411P13Rik, tyrosine-ester sulfotransferase, Sultn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 53315
Homologene: 124464
Sgk2
Name: serum/glucocorticoid regulated kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27219
Homologene: 8446
Xirp1
Name: xin actin-binding repeat containing 1
Synonyms: Xin, mXin alpha, Cmya1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22437
VEGA: 9
Homologene: 7998
Fbxl12
Name: F-box and leucine-rich repeat protein 12
Synonyms: 3110048D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 30843
Homologene: 32198
Flot2
Name: flotillin 2
Synonyms: reggie-2, Esa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14252
HGNC: HGNC:3758
Homologene: 3293
Ugt2b5
Name: UDP glucuronosyltransferase 2 family, polypeptide B5
Synonyms: m-1, Udpgt-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22238
Homologene: 137225
Slc5a11
Name: solute carrier family 5 (sodium/glucose cotransporter), member 11
Synonyms: 2010013B02Rik, Kst1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233836
Homologene: 14184
Edem2
Name: ER degradation enhancer, mannosidase alpha-like 2
Synonyms: 9530090G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 108687
Homologene: 10075
Gm5884
Name: predicted pseudogene 5884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545878
Slc38a3
Name: solute carrier family 38, member 3
Synonyms: 0610012J02Rik, D9Ucla2, Snat3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76257
Homologene: 4983
Cd1d2
Name: CD1d2 antigen
Synonyms: Cd1b, CD1.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12480
HGNC: HGNC:1637
2310002L09Rik
Name: RIKEN cDNA 2310002L09 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71886
Homologene: 36448
Pfkfb3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Synonyms: E330010H22Rik, uPFK-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 170768
HGNC: HGNC:8874
Homologene: 88708
Pla2g4d
Name: phospholipase A2, group IVD
Synonyms: Pla2delta, 2610311B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78390
Homologene: 52252
Slfnl1
Name: schlafen like 1
Synonyms: 4933406A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 194219
Homologene: 44913
Hdac1-ps
Name: histone deacetylase 1, pseudogene
Synonyms: Gm10093, EG15181
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15181
VEGA: 17
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23801
Homologene: 8013
Oxgr1
Name: oxoglutarate (alpha-ketoglutarate) receptor 1
Synonyms: LOC239283, Gpr99, Gpr80, Cysltr3, P2Y15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239283
VEGA: 14
HGNC: HGNC:4531
Homologene: 25878
Olfr1000
Name: olfactory receptor 1000
Synonyms: GA_x6K02T2Q125-47087719-47086775, MOR175-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257899
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 58,992,669 bp
  • A to G, chromosome 1 at 93,046,742 bp
  • A to G, chromosome 1 at 130,189,850 bp
  • A to C, chromosome 1 at 163,056,772 bp
  • C to T, chromosome 2 at 11,484,327 bp
  • A to C, chromosome 2 at 41,770,899 bp
  • A to G, chromosome 2 at 82,235,816 bp
  • G to A, chromosome 2 at 85,608,410 bp
  • A to G, chromosome 2 at 91,490,730 bp
  • G to A, chromosome 2 at 101,886,331 bp
  • T to C, chromosome 2 at 120,281,627 bp
  • T to C, chromosome 2 at 155,709,027 bp
  • T to G, chromosome 2 at 160,967,880 bp
  • T to G, chromosome 2 at 162,999,195 bp
  • C to A, chromosome 2 at 162,999,205 bp
  • C to G, chromosome 3 at 86,987,680 bp
  • A to G, chromosome 4 at 32,645,343 bp
  • T to C, chromosome 4 at 44,994,790 bp
  • A to T, chromosome 4 at 73,950,608 bp
  • G to T, chromosome 4 at 120,533,078 bp
  • G to A, chromosome 5 at 3,673,188 bp
  • T to A, chromosome 5 at 24,391,544 bp
  • A to G, chromosome 5 at 33,733,940 bp
  • G to A, chromosome 5 at 65,807,098 bp
  • A to G, chromosome 5 at 87,125,407 bp
  • A to G, chromosome 5 at 87,559,755 bp
  • G to A, chromosome 5 at 124,261,006 bp
  • A to G, chromosome 6 at 128,645,058 bp
  • T to A, chromosome 6 at 131,313,004 bp
  • G to A, chromosome 7 at 76,414,658 bp
  • C to T, chromosome 7 at 105,329,860 bp
  • GGTGC to G, chromosome 7 at 123,239,372 bp
  • A to T, chromosome 8 at 77,604,647 bp
  • C to A, chromosome 8 at 81,985,329 bp
  • G to A, chromosome 8 at 119,768,317 bp
  • C to T, chromosome 9 at 20,642,213 bp
  • T to A, chromosome 9 at 106,473,725 bp
  • A to T, chromosome 9 at 107,657,687 bp
  • A to T, chromosome 9 at 110,897,499 bp
  • T to C, chromosome 9 at 120,018,701 bp
  • T to A, chromosome 10 at 23,941,556 bp
  • T to C, chromosome 10 at 50,909,815 bp
  • T to C, chromosome 11 at 69,071,421 bp
  • C to T, chromosome 11 at 69,142,923 bp
  • T to C, chromosome 11 at 72,247,791 bp
  • C to T, chromosome 11 at 78,054,887 bp
  • G to C, chromosome 11 at 78,254,854 bp
  • T to C, chromosome 12 at 109,591,148 bp
  • C to T, chromosome 13 at 6,593,243 bp
  • C to T, chromosome 13 at 52,611,121 bp
  • T to C, chromosome 14 at 34,402,922 bp
  • T to A, chromosome 14 at 120,022,809 bp
  • A to G, chromosome 15 at 76,616,670 bp
  • A to G, chromosome 16 at 18,808,793 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • A to G, chromosome 17 at 78,492,846 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2919 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040504-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.