Strain Name:
C57BL/6J-MtgxR3104Btlr/Mmmh
Stock Number:
040578-MU
Citation ID:
RRID:MMRRC_040578-MU
Other Names:
R3104 (G1), C57BL/6J-MtgxR3104Btlr
Major Collection:

Gene Information

Sparcl1
Name: SPARC-like 1
Synonyms: Ecm2, Sc1, hevin, mast9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13602
Homologene: 3438
Crhr2
Name: corticotropin releasing hormone receptor 2
Synonyms: CRF-R2, CRF 2 receptor, CRH-R2, CRFR2beta, Crfr2, CRFR2alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12922
HGNC: HGNC:2358
Homologene: 55612
Etv1
Name: ets variant 1
Synonyms: ER81, Etsrp81
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 14009
HGNC: HGNC:3490
Homologene: 3636
Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Synonyms: aromatase, ArKO, Cyp19, Int5, Ar, Int-5, p450arom
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13075
VEGA: 9
HGNC: HGNC:2594
Homologene: 30955
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: Ocam, RNCAM, R4B12 antigen, Ncam-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: Catnal1, ACRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Yes1
Name: YES proto-oncogene 1, Src family tyrosine kinase
Synonyms: Yes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22612
Homologene: 55900
Nphs1
Name: nephrosis 1, nephrin
Synonyms: nephrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54631
HGNC: HGNC:7908
Homologene: 20974
Tkfc
Name: triokinase, FMN cyclase
Synonyms: Dak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225913
VEGA: 19
Homologene: 56710
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Walp3, Tip5, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, jdf2, D7H15F37S1, rjs, D15F32S1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 4921511H13Rik, 5730405K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207932
Homologene: 45941
Ccdc191
Name: coiled-coil domain containing 191
Synonyms: 2610015P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 212153
Homologene: 19484
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269608
Homologene: 10768
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: E430018P19Rik, 8030453L17Rik, KMT2H, chromatin remodeling factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 192195
Homologene: 10225
Sars
Name: seryl-aminoacyl-tRNA synthetase
Synonyms: Strs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20226
Homologene: 4751
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14426
HGNC: HGNC:4126
Homologene: 74511
Coch
Name: cochlin
Synonyms: D12H14S564E, Coch-5B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 12810
VEGA: 12
HGNC: HGNC:2180
Homologene: 20868
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: 2810423A18Rik, GFAT, GFA, GFAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Cdh9
Name: cadherin 9
Synonyms: T1-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12565
HGNC: HGNC:1768
Homologene: 9450
Dbx1
Name: developing brain homeobox 1
Synonyms: Mmox C, Dbx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13172
Homologene: 19002
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A230083H22Rik, A330102H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Emc10
Name: ER membrane protein complex subunit 10
Synonyms: Mirta22, 5430410O10Rik, 2310044H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69683
Homologene: 18036
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99470
Homologene: 26431
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 84092
Homologene: 3782
Tmem51
Name: transmembrane protein 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 214359
Homologene: 9966
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94109
Homologene: 69536
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Itpr5, Ip3r2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Lmod2
Name: leiomodin 2 (cardiac)
Synonyms: C-Lmod
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 93677
HGNC: HGNC:6648
Homologene: 28302
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: Als2cr2, PRO1038, D1Ucla2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227154
Homologene: 10237
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329178
Homologene: 122243
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Usp29
Name: ubiquitin specific peptidase 29
Synonyms: Ocat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57775
Homologene: 49641
Sfmbt1
Name: Scm-like with four mbt domains 1
Synonyms: 9330180L21Rik, 4930442N21Rik, Smr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54650
Homologene: 9472
Plce1
Name: phospholipase C, epsilon 1
Synonyms: 4933403A21Rik, PLCepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74055
Homologene: 9478
Pcdhga11
Name: protocadherin gamma subfamily A, 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93723
HGNC: HGNC:8698
Homologene: 110934
Gtf2ird2
Name: GTF2I repeat domain containing 2
Synonyms: 1700012P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 114674
Homologene: 24941
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 338349
Homologene: 9805
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Fam187b
Name: family with sequence similarity 187, member B
Synonyms: 1700020B09Rik, Tmem162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76415
Homologene: 138431
Fam124b
Name: family with sequence similarity 124, member B
Synonyms: A830043J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241128
Homologene: 65263
Il1rap
Name: interleukin 1 receptor accessory protein
Synonyms: IL-1R AcP, IL-1RAcP, 6430709H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 16180
HGNC: HGNC:5995
Homologene: 1643
Tmigd1
Name: transmembrane and immunoglobulin domain containing 1
Synonyms: 2010002A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66601
Homologene: 41641
Tsga10
Name: testis specific 10
Synonyms: Mtsga10, 4933432N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 211484
Homologene: 23531
Prkag2
Name: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Synonyms: 2410051C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108099
HGNC: HGNC:9386
Homologene: 136125
Vmn1r38
Name: vomeronasal 1 receptor 38
Synonyms: V1rc13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171186
Homologene: 110800
Olfr1094
Name: olfactory receptor 1094
Synonyms: GA_x6K02T2Q125-48321457-48322449, MOR179-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258362
Homologene: 133609
Cyp2c68
Name: cytochrome P450, family 2, subfamily c, polypeptide 68
Synonyms: 9030012A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 433247
Homologene: 74936
Tm4sf4
Name: transmembrane 4 superfamily member 4
Synonyms: il-TMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229302
Homologene: 3393
Bmp4
Name: bone morphogenetic protein 4
Synonyms: Bmp2b1, Bmp2b, Bmp2b-1, Bmp-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12159
HGNC: HGNC:1071
Homologene: 7247
Gm5174
Name: predicted gene 5174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382395
VEGA: 10
Homologene: 141143
Tmem212
Name: transmembrane protein 212
Synonyms: E030011K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 208613
Homologene: 28471
Sppl2b
Name: signal peptide peptidase like 2B
Synonyms: 3110056O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73218
VEGA: 10
Homologene: 10605
Osgep
Name: O-sialoglycoprotein endopeptidase
Synonyms: PRSMG1, GCPL-1, 1500019L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66246
Homologene: 6395
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 37,801,791 bp
  • C to A, chromosome 1 at 58,992,291 bp
  • G to A, chromosome 1 at 66,623,291 bp
  • T to A, chromosome 1 at 80,213,031 bp
  • T to C, chromosome 1 at 90,816,302 bp
  • A to G, chromosome 1 at 135,000,472 bp
  • T to C, chromosome 2 at 86,829,691 bp
  • T to C, chromosome 2 at 126,758,512 bp
  • T to G, chromosome 3 at 3,652,856 bp
  • T to C, chromosome 3 at 27,884,870 bp
  • C to T, chromosome 3 at 57,437,622 bp
  • T to A, chromosome 3 at 89,054,386 bp
  • A to G, chromosome 3 at 104,051,320 bp
  • C to T, chromosome 3 at 108,429,305 bp
  • G to A, chromosome 4 at 56,813,246 bp
  • C to T, chromosome 4 at 84,957,169 bp
  • T to C, chromosome 4 at 142,037,724 bp
  • C to T, chromosome 4 at 152,112,178 bp
  • T to A, chromosome 5 at 24,871,069 bp
  • T to C, chromosome 5 at 32,653,171 bp
  • T to C, chromosome 5 at 104,093,337 bp
  • G to A, chromosome 5 at 134,208,915 bp
  • A to C, chromosome 6 at 24,604,472 bp
  • G to A, chromosome 6 at 55,123,673 bp
  • T to C, chromosome 6 at 66,776,446 bp
  • A to G, chromosome 6 at 87,057,646 bp
  • A to T, chromosome 6 at 146,312,837 bp
  • T to A, chromosome 7 at 6,962,053 bp
  • C to A, chromosome 7 at 30,467,540 bp
  • A to G, chromosome 7 at 30,977,240 bp
  • G to A, chromosome 7 at 44,493,192 bp
  • A to T, chromosome 7 at 49,636,669 bp
  • T to A, chromosome 7 at 56,135,355 bp
  • A to G, chromosome 8 at 17,027,231 bp
  • T to C, chromosome 9 at 54,186,799 bp
  • A to G, chromosome 10 at 80,867,491 bp
  • A to G, chromosome 10 at 86,656,655 bp
  • T to C, chromosome 10 at 99,109,381 bp
  • AGCGGCGGTACTTGCGGG to AG, chromosome 10 at 128,125,077 bp
  • A to G, chromosome 11 at 76,910,298 bp
  • A to G, chromosome 12 at 38,861,397 bp
  • A to G, chromosome 12 at 51,603,421 bp
  • G to A, chromosome 14 at 30,817,796 bp
  • G to A, chromosome 14 at 46,385,981 bp
  • T to C, chromosome 14 at 50,916,829 bp
  • T to C, chromosome 15 at 16,855,814 bp
  • T to A, chromosome 16 at 22,575,341 bp
  • A to G, chromosome 16 at 26,722,752 bp
  • T to C, chromosome 16 at 43,931,210 bp
  • A to G, chromosome 16 at 81,465,710 bp
  • C to T, chromosome 16 at 90,795,443 bp
  • A to G, chromosome 18 at 37,821,674 bp
  • G to T, chromosome 19 at 10,596,993 bp
  • T to A, chromosome 19 at 17,119,156 bp
  • C to T, chromosome 19 at 38,620,519 bp
  • C to T, chromosome 19 at 39,734,313 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3104 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040578-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.