Strain Name:
C57BL/6J-MtgxR2967Btlr/Mmmh
Stock Number:
040523-MU
Citation ID:
RRID:MMRRC_040523-MU
Other Names:
R2967 (G1), C57BL/6J-MtgxR2967Btlr
Major Collection:

Gene Information

Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, SBP2, 2810012K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75420
Homologene: 11415
Rab1a
Name: RAB1A, member RAS oncogene family
Synonyms: ras-related YPT1 protein, Ypt1, Rab-1, Gtbp, Rab1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19324
HGNC: HGNC:9758
Homologene: 36154
Gan
Name: giant axonal neuropathy
Synonyms: gigaxonin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209239
HGNC: HGNC:4137
Homologene: 32523
Topbp1
Name: topoisomerase (DNA) II binding protein 1
Synonyms: D430026L04Rik, 2810429C13Rik, 1110031N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235559
Homologene: 38262
Pgr
Name: progesterone receptor
Synonyms: NR3C3, PR, 9930019P03Rik, PR-B, PR-A, ENSMUSG00000074510
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18667
HGNC: HGNC:8910
Homologene: 713
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Pwp2
Name: PWP2 periodic tryptophan protein homolog (yeast)
Synonyms: Pwp2, 6530411D08Rik, Pwp2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110816
VEGA: 10
HGNC: HGNC:9711
Homologene: 3702
Ercc8
Name: excision repaiross-complementing rodent repair deficiency, complementation group 8
Synonyms: Csa, 2410022P04Rik, 4631412O06Rik, 2810431L23Rik, B130065P18Rik, Ckn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71991
HGNC: HGNC:3439
Homologene: 62
Zfp653
Name: zinc finger protein 653
Synonyms: E430039K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319601
VEGA: 9
Homologene: 16346
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 59009
Homologene: 10988
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, Golsyn/Syntabulin, 5730410E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 319613
VEGA: 15
Homologene: 9838
Ttf1
Name: transcription termination factor, RNA polymerase I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22130
Homologene: 137223
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213043
Homologene: 84622
Hs2st1
Name: heparan sulfate 2-O-sulfotransferase 1
Synonyms: Hs2st
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23908
HGNC: HGNC:5193
Homologene: 8025
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 628870
Homologene: 46008
Ugt2a1
Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 94215
Homologene: 136808
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Pira13
Name: paired-Ig-like receptor A13
Synonyms: ENSMUSG00000074419, Gm15448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100041146
HGNC: HGNC:6609
Homologene: 134028
Vmn1r81
Name: vomeronasal 1 receptor 81
Synonyms: V1rg9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171244
Homologene: 74327
Cntn6
Name: contactin 6
Synonyms: NB-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53870
HGNC: HGNC:2176
Homologene: 8702
Adgra1
Name: adhesion G protein-coupled receptor A1
Synonyms: 2900059M17Rik, D7Ertd680e, Gpr123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52389
Homologene: 18582
Gsdmc4
Name: gasdermin C4
Synonyms: 9030605I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74548
HGNC: HGNC:7151
Homologene: 69487
Or7a41
Name: olfactory receptor family 7 subfamily A member 41
Synonyms: IF12, MOR139-3, GA_x6K02T2QGN0-2777431-2776472, Olfr57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18357
Homologene: 133620
Eif2s3y
Name: eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
Synonyms: Tfy, Eif-2gy, Spy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 26908
HGNC: HGNC:3267
Homologene: 99414
Bola3
Name: bolA-like 3 (E. coli)
Synonyms: 1810056O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 78653
Homologene: 5288
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 58,322,834 bp
  • T to A, chromosome 2 at 29,065,383 bp
  • T to A, chromosome 3 at 144,465,138 bp
  • C to T, chromosome 4 at 137,511,380 bp
  • A to T, chromosome 5 at 87,474,629 bp
  • A to G, chromosome 5 at 114,166,070 bp
  • T to A, chromosome 6 at 83,349,298 bp
  • G to A, chromosome 6 at 104,726,237 bp
  • T to A, chromosome 7 at 3,822,687 bp
  • G to T, chromosome 7 at 12,260,037 bp
  • G to A, chromosome 7 at 139,875,685 bp
  • C to T, chromosome 8 at 61,226,287 bp
  • A to G, chromosome 8 at 117,183,526 bp
  • T to C, chromosome 9 at 8,901,818 bp
  • A to G, chromosome 9 at 22,065,730 bp
  • T to C, chromosome 9 at 26,881,043 bp
  • C to T, chromosome 9 at 103,342,140 bp
  • A to G, chromosome 10 at 78,182,698 bp
  • A to T, chromosome 10 at 79,035,053 bp
  • T to C, chromosome 10 at 107,777,075 bp
  • T to A, chromosome 11 at 20,223,068 bp
  • T to C, chromosome 13 at 51,670,879 bp
  • C to A, chromosome 13 at 108,160,714 bp
  • T to C, chromosome 15 at 44,746,356 bp
  • T to A, chromosome 15 at 63,902,060 bp
  • A to T, chromosome Y at 1,020,030 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2967 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040523-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.