Strain Name:
C57BL/6J-MtgxR3103Btlr/Mmmh
Stock Number:
040577-MU
Citation ID:
RRID:MMRRC_040577-MU
Other Names:
R3103 (G1), C57BL/6J-MtgxR3103Btlr
Major Collection:

Gene Information

Ptch1
Name: patched 1
Synonyms: wig, A230106A15Rik, Patched 1, Ptc, Ptc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19206
HGNC: HGNC:9585
Homologene: 223
Dpagt1
Name: dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Synonyms: GPT, Gnpta, Dpagt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13478
VEGA: 9
HGNC: HGNC:2995
Homologene: 1058
Trpc2
Name: transient receptor potential cation channel, subfamily C, member 2
Synonyms: trp2, TRPC2a, Trrp2, TRPC2b, mTrp2, 3010009O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22064
Homologene: 135989
Kcmf1
Name: potassium channel modulatory factor 1
Synonyms: 1700094M07Rik, clone DEBT-91, Pmcf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74287
Homologene: 99845
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: b2b1625.2Clo, D230004K18Rik, Megalin, Gp330
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Usp47
Name: ubiquitin specific peptidase 47
Synonyms: A630020C16Rik, 4930502N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74996
Homologene: 9929
Lrrfip2
Name: leucine rich repeat (in FLII) interacting protein 2
Synonyms: 5133400F20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71268
HGNC: HGNC:6703
Homologene: 22476
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Ddx27
Name: DEAD box helicase 27
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228889
Homologene: 6431
Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms: 2410008J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69719
HGNC: HGNC:1424
Homologene: 1412
Cog3
Name: component of oligomeric golgi complex 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 338337
VEGA: 14
Homologene: 5854
Dvl2
Name: dishevelled segment polarity protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13543
HGNC: HGNC:3086
Homologene: 20927
Tfcp2
Name: transcription factor CP2
Synonyms: LBP-1d, Tcfcp2, LBP-1c, LSF, CP-2, LBP1, D230015P20Rik, CP2, UBP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21422
VEGA: 15
Homologene: 4134
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 277939
Homologene: 19524
Cep128
Name: centrosomal protein 128
Synonyms: 5430424K18Rik, 4930534B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75216
Homologene: 35315
Hapln3
Name: hyaluronan and proteoglycan link protein 3
Synonyms: 4930554N11Rik, Lpr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67666
Homologene: 18654
Il31ra
Name: interleukin 31 receptor A
Synonyms: GLM-R, GPL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218624
VEGA: 13
Homologene: 51395
Oit3
Name: oncoprotein induced transcript 3
Synonyms: EF-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18302
Homologene: 7870
Ppt1
Name: palmitoyl-protein thioesterase 1
Synonyms: CLN1, 9530043G02Rik, D4Ertd184e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19063
HGNC: HGNC:9325
Homologene: 7488
Zfp148
Name: zinc finger protein 148
Synonyms: ZBP-89, 2210405J08Rik, beta enolase repressor factor 1, BERF-1, BFCOL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22661
VEGA: 16
Homologene: 8003
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Skor2
Name: SKI family transcriptional corepressor 2
Synonyms: Corl2, Fussel18, Gm7348
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 664805
VEGA: 18
Homologene: 64797
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: Zfh4, Zfh-4, C130041O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 80892
Homologene: 23477
Ets1
Name: E26 avian leukemia oncogene 1, 5' domain
Synonyms: Tpl1, p51Ets-1, vs, Ets-1, p42Ets-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23871
HGNC: HGNC:3488
Homologene: 3837
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: Dm15, DM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Gpr63
Name: G protein-coupled receptor 63
Synonyms: PSP24beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 81006
Homologene: 12759
Plb1
Name: phospholipase B1
Synonyms: 4632413E21Rik, 4930539A06Rik, 4930433E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665270
Homologene: 82108
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Slc13a5
Name: solute carrier family 13 (sodium-dependent citrate transporter), member 5
Synonyms: NaC2/NaCT, Indy, mINDY, Nact
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237831
Homologene: 21941
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: EG637873, Casr-rs2, Gprc2a-rs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637873
Homologene: 129683
Klf17
Name: Kruppel-like factor 17
Synonyms: Zfp393, D4Ertd561e, 7420700M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75753
Homologene: 12621
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: C130074L01Rik, 6330407A06Rik, Giantin, F730017E11Rik, Gm6840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Olfr50
Name: olfactory receptor 50
Synonyms: MOR136-6, GA_x6K02T2NLDC-33487752-33488690, ID3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18350
Homologene: 74212
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Fmi1, Adgrc3, flamingo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Cts8
Name: cathepsin 8
Synonyms: Epcs68, CTS2, Epcs70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 56094
VEGA: 13
Homologene: 129897
Serpinb11
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
Synonyms: 2310046M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66957
Homologene: 41653
Adap2
Name: ArfGAP with dual PH domains 2
Synonyms: centaurin alpha 2, Centa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216991
Homologene: 10179
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: C330005M16Rik, Papl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101744
Homologene: 23924
Bace2
Name: beta-site APP-cleaving enzyme 2
Synonyms: CEAP1, ARP1, BAE2, ALP56, ASP21, CDA13, 1110059C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56175
VEGA: 16
HGNC: HGNC:934
Homologene: 22696
Grik2
Name: glutamate receptor, ionotropic, kainate 2 (beta 2)
Synonyms: Glur-6, Glur6, Glurbeta2, C130030K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14806
HGNC: HGNC:4580
Homologene: 40717
Olfr555
Name: olfactory receptor 555
Synonyms: GA_x6K02T2PBJ9-5375442-5376389, MOR10-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259107
Homologene: 51817
Ctnna2
Name: catenin (cadherin associated protein), alpha 2
Synonyms: alpha(N)-catenin, Catna2, alpha N-catenin, Catna, chp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Ipp
Name: IAP promoted placental gene
Synonyms: Mipp, D4Jhu8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16351
HGNC: HGNC:6108
Homologene: 4309
Olfr403
Name: olfactory receptor 403
Synonyms: GA_x6K02T2P1NL-4348188-4349129, MOR125-5_p, IA7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 404316
HGNC: HGNC:8179
Homologene: 8219
Bpifc
Name: BPI fold containing family C
Synonyms: Bpil2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 270757
Homologene: 18383
Gcm1
Name: glial cells missing homolog 1
Synonyms: glial cell deficient, Gcm 1, GCMa, Gcm1-rs1, Gcm a, glide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14531
VEGA: 9
HGNC: HGNC:4197
Homologene: 2702
Svs5
Name: seminal vesicle secretory protein 5
Synonyms: Svp-1, SVS V, seminal vesicle protein F, Svp5, Svp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20944
Homologene: 49199
Pstpip2
Name: proline-serine-threonine phosphatase-interacting protein 2
Synonyms: cmo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19201
VEGA: 18
HGNC: HGNC:9581
Homologene: 69150
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 107,377,608 bp
  • T to C, chromosome 2 at 36,793,562 bp
  • C to T, chromosome 2 at 69,431,984 bp
  • A to T, chromosome 2 at 164,333,393 bp
  • T to A, chromosome 2 at 167,026,246 bp
  • A to G, chromosome 3 at 5,399,326 bp
  • G to T, chromosome 3 at 38,891,940 bp
  • G to A, chromosome 4 at 25,007,353 bp
  • G to T, chromosome 4 at 116,524,249 bp
  • T to A, chromosome 4 at 117,760,608 bp
  • T to C, chromosome 4 at 122,836,307 bp
  • T to C, chromosome 5 at 31,061,674 bp
  • T to A, chromosome 5 at 32,328,029 bp
  • A to G, chromosome 6 at 72,861,847 bp
  • T to C, chromosome 6 at 77,653,144 bp
  • A to G, chromosome 7 at 19,087,654 bp
  • A to G, chromosome 7 at 28,610,984 bp
  • C to T, chromosome 7 at 29,074,948 bp
  • T to A, chromosome 7 at 42,266,643 bp
  • T to C, chromosome 7 at 79,121,736 bp
  • A to G, chromosome 7 at 100,395,252 bp
  • A to T, chromosome 7 at 102,095,234 bp
  • T to C, chromosome 7 at 102,659,481 bp
  • T to A, chromosome 7 at 112,067,078 bp
  • C to T, chromosome 8 at 15,917,405 bp
  • T to A, chromosome 9 at 32,728,798 bp
  • A to G, chromosome 9 at 44,327,995 bp
  • A to G, chromosome 9 at 78,064,452 bp
  • A to G, chromosome 9 at 108,837,139 bp
  • A to T, chromosome 9 at 111,222,210 bp
  • A to G, chromosome 10 at 49,240,772 bp
  • A to G, chromosome 10 at 59,438,891 bp
  • A to G, chromosome 10 at 85,993,422 bp
  • C to A, chromosome 11 at 70,008,869 bp
  • A to T, chromosome 11 at 72,257,388 bp
  • G to A, chromosome 11 at 74,196,075 bp
  • G to T, chromosome 11 at 80,157,033 bp
  • T to A, chromosome 12 at 91,019,344 bp
  • T to A, chromosome 13 at 61,250,958 bp
  • T to C, chromosome 13 at 63,543,209 bp
  • A to T, chromosome 13 at 96,482,506 bp
  • C to A, chromosome 13 at 112,530,351 bp
  • T to C, chromosome 14 at 75,747,201 bp
  • A to T, chromosome 15 at 100,525,600 bp
  • T to C, chromosome 16 at 33,468,085 bp
  • A to G, chromosome 16 at 36,894,849 bp
  • T to C, chromosome 16 at 97,422,001 bp
  • A to T, chromosome 18 at 76,859,278 bp
  • T to C, chromosome 18 at 77,871,777 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3103 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040577-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.