Strain Name:
C57BL/6J-MtgxR3054Btlr/Mmmh
Stock Number:
040563-MU
Citation ID:
RRID:MMRRC_040563-MU
Other Names:
R3054 (G1), C57BL/6J-MtgxR3054Btlr
Major Collection:

Gene Information

Drd4
Name: dopamine receptor D4
Synonyms: Drd-4, D4R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13491
HGNC: HGNC:3025
Homologene: 20215
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268980
Homologene: 2380
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Map1b
Name: microtubule-associated protein 1B
Synonyms: MAP5, Mtap-5, Mtap5, LC1, Mtap1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Armc6
Name: armadillo repeat containing 6
Synonyms: 2410153K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76813
Homologene: 14121
Ppp4r1
Name: protein phosphatase 4, regulatory subunit 1
Synonyms: Pp4r1, 3110001J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70351
HGNC: HGNC:9320
Homologene: 81737
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Zfp294, Listerin, Rnf160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Zfr
Name: zinc finger RNA binding protein
Synonyms: C920030H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22763
Homologene: 8009
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: 2610042O15Rik, Mms19, C86341, Mms19l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72199
Homologene: 41480
Bard1
Name: BRCA1 associated RING domain 1
Synonyms: ENSMUSG00000060893, ENSMUSG00000073653
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12021
HGNC: HGNC:952
Homologene: 400
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: 3222402C23Rik, Als2cr6, 9430073A21Rik, Alsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Sumf1
Name: sulfatase modifying factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58911
Homologene: 16268
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Rrp9
Name: ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
Synonyms: 55kDa, U3-55k, D9Wsu10e, Rnu3ip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 27966
Homologene: 3452
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54403
Homologene: 55776
Cst3
Name: cystatin C
Synonyms: CysC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13010
HGNC: HGNC:2475
Homologene: 78
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC382129, LOC234973, D430038H04Rik, 9430076A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Tubgcp6
Name: tubulin, gamma complex associated protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328580
Homologene: 32477
Meis3
Name: Meis homeobox 3
Synonyms: Mrg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17537
Homologene: 7425
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: bl, E130113P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231470
Homologene: 23516
Impg2
Name: interphotoreceptor matrix proteoglycan 2
Synonyms: PG10.2, IPM200, Spacrcan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224224
Homologene: 9439
Perm1
Name: PPARGC1 and ESRR induced regulator, muscle 1
Synonyms: 2310042D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74183
Homologene: 135954
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218214
Homologene: 14695
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20460
Homologene: 2283
Timm29
Name: translocase of inner mitochondrial membrane 29
Synonyms: 1810026J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69773
Homologene: 34702
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78016
Homologene: 15814
Ptprn2
Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms: PTP-NP, IA-2 beta, phogrin, IA-2beta, 4930425H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Tctn2
Name: tectonic family member 2
Synonyms: Tect2, 4432405B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67978
Homologene: 11729
Mboat1
Name: membrane bound O-acyltransferase domain containing 1
Synonyms: 9130215M02Rik, Oact1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218121
Homologene: 57467
Polr1e
Name: polymerase (RNA) I polypeptide E
Synonyms: 53kDa, D030019D19Rik, Paf53, Praf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64424
Homologene: 41486
Cntn5
Name: contactin 5
Synonyms: LOC244683, NB-2, A830025P08Rik, 6720426O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244682
HGNC: HGNC:2175
Homologene: 28447
Sh3bp1
Name: SH3-domain binding protein 1
Synonyms: 3BP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20401
Homologene: 7534
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216188
Homologene: 51942
Zfp422-ps
Name: zinc finger protein 422, pseudogene
Synonyms: Krox-25-2, Zfp422-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100416808
Trim5
Name: tripartite motif-containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 667823
Homologene: 75345
5730596B20Rik
Name: RIKEN cDNA 5730596B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 77580
VEGA: 6
A830018L16Rik
Name: RIKEN cDNA A830018L16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320492
Homologene: 14194
Gm9776
Name: predicted gene 9776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328309
VEGA: 13
Larp1b
Name: La ribonucleoprotein domain family, member 1B
Synonyms: 1700108L22Rik, 4933421B21Rik, Larp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214048
Homologene: 103869
Asb7
Name: ankyrin repeat and SOCS box-containing 7
Synonyms: Asb-7, D030055C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 117589
Homologene: 34130
Tjp3
Name: tight junction protein 3
Synonyms: ZO-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27375
VEGA: 10
Homologene: 8458
Utp14b
Name: UTP14B small subunit processome component
Synonyms: jsd, 4932411L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 195434
Homologene: 78703
Gm8444
Name: predicted gene 8444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 667073
VEGA: 15
Gm5591
Name: predicted gene 5591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434171
Homologene: 80005
Cyp2a22
Name: cytochrome P450, family 2, subfamily a, polypeptide 22
Synonyms: EG233005
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233005
Homologene: 69128
Psg29
Name: pregnancy-specific glycoprotein 29
Synonyms: cea17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 114872
Homologene: 83380
Ddo
Name: D-aspartate oxidase
Synonyms: 5730402C02Rik, 5330420D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70503
VEGA: 10
HGNC: HGNC:2727
Homologene: 101531
Gm10013
Name: predicted gene 10013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043629
Radx
Name: RPA1 related single stranded DNA binding protein, X-linked
Synonyms: D330045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 102871
Homologene: 9962
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 11,933,601 bp
  • A to G, chromosome 1 at 54,288,842 bp
  • A to G, chromosome 1 at 59,215,494 bp
  • A to G, chromosome 1 at 71,088,231 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 78,664,725 bp
  • A to G, chromosome 2 at 148,872,031 bp
  • A to T, chromosome 3 at 40,964,100 bp
  • C to T, chromosome 4 at 45,018,724 bp
  • T to A, chromosome 4 at 115,004,966 bp
  • T to C, chromosome 4 at 156,219,876 bp
  • T to C, chromosome 5 at 89,225,948 bp
  • A to T, chromosome 5 at 96,764,943 bp
  • T to A, chromosome 5 at 124,627,144 bp
  • A to T, chromosome 6 at 52,179,128 bp
  • T to C, chromosome 6 at 108,153,204 bp
  • G to T, chromosome 7 at 16,182,453 bp
  • A to G, chromosome 7 at 17,208,802 bp
  • T to C, chromosome 7 at 26,938,829 bp
  • T to C, chromosome 7 at 38,520,634 bp
  • A to T, chromosome 7 at 66,679,211 bp
  • T to C, chromosome 7 at 104,276,593 bp
  • T to C, chromosome 7 at 141,294,479 bp
  • G to T, chromosome 7 at 141,864,041 bp
  • A to T, chromosome 7 at 142,280,352 bp
  • C to A, chromosome 8 at 70,225,149 bp
  • A to G, chromosome 9 at 10,419,071 bp
  • C to T, chromosome 9 at 15,960,496 bp
  • T to C, chromosome 9 at 21,593,591 bp
  • A to G, chromosome 9 at 106,481,896 bp
  • A to G, chromosome 10 at 40,631,742 bp
  • T to C, chromosome 10 at 81,280,507 bp
  • T to C, chromosome 10 at 83,502,472 bp
  • T to C, chromosome 12 at 116,722,133 bp
  • A to T, chromosome 13 at 30,195,741 bp
  • C to T, chromosome 13 at 47,063,077 bp
  • A to G, chromosome 13 at 94,358,650 bp
  • A to G, chromosome 13 at 99,432,742 bp
  • G to A, chromosome 15 at 6,778,231 bp
  • A to G, chromosome 15 at 12,154,507 bp
  • A to G, chromosome 15 at 35,646,361 bp
  • C to T, chromosome 15 at 78,911,422 bp
  • A to T, chromosome 15 at 81,843,644 bp
  • A to T, chromosome 15 at 89,122,603 bp
  • T to C, chromosome 16 at 32,779,029 bp
  • T to A, chromosome 16 at 56,236,773 bp
  • C to T, chromosome 16 at 87,404,073 bp
  • T to C, chromosome 17 at 33,305,161 bp
  • G to T, chromosome 17 at 65,836,079 bp
  • A to T, chromosome 17 at 78,682,892 bp
  • A to T, chromosome 19 at 41,950,088 bp
  • T to A, chromosome X at 139,511,557 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3054 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040563-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.